Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
57610
Gene name Gene Name - the full gene name approved by the HGNC.
RAN binding protein 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RANBP10
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q22.1
Summary Summary of gene provided in NCBI Entrez Gene.
RAN is a small GTPase involved in the assembly of microtubules to form mitotic spindles. The protein encoded by this gene is a cytoplasmic guanine nucleotide exchange factor (GEF) that binds beta-tubulin and has GEF activity toward RAN. The encoded protei
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022988 hsa-miR-124-3p Microarray 18668037
MIRT046829 hsa-miR-222-3p CLASH 23622248
MIRT046500 hsa-miR-15b-5p CLASH 23622248
MIRT045170 hsa-miR-186-5p CLASH 23622248
MIRT039744 hsa-miR-615-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000151 Component Ubiquitin ligase complex IDA 29911972
GO:0005515 Function Protein binding IPI 20580816, 32296183
GO:0005634 Component Nucleus IEA
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614031 29285 ENSG00000141084
Protein
UniProt ID Q6VN20
Protein name Ran-binding protein 10 (RanBP10)
Protein function May act as an adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination a
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00622 SPRY 102 220 SPRY domain Family
PF08513 LisH 256 279 LisH Domain
PF10607 CLTH 291 602 CTLH/CRA C-terminal to LisH motif domain Domain
Tissue specificity TISSUE SPECIFICITY: Broadly expressed, with highest levels in skeletal muscle. {ECO:0000269|PubMed:14684163}.
Sequence
Sequence length 620
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    MET activates RAS signaling
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Gastric cancer Hereditary Diffuse Gastric Cancer rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802
View all (244 more)
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