DIP2B (disco interacting protein 2 homolog B)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57609 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Disco interacting protein 2 homolog B |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DIP2B |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q13.12 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q9P265 | ||||||||||||||||||||
| Protein name | Disco-interacting protein 2 homolog B (DIP2 homolog B) | ||||||||||||||||||||
| Protein function | Negatively regulates axonal outgrowth and is essential for normal synaptic transmission. Not required for regulation of axon polarity. Promotes acetylation of alpha-tubulin. | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Moderately expressed in adult brain, placenta, skeletal muscle, heart, kidney, pancreas, lung, spleen and colon. Expression was weaker in adult liver, kidney, spleen, and ovary, and in fetal brain and liver. In the brain, it is express | ||||||||||||||||||||
| Sequence | |||||||||||||||||||||
| Sequence length | 1576 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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