| GO ID |
Ontology |
Definition |
Evidence |
Reference |
|
GO:0000045 |
Process |
Autophagosome assembly |
IDA |
28890335 |
|
GO:0000166 |
Function |
Nucleotide binding |
IEA |
|
|
GO:0001525 |
Process |
Angiogenesis |
IEA |
|
|
GO:0001775 |
Process |
Cell activation |
IEA |
|
|
GO:0001775 |
Process |
Cell activation |
ISS |
|
|
GO:0001784 |
Function |
Phosphotyrosine residue binding |
IPI |
20624904 |
|
GO:0001819 |
Process |
Positive regulation of cytokine production |
IEA |
|
|
GO:0001820 |
Process |
Serotonin secretion |
IEA |
|
|
GO:0001945 |
Process |
Lymph vessel development |
IEA |
|
|
GO:0001945 |
Process |
Lymph vessel development |
ISS |
|
|
GO:0002092 |
Process |
Positive regulation of receptor internalization |
IEA |
|
|
GO:0002223 |
Process |
Stimulatory C-type lectin receptor signaling pathway |
IEA |
|
|
GO:0002223 |
Process |
Stimulatory C-type lectin receptor signaling pathway |
ISS |
|
|
GO:0002223 |
Process |
Stimulatory C-type lectin receptor signaling pathway |
TAS |
|
|
GO:0002250 |
Process |
Adaptive immune response |
IBA |
|
|
GO:0002250 |
Process |
Adaptive immune response |
IEA |
|
|
GO:0002250 |
Process |
Adaptive immune response |
ISS |
|
|
GO:0002281 |
Process |
Macrophage activation involved in immune response |
IBA |
|
|
GO:0002281 |
Process |
Macrophage activation involved in immune response |
IEA |
|
|
GO:0002281 |
Process |
Macrophage activation involved in immune response |
ISS |
|
|
GO:0002283 |
Process |
Neutrophil activation involved in immune response |
IBA |
|
|
GO:0002283 |
Process |
Neutrophil activation involved in immune response |
IEA |
|
|
GO:0002283 |
Process |
Neutrophil activation involved in immune response |
ISS |
|
|
GO:0002366 |
Process |
Leukocyte activation involved in immune response |
IEA |
|
|
GO:0002366 |
Process |
Leukocyte activation involved in immune response |
ISS |
|
|
GO:0002376 |
Process |
Immune system process |
IEA |
|
|
GO:0002554 |
Process |
Serotonin secretion by platelet |
IEA |
|
|
GO:0002554 |
Process |
Serotonin secretion by platelet |
ISS |
|
|
GO:0002752 |
Process |
Cell surface pattern recognition receptor signaling pathway |
IMP |
19358895 |
|
GO:0002862 |
Process |
Negative regulation of inflammatory response to antigenic stimulus |
TAS |
|
|
GO:0004672 |
Function |
Protein kinase activity |
IDA |
18818202 |
|
GO:0004672 |
Function |
Protein kinase activity |
IEA |
|
|
GO:0004672 |
Function |
Protein kinase activity |
NAS |
12885943 |
|
GO:0004674 |
Function |
Protein serine/threonine kinase activity |
IDA |
23071339 |
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
EXP |
8629002, 8657103, 10648173, 17993265, 18818202, 22041900 |
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
IBA |
|
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
IDA |
34634301 |
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
IEA |
|
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
IMP |
33782605 |
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
ISS |
|
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
NAS |
28386764 |
|
GO:0004713 |
Function |
Protein tyrosine kinase activity |
TAS |
|
|
GO:0004715 |
Function |
Non-membrane spanning protein tyrosine kinase activity |
IDA |
8163536, 11606584 |
|
GO:0004715 |
Function |
Non-membrane spanning protein tyrosine kinase activity |
IEA |
|
|
GO:0004715 |
Function |
Non-membrane spanning protein tyrosine kinase activity |
IGI |
14656219 |
|
GO:0004715 |
Function |
Non-membrane spanning protein tyrosine kinase activity |
IMP |
15509800 |
|
GO:0004715 |
Function |
Non-membrane spanning protein tyrosine kinase activity |
TAS |
|
|
GO:0005102 |
Function |
Signaling receptor binding |
IPI |
31145836 |
|
GO:0005178 |
Function |
Integrin binding |
IPI |
12885943 |
|
GO:0005515 |
Function |
Protein binding |
IPI |
7761456, 8627166, 8647200, 8657103, 8798676, 8810294, 9280292, 9698567, 11940607, 12051764, 15536084, 16273093, 18273061, 19843936, 20133729, 20585042, 20713593, 21044950, 21516116, 22019427, 22624718, 23001182, 23299888, 24525236, 24728074, 25416956, 25605870, 25814554, 28086240, 31 |
|
GO:0005524 |
Function |
ATP binding |
IEA |
|
|
GO:0005634 |
Component |
Nucleus |
IDA |
23071339 |
|
GO:0005737 |
Component |
Cytoplasm |
IDA |
23071339 |
|
GO:0005737 |
Component |
Cytoplasm |
IEA |
|
|
GO:0005737 |
Component |
Cytoplasm |
ISS |
|
|
GO:0005829 |
Component |
Cytosol |
IC |
8163536 |
|
GO:0005829 |
Component |
Cytosol |
IEA |
|
|
GO:0005829 |
Component |
Cytosol |
TAS |
|
|
GO:0005886 |
Component |
Plasma membrane |
IBA |
|
|
GO:0005886 |
Component |
Plasma membrane |
IEA |
|
|
GO:0005886 |
Component |
Plasma membrane |
TAS |
|
|
GO:0006468 |
Process |
Protein phosphorylation |
IDA |
17681949 |
|
GO:0006606 |
Process |
Protein import into nucleus |
IMP |
23071339 |
|
GO:0007159 |
Process |
Leukocyte cell-cell adhesion |
IDA |
12885943 |
|
GO:0007159 |
Process |
Leukocyte cell-cell adhesion |
IEA |
|
|
GO:0007166 |
Process |
Cell surface receptor signaling pathway |
IEA |
|
|
GO:0007167 |
Process |
Enzyme-linked receptor protein signaling pathway |
IEA |
|
|
GO:0007229 |
Process |
Integrin-mediated signaling pathway |
IEA |
|
|
GO:0007229 |
Process |
Integrin-mediated signaling pathway |
ISS |
|
|
GO:0007229 |
Process |
Integrin-mediated signaling pathway |
NAS |
12885943 |
|
GO:0009887 |
Process |
Animal organ morphogenesis |
TAS |
7477352 |
|
GO:0010507 |
Process |
Negative regulation of autophagy |
IDA |
32561715 |
|
GO:0010508 |
Process |
Positive regulation of autophagy |
IDA |
22017875, 22017876 |
|
GO:0010543 |
Process |
Regulation of platelet activation |
IEA |
|
|
GO:0010543 |
Process |
Regulation of platelet activation |
ISS |
|
|
GO:0010803 |
Process |
Regulation of tumor necrosis factor-mediated signaling pathway |
IMP |
19151749 |
|
GO:0016020 |
Component |
Membrane |
IEA |
|
|
GO:0016170 |
Function |
Interleukin-15 receptor binding |
IPI |
15123770 |
|
GO:0016301 |
Function |
Kinase activity |
IDA |
9490415 |
|
GO:0016301 |
Function |
Kinase activity |
IEA |
|
|
GO:0016740 |
Function |
Transferase activity |
IEA |
|
|
GO:0018108 |
Process |
Peptidyl-tyrosine phosphorylation |
ISS |
|
|
GO:0019370 |
Process |
Leukotriene biosynthetic process |
IEA |
|
|
GO:0019722 |
Process |
Calcium-mediated signaling |
IEA |
|
|
GO:0019815 |
Component |
B cell receptor complex |
IEA |
|
|
GO:0019901 |
Function |
Protein kinase binding |
IEA |
|
|
GO:0019902 |
Function |
Phosphatase binding |
IEA |
|
|
GO:0030168 |
Process |
Platelet activation |
TAS |
|
|
GO:0030183 |
Process |
B cell differentiation |
IEA |
|
|
GO:0030593 |
Process |
Neutrophil chemotaxis |
IDA |
12885943 |
|
GO:0031334 |
Process |
Positive regulation of protein-containing complex assembly |
IMP |
22267217 |
|
GO:0031623 |
Process |
Receptor internalization |
IEA |
|
|
GO:0031623 |
Process |
Receptor internalization |
ISS |
|
|
GO:0031669 |
Process |
Cellular response to nutrient levels |
IDA |
32561715 |
|
GO:0032009 |
Component |
Early phagosome |
IEA |
|
|
GO:0032009 |
Component |
Early phagosome |
ISS |
|
|
GO:0032481 |
Process |
Positive regulation of type I interferon production |
IEA |
|
|
GO:0032725 |
Process |
Positive regulation of granulocyte macrophage colony-stimulating factor production |
IEA |
|
|
GO:0032733 |
Process |
Positive regulation of interleukin-10 production |
IMP |
19358895 |
|
GO:0032735 |
Process |
Positive regulation of interleukin-12 production |
IMP |
19358895 |
|
GO:0032752 |
Process |
Positive regulation of interleukin-3 production |
IEA |
|
|
GO:0032753 |
Process |
Positive regulation of interleukin-4 production |
IEA |
|
|
GO:0032753 |
Process |
Positive regulation of interleukin-4 production |
ISS |
|
|
GO:0032755 |
Process |
Positive regulation of interleukin-6 production |
IMP |
19358895 |
|
GO:0032757 |
Process |
Positive regulation of interleukin-8 production |
IMP |
25251945 |
|
GO:0032760 |
Process |
Positive regulation of tumor necrosis factor production |
IMP |
19358895 |
|
GO:0032765 |
Process |
Positive regulation of mast cell cytokine production |
IEA |
|
|
GO:0032928 |
Process |
Regulation of superoxide anion generation |
IEA |
|
|
GO:0032928 |
Process |
Regulation of superoxide anion generation |
ISS |
|
|
GO:0032930 |
Process |
Positive regulation of superoxide anion generation |
IMP |
19358895 |
|
GO:0032991 |
Component |
Protein-containing complex |
IDA |
23071339 |
|
GO:0032991 |
Component |
Protein-containing complex |
IEA |
|
|
GO:0033630 |
Process |
Positive regulation of cell adhesion mediated by integrin |
IBA |
|
|
GO:0033630 |
Process |
Positive regulation of cell adhesion mediated by integrin |
IEA |
|
|
GO:0033630 |
Process |
Positive regulation of cell adhesion mediated by integrin |
ISS |
|
|
GO:0035325 |
Function |
Toll-like receptor binding |
IEA |
|
|
GO:0035556 |
Process |
Intracellular signal transduction |
IDA |
11606584, 15509800 |
|
GO:0035556 |
Process |
Intracellular signal transduction |
IEA |
|
|
GO:0035556 |
Process |
Intracellular signal transduction |
IEA |
|
|
GO:0035556 |
Process |
Intracellular signal transduction |
IGI |
14656219 |
|
GO:0035556 |
Process |
Intracellular signal transduction |
IMP |
11606584, 32514138 |
|
GO:0035556 |
Process |
Intracellular signal transduction |
ISS |
|
|
GO:0038063 |
Process |
Collagen-activated tyrosine kinase receptor signaling pathway |
IEA |
|
|
GO:0038095 |
Process |
Fc-epsilon receptor signaling pathway |
TAS |
|
|
GO:0038096 |
Process |
Fc-gamma receptor signaling pathway involved in phagocytosis |
TAS |
|
|
GO:0038156 |
Process |
Interleukin-3-mediated signaling pathway |
IEA |
|
|
GO:0038156 |
Process |
Interleukin-3-mediated signaling pathway |
ISS |
|
|
GO:0038202 |
Process |
TORC1 signaling |
IDA |
12087098 |
|
GO:0042101 |
Component |
T cell receptor complex |
IDA |
8176201 |
|
GO:0042101 |
Component |
T cell receptor complex |
IEA |
|
|
GO:0042169 |
Function |
SH2 domain binding |
IEA |
|
|
GO:0042492 |
Process |
Gamma-delta T cell differentiation |
IEA |
|
|
GO:0042742 |
Process |
Defense response to bacterium |
IEA |
|
|
GO:0042742 |
Process |
Defense response to bacterium |
ISS |
|
|
GO:0043274 |
Function |
Phospholipase binding |
IPI |
14656219, 32514138 |
|
GO:0043303 |
Process |
Mast cell degranulation |
IEA |
|
|
GO:0043306 |
Process |
Positive regulation of mast cell degranulation |
IEA |
|
|
GO:0043313 |
Process |
Regulation of neutrophil degranulation |
IEA |
|
|
GO:0043313 |
Process |
Regulation of neutrophil degranulation |
ISS |
|
|
GO:0043366 |
Process |
Beta selection |
IEA |
|
|
GO:0043410 |
Process |
Positive regulation of MAPK cascade |
IEA |
|
|
GO:0045087 |
Process |
Innate immune response |
IEA |
|
|
GO:0045087 |
Process |
Innate immune response |
ISS |
|
|
GO:0045579 |
Process |
Positive regulation of B cell differentiation |
IEA |
|
|
GO:0045579 |
Process |
Positive regulation of B cell differentiation |
IMP |
18369315 |
|
GO:0045588 |
Process |
Positive regulation of gamma-delta T cell differentiation |
IEA |
|
|
GO:0045621 |
Process |
Positive regulation of lymphocyte differentiation |
IEA |
|
|
GO:0045780 |
Process |
Positive regulation of bone resorption |
IEA |
|
|
GO:0045780 |
Process |
Positive regulation of bone resorption |
ISS |
|
|
GO:0046638 |
Process |
Positive regulation of alpha-beta T cell differentiation |
IEA |
|
|
GO:0046641 |
Process |
Positive regulation of alpha-beta T cell proliferation |
IEA |
|
|
GO:0048514 |
Process |
Blood vessel morphogenesis |
IEA |
|
|
GO:0048514 |
Process |
Blood vessel morphogenesis |
ISS |
|
|
GO:0050764 |
Process |
Regulation of phagocytosis |
IEA |
|
|
GO:0050764 |
Process |
Regulation of phagocytosis |
ISS |
|
|
GO:0050776 |
Process |
Regulation of immune response |
IEA |
|
|
GO:0050850 |
Process |
Positive regulation of calcium-mediated signaling |
IEA |
|
|
GO:0050853 |
Process |
B cell receptor signaling pathway |
IBA |
|
|
GO:0050853 |
Process |
B cell receptor signaling pathway |
IEA |
|
|
GO:0050853 |
Process |
B cell receptor signaling pathway |
IMP |
15509800 |
|
GO:0050853 |
Process |
B cell receptor signaling pathway |
ISS |
|
|
GO:0050900 |
Process |
Leukocyte migration |
IEA |
|
|
GO:0051090 |
Process |
Regulation of DNA-binding transcription factor activity |
IMP |
23071339 |
|
GO:0051649 |
Process |
Establishment of localization in cell |
IEA |
|
|
GO:0070372 |
Process |
Regulation of ERK1 and ERK2 cascade |
IEA |
|
|
GO:0070372 |
Process |
Regulation of ERK1 and ERK2 cascade |
ISS |
|
|
GO:0071226 |
Process |
Cellular response to molecule of fungal origin |
IEA |
|
|
GO:0071226 |
Process |
Cellular response to molecule of fungal origin |
ISS |
|
|
GO:0071396 |
Process |
Cellular response to lipid |
IMP |
32514138 |
|
GO:0071404 |
Process |
Cellular response to low-density lipoprotein particle stimulus |
IEA |
|
|
GO:0071404 |
Process |
Cellular response to low-density lipoprotein particle stimulus |
ISS |
|
|
GO:0071639 |
Process |
Positive regulation of monocyte chemotactic protein-1 production |
IMP |
25251945 |
|
GO:0090237 |
Process |
Regulation of arachidonate secretion |
IEA |
|
|
GO:0090237 |
Process |
Regulation of arachidonate secretion |
ISS |
|
|
GO:0090330 |
Process |
Regulation of platelet aggregation |
IEA |
|
|
GO:0090330 |
Process |
Regulation of platelet aggregation |
ISS |
|
|
GO:0097110 |
Function |
Scaffold protein binding |
IPI |
11606584 |
|
GO:0097190 |
Process |
Apoptotic signaling pathway |
IMP |
22267217 |
|
GO:0097242 |
Process |
Amyloid-beta clearance |
IDA |
27477018 |
|
GO:0120162 |
Process |
Positive regulation of cold-induced thermogenesis |
IEA |
|
|
GO:0120162 |
Process |
Positive regulation of cold-induced thermogenesis |
ISS |
29235464 |
|
GO:1904262 |
Process |
Negative regulation of TORC1 signaling |
IDA |
22017875, 22017876 |
|
GO:1904263 |
Process |
Positive regulation of TORC1 signaling |
IDA |
34634301 |
|
GO:1904646 |
Process |
Cellular response to amyloid-beta |
IDA |
29518356 |
|
GO:1990858 |
Process |
Cellular response to lectin |
IEA |
|
|
GO:1990858 |
Process |
Cellular response to lectin |
ISS |
|