TACC1 (transforming acidic coiled-coil containing protein 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6867 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Transforming acidic coiled-coil containing protein 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TACC1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Ga55 |
Chromosome
Chromosome number
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8 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p11.22 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | O75410 | ||||||||||
Protein name | Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) | ||||||||||
Protein function | Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways (PubMed:20078863). Might promote the nuclear localization of the receptors (PubMed:20078863). Likely involved | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expressi | ||||||||||
Sequence |
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Sequence length | 805 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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