Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
55147
Gene name Gene Name - the full gene name approved by the HGNC.
RNA binding motif protein 23
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RBM23
Synonyms (NCBI Gene) Gene synonyms aliases
CAPERbeta, PP239, RNPC4
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q11.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptio
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT048779 hsa-miR-93-5p CLASH 23622248
MIRT609235 hsa-miR-8485 HITS-CLIP 19536157
MIRT609233 hsa-miR-377-3p HITS-CLIP 19536157
MIRT549704 hsa-miR-6768-5p HITS-CLIP 21572407
MIRT277920 hsa-miR-5011-5p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 22365833, 23455924, 23602568, 25416956
GO:0005634 Component Nucleus IEA
GO:0006397 Process MRNA processing IEA
GO:0008380 Process RNA splicing IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
621023 20155 ENSG00000100461
Protein
UniProt ID Q86U06
Protein name Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)
Protein function RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor (PubMed:15694343). Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity (PubMed:15694343)
PDB 2CQ4 , 2DNZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 168 236 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 265 335 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF15519 RBM39linker 353 439 linker between RRM2 and RRM3 domains in RBM39 protein Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in placenta, liver, skeletal muscle, heart and kidney (PubMed:15694343). Expressed at lower levels in the colon, thymus, spleen, small intestine and lung (PubMed:15694343). {ECO:0000269|PubMed:15694343}.
Sequence
MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK
KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR
DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPI
IVQA
SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
GRSKGYGFITFSDSECARRALEQLNGFELAGRPMR
VGHVTERLDGGTDITFPDGDQELDL
GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
LNLASQCFQLSSLFTPQTM
Sequence length 439
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
31374203
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 33791378