PI4K2B (phosphatidylinositol 4-kinase type 2 beta)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55300 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphatidylinositol 4-kinase type 2 beta |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PI4K2B |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PI4KIIB, PIK42B |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4p15.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the type II PI4 kinase protein family. The encoded protein is primarily cytosolic and contributes to overall PI4-kinase activity along with other protein family members. This protein is involved in early T cell activation. [p |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q8TCG2 | ||||||||||
Protein name | Phosphatidylinositol 4-kinase type 2-beta (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-beta) (PI4KII-BETA) | ||||||||||
Protein function | Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell (PubMed:11923287, PubMed:12324459). This contribution may be especially significant in plasma membrane, endosomal and G | ||||||||||
PDB | 4WTV , 8A5X | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:11923287}. | ||||||||||
Sequence |
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Sequence length | 481 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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