PKN2 (protein kinase N2)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 5586 |
| Gene name | Protein kinase N2 |
| Gene symbol | PKN2 |
| Synonyms (NCBI Gene) |
PAK2PRK2PRKCL2PRO2042Pak-2STK7
|
| Chromosome | 1 |
| Chromosome location | 1p22.2 |
|
miRNA
miRNA information provided by mirtarbase database.
556
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
63
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||||||||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q16513 | ||||||||||||||||||||||||||||||
| Protein name | Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) | ||||||||||||||||||||||||||||||
| Protein function | PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migrati | ||||||||||||||||||||||||||||||
| PDB | 4CRS , 4RRV , 6CCY , 6GBE | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells. {ECO:0000269|PubMed:10026169, ECO:0000269|PubMed:21754995}. | ||||||||||||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||||||||||||
| Sequence length | 984 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
|||||||||
|
Associated diseases
Disease associations from ClinVar (Causal/Unknown) and external databases: GenCC, Orphanet, ClinGen, HPO, DisGeNET, CTD, GWAS Catalog.
23
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||