Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	64651
Gene name	Cysteine and serine rich nuclear protein 1
Gene symbol	CSRNP1
Synonyms (NCBI Gene)	AXUD1CSRNP-1FAM130BTAIP-3URAX1
Chromosome	3
Chromosome location	3p22.2
Summary	This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development

176

Show/Hide all (176)

miRTarBase ID	miRNA	Experiments
MIRT912918	hsa-miR-122	CLIP-seq
MIRT912919	hsa-miR-1229	CLIP-seq
MIRT912920	hsa-miR-1236	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912922	hsa-miR-1270	CLIP-seq
MIRT912923	hsa-miR-1271	CLIP-seq
MIRT912924	hsa-miR-1272	CLIP-seq
MIRT912925	hsa-miR-1322	CLIP-seq
MIRT912926	hsa-miR-146b-3p	CLIP-seq
MIRT912927	hsa-miR-183	CLIP-seq
MIRT912928	hsa-miR-3117-5p	CLIP-seq
MIRT912929	hsa-miR-3151	CLIP-seq
MIRT912930	hsa-miR-3153	CLIP-seq
MIRT912931	hsa-miR-3155	CLIP-seq
MIRT912932	hsa-miR-3155b	CLIP-seq
MIRT912933	hsa-miR-3157-5p	CLIP-seq
MIRT912934	hsa-miR-3193	CLIP-seq
MIRT912935	hsa-miR-339-5p	CLIP-seq
MIRT912936	hsa-miR-3617	CLIP-seq
MIRT912937	hsa-miR-3622a-3p	CLIP-seq
MIRT912938	hsa-miR-3622b-3p	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT912940	hsa-miR-4260	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT912942	hsa-miR-4283	CLIP-seq
MIRT912943	hsa-miR-4284	CLIP-seq
MIRT912944	hsa-miR-4421	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT912946	hsa-miR-4447	CLIP-seq
MIRT912947	hsa-miR-4455	CLIP-seq
MIRT912948	hsa-miR-4472	CLIP-seq
MIRT912949	hsa-miR-4489	CLIP-seq
MIRT912950	hsa-miR-4492	CLIP-seq
MIRT912951	hsa-miR-4498	CLIP-seq
MIRT912952	hsa-miR-4505	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT912954	hsa-miR-4645-5p	CLIP-seq
MIRT912955	hsa-miR-4646-5p	CLIP-seq
MIRT912956	hsa-miR-4668-5p	CLIP-seq
MIRT912957	hsa-miR-4673	CLIP-seq
MIRT912958	hsa-miR-4683	CLIP-seq
MIRT912959	hsa-miR-4688	CLIP-seq
MIRT912960	hsa-miR-4690-3p	CLIP-seq
MIRT912961	hsa-miR-4717-3p	CLIP-seq
MIRT912962	hsa-miR-4752	CLIP-seq
MIRT912963	hsa-miR-484	CLIP-seq
MIRT912964	hsa-miR-486-3p	CLIP-seq
MIRT912965	hsa-miR-491-5p	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq
MIRT912967	hsa-miR-574-5p	CLIP-seq
MIRT912968	hsa-miR-578	CLIP-seq
MIRT912969	hsa-miR-596	CLIP-seq
MIRT912970	hsa-miR-609	CLIP-seq
MIRT912971	hsa-miR-620	CLIP-seq
MIRT912972	hsa-miR-635	CLIP-seq
MIRT912973	hsa-miR-641	CLIP-seq
MIRT912974	hsa-miR-648	CLIP-seq
MIRT912975	hsa-miR-762	CLIP-seq
MIRT912976	hsa-miR-9	CLIP-seq
MIRT912977	hsa-miR-96	CLIP-seq
MIRT1970761	hsa-miR-1254	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912924	hsa-miR-1272	CLIP-seq
MIRT1970762	hsa-miR-1285	CLIP-seq
MIRT912925	hsa-miR-1322	CLIP-seq
MIRT1970763	hsa-miR-2861	CLIP-seq
MIRT1970764	hsa-miR-3116	CLIP-seq
MIRT912928	hsa-miR-3117-5p	CLIP-seq
MIRT1970765	hsa-miR-3122	CLIP-seq
MIRT1970766	hsa-miR-3163	CLIP-seq
MIRT1970767	hsa-miR-3187-5p	CLIP-seq
MIRT1970768	hsa-miR-326	CLIP-seq
MIRT1970769	hsa-miR-330-5p	CLIP-seq
MIRT1970770	hsa-miR-3622b-5p	CLIP-seq
MIRT1970771	hsa-miR-3664-3p	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT1970772	hsa-miR-3913-5p	CLIP-seq
MIRT1970773	hsa-miR-4253	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT1970774	hsa-miR-4433	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT1970775	hsa-miR-4459	CLIP-seq
MIRT1970776	hsa-miR-4484	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT1970777	hsa-miR-4667-5p	CLIP-seq
MIRT1970778	hsa-miR-4700-5p	CLIP-seq
MIRT1970779	hsa-miR-4766-3p	CLIP-seq
MIRT1970780	hsa-miR-4768-3p	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq
MIRT1970781	hsa-miR-548ac	CLIP-seq
MIRT1970782	hsa-miR-548ae	CLIP-seq
MIRT1970783	hsa-miR-548aj	CLIP-seq
MIRT1970784	hsa-miR-548am	CLIP-seq
MIRT1970785	hsa-miR-548an	CLIP-seq
MIRT1970786	hsa-miR-548d-3p	CLIP-seq
MIRT1970787	hsa-miR-548p	CLIP-seq
MIRT1970788	hsa-miR-548x	CLIP-seq
MIRT1970789	hsa-miR-548z	CLIP-seq
MIRT1970790	hsa-miR-612	CLIP-seq
MIRT1970791	hsa-miR-637	CLIP-seq
MIRT1970792	hsa-miR-663b	CLIP-seq
MIRT2206542	hsa-miR-1207-5p	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912924	hsa-miR-1272	CLIP-seq
MIRT912925	hsa-miR-1322	CLIP-seq
MIRT2206543	hsa-miR-1914	CLIP-seq
MIRT1970763	hsa-miR-2861	CLIP-seq
MIRT912928	hsa-miR-3117-5p	CLIP-seq
MIRT912929	hsa-miR-3151	CLIP-seq
MIRT2206544	hsa-miR-3168	CLIP-seq
MIRT912934	hsa-miR-3193	CLIP-seq
MIRT2206545	hsa-miR-331-3p	CLIP-seq
MIRT2206546	hsa-miR-3660	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT2206547	hsa-miR-4256	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT2206548	hsa-miR-4526	CLIP-seq
MIRT2206549	hsa-miR-4694-3p	CLIP-seq
MIRT2206550	hsa-miR-4763-3p	CLIP-seq
MIRT1970779	hsa-miR-4766-3p	CLIP-seq
MIRT2206551	hsa-miR-4795-5p	CLIP-seq
MIRT912964	hsa-miR-486-3p	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq
MIRT2206552	hsa-miR-519a	CLIP-seq
MIRT2206553	hsa-miR-519b-3p	CLIP-seq
MIRT2206554	hsa-miR-519c-3p	CLIP-seq
MIRT2206555	hsa-miR-539	CLIP-seq
MIRT1970787	hsa-miR-548p	CLIP-seq
MIRT912968	hsa-miR-578	CLIP-seq
MIRT912969	hsa-miR-596	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912924	hsa-miR-1272	CLIP-seq
MIRT912925	hsa-miR-1322	CLIP-seq
MIRT912928	hsa-miR-3117-5p	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT2386542	hsa-miR-371b-3p	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq
MIRT1970765	hsa-miR-3122	CLIP-seq
MIRT1970772	hsa-miR-3913-5p	CLIP-seq
MIRT1970776	hsa-miR-4484	CLIP-seq
MIRT1970785	hsa-miR-548an	CLIP-seq
MIRT1970792	hsa-miR-663b	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912924	hsa-miR-1272	CLIP-seq
MIRT912925	hsa-miR-1322	CLIP-seq
MIRT912928	hsa-miR-3117-5p	CLIP-seq
MIRT1970766	hsa-miR-3163	CLIP-seq
MIRT1970771	hsa-miR-3664-3p	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT1970774	hsa-miR-4433	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT1970775	hsa-miR-4459	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT1970779	hsa-miR-4766-3p	CLIP-seq
MIRT1970780	hsa-miR-4768-3p	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq
MIRT1970781	hsa-miR-548ac	CLIP-seq
MIRT1970782	hsa-miR-548ae	CLIP-seq
MIRT1970783	hsa-miR-548aj	CLIP-seq
MIRT1970784	hsa-miR-548am	CLIP-seq
MIRT1970786	hsa-miR-548d-3p	CLIP-seq
MIRT1970787	hsa-miR-548p	CLIP-seq
MIRT1970788	hsa-miR-548x	CLIP-seq
MIRT1970789	hsa-miR-548z	CLIP-seq
MIRT912921	hsa-miR-1266	CLIP-seq
MIRT912939	hsa-miR-3668	CLIP-seq
MIRT912941	hsa-miR-4270	CLIP-seq
MIRT912945	hsa-miR-4441	CLIP-seq
MIRT912953	hsa-miR-4518	CLIP-seq
MIRT912966	hsa-miR-510	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0003700	Function	DNA-binding transcription factor activity	ISS	17726538
GO:0005515	Function	Protein binding	IPI	22321011, 25416956, 28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS	17726538
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	NAS	11526492
GO:0009791	Process	Post-embryonic development	IEA
GO:0043565	Function	Sequence-specific DNA binding	IBA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	ISS	17726538
GO:0048008	Process	Platelet-derived growth factor receptor signaling pathway	IEA
GO:0048705	Process	Skeletal system morphogenesis	IEA
GO:0060021	Process	Roof of mouth development	IEA
GO:0060325	Process	Face morphogenesis	IEA

MIM	HGNC	e!Ensembl
606458	14300	ENSG00000144655

Q96S65

Protein name

Cysteine/serine-rich nuclear protein 1 (CSRNP-1) (Axin-1 up-regulated gene 1 protein) (Protein URAX1) (TGF-beta-induced apoptosis protein 3) (TAIP-3)

Protein function

Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May have a tumor-suppressor function. May play a role in apoptosis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16019	CSRNP_N	79 → 304	Cysteine/serine-rich nuclear protein N-terminus	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues. {ECO:0000269|PubMed:

Sequence

MTGLLKRKFDQLDEDNSSVSSSSSSSGCQSRSCSPSSSVSRAWDSEEEGPWDQMPLPDRD
FCGPRSFTPLSILKRARRERPGRVAFDGITVFYFPRCQGFTSVPSRGGCTLGMALRHSAC
RRFSLAEFAQEQARARHEKLRQRLKEEKLEMLQWKLSAAGVPQAEAGLPPVVDAIDDASV
EEDLAVAVAGGRLEEVSFLQPYPARRRRALLRASGVRRIDREEKRELQALRQSREDCGCH
CDRICDPETCSCSLAGIKCQMDHTAFPCGCCREGCENPMGRVEFNQARVQTHFIHTLTRL
QLEQEAESFRELEAPAQGSPPSPGEEALVPTFPLAKPPMNNELGDNSCSSDMTDSSTASS
SASGTSEAPDCPTHPGLPGPGFQPGVDDDSLARILSFSDSDFGGEEEEEEEGSVGNLDNL
SCFHPADIFGTSDPGGLASWTHSYSGCSFTSGVLDENANLDASCFLNGGLEGSREGSLPG
TSVPPSMDAGRSSSVDLSLSSCDSFELLQALPDYSLGPHYTSQKVSDSLDNIEAPHFPLP
GLSPPGDASSCFLESLMGFSEPAAEALDPFIDSQFEDTVPASLMEPVPV

Sequence length

589

Interactions

View interactions

CSRNP1 (cysteine and serine rich nuclear protein 1)