PTAFR (platelet activating factor receptor)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 5724 |
| Gene name | Platelet activating factor receptor |
| Gene symbol | PTAFR |
| Synonyms (NCBI Gene) |
PAFR
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| Chromosome | 1 |
| Chromosome location | 1p35.3 |
| Summary | This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that play |
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miRNA
miRNA information provided by mirtarbase database.
353
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
3
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P25105 | ||||||||||
| Protein name | Platelet-activating factor receptor (PAF-R) (PAFr) | ||||||||||
| Protein function | Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinosito | ||||||||||
| PDB | 5ZKP , 5ZKQ , 8XYD | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. {ECO:0000269|PubMed:1281995, ECO:0000269|PubMed:1656963, ECO:0000269|PubMed:1657923}. | ||||||||||
| Sequence |
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| Sequence length | 342 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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