Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	6652
Gene name	Sorbitol dehydrogenase
Gene symbol	SORD
Synonyms (NCBI Gene)	HEL-S-95nHMNR8RDHSDHSORD1SORDDXDH
Chromosome	15
Chromosome location	15q21.1
Summary	Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the de

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027448	hsa-miR-98-5p	Microarray	19088304
MIRT047657	hsa-miR-10a-5p	CLASH	23622248
MIRT042343	hsa-miR-484	CLASH	23622248
MIRT653256	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT653255	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT653254	hsa-miR-1248	HITS-CLIP	23824327
MIRT653253	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653252	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653251	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT653250	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT653249	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT653248	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT653247	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT653246	hsa-miR-9-3p	HITS-CLIP	23824327
MIRT653245	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT630238	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT630237	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT630236	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT630235	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT630234	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT630233	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT630232	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT630231	hsa-miR-4797-3p	HITS-CLIP	23824327
MIRT630230	hsa-miR-4264	HITS-CLIP	23824327
MIRT630229	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT630228	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT630227	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT630226	hsa-miR-612	HITS-CLIP	23824327
MIRT630225	hsa-miR-6860	HITS-CLIP	23824327
MIRT630224	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630223	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630222	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630221	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT630220	hsa-miR-4284	HITS-CLIP	23824327
MIRT630219	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630218	hsa-miR-3945	HITS-CLIP	23824327
MIRT630217	hsa-miR-4253	HITS-CLIP	23824327
MIRT630216	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT630215	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT653256	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT653255	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT653254	hsa-miR-1248	HITS-CLIP	23824327
MIRT653253	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT653252	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT653251	hsa-miR-302a-5p	HITS-CLIP	23824327
MIRT653250	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT653249	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT653248	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT653247	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT653246	hsa-miR-9-3p	HITS-CLIP	23824327
MIRT653245	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT630238	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT630237	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT630236	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT630235	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT630234	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT630233	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT630232	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT630231	hsa-miR-4797-3p	HITS-CLIP	23824327
MIRT630230	hsa-miR-4264	HITS-CLIP	23824327
MIRT630229	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT630228	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT630227	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT630226	hsa-miR-612	HITS-CLIP	23824327
MIRT630225	hsa-miR-6860	HITS-CLIP	23824327
MIRT630224	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT630223	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT630222	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT630221	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT630220	hsa-miR-4284	HITS-CLIP	23824327
MIRT630219	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630218	hsa-miR-3945	HITS-CLIP	23824327
MIRT630217	hsa-miR-4253	HITS-CLIP	23824327
MIRT630216	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT630215	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT615955	hsa-miR-1470	HITS-CLIP	23824327
MIRT615954	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT615953	hsa-miR-5193	HITS-CLIP	23824327
MIRT615952	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT615951	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT615950	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT615949	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT615948	hsa-miR-4469	HITS-CLIP	23824327
MIRT615947	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT615946	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT615945	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT615944	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT615943	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT615942	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT615941	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT615940	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT1379599	hsa-miR-1264	CLIP-seq
MIRT1379600	hsa-miR-1285	CLIP-seq
MIRT1379601	hsa-miR-182	CLIP-seq
MIRT1379602	hsa-miR-199a-3p	CLIP-seq
MIRT1379603	hsa-miR-199b-3p	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT1379605	hsa-miR-2110	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT1379611	hsa-miR-31	CLIP-seq
MIRT1379612	hsa-miR-3129-5p	CLIP-seq
MIRT1379613	hsa-miR-3147	CLIP-seq
MIRT1379614	hsa-miR-3150a-3p	CLIP-seq
MIRT1379615	hsa-miR-3175	CLIP-seq
MIRT1379616	hsa-miR-326	CLIP-seq
MIRT1379617	hsa-miR-330-5p	CLIP-seq
MIRT1379618	hsa-miR-335	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT1379620	hsa-miR-3614-5p	CLIP-seq
MIRT1379621	hsa-miR-3647-3p	CLIP-seq
MIRT1379622	hsa-miR-369-3p	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT1379625	hsa-miR-374a	CLIP-seq
MIRT1379626	hsa-miR-374b	CLIP-seq
MIRT1379627	hsa-miR-378g	CLIP-seq
MIRT1379628	hsa-miR-4274	CLIP-seq
MIRT1379629	hsa-miR-4314	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT1379631	hsa-miR-433	CLIP-seq
MIRT1379632	hsa-miR-4425	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT1379634	hsa-miR-4486	CLIP-seq
MIRT1379635	hsa-miR-4490	CLIP-seq
MIRT1379636	hsa-miR-4519	CLIP-seq
MIRT1379637	hsa-miR-4640-5p	CLIP-seq
MIRT1379638	hsa-miR-4670-3p	CLIP-seq
MIRT1379639	hsa-miR-4687-5p	CLIP-seq
MIRT1379640	hsa-miR-4690-3p	CLIP-seq
MIRT1379641	hsa-miR-4694-3p	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379643	hsa-miR-4726-5p	CLIP-seq
MIRT1379644	hsa-miR-4728-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT1379647	hsa-miR-4781-3p	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT1379650	hsa-miR-512-5p	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379656	hsa-miR-548ac	CLIP-seq
MIRT1379657	hsa-miR-548d-3p	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT1379659	hsa-miR-548z	CLIP-seq
MIRT1379660	hsa-miR-615-5p	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT1379662	hsa-miR-936	CLIP-seq
MIRT1379663	hsa-miR-939	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT2113397	hsa-miR-124	CLIP-seq
MIRT2113398	hsa-miR-1253	CLIP-seq
MIRT2113399	hsa-miR-1255a	CLIP-seq
MIRT2113400	hsa-miR-1255b	CLIP-seq
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT1379599	hsa-miR-1264	CLIP-seq
MIRT1379600	hsa-miR-1285	CLIP-seq
MIRT2113401	hsa-miR-146b-3p	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT2113402	hsa-miR-3151	CLIP-seq
MIRT2113403	hsa-miR-3173-5p	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT2113404	hsa-miR-3616-3p	CLIP-seq
MIRT1379621	hsa-miR-3647-3p	CLIP-seq
MIRT2113405	hsa-miR-3692	CLIP-seq
MIRT2113406	hsa-miR-3714	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT1379627	hsa-miR-378g	CLIP-seq
MIRT2113407	hsa-miR-3910	CLIP-seq
MIRT2113408	hsa-miR-4278	CLIP-seq
MIRT2113409	hsa-miR-4289	CLIP-seq
MIRT1379629	hsa-miR-4314	CLIP-seq
MIRT2113410	hsa-miR-4318	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT2113411	hsa-miR-4324	CLIP-seq
MIRT1379631	hsa-miR-433	CLIP-seq
MIRT2113412	hsa-miR-4436b-3p	CLIP-seq
MIRT2113413	hsa-miR-4447	CLIP-seq
MIRT2113414	hsa-miR-4450	CLIP-seq
MIRT2113415	hsa-miR-4472	CLIP-seq
MIRT2113416	hsa-miR-4477b	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT1379634	hsa-miR-4486	CLIP-seq
MIRT1379637	hsa-miR-4640-5p	CLIP-seq
MIRT2113417	hsa-miR-4652-3p	CLIP-seq
MIRT2113418	hsa-miR-4721	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379643	hsa-miR-4726-5p	CLIP-seq
MIRT2113419	hsa-miR-4733-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT2113420	hsa-miR-4799-5p	CLIP-seq
MIRT2113421	hsa-miR-491-5p	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT2113422	hsa-miR-506	CLIP-seq
MIRT2113423	hsa-miR-508-3p	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT2113424	hsa-miR-874	CLIP-seq
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT2336438	hsa-miR-1294	CLIP-seq
MIRT2336439	hsa-miR-1343	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT1379616	hsa-miR-326	CLIP-seq
MIRT1379617	hsa-miR-330-5p	CLIP-seq
MIRT1379618	hsa-miR-335	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT2336440	hsa-miR-3619-3p	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT2336441	hsa-miR-3973	CLIP-seq
MIRT2113408	hsa-miR-4278	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT1379631	hsa-miR-433	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT2336442	hsa-miR-4710	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT2336443	hsa-miR-4763-5p	CLIP-seq
MIRT2336444	hsa-miR-4792	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT2336445	hsa-miR-513b	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT2336446	hsa-miR-593	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT2336447	hsa-miR-654-3p	CLIP-seq
MIRT2336448	hsa-miR-767-3p	CLIP-seq
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT1379606	hsa-miR-302a	CLIP-seq
MIRT1379607	hsa-miR-302b	CLIP-seq
MIRT1379608	hsa-miR-302c	CLIP-seq
MIRT1379609	hsa-miR-302d	CLIP-seq
MIRT1379610	hsa-miR-302e	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT1379623	hsa-miR-372	CLIP-seq
MIRT1379624	hsa-miR-373	CLIP-seq
MIRT2394953	hsa-miR-4299	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT1379649	hsa-miR-512-3p	CLIP-seq
MIRT1379651	hsa-miR-520a-3p	CLIP-seq
MIRT1379652	hsa-miR-520b	CLIP-seq
MIRT1379653	hsa-miR-520c-3p	CLIP-seq
MIRT1379654	hsa-miR-520d-3p	CLIP-seq
MIRT1379655	hsa-miR-520e	CLIP-seq
MIRT1379658	hsa-miR-548g	CLIP-seq
MIRT1379661	hsa-miR-628-5p	CLIP-seq
MIRT2630246	hsa-miR-103b	CLIP-seq
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT1379599	hsa-miR-1264	CLIP-seq
MIRT1379600	hsa-miR-1285	CLIP-seq
MIRT2630247	hsa-miR-129-5p	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT2630248	hsa-miR-299-5p	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT2630249	hsa-miR-3620	CLIP-seq
MIRT1379621	hsa-miR-3647-3p	CLIP-seq
MIRT1379627	hsa-miR-378g	CLIP-seq
MIRT2336441	hsa-miR-3973	CLIP-seq
MIRT1379629	hsa-miR-4314	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT1379631	hsa-miR-433	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT2630250	hsa-miR-4484	CLIP-seq
MIRT1379634	hsa-miR-4486	CLIP-seq
MIRT1379637	hsa-miR-4640-5p	CLIP-seq
MIRT2630251	hsa-miR-4662a-5p	CLIP-seq
MIRT1379638	hsa-miR-4670-3p	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379643	hsa-miR-4726-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT2630252	hsa-miR-509-3p	CLIP-seq
MIRT2630253	hsa-miR-526b	CLIP-seq
MIRT2630254	hsa-miR-548a-5p	CLIP-seq
MIRT2630255	hsa-miR-548ab	CLIP-seq
MIRT2630256	hsa-miR-548ak	CLIP-seq
MIRT2630257	hsa-miR-548an	CLIP-seq
MIRT2630258	hsa-miR-548b-5p	CLIP-seq
MIRT2630259	hsa-miR-548c-3p	CLIP-seq
MIRT2630260	hsa-miR-548c-5p	CLIP-seq
MIRT2630261	hsa-miR-548d-5p	CLIP-seq
MIRT2630262	hsa-miR-548h	CLIP-seq
MIRT2630263	hsa-miR-548i	CLIP-seq
MIRT2630264	hsa-miR-548j	CLIP-seq
MIRT2630265	hsa-miR-548w	CLIP-seq
MIRT2630266	hsa-miR-548y	CLIP-seq
MIRT2630267	hsa-miR-559	CLIP-seq
MIRT2630268	hsa-miR-579	CLIP-seq
MIRT2630246	hsa-miR-103b	CLIP-seq
MIRT1379597	hsa-miR-125a-5p	CLIP-seq
MIRT1379598	hsa-miR-125b	CLIP-seq
MIRT1379599	hsa-miR-1264	CLIP-seq
MIRT1379600	hsa-miR-1285	CLIP-seq
MIRT2630247	hsa-miR-129-5p	CLIP-seq
MIRT1379604	hsa-miR-205	CLIP-seq
MIRT1379619	hsa-miR-3614-3p	CLIP-seq
MIRT2630249	hsa-miR-3620	CLIP-seq
MIRT1379621	hsa-miR-3647-3p	CLIP-seq
MIRT1379627	hsa-miR-378g	CLIP-seq
MIRT2336441	hsa-miR-3973	CLIP-seq
MIRT1379629	hsa-miR-4314	CLIP-seq
MIRT1379630	hsa-miR-4319	CLIP-seq
MIRT1379631	hsa-miR-433	CLIP-seq
MIRT1379633	hsa-miR-4481	CLIP-seq
MIRT2630250	hsa-miR-4484	CLIP-seq
MIRT1379634	hsa-miR-4486	CLIP-seq
MIRT1379637	hsa-miR-4640-5p	CLIP-seq
MIRT2630251	hsa-miR-4662a-5p	CLIP-seq
MIRT1379638	hsa-miR-4670-3p	CLIP-seq
MIRT1379642	hsa-miR-4725-5p	CLIP-seq
MIRT1379643	hsa-miR-4726-5p	CLIP-seq
MIRT1379645	hsa-miR-4745-5p	CLIP-seq
MIRT1379646	hsa-miR-4758-5p	CLIP-seq
MIRT1379648	hsa-miR-504	CLIP-seq
MIRT2630253	hsa-miR-526b	CLIP-seq
MIRT2630254	hsa-miR-548a-5p	CLIP-seq
MIRT2630255	hsa-miR-548ab	CLIP-seq
MIRT2630256	hsa-miR-548ak	CLIP-seq
MIRT2630257	hsa-miR-548an	CLIP-seq
MIRT2630258	hsa-miR-548b-5p	CLIP-seq
MIRT2630260	hsa-miR-548c-5p	CLIP-seq
MIRT2630261	hsa-miR-548d-5p	CLIP-seq
MIRT2630262	hsa-miR-548h	CLIP-seq
MIRT2630263	hsa-miR-548i	CLIP-seq
MIRT2630264	hsa-miR-548j	CLIP-seq
MIRT2630265	hsa-miR-548w	CLIP-seq
MIRT2630266	hsa-miR-548y	CLIP-seq
MIRT2630267	hsa-miR-559	CLIP-seq

Show/Hide all (45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000721	Function	(R,R)-butanediol dehydrogenase activity	IEA
GO:0003939	Function	L-iditol 2-dehydrogenase (NAD+) activity	IBA
GO:0003939	Function	L-iditol 2-dehydrogenase (NAD+) activity	IDA	3365415, 6870831, 8487505
GO:0003939	Function	L-iditol 2-dehydrogenase (NAD+) activity	IEA
GO:0003939	Function	L-iditol 2-dehydrogenase (NAD+) activity	IMP	32367058
GO:0003939	Function	L-iditol 2-dehydrogenase (NAD+) activity	ISS
GO:0004022	Function	Alcohol dehydrogenase (NAD+) activity	IEA
GO:0005615	Component	Extracellular space	TAS	6177277
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005929	Component	Cilium	IEA
GO:0006006	Process	Glucose metabolic process	TAS	14965227
GO:0006060	Process	Sorbitol metabolic process	IEA
GO:0006062	Process	Sorbitol catabolic process	IBA
GO:0006062	Process	Sorbitol catabolic process	IDA	3365415, 6870831, 8487505, 12962626
GO:0006062	Process	Sorbitol catabolic process	IMP	32367058
GO:0008270	Function	Zinc ion binding	IDA	12962626
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	ISS
GO:0016020	Component	Membrane	IDA	8487505
GO:0016020	Component	Membrane	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016616	Function	Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
GO:0019640	Process	D-glucuronate catabolic process to D-xylulose 5-phosphate	IEA
GO:0030246	Function	Carbohydrate binding	NAS	12962626
GO:0030317	Process	Flagellated sperm motility	IEA
GO:0030317	Process	Flagellated sperm motility	ISS
GO:0030317	Process	Flagellated sperm motility	NAS	16278369
GO:0031514	Component	Motile cilium	IEA
GO:0031514	Component	Motile cilium	ISS
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0042802	Function	Identical protein binding	IPI	16189514, 21516116, 31515488, 32296183
GO:0042995	Component	Cell projection	IEA
GO:0046370	Process	Fructose biosynthetic process	IDA	3365415, 6870831, 8487505
GO:0046370	Process	Fructose biosynthetic process	IEA
GO:0046526	Function	D-xylulose reductase activity	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0047833	Function	D-sorbitol dehydrogenase (acceptor) activity	IEA
GO:0050255	Function	Ribitol 2-dehydrogenase (NAD+) activity	IEA
GO:0051160	Process	Xylitol catabolic process	IDA	8487505
GO:0051164	Process	Xylitol metabolic process	IDA	3365415
GO:0051287	Function	NAD binding	IDA	12962626
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0070062	Component	Extracellular exosome	IDA	21557262

MIM	HGNC	e!Ensembl
182500	11184	ENSG00000140263

Q00796

Protein name

Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9)

Protein function

Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), L-threitol, xylitol and ribitol as substrates, leading to the C2-oxidized products D-fructose

PDB

1PL6 , 1PL7 , 1PL8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08240	ADH_N	32 → 143	Alcohol dehydrogenase GroES-like domain	Domain
PF00107	ADH_zinc_N	183 → 313	Zinc-binding dehydrogenase	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in liver (PubMed:3365415). Expressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:16278369, ECO:0000269|PubMed:19423711, ECO:0000

Sequence

MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC
ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG
AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL
GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY
CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP

Sequence length

357

Interactions

View interactions

	KEGG		Reactome
	Pentose and glucuronate interconversions Fructose and mannose metabolism Metabolic pathways		Fructose biosynthesis Formation of xylulose-5-phosphate

Show/Hide Causal Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Idiopathic environmental intolerance	Likely pathogenic; Pathogenic	rs55901542	RCV002468945
Neuromuscular disease	Likely pathogenic; Pathogenic	rs55901542	RCV004017799
Neuronopathy, distal hereditary motor, autosomal recessive 8	Likely pathogenic; Pathogenic	rs925016698, rs746985755, rs765674420, rs2504718500, rs2504702178, rs1267443415, rs55901542, rs145813597	RCV002471542 RCV003152297 RCV003152298 RCV003152299 RCV003881721 RCV001194462 RCV001194463 RCV003152760

Show/Hide Unknown Diseases (12)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs71480278	RCV005919790
Cervical cancer	Benign	rs71480278, rs2229656	RCV005919792 RCV005903701
Cholangiocarcinoma	Benign	rs2229656	RCV005903707
Clear cell carcinoma of kidney	Benign	rs2229656	RCV005903702
Colon adenocarcinoma	Benign	rs2229656	RCV005903698
Hepatocellular carcinoma	Benign	rs2229656	RCV005903699
Malignant tumor of esophagus	Benign	rs71480278, rs2229656	RCV005919791 RCV005903700
Ovarian serous cystadenocarcinoma	Benign	rs71480278, rs2229656	RCV005919794 RCV005903704
Sarcoma	Benign	rs71480278, rs2229656	RCV005919793 RCV005903703
Thymoma	Benign	rs2229656	RCV005903706
Uterine carcinosarcoma	Benign	rs2229656	RCV005903705
Uterine corpus endometrial carcinoma	Benign	rs71480278, rs2229656	RCV005919795 RCV005903708

Show/Hide Text Mining Associations (18)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenoma	Stimulate	24567419
Carcinoma Hepatocellular	Associate	31272500
Celiac Disease	Associate	27650971
Charcot Marie Tooth Disease	Associate	33314640
Charcot Marie Tooth disease Type 2B	Associate	33314640
Colorectal Neoplasms	Associate	24567419
Coronary Artery Disease	Associate	36743388
Diabetes Mellitus Type 2	Stimulate	36749929
Diabetic Neuropathies	Associate	35436891
Diabetic Retinopathy	Associate	31539366
Distal Hereditary Motor Neuropathy Type II	Associate	35436891
Genetic Diseases Inborn	Associate	35436891
Neoplasms	Stimulate	24567419
Neoplastic Syndromes Hereditary	Associate	33875678, 35436891
Nephrosclerosis	Associate	29328390
Nervous System Diseases	Associate	33875678
Neurodegenerative Diseases	Associate	37014713
Pleural Effusion Malignant	Associate	20884743

SORD (sorbitol dehydrogenase)