NLN (neurolysin)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57486 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Neurolysin |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NLN |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AGTBP, EP24.16, MEP, MOP |
Chromosome
Chromosome number
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5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q12.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the n |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9BYT8 | ||||||||||
Protein name | Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase) | ||||||||||
Protein function | Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity). Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By si | ||||||||||
PDB | 5LUZ , 5LV0 , 8VJU , 8VJV , 8VJW , 8VJX , 8VJY | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 704 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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