Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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65975
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Serine/threonine kinase 33 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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STK33 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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SPGF93 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
SPGF93 |
Chromosome
Chromosome number
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11 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
11p15.4 |
UniProt ID |
Q9BYT3
|
Protein name |
Serine/threonine-protein kinase 33 (EC 2.7.11.1) |
Protein function |
Serine/threonine protein kinase required for spermatid differentiation and male fertility (PubMed:37146716, PubMed:38781365). Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 a |
PDB |
8VF6
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00069
|
Pkinase |
116 → 381 |
Protein kinase domain |
Domain |
|
Tissue specificity |
TISSUE SPECIFICITY: Highly expressed in testis, fetal lung and heart, followed by pituitary gland, kidney, interventricular septum, pancreas, heart, trachea, thyroid gland and uterus. Weak hybridization signals were observed in the following tissues: amyg |
Sequence |
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Sequence length |
514 |
Interactions |
View interactions
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Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Lung carcinoma |
Small cell carcinoma of lung, Large cell carcinoma of lung |
rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193 View all (44 more) |
28604730 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Restless Legs Syndrome |
Restless Legs Syndrome |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Moyamoya Disease |
Moyamoya Disease |
|
|
GWAS |
|
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