Gene Gene information from NCBI Gene database.
Entrez ID 66036
Gene name Myotubularin related protein 9
Gene symbol MTMR9
Synonyms (NCBI Gene)
C8orf9LIP-STYXMTMR8
Chromosome 8
Chromosome location 8p23.1
Summary This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SE
miRNA miRNA information provided by mirtarbase database.
864
miRTarBase ID miRNA Experiments Reference
MIRT020334 hsa-miR-130b-3p Sequencing 20371350
MIRT025530 hsa-miR-34a-5p Sequencing 20371350
MIRT026001 hsa-miR-148a-3p Sequencing 20371350
MIRT030977 hsa-miR-21-5p Microarray 18591254
MIRT706537 hsa-miR-106a-5p HITS-CLIP 22927820
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 12890864, 16189514, 19447967, 21516116, 22647598, 25416956, 27880917, 28514442, 29892012, 31515488, 32296183, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 16787938
GO:0005737 Component Cytoplasm IEA
GO:0005783 Component Endoplasmic reticulum IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606260 14596 ENSG00000104643
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96QG7
Protein name Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9)
Protein function Acts as an adapter for myotubularin-related phosphatases (PubMed:19038970, PubMed:22647598). Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate and MTMR6 binding affinity for phosphor
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06602 Myotub-related 108 446 Myotubularin-like phosphatase domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in many tissues. {ECO:0000269|PubMed:11472061}.
Sequence
Sequence length 549
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Synthesis of PIPs at the plasma membrane
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Clear cell carcinoma of kidney Uncertain significance rs759875697 RCV005930960
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Breast Neoplasms Associate 39524444
Carcinoma Hepatocellular Associate 36965814
Metabolic Syndrome Associate 21796137