Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	56980
Gene name	PR/SET domain 10
Gene symbol	PRDM10
Synonyms (NCBI Gene)	BHD2PFM7TRIS
Chromosome	11
Chromosome location	11q24.3
Summary	The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell diff

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Show/Hide all (201)

miRTarBase ID	miRNA	Experiments	Reference
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	19536157
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT713839	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT713838	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT700631	hsa-miR-1178-5p	HITS-CLIP	23313552
MIRT700630	hsa-miR-1182	HITS-CLIP	23313552
MIRT700629	hsa-miR-194-3p	HITS-CLIP	23313552
MIRT700628	hsa-miR-1250-3p	HITS-CLIP	23313552
MIRT700627	hsa-miR-5191	HITS-CLIP	23313552
MIRT700626	hsa-miR-505-3p	HITS-CLIP	23313552
MIRT700625	hsa-miR-374b-3p	HITS-CLIP	23313552
MIRT700624	hsa-miR-1305	HITS-CLIP	23313552
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT666816	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT058532	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT646468	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT646467	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT646466	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT646465	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT646464	hsa-miR-3671	HITS-CLIP	23824327
MIRT646463	hsa-miR-579-3p	HITS-CLIP	23824327
MIRT646462	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT646461	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT646460	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT646459	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT646458	hsa-miR-607	HITS-CLIP	23824327
MIRT646457	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT544464	hsa-miR-3185	PAR-CLIP	21572407
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	19536157
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT713839	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT713838	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT700631	hsa-miR-1178-5p	HITS-CLIP	23313552
MIRT700630	hsa-miR-1182	HITS-CLIP	23313552
MIRT700629	hsa-miR-194-3p	HITS-CLIP	23313552
MIRT700628	hsa-miR-1250-3p	HITS-CLIP	23313552
MIRT700627	hsa-miR-5191	HITS-CLIP	23313552
MIRT700626	hsa-miR-505-3p	HITS-CLIP	23313552
MIRT700625	hsa-miR-374b-3p	HITS-CLIP	23313552
MIRT700624	hsa-miR-1305	HITS-CLIP	23313552
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT666816	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT058532	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT646468	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT646467	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT646466	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT646465	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT646464	hsa-miR-3671	HITS-CLIP	23824327
MIRT646463	hsa-miR-579-3p	HITS-CLIP	23824327
MIRT646462	hsa-miR-664b-3p	HITS-CLIP	23824327
MIRT646461	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT646460	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT646459	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT646458	hsa-miR-607	HITS-CLIP	23824327
MIRT646457	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT638410	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT619476	hsa-miR-4282	HITS-CLIP	23824327
MIRT619475	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT619474	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT619473	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT619472	hsa-miR-6826-5p	HITS-CLIP	23824327
MIRT619471	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT619470	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT619469	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT544464	hsa-miR-3185	PAR-CLIP	21572407
MIRT1259863	hsa-miR-1237	CLIP-seq
MIRT1259864	hsa-miR-1248	CLIP-seq
MIRT1259865	hsa-miR-140-3p	CLIP-seq
MIRT1259866	hsa-miR-3156-5p	CLIP-seq
MIRT1259867	hsa-miR-331-3p	CLIP-seq
MIRT1259868	hsa-miR-3612	CLIP-seq
MIRT1259869	hsa-miR-3679-3p	CLIP-seq
MIRT1259870	hsa-miR-3689a-3p	CLIP-seq
MIRT1259871	hsa-miR-3689c	CLIP-seq
MIRT1259872	hsa-miR-4728-5p	CLIP-seq
MIRT1259873	hsa-miR-4766-5p	CLIP-seq
MIRT1259874	hsa-miR-650	CLIP-seq
MIRT1259875	hsa-miR-1236	CLIP-seq
MIRT1259876	hsa-miR-1243	CLIP-seq
MIRT1259877	hsa-miR-1276	CLIP-seq
MIRT1259878	hsa-miR-1290	CLIP-seq
MIRT1259879	hsa-miR-3167	CLIP-seq
MIRT1259880	hsa-miR-4463	CLIP-seq
MIRT1259881	hsa-miR-4659a-3p	CLIP-seq
MIRT1259882	hsa-miR-4659b-3p	CLIP-seq
MIRT1259883	hsa-miR-520d-5p	CLIP-seq
MIRT1259884	hsa-miR-524-5p	CLIP-seq
MIRT1259885	hsa-miR-548u	CLIP-seq
MIRT1259886	hsa-miR-579	CLIP-seq
MIRT1259887	hsa-miR-600	CLIP-seq
MIRT1259888	hsa-miR-664	CLIP-seq
MIRT1259889	hsa-miR-876-5p	CLIP-seq
MIRT1259890	hsa-miR-106a	CLIP-seq
MIRT1259891	hsa-miR-106b	CLIP-seq
MIRT1259892	hsa-miR-142-5p	CLIP-seq
MIRT1259893	hsa-miR-155	CLIP-seq
MIRT1259894	hsa-miR-17	CLIP-seq
MIRT1259895	hsa-miR-20a	CLIP-seq
MIRT1259896	hsa-miR-20b	CLIP-seq
MIRT1259897	hsa-miR-221	CLIP-seq
MIRT1259898	hsa-miR-222	CLIP-seq
MIRT1259899	hsa-miR-3129-3p	CLIP-seq
MIRT1259900	hsa-miR-338-5p	CLIP-seq
MIRT1259901	hsa-miR-3609	CLIP-seq
MIRT1259902	hsa-miR-365	CLIP-seq
MIRT1259903	hsa-miR-4330	CLIP-seq
MIRT1259904	hsa-miR-4643	CLIP-seq
MIRT1259905	hsa-miR-466	CLIP-seq
MIRT1259906	hsa-miR-4666-5p	CLIP-seq
MIRT1259907	hsa-miR-4717-5p	CLIP-seq
MIRT1259908	hsa-miR-4789-3p	CLIP-seq
MIRT1259909	hsa-miR-4794	CLIP-seq
MIRT1259910	hsa-miR-4796-3p	CLIP-seq
MIRT1259911	hsa-miR-519d	CLIP-seq
MIRT1259912	hsa-miR-548ah	CLIP-seq
MIRT1259913	hsa-miR-892b	CLIP-seq
MIRT1259914	hsa-miR-93	CLIP-seq
MIRT1259900	hsa-miR-338-5p	CLIP-seq
MIRT2076570	hsa-miR-4711-3p	CLIP-seq
MIRT1259886	hsa-miR-579	CLIP-seq
MIRT1259892	hsa-miR-142-5p	CLIP-seq
MIRT1259897	hsa-miR-221	CLIP-seq
MIRT1259898	hsa-miR-222	CLIP-seq
MIRT1259900	hsa-miR-338-5p	CLIP-seq
MIRT2303178	hsa-miR-4267	CLIP-seq
MIRT2303179	hsa-miR-4318	CLIP-seq
MIRT1259907	hsa-miR-4717-5p	CLIP-seq
MIRT1259909	hsa-miR-4794	CLIP-seq
MIRT1259913	hsa-miR-892b	CLIP-seq
MIRT2303180	hsa-miR-9	CLIP-seq
MIRT2599859	hsa-miR-1269	CLIP-seq
MIRT2599860	hsa-miR-1269b	CLIP-seq
MIRT2599861	hsa-miR-1288	CLIP-seq
MIRT2599862	hsa-miR-139-5p	CLIP-seq
MIRT2599863	hsa-miR-3618	CLIP-seq
MIRT2599864	hsa-miR-3654	CLIP-seq
MIRT2599865	hsa-miR-378	CLIP-seq
MIRT2599866	hsa-miR-378b	CLIP-seq
MIRT2599867	hsa-miR-378c	CLIP-seq
MIRT2599868	hsa-miR-378d	CLIP-seq
MIRT2599869	hsa-miR-378e	CLIP-seq
MIRT2599870	hsa-miR-378f	CLIP-seq
MIRT2599871	hsa-miR-378h	CLIP-seq
MIRT2599872	hsa-miR-378i	CLIP-seq
MIRT2599873	hsa-miR-422a	CLIP-seq
MIRT2599874	hsa-miR-4515	CLIP-seq
MIRT2599875	hsa-miR-4740-5p	CLIP-seq
MIRT1259909	hsa-miR-4794	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IDA	36440963
GO:0000785	Component	Chromatin	IDA	31143550
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	36440963
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	36440963
GO:0005634	Component	Nucleus	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0017053	Component	Transcription repressor complex	IDA	31143550
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	36440963
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	31143550
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
618319	13995	ENSG00000170325

Q9NQV6

Protein name

PR domain zinc finger protein 10 (PR domain-containing protein 10) (Tristanin)

Protein function

Transcriptional activator, essential for early embryonic development and survival of embryonic stem cells (ESCs) (By similarity). Supports cell growth and survival during early development by transcriptionally activating the expression of the tr

PDB

3IHX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12171	zf-C2H2_jaz	354 → 378	Zinc-finger double-stranded RNA-binding	Family
PF16638	Tristanin_u2	380 → 510		Disordered
PF12874	zf-met	560 → 580		Domain
PF00096	zf-C2H2	644 → 666	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	672 → 695	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	772 → 795	Zinc finger, C2H2 type	Domain

Sequence

MDSKDESSHVWPTSAEHEQNAAQVHFVPDTGTVAQIVYTDDQVRPPQQVVYTADGASYTS
VDGPEHTLVYIHPVEAAQTLFTDPGQVAYVQQDATAQQASLPVHNQVLPSIESVDGSDPL
ATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNN
AHASVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPL
VRGSELKDCYIHLKVSLDKGDRKERDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVA
YQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYEC
NRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSEN
GEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHT
LHLQPQHEESVVPTQSTLTADDMRRAKRIRLELQNAALQHLFIRKSFRPFKCLQCGKAFR
EKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRL
DLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLR
LHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITST
DYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKV
YKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCS
KQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLT
QAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVASATSPHQSQQ
STVDVGQLHDPQPYPQHAIQVQHIQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQ
QQQQQQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTS
GHYVLSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSS
EVHITKP

Sequence length

1147

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Birt-Hogg-Dube syndrome 2	Uncertain significance	rs572787698	RCV005235692
Familial cancer of breast	Benign	rs141414113	RCV005906060

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Birt Hogg Dube Syndrome	Associate	36440963, 37331486, 40028672
Carcinoma	Associate	36734437
Carcinoma Hepatocellular	Associate	29843214
Carcinoma Renal Cell	Associate	36440963, 37331486
Coronary Artery Disease	Associate	22951892
Craniocerebral Trauma	Associate	34969957
Diabetes Mellitus Type 1	Associate	22951892
Dyslexia	Associate	36514817
Esophageal Squamous Cell Carcinoma	Associate	32662828
Extranodal Extension	Associate	36440963
Familial Multiple Lipomatosis	Associate	36440963
Familial multiple trichodiscomas	Associate	37331486
Kidney Neoplasms	Associate	37331486
Lipoma	Associate	37331486
Multiple Myeloma	Associate	35078859
Myelodysplastic Syndromes	Associate	35078859
Nasopharyngeal Carcinoma	Associate	29582644
Neoplasms	Associate	34969957, 36221951, 36734437, 37331486
Papillary renal cell carcinoma sporadic	Associate	37331486
Rhinitis Allergic	Associate	29257233
Sarcoma	Associate	36734437
Soft Tissue Neoplasms	Associate	34969957
Subcutaneous Emphysema	Associate	37331486

PRDM10 (PR/SET domain 10)