HSP90B1 (heat shock protein 90 beta family member 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7184 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Heat shock protein 90 beta family member 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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HSP90B1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q23.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | P14625 | |||||||||||||||
| Protein name | Endoplasmin (EC 3.6.4.-) (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog) | |||||||||||||||
| Protein function | ATP-dependent chaperone involved in the processing of proteins in the endoplasmic reticulum, regulating their transport (PubMed:23572575, PubMed:39509507). Together with MESD, acts as a modulator of the Wnt pathway by promoting the folding of LR | |||||||||||||||
| PDB | 4NH9 , 7ULL | |||||||||||||||
| Family and domains |
Pfam
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| Sequence | ||||||||||||||||
| Sequence length | 803 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||