EPDR1 (ependymin related 1)

Gene

• Entrez ID: 54749
• Gene name: Ependymin related 1
• Gene symbol: EPDR1
• Synonyms (NCBI Gene): EPDR, MERP-1, MERP1, UCC1
• Chromosome: 7
• Chromosome location: 7p14.1
• Summary: The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylate

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016452	hsa-miR-193b-3p	Microarray	20304954
MIRT022804	hsa-miR-124-3p	Microarray	18668037
MIRT024408	hsa-miR-215-5p	Microarray	19074876
MIRT026718	hsa-miR-192-5p	Microarray	19074876
MIRT040027	hsa-miR-615-3p	CLASH	23622248
MIRT697030	hsa-miR-3129-3p	HITS-CLIP	23313552
MIRT697029	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT697028	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT697027	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT697026	hsa-miR-5692b	HITS-CLIP	23313552
MIRT697025	hsa-miR-5692c	HITS-CLIP	23313552
MIRT697024	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT697023	hsa-miR-1976	HITS-CLIP	23313552
MIRT221895	hsa-miR-4490	HITS-CLIP	23313552
MIRT697022	hsa-miR-597-5p	HITS-CLIP	23313552
MIRT697021	hsa-miR-374a-5p	HITS-CLIP	23313552
MIRT697020	hsa-miR-374b-5p	HITS-CLIP	23313552
MIRT697019	hsa-miR-4279	HITS-CLIP	23313552
MIRT697018	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT697030	hsa-miR-3129-3p	HITS-CLIP	23313552
MIRT697029	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT697028	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT697027	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT697026	hsa-miR-5692b	HITS-CLIP	23313552
MIRT697025	hsa-miR-5692c	HITS-CLIP	23313552
MIRT697024	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT697023	hsa-miR-1976	HITS-CLIP	23313552
MIRT221895	hsa-miR-4490	HITS-CLIP	23313552
MIRT697022	hsa-miR-597-5p	HITS-CLIP	23313552
MIRT697021	hsa-miR-374a-5p	HITS-CLIP	23313552
MIRT697020	hsa-miR-374b-5p	HITS-CLIP	23313552
MIRT697019	hsa-miR-4279	HITS-CLIP	23313552
MIRT697018	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT966099	hsa-miR-1179	CLIP-seq
MIRT966100	hsa-miR-1237	CLIP-seq
MIRT966101	hsa-miR-1248	CLIP-seq
MIRT966102	hsa-miR-1271	CLIP-seq
MIRT966103	hsa-miR-129-5p	CLIP-seq
MIRT966104	hsa-miR-182	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT966107	hsa-miR-374a	CLIP-seq
MIRT966108	hsa-miR-374b	CLIP-seq
MIRT966109	hsa-miR-377	CLIP-seq
MIRT966110	hsa-miR-4445	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT966112	hsa-miR-4528	CLIP-seq
MIRT966113	hsa-miR-4768-5p	CLIP-seq
MIRT966114	hsa-miR-4799-5p	CLIP-seq
MIRT966115	hsa-miR-515-5p	CLIP-seq
MIRT966116	hsa-miR-579	CLIP-seq
MIRT966117	hsa-miR-597	CLIP-seq
MIRT966118	hsa-miR-96	CLIP-seq
MIRT1548361	hsa-miR-1324	CLIP-seq
MIRT1548362	hsa-miR-154	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT1548364	hsa-miR-4496	CLIP-seq
MIRT1548365	hsa-miR-4519	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT1986130	hsa-miR-337-3p	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT1986131	hsa-miR-3682-5p	CLIP-seq
MIRT1986132	hsa-miR-3908	CLIP-seq
MIRT1986133	hsa-miR-3942-5p	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT1986135	hsa-miR-4287	CLIP-seq
MIRT1986136	hsa-miR-4469	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT1986138	hsa-miR-4685-3p	CLIP-seq
MIRT1986139	hsa-miR-4703-5p	CLIP-seq
MIRT1986140	hsa-miR-4766-3p	CLIP-seq
MIRT1986141	hsa-miR-556-3p	CLIP-seq
MIRT966099	hsa-miR-1179	CLIP-seq
MIRT2220671	hsa-miR-1207-3p	CLIP-seq
MIRT2220672	hsa-miR-1255a	CLIP-seq
MIRT2220673	hsa-miR-1255b	CLIP-seq
MIRT2220674	hsa-miR-1256	CLIP-seq
MIRT2220675	hsa-miR-1257	CLIP-seq
MIRT2220676	hsa-miR-1323	CLIP-seq
MIRT1548361	hsa-miR-1324	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2220677	hsa-miR-181a	CLIP-seq
MIRT2220678	hsa-miR-181b	CLIP-seq
MIRT2220679	hsa-miR-181c	CLIP-seq
MIRT2220680	hsa-miR-181d	CLIP-seq
MIRT2220681	hsa-miR-18a	CLIP-seq
MIRT2220682	hsa-miR-18b	CLIP-seq
MIRT2220683	hsa-miR-1909	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT2220687	hsa-miR-23a	CLIP-seq
MIRT2220688	hsa-miR-23b	CLIP-seq
MIRT2220689	hsa-miR-23c	CLIP-seq
MIRT2220690	hsa-miR-28-5p	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2220692	hsa-miR-3139	CLIP-seq
MIRT2220693	hsa-miR-3140-5p	CLIP-seq
MIRT2220694	hsa-miR-3160-3p	CLIP-seq
MIRT2220695	hsa-miR-3202	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT2220697	hsa-miR-3659	CLIP-seq
MIRT2220698	hsa-miR-3661	CLIP-seq
MIRT2220699	hsa-miR-3670	CLIP-seq
MIRT2220700	hsa-miR-3689a-3p	CLIP-seq
MIRT2220701	hsa-miR-3689c	CLIP-seq
MIRT966109	hsa-miR-377	CLIP-seq
MIRT2220702	hsa-miR-3913-3p	CLIP-seq
MIRT2220703	hsa-miR-421	CLIP-seq
MIRT2220704	hsa-miR-4262	CLIP-seq
MIRT2220705	hsa-miR-4272	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2220706	hsa-miR-4277	CLIP-seq
MIRT2220707	hsa-miR-4282	CLIP-seq
MIRT1986135	hsa-miR-4287	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2220710	hsa-miR-4300	CLIP-seq
MIRT2220711	hsa-miR-4428	CLIP-seq
MIRT2220712	hsa-miR-4470	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT2220713	hsa-miR-4480	CLIP-seq
MIRT2220714	hsa-miR-4487	CLIP-seq
MIRT2220715	hsa-miR-4533	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2220716	hsa-miR-4645-5p	CLIP-seq
MIRT2220717	hsa-miR-4656	CLIP-seq
MIRT2220718	hsa-miR-4658	CLIP-seq
MIRT2220719	hsa-miR-4673	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT1986138	hsa-miR-4685-3p	CLIP-seq
MIRT2220722	hsa-miR-4694-3p	CLIP-seq
MIRT2220723	hsa-miR-4698	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2220725	hsa-miR-4701-5p	CLIP-seq
MIRT2220726	hsa-miR-4708-3p	CLIP-seq
MIRT2220727	hsa-miR-4708-5p	CLIP-seq
MIRT2220728	hsa-miR-4720-5p	CLIP-seq
MIRT2220729	hsa-miR-4731-5p	CLIP-seq
MIRT2220730	hsa-miR-4735-3p	CLIP-seq
MIRT2220731	hsa-miR-4753-3p	CLIP-seq
MIRT2220732	hsa-miR-4761-5p	CLIP-seq
MIRT2220733	hsa-miR-4766-5p	CLIP-seq
MIRT966113	hsa-miR-4768-5p	CLIP-seq
MIRT2220734	hsa-miR-4789-3p	CLIP-seq
MIRT2220735	hsa-miR-4799-3p	CLIP-seq
MIRT2220736	hsa-miR-489	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT966115	hsa-miR-515-5p	CLIP-seq
MIRT2220739	hsa-miR-522	CLIP-seq
MIRT2220740	hsa-miR-539	CLIP-seq
MIRT2220741	hsa-miR-548o	CLIP-seq
MIRT2220742	hsa-miR-550b	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT1986141	hsa-miR-556-3p	CLIP-seq
MIRT2220744	hsa-miR-556-5p	CLIP-seq
MIRT2220745	hsa-miR-558	CLIP-seq
MIRT2220746	hsa-miR-574-5p	CLIP-seq
MIRT2220747	hsa-miR-577	CLIP-seq
MIRT2220748	hsa-miR-581	CLIP-seq
MIRT2220749	hsa-miR-588	CLIP-seq
MIRT2220750	hsa-miR-619	CLIP-seq
MIRT2220751	hsa-miR-631	CLIP-seq
MIRT2220752	hsa-miR-642b	CLIP-seq
MIRT2220753	hsa-miR-708	CLIP-seq
MIRT2220754	hsa-miR-891b	CLIP-seq
MIRT2220755	hsa-miR-920	CLIP-seq
MIRT2220756	hsa-miR-942	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT2524438	hsa-miR-100	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2524439	hsa-miR-153	CLIP-seq
MIRT2524440	hsa-miR-183	CLIP-seq
MIRT2524441	hsa-miR-1973	CLIP-seq
MIRT2524442	hsa-miR-199a-5p	CLIP-seq
MIRT2524443	hsa-miR-199b-5p	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2524444	hsa-miR-217	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2524445	hsa-miR-3159	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2524446	hsa-miR-4280	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2524447	hsa-miR-4320	CLIP-seq
MIRT2524448	hsa-miR-448	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2524449	hsa-miR-4662a-5p	CLIP-seq
MIRT2524450	hsa-miR-4666-5p	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT2524451	hsa-miR-4684-5p	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2524452	hsa-miR-4725-5p	CLIP-seq
MIRT2524453	hsa-miR-4802-3p	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT2524454	hsa-miR-504	CLIP-seq
MIRT2524455	hsa-miR-517b	CLIP-seq
MIRT2524456	hsa-miR-520g	CLIP-seq
MIRT2524457	hsa-miR-520h	CLIP-seq
MIRT2524458	hsa-miR-548aa	CLIP-seq
MIRT2524459	hsa-miR-548g	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT2524460	hsa-miR-651	CLIP-seq
MIRT2524461	hsa-miR-99a	CLIP-seq
MIRT2524462	hsa-miR-99b	CLIP-seq
MIRT2524438	hsa-miR-100	CLIP-seq
MIRT2680155	hsa-miR-101	CLIP-seq
MIRT2680156	hsa-miR-1178	CLIP-seq
MIRT2680157	hsa-miR-1343	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2524439	hsa-miR-153	CLIP-seq
MIRT2524440	hsa-miR-183	CLIP-seq
MIRT2524441	hsa-miR-1973	CLIP-seq
MIRT2524442	hsa-miR-199a-5p	CLIP-seq
MIRT2524443	hsa-miR-199b-5p	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2524444	hsa-miR-217	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2524445	hsa-miR-3159	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT2680158	hsa-miR-371b-5p	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2220706	hsa-miR-4277	CLIP-seq
MIRT2524446	hsa-miR-4280	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2680159	hsa-miR-4312	CLIP-seq
MIRT2524447	hsa-miR-4320	CLIP-seq
MIRT2680160	hsa-miR-4471	CLIP-seq
MIRT2524448	hsa-miR-448	CLIP-seq
MIRT2680161	hsa-miR-4540	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2680162	hsa-miR-4645-3p	CLIP-seq
MIRT2524449	hsa-miR-4662a-5p	CLIP-seq
MIRT2524450	hsa-miR-4666-5p	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT2680163	hsa-miR-4680-5p	CLIP-seq
MIRT2524451	hsa-miR-4684-5p	CLIP-seq
MIRT2220723	hsa-miR-4698	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2524452	hsa-miR-4725-5p	CLIP-seq
MIRT2524453	hsa-miR-4802-3p	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT2524454	hsa-miR-504	CLIP-seq
MIRT2524455	hsa-miR-517b	CLIP-seq
MIRT2524456	hsa-miR-520g	CLIP-seq
MIRT2524457	hsa-miR-520h	CLIP-seq
MIRT2524458	hsa-miR-548aa	CLIP-seq
MIRT2524459	hsa-miR-548g	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT2680164	hsa-miR-618	CLIP-seq
MIRT2680165	hsa-miR-629	CLIP-seq
MIRT2524460	hsa-miR-651	CLIP-seq
MIRT2524461	hsa-miR-99a	CLIP-seq
MIRT2524462	hsa-miR-99b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005543	Function	Phospholipid binding	IPI	30729188
GO:0005576	Component	Extracellular region	IDA	30729188
GO:0005576	Component	Extracellular region	IEA
GO:0005764	Component	Lysosome	IBA
GO:0005764	Component	Lysosome	IDA	30729188
GO:0005764	Component	Lysosome	IEA
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0042802	Function	Identical protein binding	IDA	30729188
GO:0043202	Component	Lysosomal lumen	IEA
GO:1905573	Function	Ganglioside GM1 binding	IDA	30729188
GO:1990764	Process	Myofibroblast contraction	IMP	27245865

Other IDs

• MIM: 619734
• HGNC: 17572
• e!Ensembl: ENSG00000086289

Protein

• UniProt ID: Q9UM22
• Protein name: Mammalian ependymin-related protein 1 (MERP-1) (Upregulated in colorectal cancer gene 1 protein)
• Protein function: Binds anionic lipids and gangliosides at acidic pH.
• PDB: 6E7O, 6E8N, 6JLD
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00811	Ependymin	87 → 210	Ependymin	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. Detected in brain, heart, skeletal muscle, kidney, testis, ovary and prostate. {ECO:0000269|PubMed:11749721}.
• Sequence:

  MPGRAPLRTVPGALGAWLLGGLWAWTLCGLCSLGAVGAPRPCQAPQQWEGRQVMYQQSSG
  RNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQ
  PWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFT
  INYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW

• Sequence length: 224