SLC30A6 (solute carrier family 30 member 6)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55676 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 30 member 6 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC30A6 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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MST103, MSTP103, ZNT6 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer`s disease brain plaques. [provided b |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q6NXT4 | ||||||||||
Protein name | Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6) | ||||||||||
Protein function | Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (PubMed:15994300, PubMed:19366695, | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kid | ||||||||||
Sequence |
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Sequence length | 461 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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