Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID	578
Gene name	BCL2 antagonist/killer 1
Gene symbol	BAK1
Synonyms (NCBI Gene)	BAKBAK-LIKEBCL2L7CDN1
Chromosome	6
Chromosome location	6p21.31
Summary	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mito

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005350	hsa-miR-125a-5p	FlowLuciferase reporter assayqRT-PCRWestern blot	20616003
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assayqRT-PCRWestern blot	18056640
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assayqRT-PCRWestern blot	21823019
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assayqRT-PCRWestern blot	21823019
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assayqRT-PCRWestern blot	21823019
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	23497288
MIRT019714	hsa-miR-375	Microarray	20215506
MIRT002394	hsa-miR-125b-5p	Other	20729973
MIRT048976	hsa-miR-92a-3p	CLASH	23622248
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	23928699
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	23928699
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	23928699
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	23928699
MIRT568311	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT048976	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT568310	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT568309	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT568308	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT568307	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT568306	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT568305	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT568304	hsa-miR-1914-3p	PAR-CLIP	20371350
MIRT568302	hsa-miR-5194	PAR-CLIP	20371350
MIRT568303	hsa-miR-6738-5p	PAR-CLIP	20371350
MIRT568301	hsa-miR-4450	PAR-CLIP	20371350
MIRT568300	hsa-miR-4710	PAR-CLIP	20371350
MIRT568299	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568298	hsa-miR-3145-5p	PAR-CLIP	20371350
MIRT568311	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT048976	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT568310	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT568309	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT568308	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT568307	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT568306	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT568305	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT568304	hsa-miR-1914-3p	PAR-CLIP	20371350
MIRT568302	hsa-miR-5194	PAR-CLIP	20371350
MIRT568303	hsa-miR-6738-5p	PAR-CLIP	20371350
MIRT568301	hsa-miR-4450	PAR-CLIP	20371350
MIRT568300	hsa-miR-4710	PAR-CLIP	20371350
MIRT568299	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568298	hsa-miR-3145-5p	PAR-CLIP	20371350
MIRT526692	hsa-miR-1272	PAR-CLIP	22012620
MIRT526691	hsa-miR-1245b-3p	PAR-CLIP	22012620
MIRT526690	hsa-miR-4310	PAR-CLIP	22012620
MIRT526689	hsa-miR-7157-5p	PAR-CLIP	22012620
MIRT526688	hsa-miR-221-5p	PAR-CLIP	22012620
MIRT526687	hsa-miR-8073	PAR-CLIP	22012620
MIRT526686	hsa-miR-6787-3p	PAR-CLIP	22012620
MIRT526685	hsa-miR-4680-5p	PAR-CLIP	22012620
MIRT494572	hsa-miR-4506	PAR-CLIP	23592263
MIRT494571	hsa-miR-3622a-3p	PAR-CLIP	23592263
MIRT494570	hsa-miR-3622b-3p	PAR-CLIP	23592263
MIRT494569	hsa-miR-6765-3p	PAR-CLIP	23592263
MIRT494568	hsa-miR-20b-3p	PAR-CLIP	23592263
MIRT494567	hsa-miR-412-3p	PAR-CLIP	23592263
MIRT494566	hsa-miR-6754-3p	PAR-CLIP	23592263
MIRT494565	hsa-miR-4790-3p	PAR-CLIP	23592263
MIRT494564	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT494563	hsa-miR-6090	PAR-CLIP	23592263
MIRT494562	hsa-miR-4300	PAR-CLIP	23592263
MIRT494560	hsa-miR-5591-5p	PAR-CLIP	23592263
MIRT494561	hsa-miR-6726-5p	PAR-CLIP	23592263
MIRT494559	hsa-miR-920	PAR-CLIP	23592263
MIRT494558	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT494557	hsa-miR-6073	PAR-CLIP	23592263
MIRT494556	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT494555	hsa-miR-1257	PAR-CLIP	23592263
MIRT494554	hsa-miR-4425	PAR-CLIP	23592263
MIRT494553	hsa-miR-3606-5p	PAR-CLIP	23592263
MIRT494552	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT494551	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT494550	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT494549	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT494548	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT494547	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT494546	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT494545	hsa-miR-3689c	PAR-CLIP	23592263
MIRT494543	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT494544	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT494542	hsa-miR-3940-5p	PAR-CLIP	23592263
MIRT494541	hsa-miR-4507	PAR-CLIP	23592263
MIRT494540	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT002394	hsa-miR-125b-5p	Luciferase reporter assay	27158338
MIRT494564	hsa-miR-6827-5p	PAR-CLIP	26701625
MIRT494564	hsa-miR-6827-5p	PAR-CLIP	26701625
MIRT568311	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT048976	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT568310	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT568309	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT568308	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT568307	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT568306	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT568305	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT568304	hsa-miR-1914-3p	PAR-CLIP	20371350
MIRT568302	hsa-miR-5194	PAR-CLIP	20371350
MIRT568303	hsa-miR-6738-5p	PAR-CLIP	20371350
MIRT568301	hsa-miR-4450	PAR-CLIP	20371350
MIRT568300	hsa-miR-4710	PAR-CLIP	20371350
MIRT568299	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568298	hsa-miR-3145-5p	PAR-CLIP	20371350
MIRT568311	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT048976	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT568310	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT568309	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT568308	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT568307	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT568306	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT568305	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT568304	hsa-miR-1914-3p	PAR-CLIP	20371350
MIRT568302	hsa-miR-5194	PAR-CLIP	20371350
MIRT568303	hsa-miR-6738-5p	PAR-CLIP	20371350
MIRT568301	hsa-miR-4450	PAR-CLIP	20371350
MIRT568300	hsa-miR-4710	PAR-CLIP	20371350
MIRT568299	hsa-miR-6734-5p	PAR-CLIP	20371350
MIRT568298	hsa-miR-3145-5p	PAR-CLIP	20371350
MIRT526692	hsa-miR-1272	PAR-CLIP	22012620
MIRT526691	hsa-miR-1245b-3p	PAR-CLIP	22012620
MIRT526690	hsa-miR-4310	PAR-CLIP	22012620
MIRT526689	hsa-miR-7157-5p	PAR-CLIP	22012620
MIRT526688	hsa-miR-221-5p	PAR-CLIP	22012620
MIRT526687	hsa-miR-8073	PAR-CLIP	22012620
MIRT526686	hsa-miR-6787-3p	PAR-CLIP	22012620
MIRT526685	hsa-miR-4680-5p	PAR-CLIP	22012620
MIRT494572	hsa-miR-4506	PAR-CLIP	23592263
MIRT494571	hsa-miR-3622a-3p	PAR-CLIP	23592263
MIRT494570	hsa-miR-3622b-3p	PAR-CLIP	23592263
MIRT494569	hsa-miR-6765-3p	PAR-CLIP	23592263
MIRT494568	hsa-miR-20b-3p	PAR-CLIP	23592263
MIRT494567	hsa-miR-412-3p	PAR-CLIP	23592263
MIRT494566	hsa-miR-6754-3p	PAR-CLIP	23592263
MIRT494565	hsa-miR-4790-3p	PAR-CLIP	23592263
MIRT494564	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT494563	hsa-miR-6090	PAR-CLIP	23592263
MIRT494562	hsa-miR-4300	PAR-CLIP	23592263
MIRT494560	hsa-miR-5591-5p	PAR-CLIP	23592263
MIRT494561	hsa-miR-6726-5p	PAR-CLIP	23592263
MIRT494559	hsa-miR-920	PAR-CLIP	23592263
MIRT494558	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT494557	hsa-miR-6073	PAR-CLIP	23592263
MIRT494556	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT494555	hsa-miR-1257	PAR-CLIP	23592263
MIRT494554	hsa-miR-4425	PAR-CLIP	23592263
MIRT494553	hsa-miR-3606-5p	PAR-CLIP	23592263
MIRT494552	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT494551	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT494550	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT494549	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT494548	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT494547	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT494546	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT494545	hsa-miR-3689c	PAR-CLIP	23592263
MIRT494543	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT494544	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT494542	hsa-miR-3940-5p	PAR-CLIP	23592263
MIRT494541	hsa-miR-4507	PAR-CLIP	23592263
MIRT494540	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT815600	hsa-miR-1185	CLIP-seq
MIRT815601	hsa-miR-1224-3p	CLIP-seq
MIRT815602	hsa-miR-1227	CLIP-seq
MIRT815603	hsa-miR-125a-3p	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT815605	hsa-miR-1260	CLIP-seq
MIRT815606	hsa-miR-1260b	CLIP-seq
MIRT815607	hsa-miR-1280	CLIP-seq
MIRT815608	hsa-miR-1321	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT815610	hsa-miR-146a	CLIP-seq
MIRT815611	hsa-miR-146b-5p	CLIP-seq
MIRT815612	hsa-miR-1537	CLIP-seq
MIRT815613	hsa-miR-185	CLIP-seq
MIRT815614	hsa-miR-3126-5p	CLIP-seq
MIRT815615	hsa-miR-3150a-3p	CLIP-seq
MIRT815616	hsa-miR-3150b-3p	CLIP-seq
MIRT815617	hsa-miR-3166	CLIP-seq
MIRT815618	hsa-miR-3173-3p	CLIP-seq
MIRT815619	hsa-miR-3175	CLIP-seq
MIRT815620	hsa-miR-3192	CLIP-seq
MIRT815621	hsa-miR-326	CLIP-seq
MIRT815622	hsa-miR-330-5p	CLIP-seq
MIRT815623	hsa-miR-3614-3p	CLIP-seq
MIRT815624	hsa-miR-3679-5p	CLIP-seq
MIRT815625	hsa-miR-3925-5p	CLIP-seq
MIRT815626	hsa-miR-412	CLIP-seq
MIRT815627	hsa-miR-4257	CLIP-seq
MIRT815628	hsa-miR-4278	CLIP-seq
MIRT815629	hsa-miR-4305	CLIP-seq
MIRT815630	hsa-miR-4306	CLIP-seq
MIRT815631	hsa-miR-4314	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT815633	hsa-miR-4419a	CLIP-seq
MIRT815634	hsa-miR-4428	CLIP-seq
MIRT815635	hsa-miR-4434	CLIP-seq
MIRT815636	hsa-miR-451	CLIP-seq
MIRT815637	hsa-miR-4510	CLIP-seq
MIRT815638	hsa-miR-4511	CLIP-seq
MIRT815639	hsa-miR-4516	CLIP-seq
MIRT815640	hsa-miR-4521	CLIP-seq
MIRT815641	hsa-miR-4644	CLIP-seq
MIRT815642	hsa-miR-4646-5p	CLIP-seq
MIRT815643	hsa-miR-4651	CLIP-seq
MIRT815644	hsa-miR-4661-3p	CLIP-seq
MIRT815645	hsa-miR-4667-5p	CLIP-seq
MIRT815646	hsa-miR-4689	CLIP-seq
MIRT815647	hsa-miR-4700-5p	CLIP-seq
MIRT815648	hsa-miR-4713-5p	CLIP-seq
MIRT815649	hsa-miR-4716-3p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT815651	hsa-miR-4739	CLIP-seq
MIRT815652	hsa-miR-4751	CLIP-seq
MIRT815653	hsa-miR-4756-5p	CLIP-seq
MIRT815654	hsa-miR-4784	CLIP-seq
MIRT815655	hsa-miR-4795-5p	CLIP-seq
MIRT815656	hsa-miR-4802-5p	CLIP-seq
MIRT815657	hsa-miR-544b	CLIP-seq
MIRT815658	hsa-miR-552	CLIP-seq
MIRT815659	hsa-miR-608	CLIP-seq
MIRT815660	hsa-miR-637	CLIP-seq
MIRT815661	hsa-miR-647	CLIP-seq
MIRT815662	hsa-miR-769-5p	CLIP-seq
MIRT815663	hsa-miR-939	CLIP-seq
MIRT815603	hsa-miR-125a-3p	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT1941282	hsa-miR-1286	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT1941283	hsa-miR-24	CLIP-seq
MIRT815616	hsa-miR-3150b-3p	CLIP-seq
MIRT1941284	hsa-miR-3155	CLIP-seq
MIRT1941285	hsa-miR-3155b	CLIP-seq
MIRT1941286	hsa-miR-3176	CLIP-seq
MIRT1941287	hsa-miR-328	CLIP-seq
MIRT1941288	hsa-miR-3620	CLIP-seq
MIRT1941289	hsa-miR-3663-5p	CLIP-seq
MIRT1941290	hsa-miR-3922-3p	CLIP-seq
MIRT1941291	hsa-miR-3927	CLIP-seq
MIRT815629	hsa-miR-4305	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT1941292	hsa-miR-4324	CLIP-seq
MIRT1941293	hsa-miR-4468	CLIP-seq
MIRT1941294	hsa-miR-4527	CLIP-seq
MIRT1941295	hsa-miR-4650-3p	CLIP-seq
MIRT815646	hsa-miR-4689	CLIP-seq
MIRT1941296	hsa-miR-4693-3p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT1941297	hsa-miR-4757-5p	CLIP-seq
MIRT815654	hsa-miR-4784	CLIP-seq
MIRT1941298	hsa-miR-4796-5p	CLIP-seq
MIRT1941299	hsa-miR-484	CLIP-seq
MIRT1941300	hsa-miR-541	CLIP-seq
MIRT815657	hsa-miR-544b	CLIP-seq
MIRT815658	hsa-miR-552	CLIP-seq
MIRT1941301	hsa-miR-654-5p	CLIP-seq
MIRT1941302	hsa-miR-670	CLIP-seq
MIRT815662	hsa-miR-769-5p	CLIP-seq
MIRT815600	hsa-miR-1185	CLIP-seq
MIRT815603	hsa-miR-125a-3p	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT2180050	hsa-miR-1343	CLIP-seq
MIRT2180051	hsa-miR-1915	CLIP-seq
MIRT2180052	hsa-miR-2110	CLIP-seq
MIRT2180053	hsa-miR-296-5p	CLIP-seq
MIRT815616	hsa-miR-3150b-3p	CLIP-seq
MIRT2180054	hsa-miR-3180-5p	CLIP-seq
MIRT815623	hsa-miR-3614-3p	CLIP-seq
MIRT1941288	hsa-miR-3620	CLIP-seq
MIRT1941289	hsa-miR-3663-5p	CLIP-seq
MIRT815624	hsa-miR-3679-5p	CLIP-seq
MIRT2180055	hsa-miR-376c	CLIP-seq
MIRT1941291	hsa-miR-3927	CLIP-seq
MIRT815627	hsa-miR-4257	CLIP-seq
MIRT2180056	hsa-miR-4271	CLIP-seq
MIRT815628	hsa-miR-4278	CLIP-seq
MIRT2180057	hsa-miR-4286	CLIP-seq
MIRT2180058	hsa-miR-4292	CLIP-seq
MIRT2180059	hsa-miR-4301	CLIP-seq
MIRT815629	hsa-miR-4305	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT1941292	hsa-miR-4324	CLIP-seq
MIRT2180060	hsa-miR-4437	CLIP-seq
MIRT1941294	hsa-miR-4527	CLIP-seq
MIRT1941295	hsa-miR-4650-3p	CLIP-seq
MIRT815643	hsa-miR-4651	CLIP-seq
MIRT815645	hsa-miR-4667-5p	CLIP-seq
MIRT2180061	hsa-miR-4674	CLIP-seq
MIRT815646	hsa-miR-4689	CLIP-seq
MIRT1941296	hsa-miR-4693-3p	CLIP-seq
MIRT815647	hsa-miR-4700-5p	CLIP-seq
MIRT815649	hsa-miR-4716-3p	CLIP-seq
MIRT2180062	hsa-miR-4725-3p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT815654	hsa-miR-4784	CLIP-seq
MIRT2180063	hsa-miR-520a-5p	CLIP-seq
MIRT2180064	hsa-miR-525-5p	CLIP-seq
MIRT1941300	hsa-miR-541	CLIP-seq
MIRT815657	hsa-miR-544b	CLIP-seq
MIRT815658	hsa-miR-552	CLIP-seq
MIRT815659	hsa-miR-608	CLIP-seq
MIRT1941301	hsa-miR-654-5p	CLIP-seq
MIRT1941302	hsa-miR-670	CLIP-seq
MIRT815662	hsa-miR-769-5p	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT815617	hsa-miR-3166	CLIP-seq
MIRT815618	hsa-miR-3173-3p	CLIP-seq
MIRT1941289	hsa-miR-3663-5p	CLIP-seq
MIRT815634	hsa-miR-4428	CLIP-seq
MIRT2384739	hsa-miR-4462	CLIP-seq
MIRT815640	hsa-miR-4521	CLIP-seq
MIRT1941294	hsa-miR-4527	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT1941282	hsa-miR-1286	CLIP-seq
MIRT815608	hsa-miR-1321	CLIP-seq
MIRT2435619	hsa-miR-1909	CLIP-seq
MIRT2435620	hsa-miR-219-1-3p	CLIP-seq
MIRT2435621	hsa-miR-2682	CLIP-seq
MIRT2435622	hsa-miR-3132	CLIP-seq
MIRT2435623	hsa-miR-325	CLIP-seq
MIRT1941287	hsa-miR-328	CLIP-seq
MIRT2435624	hsa-miR-3714	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT1941292	hsa-miR-4324	CLIP-seq
MIRT815633	hsa-miR-4419a	CLIP-seq
MIRT2435625	hsa-miR-4451	CLIP-seq
MIRT1941293	hsa-miR-4468	CLIP-seq
MIRT2435626	hsa-miR-449c	CLIP-seq
MIRT815637	hsa-miR-4510	CLIP-seq
MIRT1941296	hsa-miR-4693-3p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT815651	hsa-miR-4739	CLIP-seq
MIRT2435627	hsa-miR-4743	CLIP-seq
MIRT815653	hsa-miR-4756-5p	CLIP-seq
MIRT2435628	hsa-miR-518a-5p	CLIP-seq
MIRT2435629	hsa-miR-527	CLIP-seq
MIRT2435630	hsa-miR-548an	CLIP-seq
MIRT1941302	hsa-miR-670	CLIP-seq
MIRT2483427	hsa-miR-122	CLIP-seq
MIRT815602	hsa-miR-1227	CLIP-seq
MIRT815603	hsa-miR-125a-3p	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT2483428	hsa-miR-1275	CLIP-seq
MIRT2483429	hsa-miR-128	CLIP-seq
MIRT2483430	hsa-miR-1297	CLIP-seq
MIRT815608	hsa-miR-1321	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT2483431	hsa-miR-1470	CLIP-seq
MIRT2435619	hsa-miR-1909	CLIP-seq
MIRT2180051	hsa-miR-1915	CLIP-seq
MIRT2435621	hsa-miR-2682	CLIP-seq
MIRT2483432	hsa-miR-26a	CLIP-seq
MIRT2483433	hsa-miR-26b	CLIP-seq
MIRT2483434	hsa-miR-27a	CLIP-seq
MIRT2483435	hsa-miR-27b	CLIP-seq
MIRT815614	hsa-miR-3126-5p	CLIP-seq
MIRT2435622	hsa-miR-3132	CLIP-seq
MIRT2483436	hsa-miR-3135b	CLIP-seq
MIRT2483437	hsa-miR-3144-5p	CLIP-seq
MIRT815616	hsa-miR-3150b-3p	CLIP-seq
MIRT2483438	hsa-miR-3182	CLIP-seq
MIRT2483439	hsa-miR-3184	CLIP-seq
MIRT2483440	hsa-miR-320a	CLIP-seq
MIRT2483441	hsa-miR-320b	CLIP-seq
MIRT2483442	hsa-miR-320c	CLIP-seq
MIRT2483443	hsa-miR-320d	CLIP-seq
MIRT2483444	hsa-miR-320e	CLIP-seq
MIRT2483445	hsa-miR-3606	CLIP-seq
MIRT815623	hsa-miR-3614-3p	CLIP-seq
MIRT1941288	hsa-miR-3620	CLIP-seq
MIRT1941289	hsa-miR-3663-5p	CLIP-seq
MIRT2483446	hsa-miR-3667-5p	CLIP-seq
MIRT2483447	hsa-miR-3686	CLIP-seq
MIRT2435624	hsa-miR-3714	CLIP-seq
MIRT2483448	hsa-miR-3922-5p	CLIP-seq
MIRT2483449	hsa-miR-3929	CLIP-seq
MIRT815626	hsa-miR-412	CLIP-seq
MIRT2483450	hsa-miR-4290	CLIP-seq
MIRT815629	hsa-miR-4305	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT1941292	hsa-miR-4324	CLIP-seq
MIRT815633	hsa-miR-4419a	CLIP-seq
MIRT2483451	hsa-miR-4419b	CLIP-seq
MIRT2483452	hsa-miR-4429	CLIP-seq
MIRT2483453	hsa-miR-4447	CLIP-seq
MIRT2435625	hsa-miR-4451	CLIP-seq
MIRT2384739	hsa-miR-4462	CLIP-seq
MIRT2483454	hsa-miR-4465	CLIP-seq
MIRT2483455	hsa-miR-4472	CLIP-seq
MIRT2483456	hsa-miR-4478	CLIP-seq
MIRT2435626	hsa-miR-449c	CLIP-seq
MIRT815637	hsa-miR-4510	CLIP-seq
MIRT2483457	hsa-miR-4525	CLIP-seq
MIRT1941294	hsa-miR-4527	CLIP-seq
MIRT2483458	hsa-miR-4639-5p	CLIP-seq
MIRT815644	hsa-miR-4661-3p	CLIP-seq
MIRT2483459	hsa-miR-4665-5p	CLIP-seq
MIRT2483460	hsa-miR-4671-5p	CLIP-seq
MIRT815646	hsa-miR-4689	CLIP-seq
MIRT1941296	hsa-miR-4693-3p	CLIP-seq
MIRT2483461	hsa-miR-4723-5p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT815651	hsa-miR-4739	CLIP-seq
MIRT2435627	hsa-miR-4743	CLIP-seq
MIRT815653	hsa-miR-4756-5p	CLIP-seq
MIRT815654	hsa-miR-4784	CLIP-seq
MIRT2483462	hsa-miR-4797-5p	CLIP-seq
MIRT815656	hsa-miR-4802-5p	CLIP-seq
MIRT2483463	hsa-miR-513a-5p	CLIP-seq
MIRT2435628	hsa-miR-518a-5p	CLIP-seq
MIRT2483464	hsa-miR-526b	CLIP-seq
MIRT2435629	hsa-miR-527	CLIP-seq
MIRT815657	hsa-miR-544b	CLIP-seq
MIRT2435630	hsa-miR-548an	CLIP-seq
MIRT815658	hsa-miR-552	CLIP-seq
MIRT2483465	hsa-miR-625	CLIP-seq
MIRT2483466	hsa-miR-645	CLIP-seq
MIRT1941302	hsa-miR-670	CLIP-seq
MIRT815662	hsa-miR-769-5p	CLIP-seq
MIRT2483427	hsa-miR-122	CLIP-seq
MIRT815601	hsa-miR-1224-3p	CLIP-seq
MIRT815602	hsa-miR-1227	CLIP-seq
MIRT815603	hsa-miR-125a-3p	CLIP-seq
MIRT815604	hsa-miR-125b	CLIP-seq
MIRT815605	hsa-miR-1260	CLIP-seq
MIRT815606	hsa-miR-1260b	CLIP-seq
MIRT2483428	hsa-miR-1275	CLIP-seq
MIRT2483429	hsa-miR-128	CLIP-seq
MIRT815607	hsa-miR-1280	CLIP-seq
MIRT1941282	hsa-miR-1286	CLIP-seq
MIRT2483430	hsa-miR-1297	CLIP-seq
MIRT815608	hsa-miR-1321	CLIP-seq
MIRT815609	hsa-miR-1324	CLIP-seq
MIRT2483431	hsa-miR-1470	CLIP-seq
MIRT2435619	hsa-miR-1909	CLIP-seq
MIRT2180051	hsa-miR-1915	CLIP-seq
MIRT2435620	hsa-miR-219-1-3p	CLIP-seq
MIRT2435621	hsa-miR-2682	CLIP-seq
MIRT2483432	hsa-miR-26a	CLIP-seq
MIRT2483433	hsa-miR-26b	CLIP-seq
MIRT2483434	hsa-miR-27a	CLIP-seq
MIRT2483435	hsa-miR-27b	CLIP-seq
MIRT815614	hsa-miR-3126-5p	CLIP-seq
MIRT2435622	hsa-miR-3132	CLIP-seq
MIRT2483436	hsa-miR-3135b	CLIP-seq
MIRT2483437	hsa-miR-3144-5p	CLIP-seq
MIRT815616	hsa-miR-3150b-3p	CLIP-seq
MIRT2483438	hsa-miR-3182	CLIP-seq
MIRT2483439	hsa-miR-3184	CLIP-seq
MIRT2483440	hsa-miR-320a	CLIP-seq
MIRT2483441	hsa-miR-320b	CLIP-seq
MIRT2483442	hsa-miR-320c	CLIP-seq
MIRT2483443	hsa-miR-320d	CLIP-seq
MIRT2483444	hsa-miR-320e	CLIP-seq
MIRT2483445	hsa-miR-3606	CLIP-seq
MIRT815623	hsa-miR-3614-3p	CLIP-seq
MIRT1941288	hsa-miR-3620	CLIP-seq
MIRT1941289	hsa-miR-3663-5p	CLIP-seq
MIRT2483447	hsa-miR-3686	CLIP-seq
MIRT2435624	hsa-miR-3714	CLIP-seq
MIRT2483448	hsa-miR-3922-5p	CLIP-seq
MIRT815626	hsa-miR-412	CLIP-seq
MIRT2483450	hsa-miR-4290	CLIP-seq
MIRT815629	hsa-miR-4305	CLIP-seq
MIRT815632	hsa-miR-4319	CLIP-seq
MIRT1941292	hsa-miR-4324	CLIP-seq
MIRT815633	hsa-miR-4419a	CLIP-seq
MIRT2483452	hsa-miR-4429	CLIP-seq
MIRT2483453	hsa-miR-4447	CLIP-seq
MIRT2435625	hsa-miR-4451	CLIP-seq
MIRT2384739	hsa-miR-4462	CLIP-seq
MIRT2483454	hsa-miR-4465	CLIP-seq
MIRT1941293	hsa-miR-4468	CLIP-seq
MIRT2483455	hsa-miR-4472	CLIP-seq
MIRT2435626	hsa-miR-449c	CLIP-seq
MIRT815637	hsa-miR-4510	CLIP-seq
MIRT2483457	hsa-miR-4525	CLIP-seq
MIRT1941294	hsa-miR-4527	CLIP-seq
MIRT2483458	hsa-miR-4639-5p	CLIP-seq
MIRT815644	hsa-miR-4661-3p	CLIP-seq
MIRT2483459	hsa-miR-4665-5p	CLIP-seq
MIRT2483460	hsa-miR-4671-5p	CLIP-seq
MIRT815646	hsa-miR-4689	CLIP-seq
MIRT1941296	hsa-miR-4693-3p	CLIP-seq
MIRT2483461	hsa-miR-4723-5p	CLIP-seq
MIRT815650	hsa-miR-4732-3p	CLIP-seq
MIRT815651	hsa-miR-4739	CLIP-seq
MIRT2435627	hsa-miR-4743	CLIP-seq
MIRT815653	hsa-miR-4756-5p	CLIP-seq
MIRT815654	hsa-miR-4784	CLIP-seq
MIRT1941298	hsa-miR-4796-5p	CLIP-seq
MIRT2483462	hsa-miR-4797-5p	CLIP-seq
MIRT815656	hsa-miR-4802-5p	CLIP-seq
MIRT2483463	hsa-miR-513a-5p	CLIP-seq
MIRT2435628	hsa-miR-518a-5p	CLIP-seq
MIRT2483464	hsa-miR-526b	CLIP-seq
MIRT2435629	hsa-miR-527	CLIP-seq
MIRT815657	hsa-miR-544b	CLIP-seq
MIRT2435630	hsa-miR-548an	CLIP-seq
MIRT815658	hsa-miR-552	CLIP-seq
MIRT2483465	hsa-miR-625	CLIP-seq
MIRT1941302	hsa-miR-670	CLIP-seq
MIRT815662	hsa-miR-769-5p	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
WWTR1	Activation	22470139

111

Show/Hide all (111)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001776	Process	Leukocyte homeostasis	IEA
GO:0001782	Process	B cell homeostasis	IEA
GO:0001783	Process	B cell apoptotic process	IEA
GO:0001836	Process	Release of cytochrome c from mitochondria	IBA
GO:0001836	Process	Release of cytochrome c from mitochondria	IDA	9843949, 16199525
GO:0001836	Process	Release of cytochrome c from mitochondria	IEA
GO:0001836	Process	Release of cytochrome c from mitochondria	IGI	21041309
GO:0001974	Process	Blood vessel remodeling	IEA
GO:0002262	Process	Myeloid cell homeostasis	IEA
GO:0002352	Process	B cell negative selection	IEA
GO:0005515	Function	Protein binding	IPI	9027312, 9111042, 9463381, 9843949, 10381623, 10950869, 11571294, 12624108, 14596824, 15901672, 16189514, 16439990, 17097560, 17289999, 17446862, 17606912, 18040043, 19060904, 19968986, 20023629, 21036904, 21132008, 22516262, 23055042, 23604079, 23680104, 23782464, 25416956, 2600468
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	9843949
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IBA
GO:0005741	Component	Mitochondrial outer membrane	IDA	22006182
GO:0005741	Component	Mitochondrial outer membrane	IDA	29531808, 32929280
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005741	Component	Mitochondrial outer membrane	ISS
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IEA
GO:0006915	Process	Apoptotic process	IDA	23028632
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	NAS	7715731
GO:0008053	Process	Mitochondrial fusion	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0008630	Process	Intrinsic apoptotic signaling pathway in response to DNA damage	IBA
GO:0008630	Process	Intrinsic apoptotic signaling pathway in response to DNA damage	IEA
GO:0009410	Process	Response to xenobiotic stimulus	IEA
GO:0009620	Process	Response to fungus	IEA
GO:0010046	Process	Response to mycotoxin	IEA
GO:0010225	Process	Response to UV-C	IEA
GO:0010248	Process	Establishment or maintenance of transmembrane electrochemical gradient	IDA	9843949
GO:0010332	Process	Response to gamma radiation	IEA
GO:0010524	Process	Positive regulation of calcium ion transport into cytosol	IEA
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0015267	Function	Channel activity	IBA
GO:0015288	Function	Porin activity	IDA	22006182
GO:0016020	Component	Membrane	IEA
GO:0031018	Process	Endocrine pancreas development	IEA
GO:0031072	Function	Heat shock protein binding	IEA
GO:0031100	Process	Animal organ regeneration	IEA
GO:0031334	Process	Positive regulation of protein-containing complex assembly	IDA	9111042
GO:0031966	Component	Mitochondrial membrane	IEA
GO:0032469	Process	Endoplasmic reticulum calcium ion homeostasis	IEA
GO:0032469	Process	Endoplasmic reticulum calcium ion homeostasis	TAS	18309324
GO:0032471	Process	Negative regulation of endoplasmic reticulum calcium ion concentration	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034620	Process	Cellular response to unfolded protein	TAS	22013210
GO:0034644	Process	Cellular response to UV	IEA
GO:0034644	Process	Cellular response to UV	IMP	15901672
GO:0034644	Process	Cellular response to UV	ISS
GO:0035108	Process	Limb morphogenesis	IEA
GO:0042542	Process	Response to hydrogen peroxide	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	10950869, 15901672, 16439990, 17024184, 17446862, 21041309, 23782464, 32929280
GO:0042803	Function	Protein homodimerization activity	IDA	23028632
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IBA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IMP	17289999
GO:0043065	Process	Positive regulation of apoptotic process	ISS
GO:0044325	Function	Transmembrane transporter binding	IPI	25296756
GO:0044346	Process	Fibroblast apoptotic process	IEA
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0045471	Process	Response to ethanol	IEA
GO:0045862	Process	Positive regulation of proteolysis	IDA	18387192
GO:0046872	Function	Metal ion binding	IEA
GO:0046902	Process	Regulation of mitochondrial membrane permeability	IDA	9843949, 21041309
GO:0046930	Component	Pore complex	IDA	9843949
GO:0046982	Function	Protein heterodimerization activity	IPI	10837489
GO:0048597	Process	Post-embryonic camera-type eye morphogenesis	IEA
GO:0048872	Process	Homeostasis of number of cells	IEA
GO:0050673	Process	Epithelial cell proliferation	IEA
GO:0051049	Process	Regulation of transport	IEA
GO:0051087	Function	Protein-folding chaperone binding	IEA
GO:0051400	Function	BH domain binding	IEA
GO:0051649	Process	Establishment of localization in cell	IEA
GO:0051726	Process	Regulation of cell cycle	IEA
GO:0051881	Process	Regulation of mitochondrial membrane potential	IDA	9843949
GO:0060068	Process	Vagina development	IEA
GO:0060402	Process	Calcium ion transport into cytosol	IEA
GO:0065008	Process	Regulation of biological quality	IEA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IEA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IEA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	TAS	22934019
GO:0070242	Process	Thymocyte apoptotic process	IEA
GO:0071260	Process	Cellular response to mechanical stimulus	IEP	19593445
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	IEA
GO:0090200	Process	Positive regulation of release of cytochrome c from mitochondria	NAS	32929280
GO:0090201	Process	Negative regulation of release of cytochrome c from mitochondria	IDA	15901672
GO:0097136	Component	Bcl-2 family protein complex	IDA	21041309
GO:0097136	Component	Bcl-2 family protein complex	IPI	22515821
GO:0097145	Component	BAK complex	IDA	10950869, 17024184, 23028632
GO:0097145	Component	BAK complex	IEA
GO:0097145	Component	BAK complex	IPI	32929280
GO:0097190	Process	Apoptotic signaling pathway	IMP	15901672
GO:0097192	Process	Extrinsic apoptotic signaling pathway in absence of ligand	IBA
GO:0097192	Process	Extrinsic apoptotic signaling pathway in absence of ligand	IEA
GO:0097193	Process	Intrinsic apoptotic signaling pathway	IC	10206961
GO:0097193	Process	Intrinsic apoptotic signaling pathway	IDA	22006182
GO:0097193	Process	Intrinsic apoptotic signaling pathway	IMP	15565177
GO:1901029	Process	Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IDA	15901672
GO:1901030	Process	Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	NAS	32929280
GO:1902262	Process	Apoptotic process involved in blood vessel morphogenesis	IEA
GO:1902531	Process	Regulation of intracellular signal transduction	IEA
GO:1903896	Process	Positive regulation of IRE1-mediated unfolded protein response	TAS	22013210
GO:2001233	Process	Regulation of apoptotic signaling pathway	IEA

MIM	HGNC	e!Ensembl
600516	949	ENSG00000030110

Q16611

Protein name

Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)

Protein function

Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytos

PDB

1BXL , 2IMS , 2IMT , 2JBY , 2JCN , 2LP8 , 2M5B , 2XPX , 2YV6 , 3I1H , 3QBR , 4D2L , 4U2U , 4U2V , 4UF1 , 5AJK , 5FMI , 5FMK , 5VWV , 5VWW , 5VWX , 5VWY , 5VWZ , 5VX0 , 5VX1 , 6ODH , 6UXM , 6UXN , 6UXO , 6UXP , 6UXQ , 6UXR , 7K02 , 7LK4 , 7M5A , 7M5B , 7OFM , 7OFO , 8CZF , 8CZG , 8CZH , 8GSV , 8IGC , 8IVB , 8SRX , 8SRY , 8UKY , 8Y1Y , 8Y1Z

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00452	Bcl-2	78 → 177	Apoptosis regulator proteins, Bcl-2 family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.

Sequence

MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEM
VTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFE
SGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAA
LNLGNGPILNVLVVLGVVLLGQFVVRRFFKS

Sequence length

211

Interactions

View interactions

	KEGG		Reactome
	Platinum drug resistance Protein processing in endoplasmic reticulum Apoptosis Apoptosis - multiple species Pathways of neurodegeneration - multiple diseases Pathogenic Escherichia coli infection Salmonella infection Hepatitis C Measles Human cytomegalovirus infection Influenza A Human papillomavirus infection Kaposi sarcoma-associated herpesvirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Pathways in cancer Transcriptional misregulation in cancer Viral carcinogenesis MicroRNAs in cancer Colorectal cancer Pancreatic cancer Endometrial cancer Glioma Thyroid cancer Basal cell carcinoma Melanoma Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer Breast cancer Hepatocellular carcinoma Gastric cancer		Activation and oligomerization of BAK protein Release of apoptotic factors from the mitochondria

BAK1 (BCL2 antagonist/killer 1)