PTAFR (platelet activating factor receptor)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
5724 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Platelet activating factor receptor |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
PTAFR |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
PAFR |
|
Chromosome
Chromosome number
|
1 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1p35.3 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that play |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
| Transcription factors | |||||||||||||
|
|||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||
| UniProt ID | P25105 | ||||||||||
| Protein name | Platelet-activating factor receptor (PAF-R) (PAFr) | ||||||||||
| Protein function | Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinosito | ||||||||||
| PDB | 5ZKP , 5ZKQ , 8XYD | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. {ECO:0000269|PubMed:1281995, ECO:0000269|PubMed:1656963, ECO:0000269|PubMed:1657923}. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 342 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|