Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5796
Gene name	Protein tyrosine phosphatase receptor type K
Gene symbol	PTPRK
Synonyms (NCBI Gene)	R-PTP-kappa
Chromosome	6
Chromosome location	6q22.33
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tran

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005161	hsa-miR-30a-5p	pSILAC	18668040
MIRT007126	hsa-miR-133b	Luciferase reporter assay	23451058
MIRT007126	hsa-miR-133b	Luciferase reporter assay	23451058
MIRT021457	hsa-miR-9-5p	Microarray	17612493
MIRT005161	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT045592	hsa-miR-149-5p	CLASH	23622248
MIRT042465	hsa-miR-423-3p	CLASH	23622248
MIRT039631	hsa-miR-615-3p	CLASH	23622248
MIRT037091	hsa-miR-877-3p	CLASH	23622248
MIRT036651	hsa-miR-935	CLASH	23622248
MIRT036651	hsa-miR-935	CLASH	23622248
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	21572407
MIRT546895	hsa-miR-1283	PAR-CLIP	21572407
MIRT439860	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439860	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT546895	hsa-miR-1283	PAR-CLIP	27292025
MIRT546895	hsa-miR-1283	PAR-CLIP	27292025
MIRT546895	hsa-miR-1283	PAR-CLIP	27292025
MIRT546895	hsa-miR-1283	PAR-CLIP	27292025
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	27292025
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	27292025
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	27292025
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	27292025
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	27292025
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	27292025
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	27292025
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	27292025
MIRT546897	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT546896	hsa-miR-7849-3p	PAR-CLIP	21572407
MIRT546895	hsa-miR-1283	PAR-CLIP	21572407
MIRT2081289	hsa-miR-105	CLIP-seq
MIRT2081290	hsa-miR-4699-3p	CLIP-seq
MIRT2081291	hsa-miR-4731-3p	CLIP-seq
MIRT2081292	hsa-miR-4801	CLIP-seq
MIRT2081293	hsa-miR-579	CLIP-seq
MIRT2307183	hsa-miR-1245b-5p	CLIP-seq
MIRT2307184	hsa-miR-1276	CLIP-seq
MIRT2307185	hsa-miR-1343	CLIP-seq
MIRT2307186	hsa-miR-136	CLIP-seq
MIRT2307187	hsa-miR-142-5p	CLIP-seq
MIRT2307188	hsa-miR-149	CLIP-seq
MIRT2307189	hsa-miR-186	CLIP-seq
MIRT2307190	hsa-miR-1910	CLIP-seq
MIRT2307191	hsa-miR-194	CLIP-seq
MIRT2307192	hsa-miR-2115	CLIP-seq
MIRT2307193	hsa-miR-218	CLIP-seq
MIRT2307194	hsa-miR-24	CLIP-seq
MIRT2307195	hsa-miR-299-5p	CLIP-seq
MIRT2307196	hsa-miR-29a	CLIP-seq
MIRT2307197	hsa-miR-29b	CLIP-seq
MIRT2307198	hsa-miR-29c	CLIP-seq
MIRT2307199	hsa-miR-3123	CLIP-seq
MIRT2307200	hsa-miR-3130-3p	CLIP-seq
MIRT2307201	hsa-miR-3133	CLIP-seq
MIRT2307202	hsa-miR-3142	CLIP-seq
MIRT2307203	hsa-miR-3160-3p	CLIP-seq
MIRT2307204	hsa-miR-3160-5p	CLIP-seq
MIRT2307205	hsa-miR-340	CLIP-seq
MIRT2307206	hsa-miR-34b	CLIP-seq
MIRT2307207	hsa-miR-34c-3p	CLIP-seq
MIRT2307208	hsa-miR-3653	CLIP-seq
MIRT2307209	hsa-miR-3658	CLIP-seq
MIRT2307210	hsa-miR-382	CLIP-seq
MIRT2307211	hsa-miR-3922-5p	CLIP-seq
MIRT2307212	hsa-miR-3977	CLIP-seq
MIRT2307213	hsa-miR-4284	CLIP-seq
MIRT2307214	hsa-miR-4291	CLIP-seq
MIRT2307215	hsa-miR-4311	CLIP-seq
MIRT2307216	hsa-miR-4325	CLIP-seq
MIRT2307217	hsa-miR-4477a	CLIP-seq
MIRT2307218	hsa-miR-4487	CLIP-seq
MIRT2307219	hsa-miR-4495	CLIP-seq
MIRT2307220	hsa-miR-4520a-3p	CLIP-seq
MIRT2307221	hsa-miR-455-3p	CLIP-seq
MIRT2307222	hsa-miR-4659a-3p	CLIP-seq
MIRT2307223	hsa-miR-4659b-3p	CLIP-seq
MIRT2307224	hsa-miR-4662a-3p	CLIP-seq
MIRT2307225	hsa-miR-4668-3p	CLIP-seq
MIRT2307226	hsa-miR-4680-5p	CLIP-seq
MIRT2307227	hsa-miR-4698	CLIP-seq
MIRT2081290	hsa-miR-4699-3p	CLIP-seq
MIRT2307228	hsa-miR-4708-3p	CLIP-seq
MIRT2307229	hsa-miR-4724-5p	CLIP-seq
MIRT2081291	hsa-miR-4731-3p	CLIP-seq
MIRT2307230	hsa-miR-4760-3p	CLIP-seq
MIRT2307231	hsa-miR-4778-3p	CLIP-seq
MIRT2307232	hsa-miR-4793-3p	CLIP-seq
MIRT2081292	hsa-miR-4801	CLIP-seq
MIRT2307233	hsa-miR-490-5p	CLIP-seq
MIRT2307234	hsa-miR-515-5p	CLIP-seq
MIRT2307235	hsa-miR-516a-3p	CLIP-seq
MIRT2307236	hsa-miR-544	CLIP-seq
MIRT2307237	hsa-miR-545	CLIP-seq
MIRT2307238	hsa-miR-548ae	CLIP-seq
MIRT2307239	hsa-miR-548aj	CLIP-seq
MIRT2307240	hsa-miR-548am	CLIP-seq
MIRT2307241	hsa-miR-548l	CLIP-seq
MIRT2307242	hsa-miR-548p	CLIP-seq
MIRT2307243	hsa-miR-548x	CLIP-seq
MIRT2307244	hsa-miR-556-5p	CLIP-seq
MIRT2307245	hsa-miR-558	CLIP-seq
MIRT2081293	hsa-miR-579	CLIP-seq
MIRT2307246	hsa-miR-583	CLIP-seq
MIRT2307247	hsa-miR-627	CLIP-seq
MIRT2307248	hsa-miR-636	CLIP-seq
MIRT2307249	hsa-miR-767-5p	CLIP-seq
MIRT2307250	hsa-miR-9	CLIP-seq
MIRT2307251	hsa-miR-924	CLIP-seq
MIRT2307217	hsa-miR-4477a	CLIP-seq
MIRT2307224	hsa-miR-4662a-3p	CLIP-seq
MIRT2081291	hsa-miR-4731-3p	CLIP-seq
MIRT2081292	hsa-miR-4801	CLIP-seq
MIRT2432335	hsa-miR-1178	CLIP-seq
MIRT2432336	hsa-miR-4645-3p	CLIP-seq
MIRT2432337	hsa-miR-4725-5p	CLIP-seq
MIRT2081291	hsa-miR-4731-3p	CLIP-seq
MIRT2432338	hsa-miR-4766-5p	CLIP-seq
MIRT2081292	hsa-miR-4801	CLIP-seq
MIRT2432339	hsa-miR-504	CLIP-seq
MIRT2432340	hsa-miR-582-5p	CLIP-seq
MIRT2307188	hsa-miR-149	CLIP-seq
MIRT2307194	hsa-miR-24	CLIP-seq
MIRT2307213	hsa-miR-4284	CLIP-seq
MIRT2307220	hsa-miR-4520a-3p	CLIP-seq
MIRT2307188	hsa-miR-149	CLIP-seq
MIRT2307194	hsa-miR-24	CLIP-seq
MIRT2307213	hsa-miR-4284	CLIP-seq
MIRT2307220	hsa-miR-4520a-3p	CLIP-seq
MIRT2432335	hsa-miR-1178	CLIP-seq
MIRT2604670	hsa-miR-1208	CLIP-seq
MIRT2604671	hsa-miR-1322	CLIP-seq
MIRT2307186	hsa-miR-136	CLIP-seq
MIRT2604672	hsa-miR-1825	CLIP-seq
MIRT2307189	hsa-miR-186	CLIP-seq
MIRT2604673	hsa-miR-19a	CLIP-seq
MIRT2604674	hsa-miR-19b	CLIP-seq
MIRT2604675	hsa-miR-203	CLIP-seq
MIRT2604676	hsa-miR-2116	CLIP-seq
MIRT2604677	hsa-miR-299-3p	CLIP-seq
MIRT2307201	hsa-miR-3133	CLIP-seq
MIRT2307204	hsa-miR-3160-5p	CLIP-seq
MIRT2604678	hsa-miR-323b-3p	CLIP-seq
MIRT2604679	hsa-miR-3591-3p	CLIP-seq
MIRT2604680	hsa-miR-3613-3p	CLIP-seq
MIRT2604681	hsa-miR-3622b-5p	CLIP-seq
MIRT2604682	hsa-miR-3646	CLIP-seq
MIRT2604683	hsa-miR-3688-5p	CLIP-seq
MIRT2307210	hsa-miR-382	CLIP-seq
MIRT2604684	hsa-miR-3929	CLIP-seq
MIRT2604685	hsa-miR-409-3p	CLIP-seq
MIRT2604686	hsa-miR-4282	CLIP-seq
MIRT2604687	hsa-miR-4289	CLIP-seq
MIRT2604688	hsa-miR-4419b	CLIP-seq
MIRT2604689	hsa-miR-4420	CLIP-seq
MIRT2604690	hsa-miR-4422	CLIP-seq
MIRT2604691	hsa-miR-4423-5p	CLIP-seq
MIRT2604692	hsa-miR-4438	CLIP-seq
MIRT2307217	hsa-miR-4477a	CLIP-seq
MIRT2604693	hsa-miR-4478	CLIP-seq
MIRT2604694	hsa-miR-4491	CLIP-seq
MIRT2604695	hsa-miR-4640-5p	CLIP-seq
MIRT2432336	hsa-miR-4645-3p	CLIP-seq
MIRT2604696	hsa-miR-4657	CLIP-seq
MIRT2307222	hsa-miR-4659a-3p	CLIP-seq
MIRT2604697	hsa-miR-4659a-5p	CLIP-seq
MIRT2307223	hsa-miR-4659b-3p	CLIP-seq
MIRT2604698	hsa-miR-4659b-5p	CLIP-seq
MIRT2604699	hsa-miR-4704-5p	CLIP-seq
MIRT2307228	hsa-miR-4708-3p	CLIP-seq
MIRT2432337	hsa-miR-4725-5p	CLIP-seq
MIRT2604700	hsa-miR-4726-5p	CLIP-seq
MIRT2604701	hsa-miR-4731-5p	CLIP-seq
MIRT2604702	hsa-miR-4744	CLIP-seq
MIRT2432338	hsa-miR-4766-5p	CLIP-seq
MIRT2604703	hsa-miR-4776-3p	CLIP-seq
MIRT2604704	hsa-miR-4781-3p	CLIP-seq
MIRT2432339	hsa-miR-504	CLIP-seq
MIRT2604705	hsa-miR-512-3p	CLIP-seq
MIRT2604706	hsa-miR-526b	CLIP-seq
MIRT2604707	hsa-miR-539	CLIP-seq
MIRT2307237	hsa-miR-545	CLIP-seq
MIRT2307238	hsa-miR-548ae	CLIP-seq
MIRT2307239	hsa-miR-548aj	CLIP-seq
MIRT2307240	hsa-miR-548am	CLIP-seq
MIRT2307243	hsa-miR-548x	CLIP-seq
MIRT2604708	hsa-miR-578	CLIP-seq
MIRT2432340	hsa-miR-582-5p	CLIP-seq
MIRT2432335	hsa-miR-1178	CLIP-seq
MIRT2604670	hsa-miR-1208	CLIP-seq
MIRT2307186	hsa-miR-136	CLIP-seq
MIRT2604672	hsa-miR-1825	CLIP-seq
MIRT2307189	hsa-miR-186	CLIP-seq
MIRT2307201	hsa-miR-3133	CLIP-seq
MIRT2689105	hsa-miR-3148	CLIP-seq
MIRT2307204	hsa-miR-3160-5p	CLIP-seq
MIRT2604678	hsa-miR-323b-3p	CLIP-seq
MIRT2604679	hsa-miR-3591-3p	CLIP-seq
MIRT2604680	hsa-miR-3613-3p	CLIP-seq
MIRT2604681	hsa-miR-3622b-5p	CLIP-seq
MIRT2604684	hsa-miR-3929	CLIP-seq
MIRT2604686	hsa-miR-4282	CLIP-seq
MIRT2604688	hsa-miR-4419b	CLIP-seq
MIRT2604689	hsa-miR-4420	CLIP-seq
MIRT2604690	hsa-miR-4422	CLIP-seq
MIRT2604691	hsa-miR-4423-5p	CLIP-seq
MIRT2604692	hsa-miR-4438	CLIP-seq
MIRT2604693	hsa-miR-4478	CLIP-seq
MIRT2604695	hsa-miR-4640-5p	CLIP-seq
MIRT2432336	hsa-miR-4645-3p	CLIP-seq
MIRT2307222	hsa-miR-4659a-3p	CLIP-seq
MIRT2604697	hsa-miR-4659a-5p	CLIP-seq
MIRT2307223	hsa-miR-4659b-3p	CLIP-seq
MIRT2604698	hsa-miR-4659b-5p	CLIP-seq
MIRT2604699	hsa-miR-4704-5p	CLIP-seq
MIRT2432337	hsa-miR-4725-5p	CLIP-seq
MIRT2604700	hsa-miR-4726-5p	CLIP-seq
MIRT2604701	hsa-miR-4731-5p	CLIP-seq
MIRT2604702	hsa-miR-4744	CLIP-seq
MIRT2432338	hsa-miR-4766-5p	CLIP-seq
MIRT2604703	hsa-miR-4776-3p	CLIP-seq
MIRT2604704	hsa-miR-4781-3p	CLIP-seq
MIRT2432339	hsa-miR-504	CLIP-seq
MIRT2604705	hsa-miR-512-3p	CLIP-seq
MIRT2604706	hsa-miR-526b	CLIP-seq
MIRT2604707	hsa-miR-539	CLIP-seq
MIRT2307238	hsa-miR-548ae	CLIP-seq
MIRT2307239	hsa-miR-548aj	CLIP-seq
MIRT2307240	hsa-miR-548am	CLIP-seq
MIRT2307243	hsa-miR-548x	CLIP-seq
MIRT2604708	hsa-miR-578	CLIP-seq
MIRT2432340	hsa-miR-582-5p	CLIP-seq
MIRT2689106	hsa-miR-873	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IBA
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	8663237, 16263724, 16849327
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0005001	Function	Transmembrane receptor protein tyrosine phosphatase activity	NAS	9047348
GO:0005515	Function	Protein binding	IPI	15899872, 19167335, 21690299, 33961781
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	NAS	9047348
GO:0005911	Component	Cell-cell junction	IDA	8663237
GO:0005911	Component	Cell-cell junction	IEA
GO:0005912	Component	Adherens junction	IEA
GO:0006470	Process	Protein dephosphorylation	IDA	16263724
GO:0007155	Process	Cell adhesion	IMP	15899872
GO:0007165	Process	Signal transduction	IBA
GO:0007165	Process	Signal transduction	IDA	16849327
GO:0007179	Process	Transforming growth factor beta receptor signaling pathway	IDA	15899872
GO:0008013	Function	Beta-catenin binding	IEA
GO:0008013	Function	Beta-catenin binding	IPI	8663237
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	15899872, 18276111
GO:0009986	Component	Cell surface	IDA	18276111
GO:0010839	Process	Negative regulation of keratinocyte proliferation	IDA	16263724
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	9047348
GO:0016477	Process	Cell migration	IMP	15899872
GO:0016787	Function	Hydrolase activity	IEA
GO:0019901	Function	Protein kinase binding	IPI	15899872
GO:0030054	Component	Cell junction	IDA
GO:0030336	Process	Negative regulation of cell migration	IDA	18276111
GO:0030336	Process	Negative regulation of cell migration	IEA
GO:0031175	Process	Neuron projection development	IBA
GO:0031256	Component	Leading edge membrane	IDA	15899872
GO:0034394	Process	Protein localization to cell surface	IDA	18276111
GO:0034394	Process	Protein localization to cell surface	IEA
GO:0034614	Process	Cellular response to reactive oxygen species	IDA	16849327
GO:0034644	Process	Cellular response to UV	IDA	16849327
GO:0045295	Function	Gamma-catenin binding	IPI	8663237
GO:0045786	Process	Negative regulation of cell cycle	IDA	15899872
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	18276111
GO:0048041	Process	Focal adhesion assembly	IMP	15899872
GO:0070161	Component	Anchoring junction	IEA

MIM	HGNC	e!Ensembl
602545	9674	ENSG00000152894

Q15262

Protein name

Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)

Protein function

Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may b

PDB

2C7S , 8A1F

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00629	MAM	36 → 193	MAM domain, meprin/A5/mu	Domain
PF07679	I-set	197 → 288	Immunoglobulin I-set domain	Domain
PF00041	fn3	292 → 376	Fibronectin type III domain	Domain
PF00041	fn3	493 → 583	Fibronectin type III domain	Domain
PF18861	PTP_tm	621 → 778	Transmembrane domain of protein tyrosine phosphatase, receptor type J	Family
PF00102	Y_phosphatase	910 → 1140	Protein-tyrosine phosphatase	Domain
PF00102	Y_phosphatase	1200 → 1434	Protein-tyrosine phosphatase	Domain

Tissue specificity

TISSUE SPECIFICITY: High levels in lung, brain and colon; less in liver, pancreas, stomach, kidney, placenta and mammary carcinoma.

Sequence

MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHV
SAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNP
GTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYI
AIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPV
AQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQL
LGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYE
IRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRC
HTFNVTICYHYFRGHNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEE
TIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPV
AGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYE
GVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQVPVTYQN
AMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKE
TKTQCVRIATKAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKSKLA
KKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRYENHSATAES
SRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDSYGFKEEYESFFEGQSA
SWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQG
PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPDDTEVYGDFKVTCVEMEPLA
EYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVV
HCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILE
ACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRN
HDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDFWR
LVYDYGCTSIVMLNEVDLSQGCPQYWPEEGMLRYGPIQVECMSCSMDCDVINRIFRICNL
TRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGG
GRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLESS

Sequence length

1439

Interactions

View interactions

	Reactome
			EGFR downregulation

Show/Hide Unknown Diseases (17)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Clear cell carcinoma of kidney	Benign; Likely benign	rs61757812	RCV005910701
Colon adenocarcinoma	Benign; Likely benign	rs61757812	RCV005910698
Colorectal cancer	Benign; Likely benign	rs61757812	RCV005910703
Familial cancer of breast	Benign; Likely benign	rs61757812	RCV005910697
Gastric cancer	Benign; Likely benign	rs61757812	RCV005910705
Hereditary breast ovarian cancer syndrome	Uncertain significance	rs771714409	RCV001374547
Lung cancer	Benign; Likely benign	rs61757812	RCV005910710
Malignant lymphoma, large B-cell, diffuse	Benign; Likely benign	rs61757812	RCV005910702
Malignant tumor of esophagus	Benign; Likely benign	rs61757812	RCV005910700
Malignant tumor of urinary bladder	Benign; Likely benign	rs61757812	RCV005910699
Melanoma	Benign; Likely benign	rs61757812	RCV005910709
Ovarian serous cystadenocarcinoma	Benign; Likely benign	rs61757812	RCV005910706
Sarcoma	Benign; Likely benign	rs61757812	RCV005910704
sellar metastasis from primary bronchial carcinoid tumor	Uncertain significance	rs1482980901	RCV001251073
Thymoma	Benign; Likely benign	rs61757812	RCV005910707
Thyroid cancer, nonmedullary, 1	Benign; Likely benign	rs61757812	RCV005910708
Uterine corpus endometrial carcinoma	Benign; Likely benign	rs61757812	RCV005910711

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alzheimer Disease	Associate	28987514
Breast Neoplasms	Associate	23552869
Carcinogenesis	Associate	30838170, 36129915
Carcinoma Non Small Cell Lung	Inhibit	30838170
Celiac Disease	Associate	23820479, 36611909
Colorectal Neoplasms	Associate	23552869, 28100566, 36129915
Diabetes Mellitus	Associate	35986039
Diabetes Mellitus Type 1	Associate	28983737, 35986039
Disease	Associate	25052311
GATA2 Deficiency	Associate	25612622
Glioma	Associate	23696788
Hereditary leiomyomatosis and renal cell cancer	Associate	17720884
Hodgkin Disease	Associate	17720884
Lymphatic Metastasis	Inhibit	30838170
Lymphoma	Associate	23552869
Lymphoma Extranodal NK T Cell	Associate	25612622
Mental Disorders	Associate	28987514
Neoplasm Metastasis	Associate	20212451, 23552869, 30838170
Neoplasms	Associate	15899872, 23696788, 28987514, 31069394, 36129915
Neoplasms	Inhibit	18645192, 20212451, 23552869, 25612622, 26432421, 30838170, 30924770
Ovarian Neoplasms	Associate	31027318
Rhabdoid Tumor	Associate	20212451
Squamous Cell Carcinoma of Head and Neck	Associate	31069394

PTPRK (protein tyrosine phosphatase receptor type K)