Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
64689
Gene name Gene Name - the full gene name approved by the HGNC.
Golgi reassembly stacking protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GORASP1
Synonyms (NCBI Gene) Gene synonyms aliases
GOLPH5, GRASP65, P65
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p22.2
Summary Summary of gene provided in NCBI Entrez Gene.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a c
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT639574 hsa-miR-3529-3p HITS-CLIP 23824327
MIRT639573 hsa-miR-4773 HITS-CLIP 23824327
MIRT639572 hsa-miR-516a-3p HITS-CLIP 23824327
MIRT639571 hsa-miR-516b-3p HITS-CLIP 23824327
MIRT639570 hsa-miR-7162-5p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0005515 Function Protein binding IPI 16489344, 18045989, 25416956, 26871637, 31515488, 32296183
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0005794 Component Golgi apparatus IDA 18045989
GO:0006487 Process Protein N-linked glycosylation IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
606867 16769 ENSG00000114745
Protein
UniProt ID Q9BQQ3
Protein name Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65)
Protein function Key structural protein of the Golgi apparatus (PubMed:33301566). The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (PubMed:33301566). Acting in concert with
PDB 4REY , 6G8T , 6G8W
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04495 GRASP55_65 1 91 GRASP55/65 PDZ-like domain Domain
PF04495 GRASP55_65 69 205 GRASP55/65 PDZ-like domain Domain
Sequence
MGLGVSAEQPAGGAEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLK
ANVEKPVK
LEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEP
SSPAALAGLRPYTDYVVGSDQILQESEDFFTLIESHEGKPLKLMVYNSKSDSCREVTVTP
NAAWGGEGSLGCGIGYGYLHRIPTQ
PPSYHKKPPGTPPPSALPLGAPPPDALPPGPTPED
SPSLETGSRQSDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQPPPPVQ
RVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSSSSHERGGEAT
WSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTEG
LDTGTEAEGLDSQAQISTTE
Sequence length 440
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Autophagy - animal   Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 22491060
Carcinoma Renal Cell Associate 24977159
Carcinoma Squamous Cell Associate 22491060
Neoplasm Metastasis Associate 22491060
Neoplasms Associate 22491060, 24977159, 31770410
Ovarian Neoplasms Associate 31770410