Gene Gene information from NCBI Gene database.
Entrez ID 55664
Gene name Cell division cycle 37 like 1, HSP90 cochaperone
Gene symbol CDC37L1
Synonyms (NCBI Gene)
CDC37BHARC
Chromosome 9
Chromosome location 9p24.1
Summary CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
555
miRTarBase ID miRNA Experiments Reference
MIRT020478 hsa-miR-106b-5p Microarray 17242205
MIRT027214 hsa-miR-103a-3p Sequencing 20371350
MIRT028177 hsa-miR-93-5p Sequencing 20371350
MIRT032005 hsa-miR-16-5p Sequencing 20371350
MIRT042137 hsa-miR-484 CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21988832, 25036637, 25416956, 32814053, 33961781
GO:0005576 Component Extracellular region TAS
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610346 17179 ENSG00000106993
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7L3B6
Protein name Hsp90 co-chaperone Cdc37-like 1 (Hsp90-associating relative of Cdc37)
Protein function Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08565 CDC37_M 168 278 Cdc37 Hsp90 binding domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in brain, heart, kidney, liver, placenta and skeletal muscle. {ECO:0000269|PubMed:11413142}.
Sequence
MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEF
VKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQR
EKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQR
FLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGC
FRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQS
FQPMTVQNHVPHSGVGSIGLLE
SLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV
Sequence length 337
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Platelet degranulation