Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
66036
Gene name Gene Name - the full gene name approved by the HGNC.
Myotubularin related protein 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MTMR9
Synonyms (NCBI Gene) Gene synonyms aliases
C8orf9, LIP-STYX, MTMR8
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p23.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SE
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020334 hsa-miR-130b-3p Sequencing 20371350
MIRT025530 hsa-miR-34a-5p Sequencing 20371350
MIRT026001 hsa-miR-148a-3p Sequencing 20371350
MIRT030977 hsa-miR-21-5p Microarray 18591254
MIRT706537 hsa-miR-106a-5p HITS-CLIP 22927820
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004438 Function Phosphatidylinositol-3-phosphatase activity IBA 21873635
GO:0005515 Function Protein binding IPI 12890864, 16189514, 19447967, 21516116, 22647598, 25416956, 28514442, 29892012, 31515488, 32296183
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005737 Component Cytoplasm IDA 16787938
GO:0005783 Component Endoplasmic reticulum IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
606260 14596 ENSG00000104643
Protein
UniProt ID Q96QG7
Protein name Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9)
Protein function Acts as an adapter for myotubularin-related phosphatases (PubMed:19038970, PubMed:22647598). Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate and MTMR6 binding affinity for phosphor
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06602 Myotub-related 108 446 Myotubularin-like phosphatase domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in many tissues. {ECO:0000269|PubMed:11472061}.
Sequence
Sequence length 549
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Synthesis of PIPs at the plasma membrane
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)
17855449
Unknown
Disease term Disease name Evidence References Source
Neuroticism Neuroticism GWAS
Hypertension Hypertension GWAS
Prostate cancer Prostate cancer Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 39524444
Carcinoma Hepatocellular Associate 36965814
Metabolic Syndrome Associate 21796137