Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
59084
Gene name Gene Name - the full gene name approved by the HGNC.
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ENPP5
Synonyms (NCBI Gene) Gene synonyms aliases
NPP-5, NPP5
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p21.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a type-I transmembrane glycoprotein. Studies in rat suggest the encoded protein may play a role in neuronal cell communications. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2014]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020237 hsa-miR-130b-3p Sequencing 20371350
MIRT031180 hsa-miR-19b-3p Sequencing 20371350
MIRT050870 hsa-miR-17-5p CLASH 23622248
MIRT712521 hsa-miR-3158-3p HITS-CLIP 19536157
MIRT712520 hsa-miR-3918 HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000210 Function NAD+ diphosphatase activity IDA 28898552
GO:0005576 Component Extracellular region IEA
GO:0005886 Component Plasma membrane ISS
GO:0007154 Process Cell communication ISS
GO:0008270 Function Zinc ion binding IDA 28898552
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
617001 13717 ENSG00000112796
Protein
UniProt ID Q9UJA9
Protein name Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-)
Protein function Can hydrolyze NAD but cannot hydrolyze nucleotide di- and triphosphates. Lacks lysopholipase D activity. May play a role in neuronal cell communication.
PDB 5VEM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01663 Phosphodiest 30 342 Type I phosphodiesterase / nucleotide pyrophosphatase Family
Sequence
Sequence length 477
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17013881
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Renal Cell Associate 37689589
Glaucoma Stimulate 39342991
Insulin Resistance Associate 30678306