FGGY (FGGY carbohydrate kinase domain containing)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55277
Gene name Gene Name - the full gene name approved by the HGNC.
FGGY carbohydrate kinase domain containing
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FGGY
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p32.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sc
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT029931 hsa-miR-26b-5p Microarray 19088304
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0005575 Component Cellular_component ND
GO:0019150 Function D-ribulokinase activity IDA 27909055
GO:0019321 Process Pentose metabolic process IDA 27909055
GO:0019321 Process Pentose metabolic process IMP 27909055
GO:0046835 Process Carbohydrate phosphorylation IDA 27909055
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
611370 25610 ENSG00000172456
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q96C11
Protein name FGGY carbohydrate kinase domain-containing protein (D-ribulokinase FGGY) (EC 2.7.1.47)
Protein function Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activitie
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00370 FGGY_N 11 → 267 FGGY family of carbohydrate kinases, N-terminal domain Domain
PF02782 FGGY_C 289 → 497 FGGY family of carbohydrate kinases, C-terminal domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level). {ECO:0000269|PubMed:17671248}.
Sequence
Sequence length 551
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Pentose and glucuronate interconversions
Metabolic pathways 		 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)		 29220483
Show/Hide Unknown Diseases (3)
Unknown
Disease term Disease name Evidence References Source
Hypertension Hypertension GWAS
Astrocytoma Astrocytoma GWAS
Coronary artery disease Coronary artery disease GWAS
Show/Hide Text Mining Associations (4)
Associations from Text Mining
Disease Name Relationship Type References
Aneuploidy Associate 35347416
Carcinoma Renal Cell Associate 33510822
COVID 19 Associate 35866388
Neoplasms Inhibit 36089125