Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55359
Gene name Gene Name - the full gene name approved by the HGNC.
Serine/threonine/tyrosine kinase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STYK1
Synonyms (NCBI Gene) Gene synonyms aliases
NOK, SuRTK106
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.2
Summary Summary of gene provided in NCBI Entrez Gene.
Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT712045 hsa-miR-2116-5p HITS-CLIP 19536157
MIRT712044 hsa-miR-22-5p HITS-CLIP 19536157
MIRT712043 hsa-miR-4666a-5p HITS-CLIP 19536157
MIRT712042 hsa-miR-4677-5p HITS-CLIP 19536157
MIRT270128 hsa-miR-653-5p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0004672 Function Protein kinase activity IEA
GO:0004713 Function Protein tyrosine kinase activity IEA
GO:0004715 Function Non-membrane spanning protein tyrosine kinase activity IBA
GO:0004715 Function Non-membrane spanning protein tyrosine kinase activity IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611433 18889 ENSG00000060140
Protein
UniProt ID Q6J9G0
Protein name Tyrosine-protein kinase STYK1 (EC 2.7.10.2) (Novel oncogene with kinase domain) (Protein PK-unique) (Serine/threonine/tyrosine kinase 1)
Protein function Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase an
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07714 PK_Tyr_Ser-Thr 114 380 Protein tyrosine and serine/threonine kinase Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells L-02, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K-562, but not in o
Sequence
Sequence length 422
Interactions View interactions
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