PTPRK (protein tyrosine phosphatase receptor type K)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5796 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Protein tyrosine phosphatase receptor type K |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PTPRK |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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R-PTP-kappa |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q22.33 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tran |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||||||||||||
| UniProt ID | Q15262 | ||||||||||||||||||||||||||||||||||||||||
| Protein name | Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48) | ||||||||||||||||||||||||||||||||||||||||
| Protein function | Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may b | ||||||||||||||||||||||||||||||||||||||||
| PDB | 2C7S , 8A1F | ||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: High levels in lung, brain and colon; less in liver, pancreas, stomach, kidney, placenta and mammary carcinoma. | ||||||||||||||||||||||||||||||||||||||||
| Sequence | |||||||||||||||||||||||||||||||||||||||||
| Sequence length | 1439 | ||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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