Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6257
Gene name Gene Name - the full gene name approved by the HGNC.	Retinoid X receptor beta
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RXRB
Synonyms (NCBI Gene) Gene synonyms aliases	DAUDI6, H-2RIIBP, NR2B2, RCoR-1, RXR-beta, RXRbeta
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p21.32
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptor

Show/Hide all(276)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004176	hsa-miR-197-3p	Microarray	16822819
MIRT004235	hsa-miR-346	Microarray	16822819
MIRT016771	hsa-miR-335-5p	Microarray	18185580
MIRT028819	hsa-miR-26b-5p	Microarray	19088304
MIRT051998	hsa-let-7b-5p	CLASH	23622248
MIRT049481	hsa-miR-92a-3p	CLASH	23622248
MIRT042213	hsa-miR-484	CLASH	23622248
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT628659	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT628659	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT488003	hsa-miR-320e	PAR-CLIP	23592263
MIRT488002	hsa-miR-4524b-3p	PAR-CLIP	23592263
MIRT488001	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT488000	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT487999	hsa-miR-6805-5p	PAR-CLIP	23592263
MIRT487998	hsa-miR-6732-5p	PAR-CLIP	23592263
MIRT487997	hsa-miR-3960	PAR-CLIP	23592263
MIRT487996	hsa-miR-8072	PAR-CLIP	23592263
MIRT487995	hsa-miR-6077	PAR-CLIP	23592263
MIRT487994	hsa-miR-4467	PAR-CLIP	23592263
MIRT487993	hsa-miR-3180	PAR-CLIP	23592263
MIRT487992	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT487990	hsa-miR-3196	PAR-CLIP	23592263
MIRT487991	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT487989	hsa-miR-1237-5p	PAR-CLIP	23592263
MIRT487988	hsa-miR-4488	PAR-CLIP	23592263
MIRT487987	hsa-miR-4697-5p	PAR-CLIP	23592263
MIRT487986	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT487985	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT487984	hsa-miR-4278	PAR-CLIP	23592263
MIRT455426	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT455425	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT455424	hsa-miR-4418	PAR-CLIP	23592263
MIRT455423	hsa-miR-509-3-5p	PAR-CLIP	23592263
MIRT455422	hsa-miR-509-5p	PAR-CLIP	23592263
MIRT455421	hsa-miR-3158-5p	PAR-CLIP	23592263
MIRT455420	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT455419	hsa-miR-5002-3p	PAR-CLIP	23592263
MIRT455418	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT455417	hsa-miR-298	PAR-CLIP	23592263
MIRT455416	hsa-miR-3689d	PAR-CLIP	23592263
MIRT455414	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT455415	hsa-miR-3616-5p	PAR-CLIP	23592263
MIRT455413	hsa-miR-573	PAR-CLIP	23592263
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT628659	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT628659	hsa-miR-6769a-3p	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT610405	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT610404	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT610403	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT610402	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT004176	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT610401	hsa-miR-6083	HITS-CLIP	23824327
MIRT488003	hsa-miR-320e	PAR-CLIP	23592263
MIRT488002	hsa-miR-4524b-3p	PAR-CLIP	23592263
MIRT488001	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT488000	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT487999	hsa-miR-6805-5p	PAR-CLIP	23592263
MIRT487998	hsa-miR-6732-5p	PAR-CLIP	23592263
MIRT487997	hsa-miR-3960	PAR-CLIP	23592263
MIRT487996	hsa-miR-8072	PAR-CLIP	23592263
MIRT487995	hsa-miR-6077	PAR-CLIP	23592263
MIRT487994	hsa-miR-4467	PAR-CLIP	23592263
MIRT487993	hsa-miR-3180	PAR-CLIP	23592263
MIRT487992	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT487990	hsa-miR-3196	PAR-CLIP	23592263
MIRT487991	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT487989	hsa-miR-1237-5p	PAR-CLIP	23592263
MIRT487988	hsa-miR-4488	PAR-CLIP	23592263
MIRT487987	hsa-miR-4697-5p	PAR-CLIP	23592263
MIRT487986	hsa-miR-328-5p	PAR-CLIP	23592263
MIRT487985	hsa-miR-6885-5p	PAR-CLIP	23592263
MIRT487984	hsa-miR-4278	PAR-CLIP	23592263
MIRT455426	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT455425	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT455424	hsa-miR-4418	PAR-CLIP	23592263
MIRT455423	hsa-miR-509-3-5p	PAR-CLIP	23592263
MIRT455422	hsa-miR-509-5p	PAR-CLIP	23592263
MIRT455421	hsa-miR-3158-5p	PAR-CLIP	23592263
MIRT455420	hsa-miR-4795-5p	PAR-CLIP	23592263
MIRT455419	hsa-miR-5002-3p	PAR-CLIP	23592263
MIRT455418	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT455417	hsa-miR-298	PAR-CLIP	23592263
MIRT455416	hsa-miR-3689d	PAR-CLIP	23592263
MIRT455414	hsa-miR-6851-5p	PAR-CLIP	23592263
MIRT455415	hsa-miR-3616-5p	PAR-CLIP	23592263
MIRT455413	hsa-miR-573	PAR-CLIP	23592263
MIRT1323443	hsa-miR-1225-3p	CLIP-seq
MIRT1323444	hsa-miR-1253	CLIP-seq
MIRT1323445	hsa-miR-1291	CLIP-seq
MIRT1323446	hsa-miR-146b-3p	CLIP-seq
MIRT1323447	hsa-miR-1825	CLIP-seq
MIRT1323448	hsa-miR-188-5p	CLIP-seq
MIRT1323449	hsa-miR-1910	CLIP-seq
MIRT1323450	hsa-miR-1913	CLIP-seq
MIRT1323451	hsa-miR-199a-5p	CLIP-seq
MIRT1323452	hsa-miR-199b-5p	CLIP-seq
MIRT1323453	hsa-miR-2116	CLIP-seq
MIRT1323454	hsa-miR-3151	CLIP-seq
MIRT1323455	hsa-miR-3153	CLIP-seq
MIRT1323456	hsa-miR-3173-5p	CLIP-seq
MIRT1323457	hsa-miR-324-3p	CLIP-seq
MIRT1323458	hsa-miR-339-5p	CLIP-seq
MIRT1323459	hsa-miR-3682-5p	CLIP-seq
MIRT1323460	hsa-miR-3909	CLIP-seq
MIRT1323461	hsa-miR-3919	CLIP-seq
MIRT1323462	hsa-miR-3922-5p	CLIP-seq
MIRT1323463	hsa-miR-3924	CLIP-seq
MIRT1323464	hsa-miR-3925-3p	CLIP-seq
MIRT1323465	hsa-miR-4268	CLIP-seq
MIRT1323466	hsa-miR-4302	CLIP-seq
MIRT1323467	hsa-miR-432	CLIP-seq
MIRT1323468	hsa-miR-4323	CLIP-seq
MIRT1323469	hsa-miR-4443	CLIP-seq
MIRT1323470	hsa-miR-4447	CLIP-seq
MIRT1323471	hsa-miR-4448	CLIP-seq
MIRT1323472	hsa-miR-4472	CLIP-seq
MIRT1323473	hsa-miR-450b-3p	CLIP-seq
MIRT1323474	hsa-miR-4671-5p	CLIP-seq
MIRT1323475	hsa-miR-4677-5p	CLIP-seq
MIRT1323476	hsa-miR-4691-5p	CLIP-seq
MIRT1323477	hsa-miR-4712-3p	CLIP-seq
MIRT1323478	hsa-miR-4717-5p	CLIP-seq
MIRT1323479	hsa-miR-4727-5p	CLIP-seq
MIRT1323480	hsa-miR-4753-5p	CLIP-seq
MIRT1323481	hsa-miR-4756-3p	CLIP-seq
MIRT1323482	hsa-miR-4764-5p	CLIP-seq
MIRT1323483	hsa-miR-4775	CLIP-seq
MIRT1323484	hsa-miR-4780	CLIP-seq
MIRT1323485	hsa-miR-486-5p	CLIP-seq
MIRT1323486	hsa-miR-488	CLIP-seq
MIRT1323487	hsa-miR-491-5p	CLIP-seq
MIRT1323488	hsa-miR-513a-5p	CLIP-seq
MIRT1323489	hsa-miR-623	CLIP-seq
MIRT1323490	hsa-miR-629	CLIP-seq
MIRT1323491	hsa-miR-659	CLIP-seq
MIRT1323492	hsa-miR-769-3p	CLIP-seq
MIRT1323493	hsa-miR-874	CLIP-seq
MIRT2096030	hsa-miR-101	CLIP-seq
MIRT2096031	hsa-miR-144	CLIP-seq
MIRT2096032	hsa-miR-2276	CLIP-seq
MIRT1323459	hsa-miR-3682-5p	CLIP-seq
MIRT2096033	hsa-miR-4747-5p	CLIP-seq
MIRT2096034	hsa-miR-627	CLIP-seq
MIRT2096035	hsa-miR-924	CLIP-seq
MIRT2096030	hsa-miR-101	CLIP-seq
MIRT2320319	hsa-miR-1226	CLIP-seq
MIRT2320320	hsa-miR-1256	CLIP-seq
MIRT2096031	hsa-miR-144	CLIP-seq
MIRT1323450	hsa-miR-1913	CLIP-seq
MIRT2320321	hsa-miR-1915	CLIP-seq
MIRT2320322	hsa-miR-197	CLIP-seq
MIRT2320323	hsa-miR-3127-5p	CLIP-seq
MIRT2320324	hsa-miR-3135b	CLIP-seq
MIRT2320325	hsa-miR-3150b-3p	CLIP-seq
MIRT1323455	hsa-miR-3153	CLIP-seq
MIRT1323457	hsa-miR-324-3p	CLIP-seq
MIRT2320326	hsa-miR-3652	CLIP-seq
MIRT1323459	hsa-miR-3682-5p	CLIP-seq
MIRT2320327	hsa-miR-3689a-3p	CLIP-seq
MIRT2320328	hsa-miR-3689c	CLIP-seq
MIRT2320329	hsa-miR-3918	CLIP-seq
MIRT2320330	hsa-miR-412	CLIP-seq
MIRT2320331	hsa-miR-4313	CLIP-seq
MIRT2320332	hsa-miR-4430	CLIP-seq
MIRT2320333	hsa-miR-4446-3p	CLIP-seq
MIRT2320334	hsa-miR-4453	CLIP-seq
MIRT2320335	hsa-miR-4476	CLIP-seq
MIRT2320336	hsa-miR-4492	CLIP-seq
MIRT2320337	hsa-miR-4493	CLIP-seq
MIRT2320338	hsa-miR-4498	CLIP-seq
MIRT2320339	hsa-miR-4538	CLIP-seq
MIRT2320340	hsa-miR-455-5p	CLIP-seq
MIRT2320341	hsa-miR-4646-5p	CLIP-seq
MIRT2320342	hsa-miR-4668-5p	CLIP-seq
MIRT2320343	hsa-miR-4685-5p	CLIP-seq
MIRT2320344	hsa-miR-4714-3p	CLIP-seq
MIRT2320345	hsa-miR-4720-5p	CLIP-seq
MIRT2320346	hsa-miR-4728-5p	CLIP-seq
MIRT2320347	hsa-miR-4763-5p	CLIP-seq
MIRT2320348	hsa-miR-4784	CLIP-seq
MIRT2320349	hsa-miR-4799-3p	CLIP-seq
MIRT2320350	hsa-miR-490-3p	CLIP-seq
MIRT2320351	hsa-miR-548k	CLIP-seq
MIRT2320352	hsa-miR-762	CLIP-seq
MIRT2320353	hsa-miR-765	CLIP-seq
MIRT1323450	hsa-miR-1913	CLIP-seq
MIRT2320321	hsa-miR-1915	CLIP-seq
MIRT1323457	hsa-miR-324-3p	CLIP-seq
MIRT2320343	hsa-miR-4685-5p	CLIP-seq
MIRT2320322	hsa-miR-197	CLIP-seq
MIRT2320330	hsa-miR-412	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	12767074
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	12767074
GO:0003707	Function	Steroid hormone receptor activity	IEA
GO:0004879	Function	Nuclear receptor activity	IBA	21873635
GO:0004879	Function	Nuclear receptor activity	IDA	1662118, 7990953
GO:0005515	Function	Protein binding	IPI	16189514, 20195357, 21988832, 25303530, 25416956, 26871637, 28514442, 29892012, 31515488, 32296183
GO:0005634	Component	Nucleus	IDA	7990953
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0006367	Process	Transcription initiation from RNA polymerase II promoter	TAS
GO:0008270	Function	Zinc ion binding	IEA
GO:0030154	Process	Cell differentiation	IBA	21873635
GO:0032526	Process	Response to retinoic acid	IBA	21873635
GO:0043401	Process	Steroid hormone mediated signaling pathway	IEA
GO:0044323	Function	Retinoic acid-responsive element binding	IBA	21873635
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	1662118
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA	21873635
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	12767074
GO:0048384	Process	Retinoic acid receptor signaling pathway	IBA	21873635
GO:0048856	Process	Anatomical structure development	IBA	21873635
GO:0090575	Component	RNA polymerase II transcription regulator complex	IBA	21873635
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
180246	10478	ENSG00000204231

Protein

UniProt ID

P28702

Protein name

Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta)

Protein function

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR

PDB

1H9U , 1UHL , 5HJP , 5I4V , 5KYA , 5KYJ , 7A78

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00105	zf-C4	203 → 272	Zinc finger, C4 type (two domains)	Domain
PF00104	Hormone_recep	331 → 513	Ligand-binding domain of nuclear hormone receptor	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in aortic endothelial cells (at protein level) (PubMed:28167758). Expressed in monocytes (PubMed:26463675). Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:26463675, ECO:0000269|PubMed:28167758, ECO:0000269|Pu

Sequence

MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA

Sequence length

533

Interactions

View interactions

	KEGG		Reactome
	PPAR signaling pathway Th17 cell differentiation Thyroid hormone signaling pathway Adipocytokine signaling pathway Parathyroid hormone synthesis, secretion and action Pathways in cancer Transcriptional misregulation in cancer Chemical carcinogenesis - receptor activation Thyroid cancer Small cell lung cancer Non-small cell lung cancer Gastric cancer Lipid and atherosclerosis		PPARA activates gene expression Nuclear Receptor transcription pathway Signaling by Retinoic Acid NR1H2 & NR1H3 regulate gene expression linked to lipogenesis NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis

Show/Hide Causal Diseases (4)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)	22322885
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	22322885
Gastric cancer	Hereditary Diffuse Gastric Cancer	rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802 View all (244 more)	21364753
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465 View all (942 more)	22322885

Show/Hide Text Mining Associations (28)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Inhibit	12514092
Bile Duct Neoplasms	Associate	18375961
Breast Neoplasms	Associate	8384307
Carcinoma Basal Cell	Associate	12514092
Carcinoma Embryonal	Associate	1736309
Carcinoma Intraductal Noninfiltrating	Associate	11092983
Esophageal Squamous Cell Carcinoma	Associate	29098164
Eyelid Neoplasms	Associate	26503156
Gallstones	Associate	18375961
Granulomatosis with Polyangiitis	Associate	16526951, 19811264
Heart Diseases	Associate	29928977
Lung Neoplasms	Inhibit	19961602
Lymphoma Large B Cell Diffuse	Associate	21148756
Lymphoma Non Hodgkin	Associate	21148756
Melanoma	Associate	9228081
Mouth Neoplasms	Associate	24322297
Neoplasm Metastasis	Associate	24322297
Neoplasms	Associate	24322297
Neuroblastoma	Associate	11591367
Ossification of the posterior longitudinal ligament of the spine	Associate	10234570
Osteoarthritis	Associate	19217805
Ovarian Neoplasms	Associate	16012182
Pancreatic Neoplasms	Associate	29169171
Polycystic Kidney Autosomal Recessive	Associate	11092983
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	39465162
Prostatic Neoplasms	Associate	12514092
Sarcoidosis	Associate	16526951
Systemic Vasculitis	Associate	19811264

RXRB (retinoid X receptor beta)