Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5586
Gene name Gene Name - the full gene name approved by the HGNC.	Protein kinase N2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PKN2
Synonyms (NCBI Gene) Gene synonyms aliases	PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p22.2

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001524	hsa-miR-155-5p	pSILAC	18668040
MIRT001524	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT001524	hsa-miR-155-5p	Proteomics	18668040
MIRT655058	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT655057	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT655056	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT655055	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT655054	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT655053	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT655052	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT655051	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT655050	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT655049	hsa-miR-16-1-3p	HITS-CLIP	23824327
MIRT655048	hsa-miR-1284	HITS-CLIP	23824327
MIRT655047	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT655046	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT655045	hsa-miR-4797-3p	HITS-CLIP	23824327
MIRT655044	hsa-miR-4264	HITS-CLIP	23824327
MIRT149009	hsa-miR-4672	HITS-CLIP	23824327
MIRT655043	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT655042	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT655041	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT080899	hsa-miR-5692a	PAR-CLIP	21572407
MIRT555572	hsa-miR-7109-3p	PAR-CLIP	21572407
MIRT080898	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT080896	hsa-miR-3616-5p	PAR-CLIP	21572407
MIRT080893	hsa-miR-573	PAR-CLIP	21572407
MIRT555571	hsa-let-7c-3p	PAR-CLIP	21572407
MIRT001524	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT001524	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT655058	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT655057	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT655056	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT655055	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT655054	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT655053	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT655052	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT655051	hsa-miR-5582-3p	HITS-CLIP	23824327
MIRT655050	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT655049	hsa-miR-16-1-3p	HITS-CLIP	23824327
MIRT655048	hsa-miR-1284	HITS-CLIP	23824327
MIRT655047	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT655046	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT655045	hsa-miR-4797-3p	HITS-CLIP	23824327
MIRT655044	hsa-miR-4264	HITS-CLIP	23824327
MIRT149009	hsa-miR-4672	HITS-CLIP	23824327
MIRT655043	hsa-miR-4789-5p	HITS-CLIP	23824327
MIRT655042	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT655041	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT080899	hsa-miR-5692a	PAR-CLIP	21572407
MIRT555572	hsa-miR-7109-3p	PAR-CLIP	21572407
MIRT080898	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT080896	hsa-miR-3616-5p	PAR-CLIP	21572407
MIRT080893	hsa-miR-573	PAR-CLIP	21572407
MIRT555571	hsa-let-7c-3p	PAR-CLIP	21572407
MIRT1237744	hsa-let-7a	CLIP-seq
MIRT1237745	hsa-let-7b	CLIP-seq
MIRT1237746	hsa-let-7c	CLIP-seq
MIRT1237747	hsa-let-7d	CLIP-seq
MIRT1237748	hsa-let-7e	CLIP-seq
MIRT1237749	hsa-let-7f	CLIP-seq
MIRT1237750	hsa-let-7g	CLIP-seq
MIRT1237751	hsa-let-7i	CLIP-seq
MIRT1237752	hsa-miR-101	CLIP-seq
MIRT1237753	hsa-miR-105	CLIP-seq
MIRT1237754	hsa-miR-1200	CLIP-seq
MIRT1237755	hsa-miR-1256	CLIP-seq
MIRT1237756	hsa-miR-1287	CLIP-seq
MIRT1237757	hsa-miR-1304	CLIP-seq
MIRT1237758	hsa-miR-144	CLIP-seq
MIRT1237759	hsa-miR-151-3p	CLIP-seq
MIRT1237760	hsa-miR-155	CLIP-seq
MIRT1237761	hsa-miR-183	CLIP-seq
MIRT1237762	hsa-miR-186	CLIP-seq
MIRT1237763	hsa-miR-202	CLIP-seq
MIRT1237764	hsa-miR-204	CLIP-seq
MIRT1237765	hsa-miR-211	CLIP-seq
MIRT1237766	hsa-miR-223	CLIP-seq
MIRT1237767	hsa-miR-27a	CLIP-seq
MIRT1237768	hsa-miR-27b	CLIP-seq
MIRT1237769	hsa-miR-300	CLIP-seq
MIRT1237770	hsa-miR-3122	CLIP-seq
MIRT1237771	hsa-miR-3124-3p	CLIP-seq
MIRT1237772	hsa-miR-3135b	CLIP-seq
MIRT1237773	hsa-miR-3145-3p	CLIP-seq
MIRT1237774	hsa-miR-3162-3p	CLIP-seq
MIRT1237775	hsa-miR-3163	CLIP-seq
MIRT1237776	hsa-miR-3187-3p	CLIP-seq
MIRT1237777	hsa-miR-323-3p	CLIP-seq
MIRT1237778	hsa-miR-338-5p	CLIP-seq
MIRT1237779	hsa-miR-346	CLIP-seq
MIRT1237780	hsa-miR-3609	CLIP-seq
MIRT1237781	hsa-miR-3613-3p	CLIP-seq
MIRT1237782	hsa-miR-3647-5p	CLIP-seq
MIRT1237783	hsa-miR-3662	CLIP-seq
MIRT1237784	hsa-miR-3667-3p	CLIP-seq
MIRT1237785	hsa-miR-381	CLIP-seq
MIRT1237786	hsa-miR-3913-5p	CLIP-seq
MIRT1237787	hsa-miR-3920	CLIP-seq
MIRT1237788	hsa-miR-3945	CLIP-seq
MIRT1237789	hsa-miR-409-5p	CLIP-seq
MIRT1237790	hsa-miR-4252	CLIP-seq
MIRT1237791	hsa-miR-4263	CLIP-seq
MIRT1237792	hsa-miR-4288	CLIP-seq
MIRT1237793	hsa-miR-4305	CLIP-seq
MIRT1237794	hsa-miR-4324	CLIP-seq
MIRT1237795	hsa-miR-4325	CLIP-seq
MIRT1237796	hsa-miR-4326	CLIP-seq
MIRT1237797	hsa-miR-4328	CLIP-seq
MIRT1237798	hsa-miR-4435	CLIP-seq
MIRT1237799	hsa-miR-4436b-5p	CLIP-seq
MIRT1237800	hsa-miR-4458	CLIP-seq
MIRT1237801	hsa-miR-4463	CLIP-seq
MIRT1237802	hsa-miR-4468	CLIP-seq
MIRT1237803	hsa-miR-4470	CLIP-seq
MIRT1237804	hsa-miR-4495	CLIP-seq
MIRT1237805	hsa-miR-4499	CLIP-seq
MIRT1237806	hsa-miR-4500	CLIP-seq
MIRT1237807	hsa-miR-452	CLIP-seq
MIRT1237808	hsa-miR-4639-5p	CLIP-seq
MIRT1237809	hsa-miR-4653-3p	CLIP-seq
MIRT1237810	hsa-miR-4666-3p	CLIP-seq
MIRT1237811	hsa-miR-4666-5p	CLIP-seq
MIRT1237812	hsa-miR-4676-3p	CLIP-seq
MIRT1237813	hsa-miR-4697-3p	CLIP-seq
MIRT1237814	hsa-miR-4700-3p	CLIP-seq
MIRT1237815	hsa-miR-4701-5p	CLIP-seq
MIRT1237816	hsa-miR-4703-3p	CLIP-seq
MIRT1237817	hsa-miR-4720-5p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT1237819	hsa-miR-4755-5p	CLIP-seq
MIRT1237820	hsa-miR-4761-5p	CLIP-seq
MIRT1237821	hsa-miR-4796-3p	CLIP-seq
MIRT1237822	hsa-miR-4799-3p	CLIP-seq
MIRT1237823	hsa-miR-4799-5p	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT1237825	hsa-miR-5095	CLIP-seq
MIRT1237826	hsa-miR-511	CLIP-seq
MIRT1237827	hsa-miR-513a-5p	CLIP-seq
MIRT1237828	hsa-miR-524-3p	CLIP-seq
MIRT1237829	hsa-miR-525-3p	CLIP-seq
MIRT1237830	hsa-miR-544b	CLIP-seq
MIRT1237831	hsa-miR-548aa	CLIP-seq
MIRT1237832	hsa-miR-548ah	CLIP-seq
MIRT1237833	hsa-miR-548s	CLIP-seq
MIRT1237834	hsa-miR-548t	CLIP-seq
MIRT1237835	hsa-miR-552	CLIP-seq
MIRT1237836	hsa-miR-576-5p	CLIP-seq
MIRT1237837	hsa-miR-582-3p	CLIP-seq
MIRT1237838	hsa-miR-582-5p	CLIP-seq
MIRT1237839	hsa-miR-584	CLIP-seq
MIRT1237840	hsa-miR-588	CLIP-seq
MIRT1237841	hsa-miR-600	CLIP-seq
MIRT1237842	hsa-miR-623	CLIP-seq
MIRT1237843	hsa-miR-626	CLIP-seq
MIRT1237844	hsa-miR-632	CLIP-seq
MIRT1237845	hsa-miR-659	CLIP-seq
MIRT1237846	hsa-miR-892a	CLIP-seq
MIRT1237847	hsa-miR-98	CLIP-seq
MIRT1552325	hsa-miR-1208	CLIP-seq
MIRT1552326	hsa-miR-143	CLIP-seq
MIRT1552327	hsa-miR-3121-3p	CLIP-seq
MIRT1552328	hsa-miR-3658	CLIP-seq
MIRT1552329	hsa-miR-3670	CLIP-seq
MIRT1552330	hsa-miR-4770	CLIP-seq
MIRT1552331	hsa-miR-556-5p	CLIP-seq
MIRT1237744	hsa-let-7a	CLIP-seq
MIRT1237745	hsa-let-7b	CLIP-seq
MIRT1237746	hsa-let-7c	CLIP-seq
MIRT1237747	hsa-let-7d	CLIP-seq
MIRT1237748	hsa-let-7e	CLIP-seq
MIRT1237749	hsa-let-7f	CLIP-seq
MIRT1237750	hsa-let-7g	CLIP-seq
MIRT1237751	hsa-let-7i	CLIP-seq
MIRT1237752	hsa-miR-101	CLIP-seq
MIRT1237753	hsa-miR-105	CLIP-seq
MIRT1237754	hsa-miR-1200	CLIP-seq
MIRT2069893	hsa-miR-124	CLIP-seq
MIRT2069894	hsa-miR-1279	CLIP-seq
MIRT1237757	hsa-miR-1304	CLIP-seq
MIRT2069895	hsa-miR-137	CLIP-seq
MIRT1237758	hsa-miR-144	CLIP-seq
MIRT2069896	hsa-miR-1825	CLIP-seq
MIRT1237761	hsa-miR-183	CLIP-seq
MIRT2069897	hsa-miR-199a-5p	CLIP-seq
MIRT2069898	hsa-miR-199b-5p	CLIP-seq
MIRT1237763	hsa-miR-202	CLIP-seq
MIRT2069899	hsa-miR-296-3p	CLIP-seq
MIRT1552327	hsa-miR-3121-3p	CLIP-seq
MIRT1237771	hsa-miR-3124-3p	CLIP-seq
MIRT1237772	hsa-miR-3135b	CLIP-seq
MIRT2069900	hsa-miR-3140-3p	CLIP-seq
MIRT2069901	hsa-miR-3150b-3p	CLIP-seq
MIRT2069902	hsa-miR-3157-3p	CLIP-seq
MIRT2069903	hsa-miR-3160-5p	CLIP-seq
MIRT1237775	hsa-miR-3163	CLIP-seq
MIRT2069904	hsa-miR-3179	CLIP-seq
MIRT1237778	hsa-miR-338-5p	CLIP-seq
MIRT1237779	hsa-miR-346	CLIP-seq
MIRT2069905	hsa-miR-3591-5p	CLIP-seq
MIRT2069906	hsa-miR-3606	CLIP-seq
MIRT1237781	hsa-miR-3613-3p	CLIP-seq
MIRT2069907	hsa-miR-3613-5p	CLIP-seq
MIRT2069908	hsa-miR-3646	CLIP-seq
MIRT1552328	hsa-miR-3658	CLIP-seq
MIRT1237784	hsa-miR-3667-3p	CLIP-seq
MIRT1237788	hsa-miR-3945	CLIP-seq
MIRT2069909	hsa-miR-409-3p	CLIP-seq
MIRT1237789	hsa-miR-409-5p	CLIP-seq
MIRT2069910	hsa-miR-4255	CLIP-seq
MIRT1237792	hsa-miR-4288	CLIP-seq
MIRT2069911	hsa-miR-4290	CLIP-seq
MIRT2069912	hsa-miR-4297	CLIP-seq
MIRT1237794	hsa-miR-4324	CLIP-seq
MIRT1237795	hsa-miR-4325	CLIP-seq
MIRT1237799	hsa-miR-4436b-5p	CLIP-seq
MIRT2069913	hsa-miR-4453	CLIP-seq
MIRT1237800	hsa-miR-4458	CLIP-seq
MIRT1237803	hsa-miR-4470	CLIP-seq
MIRT2069914	hsa-miR-4473	CLIP-seq
MIRT1237804	hsa-miR-4495	CLIP-seq
MIRT1237806	hsa-miR-4500	CLIP-seq
MIRT2069915	hsa-miR-4538	CLIP-seq
MIRT1237809	hsa-miR-4653-3p	CLIP-seq
MIRT2069916	hsa-miR-4659a-3p	CLIP-seq
MIRT2069917	hsa-miR-4659b-3p	CLIP-seq
MIRT2069918	hsa-miR-4671-3p	CLIP-seq
MIRT2069919	hsa-miR-4689	CLIP-seq
MIRT2069920	hsa-miR-4699-3p	CLIP-seq
MIRT2069921	hsa-miR-4709-3p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT2069922	hsa-miR-4735-5p	CLIP-seq
MIRT2069923	hsa-miR-4760-3p	CLIP-seq
MIRT2069924	hsa-miR-4775	CLIP-seq
MIRT2069925	hsa-miR-4778-3p	CLIP-seq
MIRT2069926	hsa-miR-4784	CLIP-seq
MIRT2069927	hsa-miR-488	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT2069928	hsa-miR-506	CLIP-seq
MIRT2069929	hsa-miR-512-3p	CLIP-seq
MIRT2069930	hsa-miR-520f	CLIP-seq
MIRT1237828	hsa-miR-524-3p	CLIP-seq
MIRT1237829	hsa-miR-525-3p	CLIP-seq
MIRT1237830	hsa-miR-544b	CLIP-seq
MIRT2069931	hsa-miR-548ae	CLIP-seq
MIRT2069932	hsa-miR-548aj	CLIP-seq
MIRT2069933	hsa-miR-548am	CLIP-seq
MIRT2069934	hsa-miR-548an	CLIP-seq
MIRT2069935	hsa-miR-548x	CLIP-seq
MIRT1237836	hsa-miR-576-5p	CLIP-seq
MIRT2069936	hsa-miR-578	CLIP-seq
MIRT2069937	hsa-miR-579	CLIP-seq
MIRT2069938	hsa-miR-580	CLIP-seq
MIRT2069939	hsa-miR-581	CLIP-seq
MIRT1237839	hsa-miR-584	CLIP-seq
MIRT2069940	hsa-miR-590-3p	CLIP-seq
MIRT1237844	hsa-miR-632	CLIP-seq
MIRT2069941	hsa-miR-636	CLIP-seq
MIRT2069942	hsa-miR-874	CLIP-seq
MIRT1237847	hsa-miR-98	CLIP-seq
MIRT1237744	hsa-let-7a	CLIP-seq
MIRT1237745	hsa-let-7b	CLIP-seq
MIRT1237746	hsa-let-7c	CLIP-seq
MIRT1237747	hsa-let-7d	CLIP-seq
MIRT1237748	hsa-let-7e	CLIP-seq
MIRT1237749	hsa-let-7f	CLIP-seq
MIRT1237750	hsa-let-7g	CLIP-seq
MIRT1237751	hsa-let-7i	CLIP-seq
MIRT1237754	hsa-miR-1200	CLIP-seq
MIRT1237757	hsa-miR-1304	CLIP-seq
MIRT2297240	hsa-miR-139-5p	CLIP-seq
MIRT2297241	hsa-miR-146a	CLIP-seq
MIRT2297242	hsa-miR-146b-5p	CLIP-seq
MIRT1237760	hsa-miR-155	CLIP-seq
MIRT2069896	hsa-miR-1825	CLIP-seq
MIRT2069897	hsa-miR-199a-5p	CLIP-seq
MIRT2069898	hsa-miR-199b-5p	CLIP-seq
MIRT1237763	hsa-miR-202	CLIP-seq
MIRT1237766	hsa-miR-223	CLIP-seq
MIRT1237769	hsa-miR-300	CLIP-seq
MIRT2297243	hsa-miR-3120-3p	CLIP-seq
MIRT1552327	hsa-miR-3121-3p	CLIP-seq
MIRT2297244	hsa-miR-3166	CLIP-seq
MIRT1237776	hsa-miR-3187-3p	CLIP-seq
MIRT2069905	hsa-miR-3591-5p	CLIP-seq
MIRT1237780	hsa-miR-3609	CLIP-seq
MIRT1237781	hsa-miR-3613-3p	CLIP-seq
MIRT1237782	hsa-miR-3647-5p	CLIP-seq
MIRT1552328	hsa-miR-3658	CLIP-seq
MIRT2297245	hsa-miR-3672	CLIP-seq
MIRT2297246	hsa-miR-374a	CLIP-seq
MIRT2297247	hsa-miR-374b	CLIP-seq
MIRT1237785	hsa-miR-381	CLIP-seq
MIRT1237789	hsa-miR-409-5p	CLIP-seq
MIRT1237790	hsa-miR-4252	CLIP-seq
MIRT2069910	hsa-miR-4255	CLIP-seq
MIRT1237794	hsa-miR-4324	CLIP-seq
MIRT1237797	hsa-miR-4328	CLIP-seq
MIRT1237798	hsa-miR-4435	CLIP-seq
MIRT1237800	hsa-miR-4458	CLIP-seq
MIRT1237802	hsa-miR-4468	CLIP-seq
MIRT2297248	hsa-miR-4494	CLIP-seq
MIRT1237806	hsa-miR-4500	CLIP-seq
MIRT1237808	hsa-miR-4639-5p	CLIP-seq
MIRT1237810	hsa-miR-4666-3p	CLIP-seq
MIRT1237813	hsa-miR-4697-3p	CLIP-seq
MIRT1237815	hsa-miR-4701-5p	CLIP-seq
MIRT1237816	hsa-miR-4703-3p	CLIP-seq
MIRT2069921	hsa-miR-4709-3p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT2069923	hsa-miR-4760-3p	CLIP-seq
MIRT2297249	hsa-miR-4771	CLIP-seq
MIRT2297250	hsa-miR-4777-3p	CLIP-seq
MIRT2069925	hsa-miR-4778-3p	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT1237830	hsa-miR-544b	CLIP-seq
MIRT1237831	hsa-miR-548aa	CLIP-seq
MIRT1237832	hsa-miR-548ah	CLIP-seq
MIRT2297251	hsa-miR-548n	CLIP-seq
MIRT1237833	hsa-miR-548s	CLIP-seq
MIRT1237834	hsa-miR-548t	CLIP-seq
MIRT2069936	hsa-miR-578	CLIP-seq
MIRT2069937	hsa-miR-579	CLIP-seq
MIRT2069938	hsa-miR-580	CLIP-seq
MIRT2069939	hsa-miR-581	CLIP-seq
MIRT1237839	hsa-miR-584	CLIP-seq
MIRT1237840	hsa-miR-588	CLIP-seq
MIRT2297252	hsa-miR-589	CLIP-seq
MIRT1237843	hsa-miR-626	CLIP-seq
MIRT2297253	hsa-miR-664	CLIP-seq
MIRT1237846	hsa-miR-892a	CLIP-seq
MIRT2297254	hsa-miR-922	CLIP-seq
MIRT1237847	hsa-miR-98	CLIP-seq
MIRT2392584	hsa-miR-340	CLIP-seq
MIRT2069905	hsa-miR-3591-5p	CLIP-seq
MIRT2069906	hsa-miR-3606	CLIP-seq
MIRT2069912	hsa-miR-4297	CLIP-seq
MIRT1237808	hsa-miR-4639-5p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT2069922	hsa-miR-4735-5p	CLIP-seq
MIRT2069924	hsa-miR-4775	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT1237836	hsa-miR-576-5p	CLIP-seq
MIRT2069940	hsa-miR-590-3p	CLIP-seq
MIRT2432143	hsa-miR-921	CLIP-seq
MIRT2442464	hsa-miR-153	CLIP-seq
MIRT2442465	hsa-miR-4280	CLIP-seq
MIRT2069937	hsa-miR-579	CLIP-seq
MIRT2465846	hsa-miR-326	CLIP-seq
MIRT2465847	hsa-miR-330-5p	CLIP-seq
MIRT2069908	hsa-miR-3646	CLIP-seq
MIRT2465848	hsa-miR-378	CLIP-seq
MIRT2465849	hsa-miR-378b	CLIP-seq
MIRT2465850	hsa-miR-378c	CLIP-seq
MIRT2465851	hsa-miR-378d	CLIP-seq
MIRT2465852	hsa-miR-378e	CLIP-seq
MIRT2465853	hsa-miR-378f	CLIP-seq
MIRT2465854	hsa-miR-378h	CLIP-seq
MIRT2465855	hsa-miR-378i	CLIP-seq
MIRT2465856	hsa-miR-422a	CLIP-seq
MIRT2465857	hsa-miR-4638-3p	CLIP-seq
MIRT2465858	hsa-miR-4695-3p	CLIP-seq
MIRT1237744	hsa-let-7a	CLIP-seq
MIRT1237745	hsa-let-7b	CLIP-seq
MIRT1237746	hsa-let-7c	CLIP-seq
MIRT1237747	hsa-let-7d	CLIP-seq
MIRT1237748	hsa-let-7e	CLIP-seq
MIRT1237749	hsa-let-7f	CLIP-seq
MIRT1237750	hsa-let-7g	CLIP-seq
MIRT1237751	hsa-let-7i	CLIP-seq
MIRT1237752	hsa-miR-101	CLIP-seq
MIRT1237754	hsa-miR-1200	CLIP-seq
MIRT1552325	hsa-miR-1208	CLIP-seq
MIRT2069894	hsa-miR-1279	CLIP-seq
MIRT1237757	hsa-miR-1304	CLIP-seq
MIRT2594563	hsa-miR-142-5p	CLIP-seq
MIRT1552326	hsa-miR-143	CLIP-seq
MIRT1237758	hsa-miR-144	CLIP-seq
MIRT2594564	hsa-miR-145	CLIP-seq
MIRT2442464	hsa-miR-153	CLIP-seq
MIRT1237760	hsa-miR-155	CLIP-seq
MIRT2069896	hsa-miR-1825	CLIP-seq
MIRT2069897	hsa-miR-199a-5p	CLIP-seq
MIRT2069898	hsa-miR-199b-5p	CLIP-seq
MIRT1237763	hsa-miR-202	CLIP-seq
MIRT1237766	hsa-miR-223	CLIP-seq
MIRT2069899	hsa-miR-296-3p	CLIP-seq
MIRT2594565	hsa-miR-3065-5p	CLIP-seq
MIRT1552327	hsa-miR-3121-3p	CLIP-seq
MIRT1237773	hsa-miR-3145-3p	CLIP-seq
MIRT2069901	hsa-miR-3150b-3p	CLIP-seq
MIRT1237775	hsa-miR-3163	CLIP-seq
MIRT2069904	hsa-miR-3179	CLIP-seq
MIRT2594566	hsa-miR-3180-5p	CLIP-seq
MIRT2594567	hsa-miR-3185	CLIP-seq
MIRT2594568	hsa-miR-320a	CLIP-seq
MIRT2594569	hsa-miR-320b	CLIP-seq
MIRT2594570	hsa-miR-320c	CLIP-seq
MIRT2594571	hsa-miR-320d	CLIP-seq
MIRT2392584	hsa-miR-340	CLIP-seq
MIRT2069905	hsa-miR-3591-5p	CLIP-seq
MIRT1237781	hsa-miR-3613-3p	CLIP-seq
MIRT2594572	hsa-miR-3622a-3p	CLIP-seq
MIRT2594573	hsa-miR-3622b-3p	CLIP-seq
MIRT2069908	hsa-miR-3646	CLIP-seq
MIRT1552328	hsa-miR-3658	CLIP-seq
MIRT1552329	hsa-miR-3670	CLIP-seq
MIRT2594574	hsa-miR-3676	CLIP-seq
MIRT2594575	hsa-miR-3686	CLIP-seq
MIRT2594576	hsa-miR-376a	CLIP-seq
MIRT2594577	hsa-miR-376b	CLIP-seq
MIRT1237789	hsa-miR-409-5p	CLIP-seq
MIRT2594578	hsa-miR-412	CLIP-seq
MIRT2069910	hsa-miR-4255	CLIP-seq
MIRT2594579	hsa-miR-4266	CLIP-seq
MIRT2594580	hsa-miR-4275	CLIP-seq
MIRT2442465	hsa-miR-4280	CLIP-seq
MIRT2594581	hsa-miR-4282	CLIP-seq
MIRT1237794	hsa-miR-4324	CLIP-seq
MIRT1237797	hsa-miR-4328	CLIP-seq
MIRT2594582	hsa-miR-4429	CLIP-seq
MIRT1237800	hsa-miR-4458	CLIP-seq
MIRT1237806	hsa-miR-4500	CLIP-seq
MIRT1237807	hsa-miR-452	CLIP-seq
MIRT1237808	hsa-miR-4639-5p	CLIP-seq
MIRT2594583	hsa-miR-4643	CLIP-seq
MIRT2594584	hsa-miR-466	CLIP-seq
MIRT2594585	hsa-miR-4668-3p	CLIP-seq
MIRT1237812	hsa-miR-4676-3p	CLIP-seq
MIRT2069919	hsa-miR-4689	CLIP-seq
MIRT1237813	hsa-miR-4697-3p	CLIP-seq
MIRT2069920	hsa-miR-4699-3p	CLIP-seq
MIRT1237816	hsa-miR-4703-3p	CLIP-seq
MIRT2069921	hsa-miR-4709-3p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT2069922	hsa-miR-4735-5p	CLIP-seq
MIRT2594586	hsa-miR-4738-3p	CLIP-seq
MIRT2069923	hsa-miR-4760-3p	CLIP-seq
MIRT2594587	hsa-miR-4762-5p	CLIP-seq
MIRT1552330	hsa-miR-4770	CLIP-seq
MIRT2069925	hsa-miR-4778-3p	CLIP-seq
MIRT2594588	hsa-miR-4778-5p	CLIP-seq
MIRT2069926	hsa-miR-4784	CLIP-seq
MIRT2594589	hsa-miR-4789-3p	CLIP-seq
MIRT2594590	hsa-miR-4790-3p	CLIP-seq
MIRT1237823	hsa-miR-4799-5p	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT1237826	hsa-miR-511	CLIP-seq
MIRT1237830	hsa-miR-544b	CLIP-seq
MIRT2594591	hsa-miR-548ac	CLIP-seq
MIRT2069931	hsa-miR-548ae	CLIP-seq
MIRT2069932	hsa-miR-548aj	CLIP-seq
MIRT2069933	hsa-miR-548am	CLIP-seq
MIRT2594592	hsa-miR-548d-3p	CLIP-seq
MIRT2594593	hsa-miR-548g	CLIP-seq
MIRT2594594	hsa-miR-548p	CLIP-seq
MIRT2069935	hsa-miR-548x	CLIP-seq
MIRT2594595	hsa-miR-548z	CLIP-seq
MIRT1552331	hsa-miR-556-5p	CLIP-seq
MIRT2069936	hsa-miR-578	CLIP-seq
MIRT2069937	hsa-miR-579	CLIP-seq
MIRT2069939	hsa-miR-581	CLIP-seq
MIRT1237838	hsa-miR-582-5p	CLIP-seq
MIRT1237839	hsa-miR-584	CLIP-seq
MIRT2069940	hsa-miR-590-3p	CLIP-seq
MIRT2594596	hsa-miR-617	CLIP-seq
MIRT1237843	hsa-miR-626	CLIP-seq
MIRT1237846	hsa-miR-892a	CLIP-seq
MIRT1237847	hsa-miR-98	CLIP-seq
MIRT1237744	hsa-let-7a	CLIP-seq
MIRT1237745	hsa-let-7b	CLIP-seq
MIRT1237746	hsa-let-7c	CLIP-seq
MIRT1237747	hsa-let-7d	CLIP-seq
MIRT1237748	hsa-let-7e	CLIP-seq
MIRT1237749	hsa-let-7f	CLIP-seq
MIRT1237750	hsa-let-7g	CLIP-seq
MIRT1237751	hsa-let-7i	CLIP-seq
MIRT1237752	hsa-miR-101	CLIP-seq
MIRT1237754	hsa-miR-1200	CLIP-seq
MIRT1552325	hsa-miR-1208	CLIP-seq
MIRT2069894	hsa-miR-1279	CLIP-seq
MIRT2594563	hsa-miR-142-5p	CLIP-seq
MIRT1552326	hsa-miR-143	CLIP-seq
MIRT1237758	hsa-miR-144	CLIP-seq
MIRT2594564	hsa-miR-145	CLIP-seq
MIRT2442464	hsa-miR-153	CLIP-seq
MIRT2069896	hsa-miR-1825	CLIP-seq
MIRT2069897	hsa-miR-199a-5p	CLIP-seq
MIRT2069898	hsa-miR-199b-5p	CLIP-seq
MIRT1237763	hsa-miR-202	CLIP-seq
MIRT2069899	hsa-miR-296-3p	CLIP-seq
MIRT1552327	hsa-miR-3121-3p	CLIP-seq
MIRT1237773	hsa-miR-3145-3p	CLIP-seq
MIRT2069901	hsa-miR-3150b-3p	CLIP-seq
MIRT1237775	hsa-miR-3163	CLIP-seq
MIRT2069904	hsa-miR-3179	CLIP-seq
MIRT2594566	hsa-miR-3180-5p	CLIP-seq
MIRT2594567	hsa-miR-3185	CLIP-seq
MIRT2594572	hsa-miR-3622a-3p	CLIP-seq
MIRT2594573	hsa-miR-3622b-3p	CLIP-seq
MIRT2069908	hsa-miR-3646	CLIP-seq
MIRT1552328	hsa-miR-3658	CLIP-seq
MIRT1552329	hsa-miR-3670	CLIP-seq
MIRT2594574	hsa-miR-3676	CLIP-seq
MIRT2594575	hsa-miR-3686	CLIP-seq
MIRT2594576	hsa-miR-376a	CLIP-seq
MIRT2594577	hsa-miR-376b	CLIP-seq
MIRT1237789	hsa-miR-409-5p	CLIP-seq
MIRT2594578	hsa-miR-412	CLIP-seq
MIRT2594579	hsa-miR-4266	CLIP-seq
MIRT2594580	hsa-miR-4275	CLIP-seq
MIRT2442465	hsa-miR-4280	CLIP-seq
MIRT1237794	hsa-miR-4324	CLIP-seq
MIRT1237800	hsa-miR-4458	CLIP-seq
MIRT1237806	hsa-miR-4500	CLIP-seq
MIRT1237807	hsa-miR-452	CLIP-seq
MIRT1237808	hsa-miR-4639-5p	CLIP-seq
MIRT2594583	hsa-miR-4643	CLIP-seq
MIRT2594584	hsa-miR-466	CLIP-seq
MIRT2594585	hsa-miR-4668-3p	CLIP-seq
MIRT1237812	hsa-miR-4676-3p	CLIP-seq
MIRT2069919	hsa-miR-4689	CLIP-seq
MIRT2069920	hsa-miR-4699-3p	CLIP-seq
MIRT2069921	hsa-miR-4709-3p	CLIP-seq
MIRT1237818	hsa-miR-4725-5p	CLIP-seq
MIRT2069922	hsa-miR-4735-5p	CLIP-seq
MIRT2594586	hsa-miR-4738-3p	CLIP-seq
MIRT2069923	hsa-miR-4760-3p	CLIP-seq
MIRT2594587	hsa-miR-4762-5p	CLIP-seq
MIRT1552330	hsa-miR-4770	CLIP-seq
MIRT2069925	hsa-miR-4778-3p	CLIP-seq
MIRT2594588	hsa-miR-4778-5p	CLIP-seq
MIRT2069926	hsa-miR-4784	CLIP-seq
MIRT2594589	hsa-miR-4789-3p	CLIP-seq
MIRT2594590	hsa-miR-4790-3p	CLIP-seq
MIRT1237823	hsa-miR-4799-5p	CLIP-seq
MIRT1237824	hsa-miR-504	CLIP-seq
MIRT1237826	hsa-miR-511	CLIP-seq
MIRT1237830	hsa-miR-544b	CLIP-seq
MIRT2594591	hsa-miR-548ac	CLIP-seq
MIRT2069931	hsa-miR-548ae	CLIP-seq
MIRT2069932	hsa-miR-548aj	CLIP-seq
MIRT2069933	hsa-miR-548am	CLIP-seq
MIRT2594592	hsa-miR-548d-3p	CLIP-seq
MIRT2594593	hsa-miR-548g	CLIP-seq
MIRT2594594	hsa-miR-548p	CLIP-seq
MIRT2069935	hsa-miR-548x	CLIP-seq
MIRT2594595	hsa-miR-548z	CLIP-seq
MIRT1552331	hsa-miR-556-5p	CLIP-seq
MIRT2069936	hsa-miR-578	CLIP-seq
MIRT2069937	hsa-miR-579	CLIP-seq
MIRT2069939	hsa-miR-581	CLIP-seq
MIRT1237838	hsa-miR-582-5p	CLIP-seq
MIRT1237839	hsa-miR-584	CLIP-seq
MIRT2594596	hsa-miR-617	CLIP-seq
MIRT1237847	hsa-miR-98	CLIP-seq

Show/Hide all(63)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	7851406
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	20188095
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004697	Function	Diacylglycerol-dependent serine/threonine kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	TAS
GO:0005515	Function	Protein binding	IPI	10026169, 11356191, 15364941, 17110931, 20974804, 26638075, 27104747, 35271311
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	11356191
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	17332740
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0006468	Process	Protein phosphorylation	IDA	17332740
GO:0006468	Process	Protein phosphorylation	TAS	9092545
GO:0006915	Process	Apoptotic process	IEA
GO:0007155	Process	Cell adhesion	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	7851406
GO:0010631	Process	Epithelial cell migration	IDA	21754995
GO:0010631	Process	Epithelial cell migration	IEA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IDA	15364941
GO:0016301	Function	Kinase activity	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0030027	Component	Lamellipodium	IDA	11356191
GO:0030027	Component	Lamellipodium	IEA
GO:0030030	Process	Cell projection organization	IEA
GO:0030496	Component	Midbody	IDA	17332740
GO:0030496	Component	Midbody	IEA
GO:0031267	Function	Small GTPase binding	IEA
GO:0032154	Component	Cleavage furrow	IDA	17332740
GO:0032154	Component	Cleavage furrow	IEA
GO:0032467	Process	Positive regulation of cytokinesis	IMP	17332740
GO:0032991	Component	Protein-containing complex	IDA	23223530
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0042826	Function	Histone deacetylase binding	IDA	20188095
GO:0042995	Component	Cell projection	IEA
GO:0043296	Component	Apical junction complex	IDA	20974804
GO:0043296	Component	Apical junction complex	IEA
GO:0043297	Process	Apical junction assembly	IEA
GO:0043297	Process	Apical junction assembly	IMP	20974804
GO:0045070	Process	Positive regulation of viral genome replication	IMP	15364941
GO:0045111	Component	Intermediate filament cytoskeleton	IDA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045931	Process	Positive regulation of mitotic cell cycle	IMP	17332740
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	15364941
GO:0051301	Process	Cell division	IEA
GO:0070063	Function	RNA polymerase binding	IPI	15364941
GO:0070161	Component	Anchoring junction	IEA
GO:0097700	Process	Vascular endothelial cell response to laminar fluid shear stress	TAS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0106310	Function	Protein serine kinase activity	TAS
GO:2000145	Process	Regulation of cell motility	IMP	21754995

MIM	HGNC	e!Ensembl
602549	9406	ENSG00000065243

Protein

UniProt ID

Q16513

Protein name

Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)

Protein function

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migrati

PDB

4CRS , 4RRV , 6CCY , 6GBE

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02185	HR1	49 → 111	Hr1 repeat	Family
PF02185	HR1	137 → 204	Hr1 repeat	Family
PF02185	HR1	218 → 285	Hr1 repeat	Family
PF00069	Pkinase	657 → 916	Protein kinase domain	Domain
PF00433	Pkinase_C	937 → 979	Protein kinase C terminal domain	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells. {ECO:0000269|PubMed:10026169, ECO:0000269|PubMed:21754995}.

Sequence

MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL
KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR
TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL
QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM
KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA
ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS
PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK
FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN
PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV
PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG
QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC
AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL
VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY
RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW
WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL
GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP
REPRILSEEEQEMFRDFDYIADWC

Sequence length

984

Interactions

View interactions

	KEGG		Reactome
	PI3K-Akt signaling pathway NOD-like receptor signaling pathway Yersinia infection		RHO GTPases activate PKNs

Show/Hide Unknown Diseases (10)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Dementia	Dementia	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Glaucoma	Glaucoma	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Irritable Bowel Syndrome	Irritable bowel syndrome	N/A	N/A	GWAS
Narcolepsy	Narcolepsy	N/A	N/A	GWAS
Prostate cancer	Prostate cancer	N/A	N/A	GWAS

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	26296974
Asthma	Associate	30737985
Atrial Fibrillation	Associate	23593175
Breast Neoplasms	Associate	31759986
Colorectal Neoplasms	Associate	29368606, 33658394
Diabetes Mellitus Type 2	Associate	21084393, 38034011
Myopathies Structural Congenital	Associate	29368606
Neoplasm Metastasis	Associate	34455760
Neoplasms	Associate	26296974, 34455760
Neoplasms	Inhibit	29368606, 31759986
Neuroendocrine Tumors	Associate	34571875
Neurofibromatosis 2	Associate	34571875
Prostatic Neoplasms	Associate	26296974
Stomach Neoplasms	Associate	33879018
Toe Syndactyly Telecanthus and Anogenital and Renal Malformations	Associate	27104747

PKN2 (protein kinase N2)