CLEC7A (C-type lectin domain containing 7A)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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64581 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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C-type lectin domain containing 7A |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CLEC7A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BGR, CANDF4, CD369, CLECSF12, DECTIN1, SCARE2 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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CANDF4 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunorec |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9BXN2 | ||||||||||
Protein name | C-type lectin domain family 7 member A (Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369) | ||||||||||
Protein function | Lectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi (PubMed:11567029, PubMed:12423684). Necessary for | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in peripheral blood leukocytes and dendritic cells. Detected in spleen, bone marrow, lung, muscle, stomach and placenta. {ECO:0000269|PubMed:11470510, ECO:0000269|PubMed:11491532, ECO:0000269|PubMed:11567029, ECO:00002 | ||||||||||
Sequence |
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Sequence length | 247 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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