Gene Gene information from NCBI Gene database.
Entrez ID 56893
Gene name Ubiquilin 4
Gene symbol UBQLN4
Synonyms (NCBI Gene)
A1UA1UpC1orf6CIP75UBIN
Chromosome 1
Chromosome location 1q22
miRNA miRNA information provided by mirtarbase database.
612
miRTarBase ID miRNA Experiments Reference
MIRT025950 hsa-miR-7-5p Microarray 17612493
MIRT050691 hsa-miR-18a-5p CLASH 23622248
MIRT044533 hsa-miR-320a CLASH 23622248
MIRT041788 hsa-miR-484 CLASH 23622248
MIRT039209 hsa-miR-769-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
39
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 11001934, 16713569, 18307982, 20940304, 23459205, 27113755, 30612738, 34245648, 35914814
GO:0005634 Component Nucleus IDA 11001934, 29666234, 30612738, 34245648
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005694 Component Chromosome IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605440 1237 ENSG00000160803
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NRR5
Protein name Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Protein function Regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins (PubMed:15280365, PubMed:27113755, PubMed:29666234, PubMed:30612738). Acts by binding polyubiquitin chains of target prot
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin 15 85 Ubiquitin family Domain
PF00627 UBA 558 595 UBA/TS-N domain Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. {ECO:0000269|PubMed:11001934}.
Sequence
MAEPSGAETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQLVLIFAGKI
LKDGDTLNQHGIKDGLTVHLVIKTP
QKAQDPAAATASSPSTPDPASAPSTTPASPATPAQ
PSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFME
LQQQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLN
NPELMRQTMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQ
FGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHP
TVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFA
AQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQ
TEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPATSSPTGASSAQQQLMQQM
IQLLAGSGNSQVQTPEVRFQQQLEQLNSMGFINREANLQALIATGGDINAAIERLLGSQL
S
Sequence length 601
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Protein processing in endoplasmic reticulum
Amyotrophic lateral sclerosis