AZGP1 (alpha-2-glycoprotein 1, zinc-binding)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
563
Gene name Gene Name - the full gene name approved by the HGNC.
Alpha-2-glycoprotein 1, zinc-binding
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
AZGP1
Synonyms (NCBI Gene) Gene synonyms aliases
ZA2G, ZAG
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q22.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(7)
miRTarBase ID miRNA Experiments Reference
MIRT022028 hsa-miR-128-3p Microarray 17612493
MIRT2179179 hsa-miR-188-3p CLIP-seq
MIRT2179180 hsa-miR-3152-5p CLIP-seq
MIRT2179181 hsa-miR-3691-3p CLIP-seq
MIRT2179182 hsa-miR-4317 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(24)
GO ID Ontology Definition Evidence Reference
GO:0001580 Process Detection of chemical stimulus involved in sensory perception of bitter taste IDA 24248522
GO:0001895 Process Retina homeostasis HEP 23580065
GO:0001916 Process Positive regulation of T cell mediated cytotoxicity IBA 21873635
GO:0002476 Process Antigen processing and presentation of endogenous peptide antigen via MHC class Ib IBA 21873635
GO:0002486 Process Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
194460 910 ENSG00000160862
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P25311
Protein name Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)
Protein function Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.
PDB 1T7V , 1T7W , 1T7X , 1T7Y , 1T7Z , 1T80 , 1ZAG , 3ES6 , 6R2U
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00129 MHC_I 26 → 201 Class I Histocompatibility antigen, domains alpha 1 and 2 Domain
PF07654 C1-set 208 → 287 Immunoglobulin C1-set domain Domain
Tissue specificity TISSUE SPECIFICITY: Blood plasma, seminal plasma, urine, saliva, sweat, epithelial cells of various human glands, liver.
Sequence
Sequence length 298
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Miscellaneous transport and binding events
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (4)
Causal
Disease term Disease name dbSNP ID References
Adenocarcinoma Adenocarcinoma, Adenocarcinoma, Basal Cell, Adenocarcinoma, Oxyphilic, Adenocarcinoma, Tubular rs121913530, rs886039394, rs121913474 18978557
Carcinoma Carcinoma, Cribriform, Carcinoma, Granular Cell rs121912654, rs555607708, rs786202962, rs1564055259 18978557
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 18978557
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17173048
Show/Hide Text Mining Associations (82)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Stimulate 17503403
Adenocarcinoma Associate 18978557, 2349965
Adenocarcinoma of Lung Associate 18978557, 32508318
Atherosclerosis Associate 31526290
Autism Spectrum Disorder Inhibit 26290361
Breast Cyst Associate 9114041
Breast Diseases Associate 9114041
Breast Neoplasms Associate 1915885, 22934887, 25561225, 28160560, 34224831, 9114041
Breast Neoplasms Inhibit 40442728
Carcinogenesis Associate 22625427, 23935945