Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	54749
Gene name Gene Name - the full gene name approved by the HGNC.	Ependymin related 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	EPDR1
Synonyms (NCBI Gene) Gene synonyms aliases	EPDR, MERP-1, MERP1, UCC1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p14.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylate

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016452	hsa-miR-193b-3p	Microarray	20304954
MIRT022804	hsa-miR-124-3p	Microarray	18668037
MIRT024408	hsa-miR-215-5p	Microarray	19074876
MIRT026718	hsa-miR-192-5p	Microarray	19074876
MIRT040027	hsa-miR-615-3p	CLASH	23622248
MIRT697030	hsa-miR-3129-3p	HITS-CLIP	23313552
MIRT697029	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT697028	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT697027	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT697026	hsa-miR-5692b	HITS-CLIP	23313552
MIRT697025	hsa-miR-5692c	HITS-CLIP	23313552
MIRT697024	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT697023	hsa-miR-1976	HITS-CLIP	23313552
MIRT221895	hsa-miR-4490	HITS-CLIP	23313552
MIRT697022	hsa-miR-597-5p	HITS-CLIP	23313552
MIRT697021	hsa-miR-374a-5p	HITS-CLIP	23313552
MIRT697020	hsa-miR-374b-5p	HITS-CLIP	23313552
MIRT697019	hsa-miR-4279	HITS-CLIP	23313552
MIRT697018	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT697030	hsa-miR-3129-3p	HITS-CLIP	23313552
MIRT697029	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT697028	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT697027	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT697026	hsa-miR-5692b	HITS-CLIP	23313552
MIRT697025	hsa-miR-5692c	HITS-CLIP	23313552
MIRT697024	hsa-miR-3653-5p	HITS-CLIP	23313552
MIRT697023	hsa-miR-1976	HITS-CLIP	23313552
MIRT221895	hsa-miR-4490	HITS-CLIP	23313552
MIRT697022	hsa-miR-597-5p	HITS-CLIP	23313552
MIRT697021	hsa-miR-374a-5p	HITS-CLIP	23313552
MIRT697020	hsa-miR-374b-5p	HITS-CLIP	23313552
MIRT697019	hsa-miR-4279	HITS-CLIP	23313552
MIRT697018	hsa-miR-629-3p	HITS-CLIP	23313552
MIRT966099	hsa-miR-1179	CLIP-seq
MIRT966100	hsa-miR-1237	CLIP-seq
MIRT966101	hsa-miR-1248	CLIP-seq
MIRT966102	hsa-miR-1271	CLIP-seq
MIRT966103	hsa-miR-129-5p	CLIP-seq
MIRT966104	hsa-miR-182	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT966107	hsa-miR-374a	CLIP-seq
MIRT966108	hsa-miR-374b	CLIP-seq
MIRT966109	hsa-miR-377	CLIP-seq
MIRT966110	hsa-miR-4445	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT966112	hsa-miR-4528	CLIP-seq
MIRT966113	hsa-miR-4768-5p	CLIP-seq
MIRT966114	hsa-miR-4799-5p	CLIP-seq
MIRT966115	hsa-miR-515-5p	CLIP-seq
MIRT966116	hsa-miR-579	CLIP-seq
MIRT966117	hsa-miR-597	CLIP-seq
MIRT966118	hsa-miR-96	CLIP-seq
MIRT1548361	hsa-miR-1324	CLIP-seq
MIRT1548362	hsa-miR-154	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT1548364	hsa-miR-4496	CLIP-seq
MIRT1548365	hsa-miR-4519	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT1986130	hsa-miR-337-3p	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT1986131	hsa-miR-3682-5p	CLIP-seq
MIRT1986132	hsa-miR-3908	CLIP-seq
MIRT1986133	hsa-miR-3942-5p	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT1986135	hsa-miR-4287	CLIP-seq
MIRT1986136	hsa-miR-4469	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT1986138	hsa-miR-4685-3p	CLIP-seq
MIRT1986139	hsa-miR-4703-5p	CLIP-seq
MIRT1986140	hsa-miR-4766-3p	CLIP-seq
MIRT1986141	hsa-miR-556-3p	CLIP-seq
MIRT966099	hsa-miR-1179	CLIP-seq
MIRT2220671	hsa-miR-1207-3p	CLIP-seq
MIRT2220672	hsa-miR-1255a	CLIP-seq
MIRT2220673	hsa-miR-1255b	CLIP-seq
MIRT2220674	hsa-miR-1256	CLIP-seq
MIRT2220675	hsa-miR-1257	CLIP-seq
MIRT2220676	hsa-miR-1323	CLIP-seq
MIRT1548361	hsa-miR-1324	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2220677	hsa-miR-181a	CLIP-seq
MIRT2220678	hsa-miR-181b	CLIP-seq
MIRT2220679	hsa-miR-181c	CLIP-seq
MIRT2220680	hsa-miR-181d	CLIP-seq
MIRT2220681	hsa-miR-18a	CLIP-seq
MIRT2220682	hsa-miR-18b	CLIP-seq
MIRT2220683	hsa-miR-1909	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT2220687	hsa-miR-23a	CLIP-seq
MIRT2220688	hsa-miR-23b	CLIP-seq
MIRT2220689	hsa-miR-23c	CLIP-seq
MIRT2220690	hsa-miR-28-5p	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2220692	hsa-miR-3139	CLIP-seq
MIRT2220693	hsa-miR-3140-5p	CLIP-seq
MIRT2220694	hsa-miR-3160-3p	CLIP-seq
MIRT2220695	hsa-miR-3202	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT966106	hsa-miR-345	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT2220697	hsa-miR-3659	CLIP-seq
MIRT2220698	hsa-miR-3661	CLIP-seq
MIRT2220699	hsa-miR-3670	CLIP-seq
MIRT2220700	hsa-miR-3689a-3p	CLIP-seq
MIRT2220701	hsa-miR-3689c	CLIP-seq
MIRT966109	hsa-miR-377	CLIP-seq
MIRT2220702	hsa-miR-3913-3p	CLIP-seq
MIRT2220703	hsa-miR-421	CLIP-seq
MIRT2220704	hsa-miR-4262	CLIP-seq
MIRT2220705	hsa-miR-4272	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2220706	hsa-miR-4277	CLIP-seq
MIRT2220707	hsa-miR-4282	CLIP-seq
MIRT1986135	hsa-miR-4287	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2220710	hsa-miR-4300	CLIP-seq
MIRT2220711	hsa-miR-4428	CLIP-seq
MIRT2220712	hsa-miR-4470	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT2220713	hsa-miR-4480	CLIP-seq
MIRT2220714	hsa-miR-4487	CLIP-seq
MIRT2220715	hsa-miR-4533	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2220716	hsa-miR-4645-5p	CLIP-seq
MIRT2220717	hsa-miR-4656	CLIP-seq
MIRT2220718	hsa-miR-4658	CLIP-seq
MIRT2220719	hsa-miR-4673	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT1986138	hsa-miR-4685-3p	CLIP-seq
MIRT2220722	hsa-miR-4694-3p	CLIP-seq
MIRT2220723	hsa-miR-4698	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2220725	hsa-miR-4701-5p	CLIP-seq
MIRT2220726	hsa-miR-4708-3p	CLIP-seq
MIRT2220727	hsa-miR-4708-5p	CLIP-seq
MIRT2220728	hsa-miR-4720-5p	CLIP-seq
MIRT2220729	hsa-miR-4731-5p	CLIP-seq
MIRT2220730	hsa-miR-4735-3p	CLIP-seq
MIRT2220731	hsa-miR-4753-3p	CLIP-seq
MIRT2220732	hsa-miR-4761-5p	CLIP-seq
MIRT2220733	hsa-miR-4766-5p	CLIP-seq
MIRT966113	hsa-miR-4768-5p	CLIP-seq
MIRT2220734	hsa-miR-4789-3p	CLIP-seq
MIRT2220735	hsa-miR-4799-3p	CLIP-seq
MIRT2220736	hsa-miR-489	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT966115	hsa-miR-515-5p	CLIP-seq
MIRT2220739	hsa-miR-522	CLIP-seq
MIRT2220740	hsa-miR-539	CLIP-seq
MIRT2220741	hsa-miR-548o	CLIP-seq
MIRT2220742	hsa-miR-550b	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT1986141	hsa-miR-556-3p	CLIP-seq
MIRT2220744	hsa-miR-556-5p	CLIP-seq
MIRT2220745	hsa-miR-558	CLIP-seq
MIRT2220746	hsa-miR-574-5p	CLIP-seq
MIRT2220747	hsa-miR-577	CLIP-seq
MIRT2220748	hsa-miR-581	CLIP-seq
MIRT2220749	hsa-miR-588	CLIP-seq
MIRT2220750	hsa-miR-619	CLIP-seq
MIRT2220751	hsa-miR-631	CLIP-seq
MIRT2220752	hsa-miR-642b	CLIP-seq
MIRT2220753	hsa-miR-708	CLIP-seq
MIRT2220754	hsa-miR-891b	CLIP-seq
MIRT2220755	hsa-miR-920	CLIP-seq
MIRT2220756	hsa-miR-942	CLIP-seq
MIRT966111	hsa-miR-4474-5p	CLIP-seq
MIRT2524438	hsa-miR-100	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2524439	hsa-miR-153	CLIP-seq
MIRT2524440	hsa-miR-183	CLIP-seq
MIRT2524441	hsa-miR-1973	CLIP-seq
MIRT2524442	hsa-miR-199a-5p	CLIP-seq
MIRT2524443	hsa-miR-199b-5p	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2524444	hsa-miR-217	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2524445	hsa-miR-3159	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2524446	hsa-miR-4280	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2524447	hsa-miR-4320	CLIP-seq
MIRT2524448	hsa-miR-448	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2524449	hsa-miR-4662a-5p	CLIP-seq
MIRT2524450	hsa-miR-4666-5p	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT2524451	hsa-miR-4684-5p	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2524452	hsa-miR-4725-5p	CLIP-seq
MIRT2524453	hsa-miR-4802-3p	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT2524454	hsa-miR-504	CLIP-seq
MIRT2524455	hsa-miR-517b	CLIP-seq
MIRT2524456	hsa-miR-520g	CLIP-seq
MIRT2524457	hsa-miR-520h	CLIP-seq
MIRT2524458	hsa-miR-548aa	CLIP-seq
MIRT2524459	hsa-miR-548g	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT2524460	hsa-miR-651	CLIP-seq
MIRT2524461	hsa-miR-99a	CLIP-seq
MIRT2524462	hsa-miR-99b	CLIP-seq
MIRT2524438	hsa-miR-100	CLIP-seq
MIRT2680155	hsa-miR-101	CLIP-seq
MIRT2680156	hsa-miR-1178	CLIP-seq
MIRT2680157	hsa-miR-1343	CLIP-seq
MIRT1986127	hsa-miR-148a	CLIP-seq
MIRT1986128	hsa-miR-148b	CLIP-seq
MIRT1986129	hsa-miR-152	CLIP-seq
MIRT2524439	hsa-miR-153	CLIP-seq
MIRT2524440	hsa-miR-183	CLIP-seq
MIRT2524441	hsa-miR-1973	CLIP-seq
MIRT2524442	hsa-miR-199a-5p	CLIP-seq
MIRT2524443	hsa-miR-199b-5p	CLIP-seq
MIRT2220684	hsa-miR-200b	CLIP-seq
MIRT2220685	hsa-miR-200c	CLIP-seq
MIRT2524444	hsa-miR-217	CLIP-seq
MIRT2220686	hsa-miR-223	CLIP-seq
MIRT1548363	hsa-miR-298	CLIP-seq
MIRT2220691	hsa-miR-3065-3p	CLIP-seq
MIRT2524445	hsa-miR-3159	CLIP-seq
MIRT966105	hsa-miR-339-5p	CLIP-seq
MIRT2220696	hsa-miR-3611	CLIP-seq
MIRT2680158	hsa-miR-371b-5p	CLIP-seq
MIRT1986134	hsa-miR-4276	CLIP-seq
MIRT2220706	hsa-miR-4277	CLIP-seq
MIRT2524446	hsa-miR-4280	CLIP-seq
MIRT2220708	hsa-miR-429	CLIP-seq
MIRT2220709	hsa-miR-4291	CLIP-seq
MIRT2680159	hsa-miR-4312	CLIP-seq
MIRT2524447	hsa-miR-4320	CLIP-seq
MIRT2680160	hsa-miR-4471	CLIP-seq
MIRT2524448	hsa-miR-448	CLIP-seq
MIRT2680161	hsa-miR-4540	CLIP-seq
MIRT1986137	hsa-miR-455-5p	CLIP-seq
MIRT2680162	hsa-miR-4645-3p	CLIP-seq
MIRT2524449	hsa-miR-4662a-5p	CLIP-seq
MIRT2524450	hsa-miR-4666-5p	CLIP-seq
MIRT2220720	hsa-miR-4677-3p	CLIP-seq
MIRT2220721	hsa-miR-4679	CLIP-seq
MIRT2680163	hsa-miR-4680-5p	CLIP-seq
MIRT2524451	hsa-miR-4684-5p	CLIP-seq
MIRT2220723	hsa-miR-4698	CLIP-seq
MIRT2220724	hsa-miR-4699-5p	CLIP-seq
MIRT2524452	hsa-miR-4725-5p	CLIP-seq
MIRT2524453	hsa-miR-4802-3p	CLIP-seq
MIRT2220737	hsa-miR-499-3p	CLIP-seq
MIRT2220738	hsa-miR-499a-3p	CLIP-seq
MIRT2524454	hsa-miR-504	CLIP-seq
MIRT2524455	hsa-miR-517b	CLIP-seq
MIRT2524456	hsa-miR-520g	CLIP-seq
MIRT2524457	hsa-miR-520h	CLIP-seq
MIRT2524458	hsa-miR-548aa	CLIP-seq
MIRT2524459	hsa-miR-548g	CLIP-seq
MIRT2220743	hsa-miR-554	CLIP-seq
MIRT2680164	hsa-miR-618	CLIP-seq
MIRT2680165	hsa-miR-629	CLIP-seq
MIRT2524460	hsa-miR-651	CLIP-seq
MIRT2524461	hsa-miR-99a	CLIP-seq
MIRT2524462	hsa-miR-99b	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005543	Function	Phospholipid binding	IPI	30729188
GO:0005576	Component	Extracellular region	IDA	30729188
GO:0005764	Component	Lysosome	IBA	21873635
GO:0005764	Component	Lysosome	IDA	30729188
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0042802	Function	Identical protein binding	IDA	30729188
GO:0043202	Component	Lysosomal lumen	IEA
GO:1905573	Function	Ganglioside GM1 binding	IDA	30729188
GO:1990764	Process	Myofibroblast contraction	IMP	27245865

MIM	HGNC	e!Ensembl
619734	17572	ENSG00000086289

Protein

UniProt ID

Q9UM22

Protein name

Mammalian ependymin-related protein 1 (MERP-1) (Upregulated in colorectal cancer gene 1 protein)

Protein function

Binds anionic lipids and gangliosides at acidic pH.

PDB

6E7O , 6E8N , 6JLD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00811	Ependymin	87 → 210	Ependymin	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Detected in brain, heart, skeletal muscle, kidney, testis, ovary and prostate. {ECO:0000269|PubMed:11749721}.

Sequence

MPGRAPLRTVPGALGAWLLGGLWAWTLCGLCSLGAVGAPRPCQAPQQWEGRQVMYQQSSG
RNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQ
PWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFT
INYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW

Sequence length

224

Interactions

View interactions

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039 View all (65 more)	24162737, 30617256
Ciliary dyskinesia	Ciliary Motility Disorders	rs397515339, rs267607225, rs267607226, rs786205052, rs267607227, rs118204041, rs118204042, rs118204043, rs137853191, rs121434369, rs397515565, rs397515358, rs137852998, rs397515363, rs79833450 View all (813 more)
Pyle metaphyseal dysplasia	Pyle metaphyseal dysplasia	rs879255603, rs755007671, rs879253778

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	38308220
Carcinoma Hepatocellular	Associate	32935479
Cleft Lip	Associate	34024335
Colorectal Neoplasms	Associate	32111877
Coronary Artery Disease	Associate	32710445
Diabetes Mellitus Type 2	Stimulate	36343918
Dupuytren Contracture	Associate	21732829
Dysautonomia Familial	Stimulate	22252855
Hypoxia	Associate	38308220
Hypoxia Brain	Associate	38308220
Immunoglobulin Light chain Amyloidosis	Associate	32922167
Lung Neoplasms	Associate	35101137
Multiple Myeloma	Associate	32922167
Neoplasm Metastasis	Associate	33902536
Neoplasms	Stimulate	22252855
Neoplasms	Associate	32111877, 32935479, 33902536
Norrie disease	Associate	22252855
Obesity	Stimulate	36343918
Ovarian Neoplasms	Associate	34218800
Urinary Bladder Neoplasms	Associate	33902536

EPDR1 (ependymin related 1)