NAGK (N-acetylglucosamine kinase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55577 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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N-acetylglucosamine kinase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NAGK |
Synonyms (NCBI Gene)
Gene synonyms aliases
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GNK, HSA242910 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p13.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by R |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9UJ70 | ||||||||||
Protein name | N-acetyl-D-glucosamine kinase (N-acetylglucosamine kinase) (EC 2.7.1.59) (GlcNAc kinase) (Muramyl dipeptide kinase) (EC 2.7.1.-) (N-acetyl-D-mannosamine kinase) (EC 2.7.1.60) | ||||||||||
Protein function | Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate (PubMed:22692205). Involved in the N-glycolylneuraminic acid (Neu5Gc) degrada | ||||||||||
PDB | 2CH5 , 2CH6 | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10824116}. | ||||||||||
Sequence | |||||||||||
Sequence length | 344 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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