RCC2 (regulator of chromosome condensation 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55920 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Regulator of chromosome condensation 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RCC2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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TD-60 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p36.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomark |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | Q9P258 | |||||||||||||||||||||||||
Protein name | Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa) | |||||||||||||||||||||||||
Protein function | Multifunctional protein that may affect its functions by regulating the activity of small GTPases, such as RAC1 and RALA (PubMed:12919680, PubMed:25074804, PubMed:26158537, PubMed:28869598). Required for normal progress through the cell cycle, b | |||||||||||||||||||||||||
PDB | 5GWN | |||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 522 | |||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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