PI4K2B (phosphatidylinositol 4-kinase type 2 beta)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 55300 |
| Gene name | Phosphatidylinositol 4-kinase type 2 beta |
| Gene symbol | PI4K2B |
| Synonyms (NCBI Gene) |
PI4KIIBPIK42B
|
| Chromosome | 4 |
| Chromosome location | 4p15.2 |
| Summary | This gene encodes a member of the type II PI4 kinase protein family. The encoded protein is primarily cytosolic and contributes to overall PI4-kinase activity along with other protein family members. This protein is involved in early T cell activation. [p |
|
miRNA
miRNA information provided by mirtarbase database.
415
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
34
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q8TCG2 | ||||||||||
| Protein name | Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) (PI4KII-BETA) | ||||||||||
| Protein function | Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell (PubMed:11923287, PubMed:12324459). This contribution may be especially significant in plasma membrane, endosomal and G | ||||||||||
| PDB | 4WTV , 8A5X | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:11923287}. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 481 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
3
|
|||||||||||||||||
|
|||||||||||||||||
|
|||||||||||||||||