CNDP2 (carnosine dipeptidase 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55748 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Carnosine dipeptidase 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CNDP2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CN2, CPGL, HEL-S-13, HsT2298, PEPA |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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CN2 |
Chromosome
Chromosome number
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18 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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18q22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q96KP4 | |||||||||||||||
Protein name | Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A) (Threonyl dipeptidase) | |||||||||||||||
Protein function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue-specific way (By similarity). Has high dipeptidase activity t | |||||||||||||||
PDB | 4RUH | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: [Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues | |||||||||||||||
Sequence | ||||||||||||||||
Sequence length | 475 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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