Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	60493
Gene name Gene Name - the full gene name approved by the HGNC.	FAST kinase domains 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FASTKD5
Synonyms (NCBI Gene) Gene synonyms aliases	dJ1187M17.5
Chromosome Chromosome number	20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	20p13

Show/Hide all(106)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050449	hsa-miR-23a-3p	CLASH	23622248
MIRT989759	hsa-miR-1261	CLIP-seq
MIRT989760	hsa-miR-128	CLIP-seq
MIRT989761	hsa-miR-149	CLIP-seq
MIRT989762	hsa-miR-181a	CLIP-seq
MIRT989763	hsa-miR-181b	CLIP-seq
MIRT989764	hsa-miR-181c	CLIP-seq
MIRT989765	hsa-miR-181d	CLIP-seq
MIRT989766	hsa-miR-27a	CLIP-seq
MIRT989767	hsa-miR-27b	CLIP-seq
MIRT989768	hsa-miR-3064-5p	CLIP-seq
MIRT989769	hsa-miR-3119	CLIP-seq
MIRT989770	hsa-miR-323-3p	CLIP-seq
MIRT989771	hsa-miR-374a	CLIP-seq
MIRT989772	hsa-miR-374b	CLIP-seq
MIRT989773	hsa-miR-4262	CLIP-seq
MIRT989774	hsa-miR-4312	CLIP-seq
MIRT989775	hsa-miR-450b-5p	CLIP-seq
MIRT989776	hsa-miR-4661-5p	CLIP-seq
MIRT989777	hsa-miR-4666-3p	CLIP-seq
MIRT989778	hsa-miR-4704-5p	CLIP-seq
MIRT989779	hsa-miR-4794	CLIP-seq
MIRT989780	hsa-miR-4803	CLIP-seq
MIRT989781	hsa-miR-490-3p	CLIP-seq
MIRT989782	hsa-miR-507	CLIP-seq
MIRT989783	hsa-miR-513a-5p	CLIP-seq
MIRT989784	hsa-miR-557	CLIP-seq
MIRT989785	hsa-miR-649	CLIP-seq
MIRT989786	hsa-miR-802	CLIP-seq
MIRT989760	hsa-miR-128	CLIP-seq
MIRT989766	hsa-miR-27a	CLIP-seq
MIRT989767	hsa-miR-27b	CLIP-seq
MIRT989770	hsa-miR-323-3p	CLIP-seq
MIRT989776	hsa-miR-4661-5p	CLIP-seq
MIRT1993335	hsa-miR-4699-3p	CLIP-seq
MIRT989778	hsa-miR-4704-5p	CLIP-seq
MIRT1993336	hsa-miR-4795-3p	CLIP-seq
MIRT989780	hsa-miR-4803	CLIP-seq
MIRT989781	hsa-miR-490-3p	CLIP-seq
MIRT989783	hsa-miR-513a-5p	CLIP-seq
MIRT989785	hsa-miR-649	CLIP-seq
MIRT989786	hsa-miR-802	CLIP-seq
MIRT989760	hsa-miR-128	CLIP-seq
MIRT989766	hsa-miR-27a	CLIP-seq
MIRT989767	hsa-miR-27b	CLIP-seq
MIRT989770	hsa-miR-323-3p	CLIP-seq
MIRT989776	hsa-miR-4661-5p	CLIP-seq
MIRT989778	hsa-miR-4704-5p	CLIP-seq
MIRT989780	hsa-miR-4803	CLIP-seq
MIRT989781	hsa-miR-490-3p	CLIP-seq
MIRT989783	hsa-miR-513a-5p	CLIP-seq
MIRT989785	hsa-miR-649	CLIP-seq
MIRT989786	hsa-miR-802	CLIP-seq
MIRT2531133	hsa-miR-101	CLIP-seq
MIRT989759	hsa-miR-1261	CLIP-seq
MIRT2531134	hsa-miR-1264	CLIP-seq
MIRT2531135	hsa-miR-144	CLIP-seq
MIRT989761	hsa-miR-149	CLIP-seq
MIRT989762	hsa-miR-181a	CLIP-seq
MIRT989763	hsa-miR-181b	CLIP-seq
MIRT989764	hsa-miR-181c	CLIP-seq
MIRT989765	hsa-miR-181d	CLIP-seq
MIRT989768	hsa-miR-3064-5p	CLIP-seq
MIRT989769	hsa-miR-3119	CLIP-seq
MIRT989771	hsa-miR-374a	CLIP-seq
MIRT989772	hsa-miR-374b	CLIP-seq
MIRT989773	hsa-miR-4262	CLIP-seq
MIRT2531136	hsa-miR-4279	CLIP-seq
MIRT989774	hsa-miR-4312	CLIP-seq
MIRT989775	hsa-miR-450b-5p	CLIP-seq
MIRT989776	hsa-miR-4661-5p	CLIP-seq
MIRT989777	hsa-miR-4666-3p	CLIP-seq
MIRT989778	hsa-miR-4704-5p	CLIP-seq
MIRT2531137	hsa-miR-4789-5p	CLIP-seq
MIRT989779	hsa-miR-4794	CLIP-seq
MIRT989781	hsa-miR-490-3p	CLIP-seq
MIRT989782	hsa-miR-507	CLIP-seq
MIRT989784	hsa-miR-557	CLIP-seq
MIRT2531138	hsa-miR-603	CLIP-seq
MIRT989785	hsa-miR-649	CLIP-seq
MIRT2531133	hsa-miR-101	CLIP-seq
MIRT989759	hsa-miR-1261	CLIP-seq
MIRT2531134	hsa-miR-1264	CLIP-seq
MIRT2531135	hsa-miR-144	CLIP-seq
MIRT989761	hsa-miR-149	CLIP-seq
MIRT989762	hsa-miR-181a	CLIP-seq
MIRT989763	hsa-miR-181b	CLIP-seq
MIRT989764	hsa-miR-181c	CLIP-seq
MIRT989765	hsa-miR-181d	CLIP-seq
MIRT989768	hsa-miR-3064-5p	CLIP-seq
MIRT989769	hsa-miR-3119	CLIP-seq
MIRT989771	hsa-miR-374a	CLIP-seq
MIRT989772	hsa-miR-374b	CLIP-seq
MIRT989773	hsa-miR-4262	CLIP-seq
MIRT2531136	hsa-miR-4279	CLIP-seq
MIRT989774	hsa-miR-4312	CLIP-seq
MIRT989775	hsa-miR-450b-5p	CLIP-seq
MIRT989776	hsa-miR-4661-5p	CLIP-seq
MIRT989777	hsa-miR-4666-3p	CLIP-seq
MIRT989778	hsa-miR-4704-5p	CLIP-seq
MIRT989779	hsa-miR-4794	CLIP-seq
MIRT989781	hsa-miR-490-3p	CLIP-seq
MIRT989782	hsa-miR-507	CLIP-seq
MIRT989784	hsa-miR-557	CLIP-seq
MIRT2531138	hsa-miR-603	CLIP-seq
MIRT989785	hsa-miR-649	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000963	Process	Mitochondrial RNA processing	IMP	25683715
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	25416956, 30126976, 32296183, 32814053
GO:0005739	Component	Mitochondrion	IDA	20869947
GO:0006397	Process	MRNA processing	IEA
GO:0019843	Function	RRNA binding	IDA	25683715
GO:0035770	Component	Ribonucleoprotein granule	IDA	25683715
GO:0042645	Component	Mitochondrial nucleoid	IDA	25683715
GO:0044528	Process	Regulation of mitochondrial mRNA stability	IEA

MIM	HGNC	e!Ensembl
614272	25790	ENSG00000215251

Protein

UniProt ID

Q7L8L6

Protein name

FAST kinase domain-containing protein 5, mitochondrial

Protein function

Plays an important role in the processing of non-canonical mitochondrial mRNA precursors (PubMed:25683715).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06743	FAST_1	431 → 500	FAST kinase-like protein, subdomain 1	Family
PF08368	FAST_2	511 → 602	FAST kinase-like protein, subdomain 2	Family
PF08373	RAP	699 → 758	RAP domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid. {ECO:0000269|PubMed:20869947}.

Sequence

MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC
STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ
LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV
LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN
MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ
KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV
KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP
RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA
FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE
GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP
LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK
AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM
KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL

Sequence length

764

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	21822266

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Melanoma	Associate	34768773
Neoplasms	Associate	34768773
Stomach Neoplasms	Associate	34768773
Uterine Neoplasms	Associate	34768773

FASTKD5 (FAST kinase domains 5)