Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5469
Gene name Gene Name - the full gene name approved by the HGNC.	Mediator complex subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MED1
Synonyms (NCBI Gene) Gene synonyms aliases	CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q12
Summary Summary of gene provided in NCBI Entrez Gene.	The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. T

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003239	hsa-miR-205-5p	Luciferase reporter assay, Western blot	20065103
MIRT003239	hsa-miR-205-5p	Luciferase reporter assay, Western blot	20065103
MIRT003239	hsa-miR-205-5p	Luciferase reporter assay, Western blot	20065103
MIRT027932	hsa-miR-96-5p	Sequencing	20371350
MIRT047844	hsa-miR-30c-5p	CLASH	23622248
MIRT047640	hsa-miR-10a-5p	CLASH	23622248
MIRT046058	hsa-miR-125b-5p	CLASH	23622248
MIRT003239	hsa-miR-205-5p	qRT-PCR, Western blot	22869146
MIRT003239	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT003239	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT1140270	hsa-miR-1207-5p	CLIP-seq
MIRT1140271	hsa-miR-1257	CLIP-seq
MIRT1140272	hsa-miR-125a-5p	CLIP-seq
MIRT1140273	hsa-miR-125b	CLIP-seq
MIRT1140274	hsa-miR-1266	CLIP-seq
MIRT1140275	hsa-miR-1273d	CLIP-seq
MIRT1140276	hsa-miR-1912	CLIP-seq
MIRT1140277	hsa-miR-217	CLIP-seq
MIRT1140278	hsa-miR-221	CLIP-seq
MIRT1140279	hsa-miR-222	CLIP-seq
MIRT1140280	hsa-miR-2278	CLIP-seq
MIRT1140281	hsa-miR-3119	CLIP-seq
MIRT1140282	hsa-miR-3158-3p	CLIP-seq
MIRT1140283	hsa-miR-3611	CLIP-seq
MIRT1140284	hsa-miR-3664-3p	CLIP-seq
MIRT1140285	hsa-miR-376c	CLIP-seq
MIRT1140286	hsa-miR-3913-3p	CLIP-seq
MIRT1140287	hsa-miR-3924	CLIP-seq
MIRT1140288	hsa-miR-3940-5p	CLIP-seq
MIRT1140289	hsa-miR-409-3p	CLIP-seq
MIRT1140290	hsa-miR-4251	CLIP-seq
MIRT1140291	hsa-miR-4252	CLIP-seq
MIRT1140292	hsa-miR-4269	CLIP-seq
MIRT1140293	hsa-miR-4303	CLIP-seq
MIRT1140294	hsa-miR-4319	CLIP-seq
MIRT1140295	hsa-miR-4329	CLIP-seq
MIRT1140296	hsa-miR-433	CLIP-seq
MIRT1140297	hsa-miR-4418	CLIP-seq
MIRT1140298	hsa-miR-4476	CLIP-seq
MIRT1140299	hsa-miR-4507	CLIP-seq
MIRT1140300	hsa-miR-4514	CLIP-seq
MIRT1140301	hsa-miR-4518	CLIP-seq
MIRT1140302	hsa-miR-4692	CLIP-seq
MIRT1140303	hsa-miR-4704-5p	CLIP-seq
MIRT1140304	hsa-miR-4732-3p	CLIP-seq
MIRT1140305	hsa-miR-4733-5p	CLIP-seq
MIRT1140306	hsa-miR-4742-5p	CLIP-seq
MIRT1140307	hsa-miR-4760-3p	CLIP-seq
MIRT1140308	hsa-miR-4763-3p	CLIP-seq
MIRT1140309	hsa-miR-4764-3p	CLIP-seq
MIRT1140310	hsa-miR-4766-5p	CLIP-seq
MIRT1140311	hsa-miR-488	CLIP-seq
MIRT1140312	hsa-miR-489	CLIP-seq
MIRT1140313	hsa-miR-499-3p	CLIP-seq
MIRT1140314	hsa-miR-499a-3p	CLIP-seq
MIRT1140315	hsa-miR-501-3p	CLIP-seq
MIRT1140316	hsa-miR-502-3p	CLIP-seq
MIRT1140317	hsa-miR-509-3-5p	CLIP-seq
MIRT1140318	hsa-miR-509-5p	CLIP-seq
MIRT1140319	hsa-miR-515-5p	CLIP-seq
MIRT1140320	hsa-miR-548aa	CLIP-seq
MIRT1140321	hsa-miR-548v	CLIP-seq
MIRT1140322	hsa-miR-570	CLIP-seq
MIRT1140323	hsa-miR-580	CLIP-seq
MIRT1140324	hsa-miR-618	CLIP-seq
MIRT1140325	hsa-miR-659	CLIP-seq
MIRT1140326	hsa-miR-670	CLIP-seq
MIRT1140327	hsa-miR-676	CLIP-seq
MIRT1140328	hsa-miR-873	CLIP-seq
MIRT1140329	hsa-miR-940	CLIP-seq
MIRT2039764	hsa-miR-1226	CLIP-seq
MIRT1140271	hsa-miR-1257	CLIP-seq
MIRT2039765	hsa-miR-128	CLIP-seq
MIRT2039766	hsa-miR-146a	CLIP-seq
MIRT2039767	hsa-miR-146b-5p	CLIP-seq
MIRT2039768	hsa-miR-148a	CLIP-seq
MIRT2039769	hsa-miR-148b	CLIP-seq
MIRT2039770	hsa-miR-152	CLIP-seq
MIRT2039771	hsa-miR-15a	CLIP-seq
MIRT2039772	hsa-miR-15b	CLIP-seq
MIRT2039773	hsa-miR-16	CLIP-seq
MIRT2039774	hsa-miR-1913	CLIP-seq
MIRT2039775	hsa-miR-195	CLIP-seq
MIRT2039776	hsa-miR-196a	CLIP-seq
MIRT2039777	hsa-miR-196b	CLIP-seq
MIRT2039778	hsa-miR-205	CLIP-seq
MIRT2039779	hsa-miR-2052	CLIP-seq
MIRT2039780	hsa-miR-2355-3p	CLIP-seq
MIRT2039781	hsa-miR-298	CLIP-seq
MIRT1140281	hsa-miR-3119	CLIP-seq
MIRT2039782	hsa-miR-3160-3p	CLIP-seq
MIRT2039783	hsa-miR-3190	CLIP-seq
MIRT2039784	hsa-miR-324-3p	CLIP-seq
MIRT2039785	hsa-miR-335	CLIP-seq
MIRT2039786	hsa-miR-3591-5p	CLIP-seq
MIRT1140283	hsa-miR-3611	CLIP-seq
MIRT2039787	hsa-miR-3617	CLIP-seq
MIRT2039788	hsa-miR-3622a-3p	CLIP-seq
MIRT2039789	hsa-miR-3622b-3p	CLIP-seq
MIRT2039790	hsa-miR-3662	CLIP-seq
MIRT2039791	hsa-miR-3685	CLIP-seq
MIRT2039792	hsa-miR-384	CLIP-seq
MIRT1140286	hsa-miR-3913-3p	CLIP-seq
MIRT2039793	hsa-miR-3927	CLIP-seq
MIRT1140289	hsa-miR-409-3p	CLIP-seq
MIRT2039794	hsa-miR-424	CLIP-seq
MIRT2039795	hsa-miR-4279	CLIP-seq
MIRT2039796	hsa-miR-4286	CLIP-seq
MIRT2039797	hsa-miR-4289	CLIP-seq
MIRT2039798	hsa-miR-4307	CLIP-seq
MIRT2039799	hsa-miR-4318	CLIP-seq
MIRT2039800	hsa-miR-4320	CLIP-seq
MIRT2039801	hsa-miR-4502	CLIP-seq
MIRT2039802	hsa-miR-4530	CLIP-seq
MIRT2039803	hsa-miR-4646-3p	CLIP-seq
MIRT2039804	hsa-miR-4650-3p	CLIP-seq
MIRT2039805	hsa-miR-4662a-3p	CLIP-seq
MIRT1140303	hsa-miR-4704-5p	CLIP-seq
MIRT2039806	hsa-miR-4727-5p	CLIP-seq
MIRT2039807	hsa-miR-4752	CLIP-seq
MIRT2039808	hsa-miR-4778-5p	CLIP-seq
MIRT1140312	hsa-miR-489	CLIP-seq
MIRT2039809	hsa-miR-497	CLIP-seq
MIRT2039810	hsa-miR-498	CLIP-seq
MIRT2039811	hsa-miR-500a	CLIP-seq
MIRT2039812	hsa-miR-544	CLIP-seq
MIRT1140322	hsa-miR-570	CLIP-seq
MIRT2039813	hsa-miR-597	CLIP-seq
MIRT2039814	hsa-miR-634	CLIP-seq
MIRT2039815	hsa-miR-641	CLIP-seq
MIRT2039816	hsa-miR-653	CLIP-seq
MIRT1140327	hsa-miR-676	CLIP-seq
MIRT1140328	hsa-miR-873	CLIP-seq
MIRT2039817	hsa-miR-922	CLIP-seq
MIRT2269534	hsa-miR-1	CLIP-seq
MIRT2269535	hsa-miR-101	CLIP-seq
MIRT2269536	hsa-miR-105	CLIP-seq
MIRT2269537	hsa-miR-10a	CLIP-seq
MIRT2269538	hsa-miR-10b	CLIP-seq
MIRT2269539	hsa-miR-1178	CLIP-seq
MIRT2269540	hsa-miR-1179	CLIP-seq
MIRT2269541	hsa-miR-1182	CLIP-seq
MIRT2269542	hsa-miR-1183	CLIP-seq
MIRT1140270	hsa-miR-1207-5p	CLIP-seq
MIRT2269543	hsa-miR-122	CLIP-seq
MIRT2269544	hsa-miR-1225-3p	CLIP-seq
MIRT2039764	hsa-miR-1226	CLIP-seq
MIRT2269545	hsa-miR-1233	CLIP-seq
MIRT2269546	hsa-miR-1234	CLIP-seq
MIRT2269547	hsa-miR-1245b-3p	CLIP-seq
MIRT2269548	hsa-miR-1248	CLIP-seq
MIRT1140271	hsa-miR-1257	CLIP-seq
MIRT1140272	hsa-miR-125a-5p	CLIP-seq
MIRT1140273	hsa-miR-125b	CLIP-seq
MIRT1140274	hsa-miR-1266	CLIP-seq
MIRT2269549	hsa-miR-1267	CLIP-seq
MIRT2269550	hsa-miR-1271	CLIP-seq
MIRT2269551	hsa-miR-1272	CLIP-seq
MIRT2269552	hsa-miR-1273e	CLIP-seq
MIRT2039765	hsa-miR-128	CLIP-seq
MIRT2269553	hsa-miR-1290	CLIP-seq
MIRT2269554	hsa-miR-1291	CLIP-seq
MIRT2269555	hsa-miR-132	CLIP-seq
MIRT2269556	hsa-miR-1321	CLIP-seq
MIRT2269557	hsa-miR-1322	CLIP-seq
MIRT2269558	hsa-miR-1323	CLIP-seq
MIRT2269559	hsa-miR-1343	CLIP-seq
MIRT2269560	hsa-miR-135a	CLIP-seq
MIRT2269561	hsa-miR-135b	CLIP-seq
MIRT2269562	hsa-miR-139-5p	CLIP-seq
MIRT2269563	hsa-miR-144	CLIP-seq
MIRT2039766	hsa-miR-146a	CLIP-seq
MIRT2039767	hsa-miR-146b-5p	CLIP-seq
MIRT2039768	hsa-miR-148a	CLIP-seq
MIRT2039769	hsa-miR-148b	CLIP-seq
MIRT2269564	hsa-miR-149	CLIP-seq
MIRT2039770	hsa-miR-152	CLIP-seq
MIRT2269565	hsa-miR-1539	CLIP-seq
MIRT2269566	hsa-miR-154	CLIP-seq
MIRT2269567	hsa-miR-1587	CLIP-seq
MIRT2039771	hsa-miR-15a	CLIP-seq
MIRT2039772	hsa-miR-15b	CLIP-seq
MIRT2039773	hsa-miR-16	CLIP-seq
MIRT2269568	hsa-miR-181a	CLIP-seq
MIRT2269569	hsa-miR-181b	CLIP-seq
MIRT2269570	hsa-miR-181c	CLIP-seq
MIRT2269571	hsa-miR-181d	CLIP-seq
MIRT2269572	hsa-miR-182	CLIP-seq
MIRT2269573	hsa-miR-183	CLIP-seq
MIRT2269574	hsa-miR-1911	CLIP-seq
MIRT2269575	hsa-miR-1915	CLIP-seq
MIRT2039775	hsa-miR-195	CLIP-seq
MIRT2039776	hsa-miR-196a	CLIP-seq
MIRT2039777	hsa-miR-196b	CLIP-seq
MIRT2269576	hsa-miR-1976	CLIP-seq
MIRT2039778	hsa-miR-205	CLIP-seq
MIRT2269577	hsa-miR-206	CLIP-seq
MIRT2269578	hsa-miR-208a	CLIP-seq
MIRT2269579	hsa-miR-208b	CLIP-seq
MIRT2269580	hsa-miR-212	CLIP-seq
MIRT1140277	hsa-miR-217	CLIP-seq
MIRT1140278	hsa-miR-221	CLIP-seq
MIRT1140279	hsa-miR-222	CLIP-seq
MIRT2269581	hsa-miR-224	CLIP-seq
MIRT1140280	hsa-miR-2278	CLIP-seq
MIRT2039780	hsa-miR-2355-3p	CLIP-seq
MIRT2269582	hsa-miR-2964a-5p	CLIP-seq
MIRT2039781	hsa-miR-298	CLIP-seq
MIRT2269583	hsa-miR-299-5p	CLIP-seq
MIRT2269584	hsa-miR-3064-5p	CLIP-seq
MIRT2269585	hsa-miR-3074-5p	CLIP-seq
MIRT2269586	hsa-miR-3120-5p	CLIP-seq
MIRT2269587	hsa-miR-3125	CLIP-seq
MIRT2269588	hsa-miR-3127-5p	CLIP-seq
MIRT2269589	hsa-miR-3140-3p	CLIP-seq
MIRT2269590	hsa-miR-3140-5p	CLIP-seq
MIRT2269591	hsa-miR-3145-3p	CLIP-seq
MIRT2269592	hsa-miR-3145-5p	CLIP-seq
MIRT2269593	hsa-miR-3148	CLIP-seq
MIRT2269594	hsa-miR-3152-5p	CLIP-seq
MIRT1140282	hsa-miR-3158-3p	CLIP-seq
MIRT2269595	hsa-miR-3158-5p	CLIP-seq
MIRT2269596	hsa-miR-3159	CLIP-seq
MIRT2039782	hsa-miR-3160-3p	CLIP-seq
MIRT2269597	hsa-miR-3162-3p	CLIP-seq
MIRT2269598	hsa-miR-3166	CLIP-seq
MIRT2269599	hsa-miR-3167	CLIP-seq
MIRT2269600	hsa-miR-3173-5p	CLIP-seq
MIRT2269601	hsa-miR-3174	CLIP-seq
MIRT2269602	hsa-miR-3179	CLIP-seq
MIRT2269603	hsa-miR-3182	CLIP-seq
MIRT2039783	hsa-miR-3190	CLIP-seq
MIRT2269604	hsa-miR-3193	CLIP-seq
MIRT2269605	hsa-miR-3201	CLIP-seq
MIRT2269606	hsa-miR-320a	CLIP-seq
MIRT2269607	hsa-miR-320b	CLIP-seq
MIRT2269608	hsa-miR-320c	CLIP-seq
MIRT2269609	hsa-miR-320d	CLIP-seq
MIRT2269610	hsa-miR-323-3p	CLIP-seq
MIRT2269611	hsa-miR-323-5p	CLIP-seq
MIRT2269612	hsa-miR-328	CLIP-seq
MIRT2269613	hsa-miR-330-3p	CLIP-seq
MIRT2039785	hsa-miR-335	CLIP-seq
MIRT2269614	hsa-miR-339-5p	CLIP-seq
MIRT2269615	hsa-miR-345	CLIP-seq
MIRT2039786	hsa-miR-3591-5p	CLIP-seq
MIRT1140283	hsa-miR-3611	CLIP-seq
MIRT2269616	hsa-miR-361-3p	CLIP-seq
MIRT2039787	hsa-miR-3617	CLIP-seq
MIRT2269617	hsa-miR-3619-3p	CLIP-seq
MIRT2039788	hsa-miR-3622a-3p	CLIP-seq
MIRT2039789	hsa-miR-3622b-3p	CLIP-seq
MIRT2269618	hsa-miR-362-5p	CLIP-seq
MIRT2269619	hsa-miR-3657	CLIP-seq
MIRT2269620	hsa-miR-3658	CLIP-seq
MIRT2039790	hsa-miR-3662	CLIP-seq
MIRT1140284	hsa-miR-3664-3p	CLIP-seq
MIRT2269621	hsa-miR-3665	CLIP-seq
MIRT2269622	hsa-miR-3679-3p	CLIP-seq
MIRT2269623	hsa-miR-3680	CLIP-seq
MIRT2269624	hsa-miR-3682-5p	CLIP-seq
MIRT2269625	hsa-miR-3689d	CLIP-seq
MIRT2269626	hsa-miR-3690	CLIP-seq
MIRT2269627	hsa-miR-3691-5p	CLIP-seq
MIRT2269628	hsa-miR-371-5p	CLIP-seq
MIRT2269629	hsa-miR-376a	CLIP-seq
MIRT2269630	hsa-miR-376b	CLIP-seq
MIRT1140286	hsa-miR-3913-3p	CLIP-seq
MIRT2269631	hsa-miR-3916	CLIP-seq
MIRT1140287	hsa-miR-3924	CLIP-seq
MIRT2039793	hsa-miR-3927	CLIP-seq
MIRT2269632	hsa-miR-3934	CLIP-seq
MIRT2269633	hsa-miR-3942-3p	CLIP-seq
MIRT2269634	hsa-miR-3943	CLIP-seq
MIRT2269635	hsa-miR-3973	CLIP-seq
MIRT1140289	hsa-miR-409-3p	CLIP-seq
MIRT2039794	hsa-miR-424	CLIP-seq
MIRT1140290	hsa-miR-4251	CLIP-seq
MIRT1140291	hsa-miR-4252	CLIP-seq
MIRT2269636	hsa-miR-4254	CLIP-seq
MIRT2269637	hsa-miR-4262	CLIP-seq
MIRT2269638	hsa-miR-4267	CLIP-seq
MIRT1140292	hsa-miR-4269	CLIP-seq
MIRT2269639	hsa-miR-4270	CLIP-seq
MIRT2269640	hsa-miR-4277	CLIP-seq
MIRT2039795	hsa-miR-4279	CLIP-seq
MIRT2039796	hsa-miR-4286	CLIP-seq
MIRT2039797	hsa-miR-4289	CLIP-seq
MIRT2269641	hsa-miR-4292	CLIP-seq
MIRT2269642	hsa-miR-4297	CLIP-seq
MIRT1140293	hsa-miR-4303	CLIP-seq
MIRT2269643	hsa-miR-4305	CLIP-seq
MIRT2269644	hsa-miR-4308	CLIP-seq
MIRT2039799	hsa-miR-4318	CLIP-seq
MIRT1140294	hsa-miR-4319	CLIP-seq
MIRT2039800	hsa-miR-4320	CLIP-seq
MIRT2269645	hsa-miR-4323	CLIP-seq
MIRT2269646	hsa-miR-4325	CLIP-seq
MIRT1140295	hsa-miR-4329	CLIP-seq
MIRT1140296	hsa-miR-433	CLIP-seq
MIRT1140297	hsa-miR-4418	CLIP-seq
MIRT2269647	hsa-miR-4419a	CLIP-seq
MIRT2269648	hsa-miR-4421	CLIP-seq
MIRT2269649	hsa-miR-4422	CLIP-seq
MIRT2269650	hsa-miR-4427	CLIP-seq
MIRT2269651	hsa-miR-4429	CLIP-seq
MIRT2269652	hsa-miR-4434	CLIP-seq
MIRT2269653	hsa-miR-4436b-5p	CLIP-seq
MIRT2269654	hsa-miR-4441	CLIP-seq
MIRT2269655	hsa-miR-4459	CLIP-seq
MIRT1140298	hsa-miR-4476	CLIP-seq
MIRT2269656	hsa-miR-4484	CLIP-seq
MIRT2269657	hsa-miR-4485	CLIP-seq
MIRT2269658	hsa-miR-4490	CLIP-seq
MIRT2269659	hsa-miR-4501	CLIP-seq
MIRT2039801	hsa-miR-4502	CLIP-seq
MIRT2269660	hsa-miR-4503	CLIP-seq
MIRT2269661	hsa-miR-4504	CLIP-seq
MIRT2269662	hsa-miR-4509	CLIP-seq
MIRT2269663	hsa-miR-4510	CLIP-seq
MIRT1140300	hsa-miR-4514	CLIP-seq
MIRT2269664	hsa-miR-4516	CLIP-seq
MIRT1140301	hsa-miR-4518	CLIP-seq
MIRT2269665	hsa-miR-452	CLIP-seq
MIRT2269666	hsa-miR-4522	CLIP-seq
MIRT2039802	hsa-miR-4530	CLIP-seq
MIRT2269667	hsa-miR-4633-5p	CLIP-seq
MIRT2269668	hsa-miR-4641	CLIP-seq
MIRT2269669	hsa-miR-4642	CLIP-seq
MIRT2269670	hsa-miR-4645-5p	CLIP-seq
MIRT2039803	hsa-miR-4646-3p	CLIP-seq
MIRT2039804	hsa-miR-4650-3p	CLIP-seq
MIRT2269671	hsa-miR-4652-3p	CLIP-seq
MIRT2039805	hsa-miR-4662a-3p	CLIP-seq
MIRT2269672	hsa-miR-4665-3p	CLIP-seq
MIRT2269673	hsa-miR-4673	CLIP-seq
MIRT2269674	hsa-miR-4674	CLIP-seq
MIRT2269675	hsa-miR-4676-3p	CLIP-seq
MIRT2269676	hsa-miR-4684-3p	CLIP-seq
MIRT1140302	hsa-miR-4692	CLIP-seq
MIRT2269677	hsa-miR-4693-5p	CLIP-seq
MIRT2269678	hsa-miR-4698	CLIP-seq
MIRT2269679	hsa-miR-4699-3p	CLIP-seq
MIRT2269680	hsa-miR-4704-3p	CLIP-seq
MIRT1140303	hsa-miR-4704-5p	CLIP-seq
MIRT2269681	hsa-miR-4707-5p	CLIP-seq
MIRT2269682	hsa-miR-4709-3p	CLIP-seq
MIRT2269683	hsa-miR-4711-5p	CLIP-seq
MIRT2269684	hsa-miR-4714-5p	CLIP-seq
MIRT2269685	hsa-miR-4726-3p	CLIP-seq
MIRT2039806	hsa-miR-4727-5p	CLIP-seq
MIRT2269686	hsa-miR-4728-3p	CLIP-seq
MIRT2269687	hsa-miR-4731-5p	CLIP-seq
MIRT1140304	hsa-miR-4732-3p	CLIP-seq
MIRT1140305	hsa-miR-4733-5p	CLIP-seq
MIRT2269688	hsa-miR-4735-5p	CLIP-seq
MIRT2269689	hsa-miR-4739	CLIP-seq
MIRT1140306	hsa-miR-4742-5p	CLIP-seq
MIRT2269690	hsa-miR-4744	CLIP-seq
MIRT2269691	hsa-miR-4751	CLIP-seq
MIRT2039807	hsa-miR-4752	CLIP-seq
MIRT2269692	hsa-miR-4753-5p	CLIP-seq
MIRT2269693	hsa-miR-4756-5p	CLIP-seq
MIRT1140307	hsa-miR-4760-3p	CLIP-seq
MIRT2269694	hsa-miR-4762-3p	CLIP-seq
MIRT1140308	hsa-miR-4763-3p	CLIP-seq
MIRT1140309	hsa-miR-4764-3p	CLIP-seq
MIRT1140310	hsa-miR-4766-5p	CLIP-seq
MIRT2269695	hsa-miR-4771	CLIP-seq
MIRT2269696	hsa-miR-4774-3p	CLIP-seq
MIRT2269697	hsa-miR-4774-5p	CLIP-seq
MIRT2269698	hsa-miR-4775	CLIP-seq
MIRT2269699	hsa-miR-4777-3p	CLIP-seq
MIRT2269700	hsa-miR-4778-3p	CLIP-seq
MIRT2039808	hsa-miR-4778-5p	CLIP-seq
MIRT2269701	hsa-miR-4779	CLIP-seq
MIRT2269702	hsa-miR-4782-5p	CLIP-seq
MIRT2269703	hsa-miR-4791	CLIP-seq
MIRT2269704	hsa-miR-4793-3p	CLIP-seq
MIRT2269705	hsa-miR-4796-3p	CLIP-seq
MIRT2269706	hsa-miR-483-3p	CLIP-seq
MIRT2269707	hsa-miR-485-5p	CLIP-seq
MIRT2269708	hsa-miR-486-5p	CLIP-seq
MIRT1140311	hsa-miR-488	CLIP-seq
MIRT1140312	hsa-miR-489	CLIP-seq
MIRT2269709	hsa-miR-490-3p	CLIP-seq
MIRT2269710	hsa-miR-494	CLIP-seq
MIRT2039809	hsa-miR-497	CLIP-seq
MIRT2039810	hsa-miR-498	CLIP-seq
MIRT1140313	hsa-miR-499-3p	CLIP-seq
MIRT2269711	hsa-miR-499-5p	CLIP-seq
MIRT1140314	hsa-miR-499a-3p	CLIP-seq
MIRT2269712	hsa-miR-499a-5p	CLIP-seq
MIRT2039811	hsa-miR-500a	CLIP-seq
MIRT2269713	hsa-miR-500b	CLIP-seq
MIRT1140315	hsa-miR-501-3p	CLIP-seq
MIRT2269714	hsa-miR-501-5p	CLIP-seq
MIRT1140316	hsa-miR-502-3p	CLIP-seq
MIRT2269715	hsa-miR-502-5p	CLIP-seq
MIRT1140317	hsa-miR-509-3-5p	CLIP-seq
MIRT1140318	hsa-miR-509-5p	CLIP-seq
MIRT2269716	hsa-miR-520d-5p	CLIP-seq
MIRT2269717	hsa-miR-520g	CLIP-seq
MIRT2269718	hsa-miR-520h	CLIP-seq
MIRT2269719	hsa-miR-524-5p	CLIP-seq
MIRT2269720	hsa-miR-532-5p	CLIP-seq
MIRT2269721	hsa-miR-539	CLIP-seq
MIRT2039812	hsa-miR-544	CLIP-seq
MIRT2269722	hsa-miR-548a-5p	CLIP-seq
MIRT2269723	hsa-miR-548ab	CLIP-seq
MIRT2269724	hsa-miR-548ac	CLIP-seq
MIRT2269725	hsa-miR-548ak	CLIP-seq
MIRT2269726	hsa-miR-548an	CLIP-seq
MIRT2269727	hsa-miR-548b-3p	CLIP-seq
MIRT2269728	hsa-miR-548b-5p	CLIP-seq
MIRT2269729	hsa-miR-548c-5p	CLIP-seq
MIRT2269730	hsa-miR-548d-3p	CLIP-seq
MIRT2269731	hsa-miR-548d-5p	CLIP-seq
MIRT2269732	hsa-miR-548h	CLIP-seq
MIRT2269733	hsa-miR-548i	CLIP-seq
MIRT2269734	hsa-miR-548j	CLIP-seq
MIRT2269735	hsa-miR-548l	CLIP-seq
MIRT2269736	hsa-miR-548o	CLIP-seq
MIRT2269737	hsa-miR-548t	CLIP-seq
MIRT1140321	hsa-miR-548v	CLIP-seq
MIRT2269738	hsa-miR-548w	CLIP-seq
MIRT2269739	hsa-miR-548y	CLIP-seq
MIRT2269740	hsa-miR-548z	CLIP-seq
MIRT2269741	hsa-miR-549	CLIP-seq
MIRT2269742	hsa-miR-559	CLIP-seq
MIRT2269743	hsa-miR-561	CLIP-seq
MIRT1140322	hsa-miR-570	CLIP-seq
MIRT2269744	hsa-miR-579	CLIP-seq
MIRT1140323	hsa-miR-580	CLIP-seq
MIRT2269745	hsa-miR-584	CLIP-seq
MIRT2269746	hsa-miR-587	CLIP-seq
MIRT2269747	hsa-miR-589	CLIP-seq
MIRT2269748	hsa-miR-590-3p	CLIP-seq
MIRT2269749	hsa-miR-591	CLIP-seq
MIRT2269750	hsa-miR-595	CLIP-seq
MIRT2039813	hsa-miR-597	CLIP-seq
MIRT2269751	hsa-miR-604	CLIP-seq
MIRT2269752	hsa-miR-613	CLIP-seq
MIRT2269753	hsa-miR-617	CLIP-seq
MIRT1140324	hsa-miR-618	CLIP-seq
MIRT2269754	hsa-miR-628-5p	CLIP-seq
MIRT2269755	hsa-miR-629	CLIP-seq
MIRT2269756	hsa-miR-633	CLIP-seq
MIRT2039814	hsa-miR-634	CLIP-seq
MIRT2269757	hsa-miR-635	CLIP-seq
MIRT2039815	hsa-miR-641	CLIP-seq
MIRT2269758	hsa-miR-642a	CLIP-seq
MIRT2269759	hsa-miR-642b	CLIP-seq
MIRT2269760	hsa-miR-647	CLIP-seq
MIRT2269761	hsa-miR-651	CLIP-seq
MIRT2039816	hsa-miR-653	CLIP-seq
MIRT2269762	hsa-miR-654-3p	CLIP-seq
MIRT2269763	hsa-miR-657	CLIP-seq
MIRT2269764	hsa-miR-668	CLIP-seq
MIRT1140326	hsa-miR-670	CLIP-seq
MIRT1140327	hsa-miR-676	CLIP-seq
MIRT2269765	hsa-miR-760	CLIP-seq
MIRT1140328	hsa-miR-873	CLIP-seq
MIRT2269766	hsa-miR-875-5p	CLIP-seq
MIRT2269767	hsa-miR-876-3p	CLIP-seq
MIRT2269768	hsa-miR-876-5p	CLIP-seq
MIRT2269769	hsa-miR-885-5p	CLIP-seq
MIRT2269770	hsa-miR-888	CLIP-seq
MIRT2269771	hsa-miR-892b	CLIP-seq
MIRT2039817	hsa-miR-922	CLIP-seq
MIRT1140329	hsa-miR-940	CLIP-seq
MIRT2269772	hsa-miR-96	CLIP-seq
MIRT2039766	hsa-miR-146a	CLIP-seq
MIRT2039767	hsa-miR-146b-5p	CLIP-seq
MIRT2039783	hsa-miR-3190	CLIP-seq
MIRT1140290	hsa-miR-4251	CLIP-seq
MIRT2039795	hsa-miR-4279	CLIP-seq
MIRT2039797	hsa-miR-4289	CLIP-seq
MIRT1140298	hsa-miR-4476	CLIP-seq
MIRT2269658	hsa-miR-4490	CLIP-seq
MIRT2269668	hsa-miR-4641	CLIP-seq
MIRT2390762	hsa-miR-4691-5p	CLIP-seq
MIRT1140303	hsa-miR-4704-5p	CLIP-seq
MIRT2039806	hsa-miR-4727-5p	CLIP-seq
MIRT2039807	hsa-miR-4752	CLIP-seq
MIRT1140310	hsa-miR-4766-5p	CLIP-seq
MIRT2039808	hsa-miR-4778-5p	CLIP-seq
MIRT2039811	hsa-miR-500a	CLIP-seq
MIRT1140323	hsa-miR-580	CLIP-seq
MIRT2269753	hsa-miR-617	CLIP-seq
MIRT1140327	hsa-miR-676	CLIP-seq
MIRT1140328	hsa-miR-873	CLIP-seq
MIRT2390763	hsa-miR-942	CLIP-seq
MIRT2269549	hsa-miR-1267	CLIP-seq
MIRT2269555	hsa-miR-132	CLIP-seq
MIRT2269580	hsa-miR-212	CLIP-seq
MIRT2269603	hsa-miR-3182	CLIP-seq
MIRT2269646	hsa-miR-4325	CLIP-seq
MIRT2269671	hsa-miR-4652-3p	CLIP-seq
MIRT2269676	hsa-miR-4684-3p	CLIP-seq
MIRT2269534	hsa-miR-1	CLIP-seq
MIRT2269536	hsa-miR-105	CLIP-seq
MIRT2269542	hsa-miR-1183	CLIP-seq
MIRT1140272	hsa-miR-125a-5p	CLIP-seq
MIRT1140273	hsa-miR-125b	CLIP-seq
MIRT2269551	hsa-miR-1272	CLIP-seq
MIRT2269557	hsa-miR-1322	CLIP-seq
MIRT2269564	hsa-miR-149	CLIP-seq
MIRT2039774	hsa-miR-1913	CLIP-seq
MIRT2039778	hsa-miR-205	CLIP-seq
MIRT2269577	hsa-miR-206	CLIP-seq
MIRT2269581	hsa-miR-224	CLIP-seq
MIRT2039781	hsa-miR-298	CLIP-seq
MIRT1140281	hsa-miR-3119	CLIP-seq
MIRT2269589	hsa-miR-3140-3p	CLIP-seq
MIRT2269591	hsa-miR-3145-3p	CLIP-seq
MIRT2269592	hsa-miR-3145-5p	CLIP-seq
MIRT1140282	hsa-miR-3158-3p	CLIP-seq
MIRT2269595	hsa-miR-3158-5p	CLIP-seq
MIRT2269606	hsa-miR-320a	CLIP-seq
MIRT2269607	hsa-miR-320b	CLIP-seq
MIRT2269608	hsa-miR-320c	CLIP-seq
MIRT2269609	hsa-miR-320d	CLIP-seq
MIRT2269610	hsa-miR-323-3p	CLIP-seq
MIRT2039784	hsa-miR-324-3p	CLIP-seq
MIRT2039788	hsa-miR-3622a-3p	CLIP-seq
MIRT2039789	hsa-miR-3622b-3p	CLIP-seq
MIRT2039790	hsa-miR-3662	CLIP-seq
MIRT2269623	hsa-miR-3680	CLIP-seq
MIRT2269627	hsa-miR-3691-5p	CLIP-seq
MIRT2269628	hsa-miR-371-5p	CLIP-seq
MIRT1140286	hsa-miR-3913-3p	CLIP-seq
MIRT1140290	hsa-miR-4251	CLIP-seq
MIRT1140293	hsa-miR-4303	CLIP-seq
MIRT2039799	hsa-miR-4318	CLIP-seq
MIRT1140294	hsa-miR-4319	CLIP-seq
MIRT2269646	hsa-miR-4325	CLIP-seq
MIRT1140295	hsa-miR-4329	CLIP-seq
MIRT1140296	hsa-miR-433	CLIP-seq
MIRT2269650	hsa-miR-4427	CLIP-seq
MIRT2269651	hsa-miR-4429	CLIP-seq
MIRT2269653	hsa-miR-4436b-5p	CLIP-seq
MIRT2269668	hsa-miR-4641	CLIP-seq
MIRT2269678	hsa-miR-4698	CLIP-seq
MIRT2269683	hsa-miR-4711-5p	CLIP-seq
MIRT2039806	hsa-miR-4727-5p	CLIP-seq
MIRT1140304	hsa-miR-4732-3p	CLIP-seq
MIRT2039807	hsa-miR-4752	CLIP-seq
MIRT1140307	hsa-miR-4760-3p	CLIP-seq
MIRT2269694	hsa-miR-4762-3p	CLIP-seq
MIRT1140310	hsa-miR-4766-5p	CLIP-seq
MIRT2269698	hsa-miR-4775	CLIP-seq
MIRT2269699	hsa-miR-4777-3p	CLIP-seq
MIRT2269700	hsa-miR-4778-3p	CLIP-seq
MIRT2269704	hsa-miR-4793-3p	CLIP-seq
MIRT2269706	hsa-miR-483-3p	CLIP-seq
MIRT1140311	hsa-miR-488	CLIP-seq
MIRT1140312	hsa-miR-489	CLIP-seq
MIRT2039812	hsa-miR-544	CLIP-seq
MIRT2269741	hsa-miR-549	CLIP-seq
MIRT2269744	hsa-miR-579	CLIP-seq
MIRT1140323	hsa-miR-580	CLIP-seq
MIRT2269746	hsa-miR-587	CLIP-seq
MIRT2269748	hsa-miR-590-3p	CLIP-seq
MIRT2269750	hsa-miR-595	CLIP-seq
MIRT2269752	hsa-miR-613	CLIP-seq
MIRT2568850	hsa-miR-645	CLIP-seq
MIRT2269764	hsa-miR-668	CLIP-seq
MIRT1140326	hsa-miR-670	CLIP-seq
MIRT2269770	hsa-miR-888	CLIP-seq
MIRT2269771	hsa-miR-892b	CLIP-seq
MIRT2269536	hsa-miR-105	CLIP-seq
MIRT2269542	hsa-miR-1183	CLIP-seq
MIRT1140272	hsa-miR-125a-5p	CLIP-seq
MIRT1140273	hsa-miR-125b	CLIP-seq
MIRT2269564	hsa-miR-149	CLIP-seq
MIRT2039778	hsa-miR-205	CLIP-seq
MIRT1140278	hsa-miR-221	CLIP-seq
MIRT1140279	hsa-miR-222	CLIP-seq
MIRT2269591	hsa-miR-3145-3p	CLIP-seq
MIRT1140282	hsa-miR-3158-3p	CLIP-seq
MIRT2269610	hsa-miR-323-3p	CLIP-seq
MIRT2269623	hsa-miR-3680	CLIP-seq
MIRT2269627	hsa-miR-3691-5p	CLIP-seq
MIRT2269628	hsa-miR-371-5p	CLIP-seq
MIRT1140285	hsa-miR-376c	CLIP-seq
MIRT1140286	hsa-miR-3913-3p	CLIP-seq
MIRT1140288	hsa-miR-3940-5p	CLIP-seq
MIRT1140290	hsa-miR-4251	CLIP-seq
MIRT1140293	hsa-miR-4303	CLIP-seq
MIRT2039799	hsa-miR-4318	CLIP-seq
MIRT1140294	hsa-miR-4319	CLIP-seq
MIRT2269646	hsa-miR-4325	CLIP-seq
MIRT1140295	hsa-miR-4329	CLIP-seq
MIRT1140296	hsa-miR-433	CLIP-seq
MIRT1140299	hsa-miR-4507	CLIP-seq
MIRT2684786	hsa-miR-451b	CLIP-seq
MIRT1140304	hsa-miR-4732-3p	CLIP-seq
MIRT2039807	hsa-miR-4752	CLIP-seq
MIRT1140307	hsa-miR-4760-3p	CLIP-seq
MIRT1140310	hsa-miR-4766-5p	CLIP-seq
MIRT2269698	hsa-miR-4775	CLIP-seq
MIRT2269699	hsa-miR-4777-3p	CLIP-seq
MIRT2269704	hsa-miR-4793-3p	CLIP-seq
MIRT1140311	hsa-miR-488	CLIP-seq
MIRT1140312	hsa-miR-489	CLIP-seq
MIRT1140319	hsa-miR-515-5p	CLIP-seq
MIRT1140321	hsa-miR-548v	CLIP-seq
MIRT2269741	hsa-miR-549	CLIP-seq
MIRT1140323	hsa-miR-580	CLIP-seq
MIRT2269750	hsa-miR-595	CLIP-seq
MIRT1140326	hsa-miR-670	CLIP-seq
MIRT2269771	hsa-miR-892b	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
AR	Unknown	17483314

Show/Hide all(97)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	ISS
GO:0000151	Component	Ubiquitin ligase complex	IEA
GO:0000785	Component	Chromatin	IEA
GO:0000902	Process	Cell morphogenesis	IMP	17223341
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0001525	Process	Angiogenesis	ISS
GO:0001889	Process	Liver development	IEA
GO:0001892	Process	Embryonic placenta development	IEA
GO:0002088	Process	Lens development in camera-type eye	ISS
GO:0002154	Process	Thyroid hormone mediated signaling pathway	IMP	16314496
GO:0003222	Process	Ventricular trabecula myocardium morphogenesis	IEA
GO:0003406	Process	Retinal pigment epithelium development	IEA
GO:0003682	Function	Chromatin binding	IMP	17641689
GO:0003712	Function	Transcription coregulator activity	IBA	21873635
GO:0003712	Function	Transcription coregulator activity	IDA	10198638
GO:0003713	Function	Transcription coactivator activity	IDA	9653119, 12037571, 12218053, 16314496, 19497978
GO:0003713	Function	Transcription coactivator activity	IMP	17223341, 24245781
GO:0003714	Function	Transcription corepressor activity	ISS
GO:0005515	Function	Protein binding	IPI	9653119, 12403843, 17132730, 17254542, 17641689, 18391015, 19786558, 21478865, 24245781, 24882805, 24981860, 25303530, 28514442, 29997176, 31527615
GO:0005634	Component	Nucleus	IDA	10235267, 16314496, 17223341, 17827210, 19497978
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	16314496
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0006367	Process	Transcription initiation from RNA polymerase II promoter	TAS
GO:0006590	Process	Thyroid hormone generation	IEA
GO:0006606	Process	Protein import into nucleus	IEA
GO:0006702	Process	Androgen biosynthetic process	IMP	19497978
GO:0007420	Process	Brain development	IEA
GO:0007595	Process	Lactation	IEA
GO:0008134	Function	Transcription factor binding	IPI	17641689, 19497978
GO:0010628	Process	Positive regulation of gene expression	IDA	17827210
GO:0010628	Process	Positive regulation of gene expression	IMP	17223341
GO:0010839	Process	Negative regulation of keratinocyte proliferation	IMP	17223341
GO:0016020	Component	Membrane	HDA	19946888
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016592	Component	Mediator complex	IBA	21873635
GO:0016592	Component	Mediator complex	IDA	10198638, 12037571, 14638676
GO:0016592	Component	Mediator complex	IMP	17641689
GO:0016922	Function	Nuclear receptor binding	IDA	18391015
GO:0016922	Function	Nuclear receptor binding	IPI	9653119
GO:0019216	Process	Regulation of lipid metabolic process	TAS
GO:0030216	Process	Keratinocyte differentiation	IMP	17223341
GO:0030224	Process	Monocyte differentiation	IEA
GO:0030331	Function	Estrogen receptor binding	IPI	9653119
GO:0030374	Function	Nuclear receptor coactivator activity	IMP	17641689, 18391015
GO:0030374	Function	Nuclear receptor coactivator activity	NAS	10235266
GO:0030518	Process	Intracellular steroid hormone receptor signaling pathway	IDA	11867769
GO:0031100	Process	Animal organ regeneration	IEA
GO:0031490	Function	Chromatin DNA binding	IEA
GO:0032993	Component	Protein-DNA complex	IEA
GO:0033148	Process	Positive regulation of intracellular estrogen receptor signaling pathway	IEA
GO:0035050	Process	Embryonic heart tube development	IEA
GO:0035116	Process	Embryonic hindlimb morphogenesis	IEA
GO:0035162	Process	Embryonic hemopoiesis	IEA
GO:0035257	Function	Nuclear hormone receptor binding	IPI	10478845
GO:0035357	Process	Peroxisome proliferator activated receptor signaling pathway	IEA
GO:0035729	Process	Cellular response to hepatocyte growth factor stimulus	IEA
GO:0035855	Process	Megakaryocyte development	ISS
GO:0042789	Process	MRNA transcription by RNA polymerase II	ISS
GO:0042809	Function	Vitamin D receptor binding	IBA	21873635
GO:0042809	Function	Vitamin D receptor binding	IPI	9653119
GO:0042809	Function	Vitamin D receptor binding	NAS	10235266
GO:0042809	Function	Vitamin D receptor binding	TAS	17223341
GO:0042974	Function	Retinoic acid receptor binding	IBA	21873635
GO:0042974	Function	Retinoic acid receptor binding	IPI	9653119
GO:0042975	Function	Peroxisome proliferator activated receptor binding	IPI	9653119
GO:0043066	Process	Negative regulation of apoptotic process	ISS
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0045444	Process	Fat cell differentiation	IDA	12037571
GO:0045618	Process	Positive regulation of keratinocyte differentiation	IMP	17082781
GO:0045648	Process	Positive regulation of erythrocyte differentiation	IMP	24245781
GO:0045665	Process	Negative regulation of neuron differentiation	ISS
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	10198638, 16314496
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	9653119, 12037571, 17827210, 18391015, 19497978
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	17082781, 17641689
GO:0046966	Function	Thyroid hormone receptor binding	IBA	21873635
GO:0046966	Function	Thyroid hormone receptor binding	IDA	10198638
GO:0046966	Function	Thyroid hormone receptor binding	IPI	9653119
GO:0048821	Process	Erythrocyte development	ISS
GO:0048822	Process	Enucleate erythrocyte development	IEA
GO:0050693	Function	LBD domain binding	IPI	17827210
GO:0060261	Process	Positive regulation of transcription initiation from RNA polymerase II promoter	IDA	12218053, 16314496
GO:0060335	Process	Positive regulation of interferon-gamma-mediated signaling pathway	IEA
GO:0060744	Process	Mammary gland branching involved in thelarche	IEA
GO:0060745	Process	Mammary gland branching involved in pregnancy	IEA
GO:0060750	Process	Epithelial cell proliferation involved in mammary gland duct elongation	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070318	Process	Positive regulation of G0 to G1 transition	IEA
GO:0070562	Process	Regulation of vitamin D receptor signaling pathway	IEA
GO:0071364	Process	Cellular response to epidermal growth factor stimulus	IDA	16314496
GO:0071383	Process	Cellular response to steroid hormone stimulus	IDA	18391015
GO:0097067	Process	Cellular response to thyroid hormone stimulus	IBA	21873635
GO:0097067	Process	Cellular response to thyroid hormone stimulus	IDA	18391015
GO:1990841	Function	Promoter-specific chromatin binding	IEA
GO:2000347	Process	Positive regulation of hepatocyte proliferation	IEA
GO:2001141	Process	Regulation of RNA biosynthetic process	IMP	17223341

MIM	HGNC	e!Ensembl
604311	9234	ENSG00000125686

Protein

UniProt ID

Q15648

Protein name

Mediator of RNA polymerase II transcription subunit 1 (Activator-recruited cofactor 205 kDa component) (ARC205) (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone recepto

Protein function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RN

PDB

1RJK , 1RK3 , 1RKG , 1RKH , 2O4J , 2O4R , 2ZFX , 3A2H , 3AUN , 3VJS , 3VJT , 3VRT , 3VRU , 3VRV , 3VRW , 3W0G , 3W0H , 3W0I , 3W0J , 3W5P , 3W5Q , 3W5R , 3W5T , 3WT5 , 3WT6 , 3WT7 , 3WTQ , 4YNK , 5AWJ , 5AWK , 5B41 , 5B5B , 5GIC , 5GID , 5GIE , 5XPM , 5XPN , 5XPO , 5XPP , 5XUQ , 5XZF , 5XZH , 5ZWE , 5ZWF , 5ZWH , 5ZWI , 6D94 , 6JEZ , 6K5O , 6ONJ , 7C7V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10744	Med1	59 → 426	Mediator of RNA polymerase II transcription subunit 1	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:9444950, ECO:0000269|PubMed:9653119}.

Sequence

MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVS
CLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQL
CDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPI
ILHENNVSRSLGMNASVTIEGTSAVYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLP
ACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHN
MRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTL
IGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLY
KGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNL
PPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQ
NPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTL
YGSSPLERQNSSSGSPRMEICSGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ
NPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVT
DILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPAD
LIADAAGSPSSDSPTNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFAS
QALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTT
GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK
SPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSH
SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGS
SQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG
GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP
PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPG
GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE
SKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGST
PKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKH
KKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRL
SPDFMIGEEDDDLMDVALIGN

Sequence length

1581

Interactions

View interactions

	KEGG		Reactome
	Endocrine resistance Thyroid hormone signaling pathway		RORA activates gene expression PPARA activates gene expression Generic Transcription Pathway Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Nuclear Receptor transcription pathway Regulation of lipid metabolism by PPARalpha Circadian Clock Estrogen-dependent gene expression

Show/Hide Unknown Diseases (3)

Disease term	Disease name	References	Source
Unknown
Asthma	Asthma	31619474	ClinVar, GWAS
Endometriosis	Endometriosis	22138541	ClinVar
Systemic lupus erythematosus	Systemic lupus erythematosus		GWAS

Show/Hide Text Mining Associations (30)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Stimulate	16601283
Adenocarcinoma of Lung	Stimulate	16601283
Atrial Fibrillation	Associate	40113094
Bipolar Disorder	Associate	28291257
Breast Neoplasms	Associate	10485914, 15989967, 19183483, 20160030, 21288332, 22345290, 22964581, 27506935, 27966906, 30087366
Carcinogenesis	Associate	35131256
Carcinoma Hepatocellular	Associate	35069777
Carcinoma Ovarian Epithelial	Associate	37525498
Carcinoma Pancreatic Ductal	Associate	36302831
Colorectal Neoplasms	Associate	19127118, 26130665
Ectrodactyly cardiopathy dysmorphism	Associate	40113094
Leukemia	Associate	33542097
Leukemia Myeloid Acute	Associate	20501850
Liver Failure Acute	Associate	34612778
Lupus Erythematosus Systemic	Associate	24871463
Lymphatic Metastasis	Associate	26130665
Melanoma	Associate	31695025
Melanoma Cutaneous Malignant	Associate	35131256
Muscular Atrophy	Stimulate	35800215
Neoplasm Metastasis	Associate	26130665, 35131256
Neoplasms	Inhibit	17229543, 26461474, 31695025
Neoplasms	Associate	26910888
Ovarian Diseases	Associate	37525498
Ovarian Neoplasms	Inhibit	19127118
Ovarian Neoplasms	Associate	37525498
Pancreatic Neoplasms	Associate	32367578
Prostatic Neoplasms	Associate	25481872, 31501863, 36535377
Prostatic Neoplasms Castration Resistant	Associate	21556051, 25481872
Stomach Neoplasms	Associate	17229543, 37800836
Thyroid Hormone Resistance Syndrome	Associate	36191835

MED1 (mediator complex subunit 1)