Gene Gene information from NCBI Gene database.
Entrez ID 55147
Gene name RNA binding motif protein 23
Gene symbol RBM23
Synonyms (NCBI Gene)
CAPERbetaPP239RNPC4
Chromosome 14
Chromosome location 14q11.2
Summary This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptio
miRNA miRNA information provided by mirtarbase database.
810
miRTarBase ID miRNA Experiments Reference
MIRT048779 hsa-miR-93-5p CLASH 23622248
MIRT609235 hsa-miR-8485 HITS-CLIP 19536157
MIRT609233 hsa-miR-377-3p HITS-CLIP 19536157
MIRT549704 hsa-miR-6768-5p HITS-CLIP 21572407
MIRT277920 hsa-miR-5011-5p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 22365833, 23455924, 23602568, 25416956, 33961781
GO:0005634 Component Nucleus IEA
GO:0006397 Process MRNA processing IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
621023 20155 ENSG00000100461
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86U06
Protein name Probable RNA-binding protein 23 (CAPER beta) (CAPERbeta) (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)
Protein function RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor (PubMed:15694343). Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity (PubMed:15694343)
PDB 2CQ4 , 2DNZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 168 236 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 265 335 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF15519 RBM39linker 353 439 linker between RRM2 and RRM3 domains in RBM39 protein Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in placenta, liver, skeletal muscle, heart and kidney (PubMed:15694343). Expressed at lower levels in the colon, thymus, spleen, small intestine and lung (PubMed:15694343). {ECO:0000269|PubMed:15694343}.
Sequence
MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK
KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR
DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPI
IVQA
SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
GRSKGYGFITFSDSECARRALEQLNGFELAGRPMR
VGHVTERLDGGTDITFPDGDQELDL
GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
LNLASQCFQLSSLFTPQTM
Sequence length 439
Interactions View interactions