NPLOC4 (NPL4 homolog, ubiquitin recognition factor)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55666 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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NPL4 homolog, ubiquitin recognition factor |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NPLOC4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NPL4 |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q25.3 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q8TAT6 | ||||||||||||||||||||
Protein name | Nuclear protein localization protein 4 homolog (Protein NPL4) | ||||||||||||||||||||
Protein function | The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates | ||||||||||||||||||||
PDB | 7WWP , 7WWQ | ||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver. {ECO:0000269|PubMed:11574150}. | ||||||||||||||||||||
Sequence | |||||||||||||||||||||
Sequence length | 608 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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