Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
56910
Gene name Gene Name - the full gene name approved by the HGNC.
StAR related lipid transfer domain containing 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STARD7
Synonyms (NCBI Gene) Gene synonyms aliases
ADCME, BAFME2, FAME, FAME2, FCMTE2, GTT1
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q11.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016336 hsa-miR-193b-3p Microarray 20304954
MIRT029080 hsa-miR-26b-5p Microarray 19088304
MIRT051638 hsa-let-7e-5p CLASH 23622248
MIRT049177 hsa-miR-92a-3p CLASH 23622248
MIRT047900 hsa-miR-30c-5p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
CTNNB1 Activation 21622533
NR5A1 Activation 21622533
TCF7L2 Activation 21622533
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001773 Process Myeloid dendritic cell activation IEA
GO:0005515 Function Protein binding IPI 27499296, 28514442, 33961781
GO:0005576 Component Extracellular region IEA
GO:0005737 Component Cytoplasm IEA
GO:0005739 Component Mitochondrion HTP 34800366
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616712 18063 ENSG00000084090
Protein
UniProt ID Q9NQZ5
Protein name StAR-related lipid transfer protein 7, mitochondrial (Gestational trophoblastic tumor protein 1) (START domain-containing protein 7) (StARD7)
Protein function May play a protective role in mucosal tissues by preventing exaggerated allergic responses.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01852 START 125 328 START domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in nasal epithelial cells. Down-regulated in nasal epithelial cells in patients experiencing an asthma exacerbation as compared to stable asthmatics and healthy controls. {ECO:0000269|PubMed:25980009}.
Sequence
MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGR
LWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHH
PPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFF
NVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQEN
NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPR
YCVSWMVSSGMPDFLEKLHMATLKAKNM
EIKVKDYISAKPLEMSSEAKATSQSSERKNEG
SCGPARIEYA
Sequence length 370
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Synthesis of PC
<
Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Diabetes Type 2 diabetes (adjusted for BMI) N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Colorectal Neoplasms Stimulate 37191369
Epilepsy Myoclonic Benign Adult Familial Type 2 Associate 31664034