RBM23 (RNA binding motif protein 23)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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55147 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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RNA binding motif protein 23 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RBM23 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CAPERbeta, PP239, RNPC4 |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptio |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q86U06 | ||||||||||||||||||||
Protein name | Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2) | ||||||||||||||||||||
Protein function | RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor (PubMed:15694343). Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity (PubMed:15694343) | ||||||||||||||||||||
PDB | 2CQ4 , 2DNZ | ||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in placenta, liver, skeletal muscle, heart and kidney (PubMed:15694343). Expressed at lower levels in the colon, thymus, spleen, small intestine and lung (PubMed:15694343). {ECO:0000269|PubMed:15694343}. | ||||||||||||||||||||
Sequence |
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Sequence length | 439 | ||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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