Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	65991
Gene name Gene Name - the full gene name approved by the HGNC.	FUN14 domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FUNDC2
Synonyms (NCBI Gene) Gene synonyms aliases	DC44, HCBP6, HCC3, PD03104
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xq28

Show/Hide all(263)

miRTarBase ID	miRNA	Experiments	Reference
MIRT003098	hsa-miR-122-5p	Luciferase reporter assay, qRT-PCR	19296470
MIRT003098	hsa-miR-122-5p	Luciferase reporter assay, qRT-PCR	19296470
MIRT044913	hsa-miR-186-5p	CLASH	23622248
MIRT042745	hsa-miR-339-5p	CLASH	23622248
MIRT041249	hsa-miR-193b-3p	CLASH	23622248
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT528666	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT528665	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT528664	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT528663	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT528662	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT528661	hsa-miR-3174	PAR-CLIP	22012620
MIRT528660	hsa-miR-4682	PAR-CLIP	22012620
MIRT528659	hsa-miR-633	PAR-CLIP	22012620
MIRT528658	hsa-miR-921	PAR-CLIP	22012620
MIRT528657	hsa-miR-4303	PAR-CLIP	22012620
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT619228	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT619227	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT619226	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT619225	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT619224	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT619223	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT619222	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619221	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT619220	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT619219	hsa-miR-2053	HITS-CLIP	23824327
MIRT528666	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT528665	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT528664	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT528663	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT528662	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT528661	hsa-miR-3174	PAR-CLIP	22012620
MIRT528660	hsa-miR-4682	PAR-CLIP	22012620
MIRT528659	hsa-miR-633	PAR-CLIP	22012620
MIRT528658	hsa-miR-921	PAR-CLIP	22012620
MIRT528657	hsa-miR-4303	PAR-CLIP	22012620
MIRT1006178	hsa-miR-1227	CLIP-seq
MIRT1006179	hsa-miR-1236	CLIP-seq
MIRT1006180	hsa-miR-1253	CLIP-seq
MIRT1006181	hsa-miR-127-5p	CLIP-seq
MIRT1006182	hsa-miR-1303	CLIP-seq
MIRT1006183	hsa-miR-196a	CLIP-seq
MIRT1006184	hsa-miR-196b	CLIP-seq
MIRT1006185	hsa-miR-3064-3p	CLIP-seq
MIRT1006186	hsa-miR-3123	CLIP-seq
MIRT1006187	hsa-miR-3126-5p	CLIP-seq
MIRT1006188	hsa-miR-3182	CLIP-seq
MIRT1006189	hsa-miR-3622b-5p	CLIP-seq
MIRT1006190	hsa-miR-3925-5p	CLIP-seq
MIRT1006191	hsa-miR-4330	CLIP-seq
MIRT1006192	hsa-miR-4434	CLIP-seq
MIRT1006193	hsa-miR-4516	CLIP-seq
MIRT1006194	hsa-miR-4530	CLIP-seq
MIRT1006195	hsa-miR-4715-3p	CLIP-seq
MIRT1006196	hsa-miR-4727-5p	CLIP-seq
MIRT1006197	hsa-miR-4761-5p	CLIP-seq
MIRT1006198	hsa-miR-4769-3p	CLIP-seq
MIRT1006199	hsa-miR-4779	CLIP-seq
MIRT1006200	hsa-miR-4786-3p	CLIP-seq
MIRT1006201	hsa-miR-593	CLIP-seq
MIRT1006202	hsa-miR-634	CLIP-seq
MIRT1006203	hsa-miR-765	CLIP-seq
MIRT1006204	hsa-miR-888	CLIP-seq
MIRT1006205	hsa-miR-922	CLIP-seq
MIRT1920452	hsa-miR-142-5p	CLIP-seq
MIRT1920453	hsa-miR-340	CLIP-seq
MIRT1920454	hsa-miR-3671	CLIP-seq
MIRT1920455	hsa-miR-4272	CLIP-seq
MIRT1920456	hsa-miR-4528	CLIP-seq
MIRT1920457	hsa-miR-607	CLIP-seq
MIRT1920452	hsa-miR-142-5p	CLIP-seq
MIRT1920453	hsa-miR-340	CLIP-seq
MIRT1920454	hsa-miR-3671	CLIP-seq
MIRT1920455	hsa-miR-4272	CLIP-seq
MIRT1920456	hsa-miR-4528	CLIP-seq
MIRT1920457	hsa-miR-607	CLIP-seq
MIRT1920452	hsa-miR-142-5p	CLIP-seq
MIRT1920453	hsa-miR-340	CLIP-seq
MIRT1920454	hsa-miR-3671	CLIP-seq
MIRT1920455	hsa-miR-4272	CLIP-seq
MIRT1920456	hsa-miR-4528	CLIP-seq
MIRT1920457	hsa-miR-607	CLIP-seq
MIRT1998146	hsa-miR-106a	CLIP-seq
MIRT1998147	hsa-miR-106b	CLIP-seq
MIRT1998148	hsa-miR-1184	CLIP-seq
MIRT1998149	hsa-miR-1302	CLIP-seq
MIRT1006182	hsa-miR-1303	CLIP-seq
MIRT1998150	hsa-miR-17	CLIP-seq
MIRT1998151	hsa-miR-2054	CLIP-seq
MIRT1998152	hsa-miR-20a	CLIP-seq
MIRT1998153	hsa-miR-20b	CLIP-seq
MIRT1998154	hsa-miR-224	CLIP-seq
MIRT1998155	hsa-miR-3122	CLIP-seq
MIRT1006186	hsa-miR-3123	CLIP-seq
MIRT1998156	hsa-miR-3148	CLIP-seq
MIRT1998157	hsa-miR-3157-5p	CLIP-seq
MIRT1998158	hsa-miR-3609	CLIP-seq
MIRT1998159	hsa-miR-377	CLIP-seq
MIRT1998160	hsa-miR-3913-5p	CLIP-seq
MIRT1006190	hsa-miR-3925-5p	CLIP-seq
MIRT1998161	hsa-miR-4298	CLIP-seq
MIRT1006191	hsa-miR-4330	CLIP-seq
MIRT1998162	hsa-miR-4661-3p	CLIP-seq
MIRT1998163	hsa-miR-4691-3p	CLIP-seq
MIRT1998164	hsa-miR-4691-5p	CLIP-seq
MIRT1006200	hsa-miR-4786-3p	CLIP-seq
MIRT1998165	hsa-miR-4793-5p	CLIP-seq
MIRT1998166	hsa-miR-4796-3p	CLIP-seq
MIRT1998167	hsa-miR-519d	CLIP-seq
MIRT1998168	hsa-miR-548ah	CLIP-seq
MIRT1998169	hsa-miR-555	CLIP-seq
MIRT1998170	hsa-miR-604	CLIP-seq
MIRT1998171	hsa-miR-643	CLIP-seq
MIRT1998172	hsa-miR-647	CLIP-seq
MIRT1998173	hsa-miR-93	CLIP-seq
MIRT1006180	hsa-miR-1253	CLIP-seq
MIRT1006187	hsa-miR-3126-5p	CLIP-seq
MIRT2231812	hsa-miR-3185	CLIP-seq
MIRT1006189	hsa-miR-3622b-5p	CLIP-seq
MIRT2231813	hsa-miR-3910	CLIP-seq
MIRT2231814	hsa-miR-4277	CLIP-seq
MIRT1006192	hsa-miR-4434	CLIP-seq
MIRT1006193	hsa-miR-4516	CLIP-seq
MIRT1006199	hsa-miR-4779	CLIP-seq
MIRT2231815	hsa-miR-548aa	CLIP-seq
MIRT2231816	hsa-miR-548ac	CLIP-seq
MIRT2231817	hsa-miR-548d-3p	CLIP-seq
MIRT2231818	hsa-miR-548z	CLIP-seq
MIRT2231819	hsa-miR-587	CLIP-seq
MIRT2231820	hsa-miR-630	CLIP-seq
MIRT1006203	hsa-miR-765	CLIP-seq
MIRT2231821	hsa-miR-873	CLIP-seq
MIRT2388243	hsa-miR-1272	CLIP-seq
MIRT2388244	hsa-miR-1322	CLIP-seq
MIRT2535829	hsa-miR-1207-5p	CLIP-seq
MIRT2535830	hsa-miR-122	CLIP-seq
MIRT1006178	hsa-miR-1227	CLIP-seq
MIRT1006180	hsa-miR-1253	CLIP-seq
MIRT2388243	hsa-miR-1272	CLIP-seq
MIRT1006181	hsa-miR-127-5p	CLIP-seq
MIRT1006182	hsa-miR-1303	CLIP-seq
MIRT2388244	hsa-miR-1322	CLIP-seq
MIRT1006183	hsa-miR-196a	CLIP-seq
MIRT1006184	hsa-miR-196b	CLIP-seq
MIRT2535831	hsa-miR-2964a-5p	CLIP-seq
MIRT1006185	hsa-miR-3064-3p	CLIP-seq
MIRT1006186	hsa-miR-3123	CLIP-seq
MIRT1006187	hsa-miR-3126-5p	CLIP-seq
MIRT2535832	hsa-miR-3134	CLIP-seq
MIRT2231812	hsa-miR-3185	CLIP-seq
MIRT1006189	hsa-miR-3622b-5p	CLIP-seq
MIRT2231813	hsa-miR-3910	CLIP-seq
MIRT1006190	hsa-miR-3925-5p	CLIP-seq
MIRT2535833	hsa-miR-4280	CLIP-seq
MIRT1006191	hsa-miR-4330	CLIP-seq
MIRT1006192	hsa-miR-4434	CLIP-seq
MIRT1006193	hsa-miR-4516	CLIP-seq
MIRT1006194	hsa-miR-4530	CLIP-seq
MIRT2535834	hsa-miR-4534	CLIP-seq
MIRT2535835	hsa-miR-4659a-5p	CLIP-seq
MIRT2535836	hsa-miR-4659b-5p	CLIP-seq
MIRT1006195	hsa-miR-4715-3p	CLIP-seq
MIRT2535837	hsa-miR-4732-5p	CLIP-seq
MIRT2535838	hsa-miR-4736	CLIP-seq
MIRT1006197	hsa-miR-4761-5p	CLIP-seq
MIRT2535839	hsa-miR-4763-3p	CLIP-seq
MIRT2535840	hsa-miR-4776-3p	CLIP-seq
MIRT1006199	hsa-miR-4779	CLIP-seq
MIRT1006200	hsa-miR-4786-3p	CLIP-seq
MIRT2535841	hsa-miR-485-5p	CLIP-seq
MIRT1006202	hsa-miR-634	CLIP-seq
MIRT2535842	hsa-miR-676	CLIP-seq
MIRT1006203	hsa-miR-765	CLIP-seq
MIRT1006205	hsa-miR-922	CLIP-seq
MIRT2535829	hsa-miR-1207-5p	CLIP-seq
MIRT2535830	hsa-miR-122	CLIP-seq
MIRT1006178	hsa-miR-1227	CLIP-seq
MIRT1006180	hsa-miR-1253	CLIP-seq
MIRT2388243	hsa-miR-1272	CLIP-seq
MIRT1006181	hsa-miR-127-5p	CLIP-seq
MIRT1006182	hsa-miR-1303	CLIP-seq
MIRT2388244	hsa-miR-1322	CLIP-seq
MIRT1006183	hsa-miR-196a	CLIP-seq
MIRT1006184	hsa-miR-196b	CLIP-seq
MIRT2535831	hsa-miR-2964a-5p	CLIP-seq
MIRT1006185	hsa-miR-3064-3p	CLIP-seq
MIRT1006186	hsa-miR-3123	CLIP-seq
MIRT1006187	hsa-miR-3126-5p	CLIP-seq
MIRT2535832	hsa-miR-3134	CLIP-seq
MIRT2231812	hsa-miR-3185	CLIP-seq
MIRT1006189	hsa-miR-3622b-5p	CLIP-seq
MIRT2231813	hsa-miR-3910	CLIP-seq
MIRT1006190	hsa-miR-3925-5p	CLIP-seq
MIRT2535833	hsa-miR-4280	CLIP-seq
MIRT1006191	hsa-miR-4330	CLIP-seq
MIRT1006192	hsa-miR-4434	CLIP-seq
MIRT1006193	hsa-miR-4516	CLIP-seq
MIRT1006194	hsa-miR-4530	CLIP-seq
MIRT2535834	hsa-miR-4534	CLIP-seq
MIRT2535835	hsa-miR-4659a-5p	CLIP-seq
MIRT2535836	hsa-miR-4659b-5p	CLIP-seq
MIRT1006195	hsa-miR-4715-3p	CLIP-seq
MIRT2535837	hsa-miR-4732-5p	CLIP-seq
MIRT2535838	hsa-miR-4736	CLIP-seq
MIRT1006197	hsa-miR-4761-5p	CLIP-seq
MIRT2535839	hsa-miR-4763-3p	CLIP-seq
MIRT2535840	hsa-miR-4776-3p	CLIP-seq
MIRT1006199	hsa-miR-4779	CLIP-seq
MIRT1006200	hsa-miR-4786-3p	CLIP-seq
MIRT2535841	hsa-miR-485-5p	CLIP-seq
MIRT1006202	hsa-miR-634	CLIP-seq
MIRT2535842	hsa-miR-676	CLIP-seq
MIRT1006203	hsa-miR-765	CLIP-seq
MIRT1006205	hsa-miR-922	CLIP-seq

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000422	Process	Autophagy of mitochondrion	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005739	Component	Mitochondrion	HDA	20833797
GO:0005739	Component	Mitochondrion	IDA
GO:0031307	Component	Integral component of mitochondrial outer membrane	IBA	21873635

MIM	HGNC	e!Ensembl
301042	24925	ENSG00000165775

Protein

UniProt ID

Q9BWH2

Protein name

FUN14 domain-containing protein 2 (Cervical cancer proto-oncogene 3 protein) (HCC-3) (Hepatitis C virus core-binding protein 6)

Protein function

Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04930	FUN14	87 → 187	FUN14 family	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in platelets (at protein level). {ECO:0000269|PubMed:30576423}.

Sequence

METSAPRAGSQVVATTARHSAAYRADPLRVSSRDKLTEMAASSQGNFEGNFESLDLAEFA
KKQPWWRKLFGQESGPSAEKYSVATQLFIGGVTGWCTGFIFQKVGKLAATAVGGGFFLLQ
LANHTGYIKVDWQRVEKDMKKAKEQLKIRKSNQIPTEVRSKAEEVVSFVKKNVLVTGGFF
GGFLLGMAS

Sequence length

189

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Ischemic stroke	Ischemic stroke		26908601	ClinVar

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Coronary Artery Disease	Associate	26908601
Hypoxia	Associate	34105393
Hypoxia Brain	Associate	34105393
Mitochondrial Diseases	Associate	34105393
Nerve Degeneration	Associate	34105393
Thrombosis	Associate	26908601

FUNDC2 (FUN14 domain containing 2)