Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	60312
Gene name Gene Name - the full gene name approved by the HGNC.	Actin filament associated protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AFAP1
Synonyms (NCBI Gene) Gene synonyms aliases	AFAP, AFAP-110, AFAP110
Chromosome Chromosome number	4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	4p16.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling prot

Show/Hide all(549)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023977	hsa-miR-1-3p	Proteomics	18668040
MIRT029985	hsa-miR-26b-5p	Microarray	19088304
MIRT722720	hsa-miR-578	HITS-CLIP	19536157
MIRT660869	hsa-miR-548a-3p	HITS-CLIP	23824327
MIRT660868	hsa-miR-548ar-3p	HITS-CLIP	23824327
MIRT660867	hsa-miR-548az-3p	HITS-CLIP	23824327
MIRT660866	hsa-miR-548e-3p	HITS-CLIP	23824327
MIRT660865	hsa-miR-548f-3p	HITS-CLIP	23824327
MIRT660863	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT660864	hsa-miR-4802-3p	HITS-CLIP	23824327
MIRT660862	hsa-miR-942-3p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT660861	hsa-let-7a-3p	HITS-CLIP	23824327
MIRT660860	hsa-let-7b-3p	HITS-CLIP	23824327
MIRT660859	hsa-let-7f-1-3p	HITS-CLIP	23824327
MIRT660858	hsa-miR-98-3p	HITS-CLIP	23824327
MIRT660857	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT660856	hsa-let-7f-2-3p	HITS-CLIP	23824327
MIRT660855	hsa-miR-1185-1-3p	HITS-CLIP	23824327
MIRT660854	hsa-miR-1185-2-3p	HITS-CLIP	23824327
MIRT636731	hsa-miR-646	HITS-CLIP	23824327
MIRT636730	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT636731	hsa-miR-646	HITS-CLIP	23824327
MIRT636730	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT736699	hsa-miR-497-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32509208
MIRT722720	hsa-miR-578	HITS-CLIP	19536157
MIRT660869	hsa-miR-548a-3p	HITS-CLIP	23824327
MIRT660868	hsa-miR-548ar-3p	HITS-CLIP	23824327
MIRT660867	hsa-miR-548az-3p	HITS-CLIP	23824327
MIRT660866	hsa-miR-548e-3p	HITS-CLIP	23824327
MIRT660865	hsa-miR-548f-3p	HITS-CLIP	23824327
MIRT660863	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT660864	hsa-miR-4802-3p	HITS-CLIP	23824327
MIRT660862	hsa-miR-942-3p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT660861	hsa-let-7a-3p	HITS-CLIP	23824327
MIRT660860	hsa-let-7b-3p	HITS-CLIP	23824327
MIRT660859	hsa-let-7f-1-3p	HITS-CLIP	23824327
MIRT660858	hsa-miR-98-3p	HITS-CLIP	23824327
MIRT660857	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT660856	hsa-let-7f-2-3p	HITS-CLIP	23824327
MIRT660855	hsa-miR-1185-1-3p	HITS-CLIP	23824327
MIRT660854	hsa-miR-1185-2-3p	HITS-CLIP	23824327
MIRT636731	hsa-miR-646	HITS-CLIP	23824327
MIRT636730	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT636731	hsa-miR-646	HITS-CLIP	23824327
MIRT636730	hsa-miR-2115-5p	HITS-CLIP	23824327
MIRT636729	hsa-miR-3613-5p	HITS-CLIP	23824327
MIRT770757	hsa-miR-1257	CLIP-seq
MIRT770758	hsa-miR-1324	CLIP-seq
MIRT770759	hsa-miR-3166	CLIP-seq
MIRT770760	hsa-miR-3678-3p	CLIP-seq
MIRT770761	hsa-miR-3691-5p	CLIP-seq
MIRT770762	hsa-miR-4300	CLIP-seq
MIRT770763	hsa-miR-4701-5p	CLIP-seq
MIRT770764	hsa-miR-4752	CLIP-seq
MIRT770765	hsa-miR-4764-5p	CLIP-seq
MIRT770766	hsa-miR-4771	CLIP-seq
MIRT770767	hsa-miR-490-3p	CLIP-seq
MIRT770768	hsa-miR-520d-5p	CLIP-seq
MIRT770769	hsa-miR-524-5p	CLIP-seq
MIRT770770	hsa-miR-588	CLIP-seq
MIRT770771	hsa-miR-634	CLIP-seq
MIRT770772	hsa-miR-644	CLIP-seq
MIRT770773	hsa-miR-663b	CLIP-seq
MIRT770774	hsa-miR-920	CLIP-seq
MIRT770775	hsa-miR-939	CLIP-seq
MIRT770776	hsa-miR-101	CLIP-seq
MIRT770777	hsa-miR-1271	CLIP-seq
MIRT770778	hsa-miR-128	CLIP-seq
MIRT770779	hsa-miR-1285	CLIP-seq
MIRT770780	hsa-miR-1289	CLIP-seq
MIRT770781	hsa-miR-1301	CLIP-seq
MIRT770782	hsa-miR-134	CLIP-seq
MIRT770783	hsa-miR-1343	CLIP-seq
MIRT770784	hsa-miR-144	CLIP-seq
MIRT770785	hsa-miR-182	CLIP-seq
MIRT770786	hsa-miR-186	CLIP-seq
MIRT770787	hsa-miR-2117	CLIP-seq
MIRT770788	hsa-miR-25	CLIP-seq
MIRT770789	hsa-miR-27a	CLIP-seq
MIRT770790	hsa-miR-27b	CLIP-seq
MIRT770791	hsa-miR-300	CLIP-seq
MIRT770792	hsa-miR-3064-3p	CLIP-seq
MIRT770793	hsa-miR-3074-5p	CLIP-seq
MIRT770794	hsa-miR-3118	CLIP-seq
MIRT770795	hsa-miR-3125	CLIP-seq
MIRT770796	hsa-miR-3153	CLIP-seq
MIRT770797	hsa-miR-3187-5p	CLIP-seq
MIRT770798	hsa-miR-3198	CLIP-seq
MIRT770799	hsa-miR-32	CLIP-seq
MIRT770800	hsa-miR-320a	CLIP-seq
MIRT770801	hsa-miR-320b	CLIP-seq
MIRT770802	hsa-miR-320c	CLIP-seq
MIRT770803	hsa-miR-320d	CLIP-seq
MIRT770804	hsa-miR-320e	CLIP-seq
MIRT770805	hsa-miR-326	CLIP-seq
MIRT770806	hsa-miR-330-3p	CLIP-seq
MIRT770807	hsa-miR-330-5p	CLIP-seq
MIRT770808	hsa-miR-342-3p	CLIP-seq
MIRT770809	hsa-miR-342-5p	CLIP-seq
MIRT770810	hsa-miR-3616-5p	CLIP-seq
MIRT770811	hsa-miR-363	CLIP-seq
MIRT770812	hsa-miR-3647-5p	CLIP-seq
MIRT770813	hsa-miR-3653	CLIP-seq
MIRT770814	hsa-miR-3664-5p	CLIP-seq
MIRT770815	hsa-miR-367	CLIP-seq
MIRT770816	hsa-miR-3670	CLIP-seq
MIRT770817	hsa-miR-377	CLIP-seq
MIRT770818	hsa-miR-378g	CLIP-seq
MIRT770819	hsa-miR-381	CLIP-seq
MIRT770820	hsa-miR-3916	CLIP-seq
MIRT770821	hsa-miR-3936	CLIP-seq
MIRT770822	hsa-miR-3944-5p	CLIP-seq
MIRT770823	hsa-miR-4264	CLIP-seq
MIRT770824	hsa-miR-4277	CLIP-seq
MIRT770825	hsa-miR-4294	CLIP-seq
MIRT770826	hsa-miR-4309	CLIP-seq
MIRT770827	hsa-miR-4326	CLIP-seq
MIRT770828	hsa-miR-4429	CLIP-seq
MIRT770829	hsa-miR-4440	CLIP-seq
MIRT770830	hsa-miR-4470	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT770832	hsa-miR-4486	CLIP-seq
MIRT770833	hsa-miR-4496	CLIP-seq
MIRT770834	hsa-miR-4504	CLIP-seq
MIRT770835	hsa-miR-451b	CLIP-seq
MIRT770836	hsa-miR-4635	CLIP-seq
MIRT770837	hsa-miR-4646-5p	CLIP-seq
MIRT770838	hsa-miR-4649-3p	CLIP-seq
MIRT770839	hsa-miR-4660	CLIP-seq
MIRT770840	hsa-miR-4664-5p	CLIP-seq
MIRT770841	hsa-miR-4668-5p	CLIP-seq
MIRT770842	hsa-miR-4680-5p	CLIP-seq
MIRT770843	hsa-miR-4690-5p	CLIP-seq
MIRT770844	hsa-miR-4717-5p	CLIP-seq
MIRT770845	hsa-miR-4722-3p	CLIP-seq
MIRT770846	hsa-miR-4753-3p	CLIP-seq
MIRT770847	hsa-miR-4795-5p	CLIP-seq
MIRT770848	hsa-miR-5047	CLIP-seq
MIRT770849	hsa-miR-513a-5p	CLIP-seq
MIRT770850	hsa-miR-516a-3p	CLIP-seq
MIRT770851	hsa-miR-516b	CLIP-seq
MIRT770852	hsa-miR-517a	CLIP-seq
MIRT770853	hsa-miR-517b	CLIP-seq
MIRT770854	hsa-miR-517c	CLIP-seq
MIRT770855	hsa-miR-542-3p	CLIP-seq
MIRT770856	hsa-miR-548a-5p	CLIP-seq
MIRT770857	hsa-miR-548ab	CLIP-seq
MIRT770858	hsa-miR-548ak	CLIP-seq
MIRT770859	hsa-miR-548b-5p	CLIP-seq
MIRT770860	hsa-miR-548c-5p	CLIP-seq
MIRT770861	hsa-miR-548d-5p	CLIP-seq
MIRT770862	hsa-miR-548h	CLIP-seq
MIRT770863	hsa-miR-548i	CLIP-seq
MIRT770864	hsa-miR-548j	CLIP-seq
MIRT770865	hsa-miR-548n	CLIP-seq
MIRT770866	hsa-miR-548w	CLIP-seq
MIRT770867	hsa-miR-548y	CLIP-seq
MIRT770868	hsa-miR-549	CLIP-seq
MIRT770869	hsa-miR-559	CLIP-seq
MIRT770870	hsa-miR-573	CLIP-seq
MIRT770871	hsa-miR-582-5p	CLIP-seq
MIRT770872	hsa-miR-583	CLIP-seq
MIRT770873	hsa-miR-595	CLIP-seq
MIRT770874	hsa-miR-612	CLIP-seq
MIRT770875	hsa-miR-636	CLIP-seq
MIRT770876	hsa-miR-642b	CLIP-seq
MIRT770877	hsa-miR-651	CLIP-seq
MIRT770878	hsa-miR-9	CLIP-seq
MIRT770879	hsa-miR-92a	CLIP-seq
MIRT770880	hsa-miR-92b	CLIP-seq
MIRT770881	hsa-miR-936	CLIP-seq
MIRT770882	hsa-miR-943	CLIP-seq
MIRT770883	hsa-miR-96	CLIP-seq
MIRT1545174	hsa-miR-34c-3p	CLIP-seq
MIRT1545175	hsa-miR-4422	CLIP-seq
MIRT1555900	hsa-miR-4670-3p	CLIP-seq
MIRT1927295	hsa-miR-1184	CLIP-seq
MIRT1927296	hsa-miR-1185	CLIP-seq
MIRT1927297	hsa-miR-1204	CLIP-seq
MIRT1927298	hsa-miR-1205	CLIP-seq
MIRT1927299	hsa-miR-1208	CLIP-seq
MIRT1927300	hsa-miR-1227	CLIP-seq
MIRT1927301	hsa-miR-1233	CLIP-seq
MIRT1927302	hsa-miR-1238	CLIP-seq
MIRT1927303	hsa-miR-1245b-3p	CLIP-seq
MIRT1927304	hsa-miR-125a-3p	CLIP-seq
MIRT770778	hsa-miR-128	CLIP-seq
MIRT1927305	hsa-miR-1288	CLIP-seq
MIRT1927306	hsa-miR-1290	CLIP-seq
MIRT1927307	hsa-miR-1297	CLIP-seq
MIRT1927308	hsa-miR-1299	CLIP-seq
MIRT770782	hsa-miR-134	CLIP-seq
MIRT770783	hsa-miR-1343	CLIP-seq
MIRT1927309	hsa-miR-135a	CLIP-seq
MIRT1927310	hsa-miR-135b	CLIP-seq
MIRT770784	hsa-miR-144	CLIP-seq
MIRT1927311	hsa-miR-183	CLIP-seq
MIRT1927312	hsa-miR-185	CLIP-seq
MIRT1927313	hsa-miR-2052	CLIP-seq
MIRT1927314	hsa-miR-2110	CLIP-seq
MIRT1927315	hsa-miR-2115	CLIP-seq
MIRT1927316	hsa-miR-24	CLIP-seq
MIRT1927317	hsa-miR-26a	CLIP-seq
MIRT1927318	hsa-miR-26b	CLIP-seq
MIRT770789	hsa-miR-27a	CLIP-seq
MIRT770790	hsa-miR-27b	CLIP-seq
MIRT1927319	hsa-miR-31	CLIP-seq
MIRT1927320	hsa-miR-3117-5p	CLIP-seq
MIRT770794	hsa-miR-3118	CLIP-seq
MIRT1927321	hsa-miR-3119	CLIP-seq
MIRT1927322	hsa-miR-3122	CLIP-seq
MIRT1927323	hsa-miR-3127-5p	CLIP-seq
MIRT1927324	hsa-miR-3128	CLIP-seq
MIRT1927325	hsa-miR-3140-3p	CLIP-seq
MIRT1927326	hsa-miR-3143	CLIP-seq
MIRT1927327	hsa-miR-3144-5p	CLIP-seq
MIRT1927328	hsa-miR-3150a-3p	CLIP-seq
MIRT1927329	hsa-miR-3158-5p	CLIP-seq
MIRT1927330	hsa-miR-3159	CLIP-seq
MIRT1927331	hsa-miR-3163	CLIP-seq
MIRT1927332	hsa-miR-3164	CLIP-seq
MIRT1927333	hsa-miR-3169	CLIP-seq
MIRT1927334	hsa-miR-3179	CLIP-seq
MIRT1927335	hsa-miR-3180	CLIP-seq
MIRT1927336	hsa-miR-3180-3p	CLIP-seq
MIRT1927337	hsa-miR-3189-5p	CLIP-seq
MIRT1927338	hsa-miR-3196	CLIP-seq
MIRT1927339	hsa-miR-3202	CLIP-seq
MIRT770804	hsa-miR-320e	CLIP-seq
MIRT1927340	hsa-miR-3605-5p	CLIP-seq
MIRT770813	hsa-miR-3653	CLIP-seq
MIRT1927341	hsa-miR-3662	CLIP-seq
MIRT770814	hsa-miR-3664-5p	CLIP-seq
MIRT1927342	hsa-miR-3679-5p	CLIP-seq
MIRT1927343	hsa-miR-3689a-3p	CLIP-seq
MIRT1927344	hsa-miR-3689c	CLIP-seq
MIRT770817	hsa-miR-377	CLIP-seq
MIRT1927345	hsa-miR-3913-3p	CLIP-seq
MIRT1927346	hsa-miR-3913-5p	CLIP-seq
MIRT1927347	hsa-miR-3934	CLIP-seq
MIRT1927348	hsa-miR-4253	CLIP-seq
MIRT1927349	hsa-miR-4267	CLIP-seq
MIRT1927350	hsa-miR-4271	CLIP-seq
MIRT1927351	hsa-miR-4284	CLIP-seq
MIRT1927352	hsa-miR-4306	CLIP-seq
MIRT1927353	hsa-miR-4307	CLIP-seq
MIRT1927354	hsa-miR-4313	CLIP-seq
MIRT1927355	hsa-miR-4318	CLIP-seq
MIRT1927356	hsa-miR-4323	CLIP-seq
MIRT770827	hsa-miR-4326	CLIP-seq
MIRT1927357	hsa-miR-4419a	CLIP-seq
MIRT1927358	hsa-miR-4426	CLIP-seq
MIRT1927359	hsa-miR-4436a	CLIP-seq
MIRT1927360	hsa-miR-4465	CLIP-seq
MIRT1927361	hsa-miR-4474-3p	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT1927362	hsa-miR-4493	CLIP-seq
MIRT770834	hsa-miR-4504	CLIP-seq
MIRT1927363	hsa-miR-450b-5p	CLIP-seq
MIRT1927364	hsa-miR-4510	CLIP-seq
MIRT1927365	hsa-miR-4515	CLIP-seq
MIRT1927366	hsa-miR-4520a-3p	CLIP-seq
MIRT1927367	hsa-miR-4641	CLIP-seq
MIRT1927368	hsa-miR-4644	CLIP-seq
MIRT1927369	hsa-miR-4647	CLIP-seq
MIRT1927370	hsa-miR-4662b	CLIP-seq
MIRT770842	hsa-miR-4680-5p	CLIP-seq
MIRT1927371	hsa-miR-4699-3p	CLIP-seq
MIRT770763	hsa-miR-4701-5p	CLIP-seq
MIRT1927372	hsa-miR-4720-5p	CLIP-seq
MIRT1927373	hsa-miR-4725-3p	CLIP-seq
MIRT1927374	hsa-miR-4728-5p	CLIP-seq
MIRT1927375	hsa-miR-4742-3p	CLIP-seq
MIRT1927376	hsa-miR-4747-5p	CLIP-seq
MIRT1927377	hsa-miR-4761-5p	CLIP-seq
MIRT1927378	hsa-miR-4763-5p	CLIP-seq
MIRT770765	hsa-miR-4764-5p	CLIP-seq
MIRT1927379	hsa-miR-4782-5p	CLIP-seq
MIRT1927380	hsa-miR-4799-3p	CLIP-seq
MIRT1927381	hsa-miR-486-3p	CLIP-seq
MIRT1927382	hsa-miR-489	CLIP-seq
MIRT1927383	hsa-miR-493	CLIP-seq
MIRT1927384	hsa-miR-499-3p	CLIP-seq
MIRT1927385	hsa-miR-499a-3p	CLIP-seq
MIRT1927386	hsa-miR-512-3p	CLIP-seq
MIRT770849	hsa-miR-513a-5p	CLIP-seq
MIRT1927387	hsa-miR-513c	CLIP-seq
MIRT1927388	hsa-miR-514b-5p	CLIP-seq
MIRT1927389	hsa-miR-543	CLIP-seq
MIRT1927390	hsa-miR-544	CLIP-seq
MIRT1927391	hsa-miR-579	CLIP-seq
MIRT770871	hsa-miR-582-5p	CLIP-seq
MIRT770770	hsa-miR-588	CLIP-seq
MIRT1927392	hsa-miR-607	CLIP-seq
MIRT1927393	hsa-miR-630	CLIP-seq
MIRT770875	hsa-miR-636	CLIP-seq
MIRT1927394	hsa-miR-658	CLIP-seq
MIRT1927395	hsa-miR-659	CLIP-seq
MIRT1927396	hsa-miR-764	CLIP-seq
MIRT1927397	hsa-miR-873	CLIP-seq
MIRT1927398	hsa-miR-875-3p	CLIP-seq
MIRT770878	hsa-miR-9	CLIP-seq
MIRT770783	hsa-miR-1343	CLIP-seq
MIRT1927326	hsa-miR-3143	CLIP-seq
MIRT1927337	hsa-miR-3189-5p	CLIP-seq
MIRT770809	hsa-miR-342-5p	CLIP-seq
MIRT770813	hsa-miR-3653	CLIP-seq
MIRT770821	hsa-miR-3936	CLIP-seq
MIRT770827	hsa-miR-4326	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT1927362	hsa-miR-4493	CLIP-seq
MIRT770834	hsa-miR-4504	CLIP-seq
MIRT1927366	hsa-miR-4520a-3p	CLIP-seq
MIRT770840	hsa-miR-4664-5p	CLIP-seq
MIRT1927387	hsa-miR-513c	CLIP-seq
MIRT1927388	hsa-miR-514b-5p	CLIP-seq
MIRT1927389	hsa-miR-543	CLIP-seq
MIRT770868	hsa-miR-549	CLIP-seq
MIRT770875	hsa-miR-636	CLIP-seq
MIRT1927308	hsa-miR-1299	CLIP-seq
MIRT1927301	hsa-miR-1233	CLIP-seq
MIRT1927337	hsa-miR-3189-5p	CLIP-seq
MIRT2383987	hsa-miR-3617	CLIP-seq
MIRT770813	hsa-miR-3653	CLIP-seq
MIRT2383988	hsa-miR-3658	CLIP-seq
MIRT2383989	hsa-miR-4468	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT1927362	hsa-miR-4493	CLIP-seq
MIRT1927366	hsa-miR-4520a-3p	CLIP-seq
MIRT1927387	hsa-miR-513c	CLIP-seq
MIRT1927388	hsa-miR-514b-5p	CLIP-seq
MIRT2383990	hsa-miR-641	CLIP-seq
MIRT2383991	hsa-miR-665	CLIP-seq
MIRT2383992	hsa-miR-885-3p	CLIP-seq
MIRT1927319	hsa-miR-31	CLIP-seq
MIRT1927324	hsa-miR-3128	CLIP-seq
MIRT2426089	hsa-miR-3613-3p	CLIP-seq
MIRT1545175	hsa-miR-4422	CLIP-seq
MIRT1927358	hsa-miR-4426	CLIP-seq
MIRT2426090	hsa-miR-4517	CLIP-seq
MIRT1927369	hsa-miR-4647	CLIP-seq
MIRT1927370	hsa-miR-4662b	CLIP-seq
MIRT2426091	hsa-miR-4711-3p	CLIP-seq
MIRT1927372	hsa-miR-4720-5p	CLIP-seq
MIRT1927380	hsa-miR-4799-3p	CLIP-seq
MIRT2470770	hsa-miR-1178	CLIP-seq
MIRT2470771	hsa-miR-1202	CLIP-seq
MIRT1927298	hsa-miR-1205	CLIP-seq
MIRT2470772	hsa-miR-1207-3p	CLIP-seq
MIRT2470773	hsa-miR-1224-3p	CLIP-seq
MIRT2470774	hsa-miR-1225-3p	CLIP-seq
MIRT1927301	hsa-miR-1233	CLIP-seq
MIRT2470775	hsa-miR-1254	CLIP-seq
MIRT2470776	hsa-miR-125a-5p	CLIP-seq
MIRT2470777	hsa-miR-125b	CLIP-seq
MIRT2470778	hsa-miR-1264	CLIP-seq
MIRT770777	hsa-miR-1271	CLIP-seq
MIRT770778	hsa-miR-128	CLIP-seq
MIRT2470779	hsa-miR-1305	CLIP-seq
MIRT770783	hsa-miR-1343	CLIP-seq
MIRT770784	hsa-miR-144	CLIP-seq
MIRT770785	hsa-miR-182	CLIP-seq
MIRT2470780	hsa-miR-1909	CLIP-seq
MIRT2470781	hsa-miR-1914	CLIP-seq
MIRT770787	hsa-miR-2117	CLIP-seq
MIRT2470782	hsa-miR-2277-3p	CLIP-seq
MIRT1927316	hsa-miR-24	CLIP-seq
MIRT770789	hsa-miR-27a	CLIP-seq
MIRT770790	hsa-miR-27b	CLIP-seq
MIRT2470783	hsa-miR-2909	CLIP-seq
MIRT770792	hsa-miR-3064-3p	CLIP-seq
MIRT2470784	hsa-miR-3065-5p	CLIP-seq
MIRT2470785	hsa-miR-3116	CLIP-seq
MIRT1927320	hsa-miR-3117-5p	CLIP-seq
MIRT2470786	hsa-miR-3123	CLIP-seq
MIRT770795	hsa-miR-3125	CLIP-seq
MIRT2470787	hsa-miR-3136-3p	CLIP-seq
MIRT1927326	hsa-miR-3143	CLIP-seq
MIRT2470788	hsa-miR-3155	CLIP-seq
MIRT2470789	hsa-miR-3155b	CLIP-seq
MIRT1927332	hsa-miR-3164	CLIP-seq
MIRT2470790	hsa-miR-3187-3p	CLIP-seq
MIRT1927337	hsa-miR-3189-5p	CLIP-seq
MIRT2470791	hsa-miR-3192	CLIP-seq
MIRT2470792	hsa-miR-3194-5p	CLIP-seq
MIRT1927339	hsa-miR-3202	CLIP-seq
MIRT770804	hsa-miR-320e	CLIP-seq
MIRT770806	hsa-miR-330-3p	CLIP-seq
MIRT770808	hsa-miR-342-3p	CLIP-seq
MIRT2470793	hsa-miR-3620	CLIP-seq
MIRT2470794	hsa-miR-3622a-3p	CLIP-seq
MIRT2470795	hsa-miR-3622b-3p	CLIP-seq
MIRT2470796	hsa-miR-3661	CLIP-seq
MIRT2470797	hsa-miR-3667-3p	CLIP-seq
MIRT2470798	hsa-miR-3677-5p	CLIP-seq
MIRT2470799	hsa-miR-371-5p	CLIP-seq
MIRT770817	hsa-miR-377	CLIP-seq
MIRT2470800	hsa-miR-380	CLIP-seq
MIRT770820	hsa-miR-3916	CLIP-seq
MIRT2470801	hsa-miR-3924	CLIP-seq
MIRT2470802	hsa-miR-3972	CLIP-seq
MIRT2470803	hsa-miR-412	CLIP-seq
MIRT2470804	hsa-miR-4258	CLIP-seq
MIRT1927349	hsa-miR-4267	CLIP-seq
MIRT2470805	hsa-miR-4268	CLIP-seq
MIRT770824	hsa-miR-4277	CLIP-seq
MIRT1927351	hsa-miR-4284	CLIP-seq
MIRT2470806	hsa-miR-4299	CLIP-seq
MIRT2470807	hsa-miR-4311	CLIP-seq
MIRT1927354	hsa-miR-4313	CLIP-seq
MIRT2470808	hsa-miR-4317	CLIP-seq
MIRT1927355	hsa-miR-4318	CLIP-seq
MIRT2470809	hsa-miR-4319	CLIP-seq
MIRT1927356	hsa-miR-4323	CLIP-seq
MIRT2470810	hsa-miR-4435	CLIP-seq
MIRT2470811	hsa-miR-4448	CLIP-seq
MIRT2470812	hsa-miR-4456	CLIP-seq
MIRT770830	hsa-miR-4470	CLIP-seq
MIRT1927361	hsa-miR-4474-3p	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT2470813	hsa-miR-4490	CLIP-seq
MIRT1927362	hsa-miR-4493	CLIP-seq
MIRT2470814	hsa-miR-4495	CLIP-seq
MIRT770833	hsa-miR-4496	CLIP-seq
MIRT1927366	hsa-miR-4520a-3p	CLIP-seq
MIRT2470815	hsa-miR-4529-5p	CLIP-seq
MIRT2470816	hsa-miR-4533	CLIP-seq
MIRT2470817	hsa-miR-4632	CLIP-seq
MIRT2470818	hsa-miR-4640-5p	CLIP-seq
MIRT1927367	hsa-miR-4641	CLIP-seq
MIRT2470819	hsa-miR-4651	CLIP-seq
MIRT2470820	hsa-miR-4690-3p	CLIP-seq
MIRT770843	hsa-miR-4690-5p	CLIP-seq
MIRT1927371	hsa-miR-4699-3p	CLIP-seq
MIRT2470821	hsa-miR-4707-3p	CLIP-seq
MIRT2470822	hsa-miR-4715-3p	CLIP-seq
MIRT770845	hsa-miR-4722-3p	CLIP-seq
MIRT2470823	hsa-miR-4726-5p	CLIP-seq
MIRT2470824	hsa-miR-4731-5p	CLIP-seq
MIRT1927376	hsa-miR-4747-5p	CLIP-seq
MIRT770846	hsa-miR-4753-3p	CLIP-seq
MIRT1927377	hsa-miR-4761-5p	CLIP-seq
MIRT2470825	hsa-miR-4796-5p	CLIP-seq
MIRT2470826	hsa-miR-4802-5p	CLIP-seq
MIRT2470827	hsa-miR-484	CLIP-seq
MIRT770767	hsa-miR-490-3p	CLIP-seq
MIRT1927383	hsa-miR-493	CLIP-seq
MIRT2470828	hsa-miR-494	CLIP-seq
MIRT2470829	hsa-miR-499a-5p	CLIP-seq
MIRT770849	hsa-miR-513a-5p	CLIP-seq
MIRT1927387	hsa-miR-513c	CLIP-seq
MIRT1927388	hsa-miR-514b-5p	CLIP-seq
MIRT770768	hsa-miR-520d-5p	CLIP-seq
MIRT770769	hsa-miR-524-5p	CLIP-seq
MIRT1927389	hsa-miR-543	CLIP-seq
MIRT770856	hsa-miR-548a-5p	CLIP-seq
MIRT770857	hsa-miR-548ab	CLIP-seq
MIRT770858	hsa-miR-548ak	CLIP-seq
MIRT2470830	hsa-miR-548al	CLIP-seq
MIRT770859	hsa-miR-548b-5p	CLIP-seq
MIRT2470831	hsa-miR-548c-3p	CLIP-seq
MIRT770860	hsa-miR-548c-5p	CLIP-seq
MIRT770861	hsa-miR-548d-5p	CLIP-seq
MIRT770862	hsa-miR-548h	CLIP-seq
MIRT770863	hsa-miR-548i	CLIP-seq
MIRT770864	hsa-miR-548j	CLIP-seq
MIRT770865	hsa-miR-548n	CLIP-seq
MIRT2470832	hsa-miR-548q	CLIP-seq
MIRT770866	hsa-miR-548w	CLIP-seq
MIRT770867	hsa-miR-548y	CLIP-seq
MIRT2470833	hsa-miR-555	CLIP-seq
MIRT770869	hsa-miR-559	CLIP-seq
MIRT1927391	hsa-miR-579	CLIP-seq
MIRT2470834	hsa-miR-586	CLIP-seq
MIRT1927392	hsa-miR-607	CLIP-seq
MIRT2470835	hsa-miR-608	CLIP-seq
MIRT2470836	hsa-miR-617	CLIP-seq
MIRT2470837	hsa-miR-629	CLIP-seq
MIRT2470838	hsa-miR-631	CLIP-seq
MIRT2470839	hsa-miR-637	CLIP-seq
MIRT2470840	hsa-miR-639	CLIP-seq
MIRT770877	hsa-miR-651	CLIP-seq
MIRT1927395	hsa-miR-659	CLIP-seq
MIRT2470841	hsa-miR-661	CLIP-seq
MIRT770773	hsa-miR-663b	CLIP-seq
MIRT2470842	hsa-miR-720	CLIP-seq
MIRT2470843	hsa-miR-765	CLIP-seq
MIRT2470844	hsa-miR-767-3p	CLIP-seq
MIRT1927397	hsa-miR-873	CLIP-seq
MIRT770878	hsa-miR-9	CLIP-seq
MIRT770883	hsa-miR-96	CLIP-seq
MIRT2470770	hsa-miR-1178	CLIP-seq
MIRT2470771	hsa-miR-1202	CLIP-seq
MIRT1927298	hsa-miR-1205	CLIP-seq
MIRT2470772	hsa-miR-1207-3p	CLIP-seq
MIRT2470780	hsa-miR-1909	CLIP-seq
MIRT770792	hsa-miR-3064-3p	CLIP-seq
MIRT1927320	hsa-miR-3117-5p	CLIP-seq
MIRT770795	hsa-miR-3125	CLIP-seq
MIRT1927326	hsa-miR-3143	CLIP-seq
MIRT2470792	hsa-miR-3194-5p	CLIP-seq
MIRT770804	hsa-miR-320e	CLIP-seq
MIRT770808	hsa-miR-342-3p	CLIP-seq
MIRT2470794	hsa-miR-3622a-3p	CLIP-seq
MIRT2470795	hsa-miR-3622b-3p	CLIP-seq
MIRT2470800	hsa-miR-380	CLIP-seq
MIRT770820	hsa-miR-3916	CLIP-seq
MIRT2470801	hsa-miR-3924	CLIP-seq
MIRT2470802	hsa-miR-3972	CLIP-seq
MIRT2470803	hsa-miR-412	CLIP-seq
MIRT2470804	hsa-miR-4258	CLIP-seq
MIRT1927349	hsa-miR-4267	CLIP-seq
MIRT2470808	hsa-miR-4317	CLIP-seq
MIRT1927356	hsa-miR-4323	CLIP-seq
MIRT770831	hsa-miR-4476	CLIP-seq
MIRT2470813	hsa-miR-4490	CLIP-seq
MIRT2470814	hsa-miR-4495	CLIP-seq
MIRT770833	hsa-miR-4496	CLIP-seq
MIRT2470817	hsa-miR-4632	CLIP-seq
MIRT2470821	hsa-miR-4707-3p	CLIP-seq
MIRT2470822	hsa-miR-4715-3p	CLIP-seq
MIRT770845	hsa-miR-4722-3p	CLIP-seq
MIRT1927376	hsa-miR-4747-5p	CLIP-seq
MIRT2470826	hsa-miR-4802-5p	CLIP-seq
MIRT1927383	hsa-miR-493	CLIP-seq
MIRT2470828	hsa-miR-494	CLIP-seq
MIRT1927389	hsa-miR-543	CLIP-seq
MIRT770856	hsa-miR-548a-5p	CLIP-seq
MIRT770857	hsa-miR-548ab	CLIP-seq
MIRT770858	hsa-miR-548ak	CLIP-seq
MIRT770859	hsa-miR-548b-5p	CLIP-seq
MIRT2470831	hsa-miR-548c-3p	CLIP-seq
MIRT770860	hsa-miR-548c-5p	CLIP-seq
MIRT770861	hsa-miR-548d-5p	CLIP-seq
MIRT770862	hsa-miR-548h	CLIP-seq
MIRT770863	hsa-miR-548i	CLIP-seq
MIRT770864	hsa-miR-548j	CLIP-seq
MIRT770865	hsa-miR-548n	CLIP-seq
MIRT770866	hsa-miR-548w	CLIP-seq
MIRT770867	hsa-miR-548y	CLIP-seq
MIRT770869	hsa-miR-559	CLIP-seq
MIRT770877	hsa-miR-651	CLIP-seq
MIRT2470843	hsa-miR-765	CLIP-seq
MIRT2470844	hsa-miR-767-3p	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IDA
GO:0009966	Process	Regulation of signal transduction	IEA
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0017124	Function	SH3 domain binding	IBA	21873635
GO:0042169	Function	SH2 domain binding	IBA	21873635
GO:0051493	Process	Regulation of cytoskeleton organization	IEA

MIM	HGNC	e!Ensembl
608252	24017	ENSG00000196526

Protein

UniProt ID

Q8N556

Protein name

Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)

Protein function

Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SR

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00169	PH	149 → 249	PH domain	Domain
PF00169	PH	333 → 438	PH domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Low expression in normal breast epithelial cell line MCF-10A and in tumorigenic breast cancer cell lines MCF-7, T-47D and ZR-75-1. Highly expressed in the invasive breast cancer cell lines MDA-MB-231 and MDA-MB-435. Overexpressed in pr

Sequence

MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLP
APPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSS
SYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTK
LLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQW
LKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKE
QVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNS
RWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAV
LEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISA
NPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNGVTGKGKTLSSQPKKADPA
AVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIE
VNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAIEPK
SGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRK
AKEWELKNGT

Sequence length

730

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Glaucoma	Glaucoma, Glaucoma, Open-Angle	rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328 View all (29 more)	30054594, 30104761, 25173105, 29891935

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Biliary Atresia	Biliary Atresia		GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients	GWAS, CBGDA

Show/Hide Text Mining Associations (45)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	23333711
Adenocarcinoma	Stimulate	27577754
Adenocarcinoma of Lung	Associate	35603556
Barrett Esophagus	Associate	23333711
Breast Neoplasms	Associate	29439313, 29458327, 32401758
Carcinogenesis	Associate	27628540, 37686205
Carcinoma Hepatocellular	Stimulate	27577754
Carcinoma Non Small Cell Lung	Associate	30278439
Carcinoma Non Small Cell Lung	Stimulate	30293090
Carcinoma Pancreatic Ductal	Associate	27628540
Colorectal Neoplasms	Stimulate	27577754
Colorectal Neoplasms	Associate	35616307
Esophageal Squamous Cell Carcinoma	Associate	26756568
Esophageal Squamous Cell Carcinoma	Stimulate	27577754
Gastritis	Associate	37249580
Glaucoma Open Angle	Associate	25173105, 29452408, 30352225, 35741817
Glioma	Associate	30178845, 36194351
Hirschsprung Disease	Associate	32959905
Insulin Resistance	Associate	34747338
Laryngeal Neoplasms	Stimulate	29971915
Laryngeal Neoplasms	Associate	35968243
Lung Neoplasms	Stimulate	26245991
Lung Neoplasms	Associate	30293090, 35603556
Lymphatic Metastasis	Stimulate	26756568, 28975981, 32016968
Nasopharyngeal Carcinoma	Stimulate	27577754
Nasopharyngeal Carcinoma	Associate	28380458, 28467811
Neoplasm Metastasis	Associate	26245991, 35616307
Neoplasm Metastasis	Stimulate	26756568, 28380458, 31081081, 32051698
Neoplasm Metastasis	Inhibit	29331858
Neoplasms	Associate	23333711, 26245991, 29331858, 29439313, 29654169, 29971915, 30178845, 30293090, 35968243, 37686205
Neoplasms	Stimulate	26756568, 27577754, 34334630, 35603556
Optic Nerve Diseases	Stimulate	29654169
Osteosarcoma	Associate	31002124
Ovarian Neoplasms	Associate	28051261
Ovarian Neoplasms	Stimulate	33926489
Pancreatic Neoplasms	Associate	25910082
Prostatic Neoplasms	Associate	31081081
Retinoblastoma	Associate	29654169, 35193469
Stomach Neoplasms	Stimulate	28975981, 32051698
Stomach Neoplasms	Associate	30320481, 32016968
Thymoma	Associate	34219124
Thyroid Neoplasms	Stimulate	29331858
Triple Negative Breast Neoplasms	Associate	32401758, 37686205
Urinary Bladder Neoplasms	Associate	32964963
Uterine Cervical Neoplasms	Associate	34334630

AFAP1 (actin filament associated protein 1)