UGT1A1 (UDP glucuronosyltransferase family 1 member A1)

Gene

• Entrez ID: 54658
• Gene name: UDP glucuronosyltransferase family 1 member A1
• Gene symbol: UGT1A1
• Synonyms (NCBI Gene): BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT 1-1, UGT1, UGT1A
• Chromosome: 2
• Chromosome location: 2q37.1
• Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a comp

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1473325	hsa-miR-1202	CLIP-seq
MIRT1473326	hsa-miR-136	CLIP-seq
MIRT1473327	hsa-miR-3120-5p	CLIP-seq
MIRT1473328	hsa-miR-3130-3p	CLIP-seq
MIRT1473329	hsa-miR-3194-5p	CLIP-seq
MIRT1473330	hsa-miR-346	CLIP-seq
MIRT1473331	hsa-miR-3909	CLIP-seq
MIRT1473332	hsa-miR-3940-5p	CLIP-seq
MIRT1473333	hsa-miR-3972	CLIP-seq
MIRT1473334	hsa-miR-4288	CLIP-seq
MIRT1473335	hsa-miR-4421	CLIP-seq
MIRT1473336	hsa-miR-4507	CLIP-seq
MIRT1473337	hsa-miR-4766-5p	CLIP-seq
MIRT1473338	hsa-miR-4793-3p	CLIP-seq
MIRT1473339	hsa-miR-489	CLIP-seq
MIRT1473340	hsa-miR-514	CLIP-seq
MIRT1473341	hsa-miR-514b-3p	CLIP-seq
MIRT1473342	hsa-miR-548a-5p	CLIP-seq
MIRT1473343	hsa-miR-548ab	CLIP-seq
MIRT1473344	hsa-miR-548ak	CLIP-seq
MIRT1473345	hsa-miR-548b-5p	CLIP-seq
MIRT1473346	hsa-miR-548c-5p	CLIP-seq
MIRT1473347	hsa-miR-548d-5p	CLIP-seq
MIRT1473348	hsa-miR-548h	CLIP-seq
MIRT1473349	hsa-miR-548i	CLIP-seq
MIRT1473350	hsa-miR-548j	CLIP-seq
MIRT1473351	hsa-miR-548n	CLIP-seq
MIRT1473352	hsa-miR-548w	CLIP-seq
MIRT1473353	hsa-miR-548y	CLIP-seq
MIRT1473354	hsa-miR-559	CLIP-seq
MIRT1473355	hsa-miR-629	CLIP-seq
MIRT1473356	hsa-miR-632	CLIP-seq
MIRT2142600	hsa-miR-579	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
AHR	Activation	18172616
HNF1A	Activation	18172616
NR1I2	Activation	18172616
NR1I3	Activation	18172616
NR1I3	Unknown	11343253
NR3C1	Activation	18172616
NR3C1	Unknown	15557560

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001889	Process	Liver development	IEA
GO:0001972	Function	Retinoic acid binding	IDA	20308471
GO:0004857	Function	Enzyme inhibitor activity	IDA	19996319
GO:0005496	Function	Steroid binding	IDA	19996319
GO:0005783	Component	Endoplasmic reticulum	IDA	17179145
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IEA
GO:0006789	Process	Bilirubin conjugation	TAS
GO:0006953	Process	Acute-phase response	IEA
GO:0007584	Process	Response to nutrient	IEA
GO:0008202	Process	Steroid metabolic process	IC	19996319
GO:0008210	Process	Estrogen metabolic process	IDA	15472229, 18719240, 19830808
GO:0015020	Function	Glucuronosyltransferase activity	IDA	1898728, 15472229, 17179145, 18052087, 18719240, 19830808, 19996319, 20056724, 20308471, 22579593
GO:0017144	Process	Drug metabolic process	IC	19996319
GO:0019899	Function	Enzyme binding	IPI	17179145
GO:0031100	Process	Animal organ regeneration	IEA
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0034663	Component	Endoplasmic reticulum chaperone complex	IEA
GO:0042167	Process	Heme catabolic process	TAS
GO:0042493	Process	Response to drug	IEA
GO:0042573	Process	Retinoic acid metabolic process	IC	20308471
GO:0042594	Process	Response to starvation	IEA
GO:0042803	Function	Protein homodimerization activity	IDA	17179145
GO:0043086	Process	Negative regulation of catalytic activity	IEA
GO:0045939	Process	Negative regulation of steroid metabolic process	IC	19996319
GO:0046483	Process	Heterocycle metabolic process	IC	19996319
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0051552	Process	Flavone metabolic process	IDA	18052087
GO:0052695	Process	Cellular glucuronidation	IDA	15472229, 17179145, 18719240, 19830808, 22579593
GO:0052695	Process	Cellular glucuronidation	TAS
GO:0052696	Process	Flavonoid glucuronidation	IBA	21873635
GO:0052696	Process	Flavonoid glucuronidation	IDA	20056724
GO:0052697	Process	Xenobiotic glucuronidation	IBA	21873635
GO:0052697	Process	Xenobiotic glucuronidation	IDA	15472229, 18719240, 19830808, 20056724
GO:0070069	Component	Cytochrome complex	IEA
GO:0070980	Process	Biphenyl catabolic process	IEA
GO:0071361	Process	Cellular response to ethanol	IEA
GO:0071385	Process	Cellular response to glucocorticoid stimulus	IEA
GO:0071392	Process	Cellular response to estradiol stimulus	IEA

Other IDs

• MIM: 191740
• HGNC: 12530
• e!Ensembl: ENSG00000241635

Protein

• UniProt ID: P22309
• Protein name: UDP-glucuronosyltransferase 1A1 (UGT1A1) (EC 2.4.1.17) (Bilirubin-specific UDPGT isozyme 1) (hUG-BR1) (UDP-glucuronosyltransferase 1-1) (UDPGT 1-1) (UGT1*1) (UGT1-01) (UGT1.1) (UDP-glucuronosyltransferase 1A isoform 1)
• Protein function: [Isoform 1]: UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion i
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00201	UDPGT	28 → 524	UDP-glucoronosyl and UDP-glucosyl transferase	Family

• Tissue specificity: TISSUE SPECIFICITY: [Isoform 1]: Expressed in liver, colon and small intestine. Not expressed in kidney, esophagus and skin. {ECO:0000269|PubMed:1339448, ECO:0000269|PubMed:17187418, ECO:0000269|PubMed:18004212}.; TISSUE SPECIFICITY: [Isoform 2]: Expresse
• Sequence:

  MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVL
  APDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDS
  AMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLE
  FEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQR
  EVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEH
  GIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDL
  LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS
  EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHD
  LTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH

• Sequence length: 533

Pathways

KEGG:

Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Retinol metabolism
Porphyrin metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Biosynthesis of cofactors
Bile secretion
Chemical carcinogenesis - DNA adducts
Chemical carcinogenesis - receptor activation

Reactome:

Glucuronidation
Defective UGT1A1 causes hyperbilirubinemia

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Cerebral palsy	Cerebral Palsy	rs121918149, rs75184679, rs730880264, rs587777428, rs797045067, rs767399782, rs564185858, rs886039513
Crigler-najjar syndrome	Crigler Najjar syndrome, type 1, Crigler Najjar syndrome, type 2, Crigler-Najjar syndrome type 1, Crigler-Najjar syndrome type 2	rs587776761, rs72551353, rs111033539, rs72551349, rs72551348, rs587776762, rs62625011, rs281865418, rs587776763, rs587776764, rs587776765, rs587776766, rs34993780, rs72551351, rs111033541, rs797046091, rs748219743, rs72551340, rs1553620849, rs766536479, rs72551343, rs139607673	15712364, 7989595, 23992562, 24816252, 7989045, 11182932, 9039987, 11013440, 7906695, 1634050, 26697581, 17229650, 25370011, 9295054, 19830808, 8226884, 9497253, 8276413, 12402338, 8706880, 11370628, 18004206, 23099197, 17098698, 14550264, 16456422, 9639672, 8280139, 9621515
Dermatitis	Contact Dermatitis	rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174	25724174
Epileptic encephalopathy	Encephalopathies	rs587776508, rs121918334, rs121918317, rs121918321, rs74315390, rs28939684, rs74315391, rs74315392, rs118192244, rs121918622, rs121918623, rs121917953, rs121917955, rs121918624, rs121918625, rs121918626, rs121918629, rs121918632, rs118192218, rs118192219, rs118192222, rs118192226, rs118192228, rs118192234, rs118192236, rs118192235, rs118192242, rs118192185, rs118192188, rs118192246, rs118192186, rs118192194, rs118192199, rs118192201, rs118192202, rs118192203, rs118192204, rs118192205, rs118192206, rs118192208, rs118192215, rs118192216, rs118192239, rs397514458, rs387906686, rs202151337, rs121917957, rs121917929, rs121917927, rs121917966, rs121917941, rs121917964, rs121917943, rs121917965, rs121917918, rs121917963, rs121917911, rs121917912, rs121917986, rs121917987, rs121917913, rs121917945, rs121917996, rs121917975, rs121917919, rs121917993, rs121917915, rs121917995, rs121917976, rs121917994, rs121917926, rs121917951, rs121917952, rs121917980, rs121917921, rs121917935, rs121917936, rs121917984, rs121917937, rs121917985, rs121917938, rs121917928, rs121918753, rs121918781, rs121918782, rs121918784, rs121918734, rs121918788, rs121917969, rs121918775, rs121918786, rs121918796, rs121918745, rs121918740, rs121918741, rs121918789, rs121918742, rs121918791, rs121918811, rs121917922, rs121918744, rs121918778, rs121918767, rs121918779, rs121918770, rs121918783, rs121918773, rs121918793, rs267606051, rs398123585, rs398123588, rs398123593, rs587777164, rs587777219, rs587777310, rs587780446, rs587777492, rs587777495, rs587777577, rs267608501, rs587777721, rs587783192, rs587783200, rs104894745, rs587784453, rs587784454, rs587784438, rs587784440, rs727504136, rs727503974, rs727504140, rs727504173, rs201497300, rs786204967, rs794726739, rs794726845, rs779614747, rs794726726, rs794726763, rs794726754, rs794726760, rs794726759, rs199727342, rs794726800, rs794726752, rs794726825, rs794726809, rs794726696, rs794726699, rs794726705, rs794726784, rs794726779, rs794726821, rs146878122, rs794726816, rs794726744, rs794726854, rs794726710, rs794726733, rs542420576, rs794726772, rs794726842, rs794726718, rs794726761, rs794726697, rs794726775, rs397514459, rs767045134, rs794726766, rs794726742, rs794726730, rs794726778, rs794726736, rs794726773, rs794726790, rs794726826, rs794726753, rs794726799, rs794726844, rs794726782, rs794726798, rs794726824, rs794726827, rs794726803, rs794726711, rs794726762, rs786205598, rs863223345, rs794727128, rs794727337, rs794727361, rs794727444, rs794727740, rs794727792, rs794727970, rs863225068, rs796053181, rs796053130, rs796053048, rs796053086, rs796053103, rs796053043, rs796053085, rs796053035, rs796053031, rs796053029, rs796053022, rs139300715, rs796053014, rs1553522472, rs796053010, rs121917908, rs796053008, rs794726789, rs796053004, rs796053072, rs796052995, rs796053067, rs796052990, rs796052987, rs796052985, rs796053065, rs1553543316, rs796053064, rs796052977, rs796052976, rs796052973, rs796052972, rs781746113, rs796052960, rs796052959, rs796053054, rs1553551312, rs796052953, rs758871507, rs796053350, rs1554776228, rs796053352, rs796053390, rs796053353, rs796053359, rs796053361, rs796053366, rs796053367, rs796053370, rs796053368, rs796053373, rs796053376, rs796053377, rs1554768992, rs796053335, rs796053233, rs796053214, rs796053216, rs796053224, rs796053228, rs796053229, rs796052658, rs796052670, rs796052654, rs796052653, rs796052652, rs773171451, rs1555853593, rs759584387, rs796052650, rs118192233, rs796052657, rs796052644, rs796052645, rs796052641, rs796052640, rs775918190, rs796052636, rs796052626, rs796052623, rs796052621, rs796052620, rs796052618, rs796052617, rs796052663, rs797044983, rs797045013, rs797044878, rs797044951, rs797044873, rs797044938, rs797045969, rs118192212, rs863225037, rs863225036, rs863225030, rs863225031, rs864321707, rs864321712, rs869312684, rs869312920, rs869312939, rs878853250, rs878854263, rs878854262, rs751170778, rs878854974, rs878855236, rs1555794286, rs879255652, rs879255695, rs879255697, rs879255704, rs879255705, rs879255709, rs879255710, rs886039323, rs886039435, rs886039494, rs886039903, rs1135401734, rs1135401733, rs1135401732, rs886042004, rs886041716, rs886041961, rs886041668, rs886041246, rs886041339, rs886041766, rs886041262, rs886041715, rs886042528, rs886042605, rs886063501, rs1555850151, rs1057516123, rs1555853971, rs1057516115, rs1057516106, rs1057516105, rs1057516099, rs1057516098, rs1057516094, rs1057516089, rs1057516086, rs1057516085, rs1057516080, rs1057516079, rs1057516076, rs1057518325, rs1057517862, rs1057517849, rs1057518243, rs1057518258, rs1057517958, rs121917974, rs1057517959, rs796053374, rs1057517919, rs1057518489, rs1057518801, rs1057518816, rs759766243, rs1057518795, rs1057518985, rs1057519000, rs1057519269, rs1057519270, rs1057519452, rs375659415, rs1057519501, rs1057519528, rs1057519526, rs1057519527, rs1057519524, rs796053083, rs1057519529, rs1057519531, rs1057519547, rs1057519548, rs1057519545, rs1057519538, rs1057519539, rs1057519537, rs1057519540, rs1057519549, rs1057519550, rs1057519535, rs1057519536, rs1057519542, rs778291283, rs1057520486, rs794726765, rs750209664, rs121917753, rs1057521746, rs1057523858, rs1057520753, rs1057520413, rs1057521080, rs1057524599, rs778481061, rs768633670, rs796052655, rs1060502190, rs1060502183, rs121918780, rs1060502185, rs1057521537, rs1060502187, rs121918765, rs1060502182, rs121917981, rs1060502188, rs1060502189, rs1060503108, rs1060501724, rs1060501722, rs1060501723, rs1060501012, rs1060504137, rs1060500603, rs1060500602, rs1060499592, rs796053138, rs1064795579, rs1553520298, rs121918805, rs1064795733, rs1064796177, rs1064795735, rs1064794634, rs1064796384, rs1064796213, rs1064793923, rs1064794727, rs1064794533, rs1064795384, rs1555850842, rs1064794001, rs1064796151, rs1064795435, rs1064797284, rs1085307930, rs1085307730, rs1085307916, rs1085307876, rs1085307920, rs1131691773, rs1131691774, rs1131691675, rs1131691775, rs1131691693, rs1131691465, rs1131691830, rs1131691936, rs1057523728, rs1199412903, rs1555228303, rs1555507477, rs1554965669, rs1555499800, rs1553923787, rs922847767, rs368609628, rs1553286282, rs1266877537, rs794726749, rs1553551425, rs1553552390, rs1554778657, rs1555889130, rs1555881741, rs1553520320, rs1553522517, rs796053006, rs1553534296, rs1553541028, rs1553544579, rs1553551385, rs1553520380, rs1553525210, rs1553541473, rs761333438, rs1553520982, rs1553522321, rs1553520318, rs1553540503, rs1553540389, rs1553542199, rs1553543215, rs1553541172, rs1553549483, rs750901301, rs794726743, rs1553545660, rs1553561023, rs1553548096, rs1553552319, rs1553560760, rs1554037381, rs1554776948, rs1554778417, rs1057522982, rs1555219147, rs1555218657, rs1555850590, rs1555869758, rs1555873823, rs1553525325, rs794727813, rs1555228771, rs1553520530, rs1555870346, rs1555955296, rs1553551493, rs1555546796, rs1555870554, rs1555871832, rs77216276, rs1554689320, rs1554777496, rs1555881809, rs1553529461, rs12131800, rs1553517274, rs1555889127, rs1555951141, rs1553590192, rs1553531178, rs1555870470, rs927722314, rs1553523142, rs1041924436, rs1553544559, rs1553544821, rs1553520319, rs1553560677, rs1553521567, rs1553522331, rs1553519872, rs1553529426, rs1553519902, rs1553520029, rs1553545522, rs1553520439, rs146515561, rs1553549461, rs1553549834, rs1553546789, rs1553553614, rs1553560676, rs1553520227, rs1553524865, rs1553525036, rs1553560740, rs1553561016, rs1193718145, rs1554769099, rs936639741, rs1352024223, rs758779535, rs1555870506, rs747376305, rs1555869700, rs1555873656, rs1555873981, rs536000212, rs959316981, rs1554777470, rs1555889108, rs1559144583, rs1569219844, rs1564346538, rs1562159088, rs1559101839, rs1559114303, rs1559140110, rs1559140306, rs1043031572, rs121918756, rs1559199628, rs1559200672, rs796053095, rs1559210063, rs1559225495, rs1553549471, rs1559103294, rs1559105368, rs121918764, rs1559114837, rs1559122124, rs1559127505, rs1559128532, rs1559140855, rs1559149128, rs1559217391, rs1559220874, rs794726695, rs1559249734, rs1553553527, rs1559101585, rs1559110846, rs1559193050, rs1559216338, rs1559231284, rs148442069, rs1559105301, rs1559114202, rs121917954, rs1559195296, rs1553546763, rs1559238432, rs1559884460, rs1559887808, rs1564352002, rs1564349850, rs1564351103, rs1565933795, rs1565886685, rs1555228668, rs587777723, rs1564333757, rs375363057, rs1568932480, rs1568925719, rs770187706, rs1568864658, rs1568899375, rs118192209, rs1568932462, rs1568927747, rs1057518555, rs1559119345, rs1085307520, rs1559200901, rs970867558, rs1568940442, rs775162839, rs1568986619, rs1558308998, rs1553546668, rs1569017015, rs1569017045, rs1569017073, rs1555889090, rs1569017143, rs1569017148, rs1569017205, rs1179351306, rs1569017257, rs1569017337, rs1555889162, rs1568658507, rs1485894376, rs1561139569, rs1574716488, rs1553519865, rs1573946994, rs1573948129, rs121918812, rs1573950349, rs1573952908, rs1573964264, rs1573964628, rs372425457, rs1573984004, rs1574004452, rs1574005235, rs1574006637, rs1574006857, rs1574039742, rs121918801, rs1574051496, rs1574051665, rs1574060250, rs1574060717, rs1574169179, rs1574170908, rs121918774, rs1574192005, rs1574192998, rs1574201591, rs1574216450, rs1574223964, rs1574224274, rs1574225593, rs748267258, rs1553547380, rs1574263819, rs1574265144, rs762927460, rs1574266490, rs1574271827, rs1574302195, rs1574371399, rs1575603683, rs763339068, rs1588313568, rs1589416130, rs1592380672, rs1592148206, rs1592149793, rs1592149906, rs1592162415, rs1592162506, rs1596787821, rs1600755607, rs1600755429, rs1600731888, rs1601573302, rs1601566621, rs1601542702, rs1601542417, rs1600886270, rs1600766500, rs1574370981, rs1573962555, rs1574068971, rs1057524737, rs1574263047, rs1575601202, rs1554777464, rs1589393179, rs1597696047, rs1247507359, rs752927520, rs1473654961, rs1592380834, rs796053036, rs1573953706, rs1573973548, rs1573984110, rs1574007140, rs1574166948, rs745378416, rs1574209023, rs796053094, rs1574264920, rs1600714727, rs755159935, rs1574281711, rs779324355, rs1053767552, rs201894374, rs770456604, rs113094436, rs1578264574, rs1260191836, rs1578265048, rs1578265068, rs1578269200, rs1186496501, rs1578269761, rs756467468, rs1381665298, rs1578270476, rs1578274054, rs769243823, rs200059198, rs749975104, rs1578282133, rs1306655122, rs1600785769, rs1580990072, rs1584399108, rs1057519189, rs1595440453, rs1596872804, rs1597653264, rs1597676610, rs1599719527, rs1600755440, rs1600786071, rs770904422, rs1574525321, rs1840653547, rs749965674, rs1841611651, rs1841766225, rs1852152679, rs1853919580, rs1858669268, rs1941650264, rs1941714576, rs1938725748, rs2037920694, rs2037920791, rs2079949302, rs2079962041, rs2079972258, rs2080188103, rs2080189052, rs1057520773, rs2081071680, rs2081187047, rs2081187692, rs2081358991, rs2081378550, rs1698943949, rs1698602170, rs1698192456, rs1698176171, rs1369404945, rs1698003832, rs1698002491, rs1697999557, rs398123581, rs1697674296, rs1697473667, rs1697277384, rs1697160366, rs1697157422, rs1426666349, rs1697134047, rs1696883051, rs1696628056, rs794726823, rs1696403750, rs897883046, rs1696401617, rs1696356978, rs1696338792, rs1693176153, rs1692577292, rs1240187329, rs1553529527, rs1692166604, rs1691093633, rs1691039670, rs1690583220, rs1690345764, rs1690011364, rs1553521530, rs1553521051, rs1386425283, rs1573952473, rs1689300152, rs1689298888, rs1689285717, rs1689278461, rs1238612161, rs1689271621, rs1253117981, rs1689218857, rs1689211960, rs1689211569, rs1689200375, rs1689142827, rs1684673339, rs1684663586, rs1699367901, rs1553553462, rs1699149959, rs1698958802, rs746440689, rs1692586274, rs1697876590, rs727504142, rs1689985819, rs794726764, rs1704944478, rs1178244073, rs1840967817, rs2080693649, rs1938214529, rs2080696874, rs2081190512, rs1691073965, rs1689488709, rs1691048388, rs1692581621, rs1692870117, rs121918785, rs749539763, rs1842042825, rs2081190344, rs1600789325
Gilbert disease	Gilbert Disease (disorder), NON RARE IN EUROPE: Gilbert syndrome	rs72551349, rs62625011, rs34993780, rs72551351, rs748219743	7715297, 11013440, 9627603, 10421657, 15180166, 12139570, 15297419, 17496722
Hyperbilirubinemia	Hyperbilirubinemia, Unconjugated hyperbilirubinemia, Neonatal unconjugated hyperbilirubinemia, Hyperbilirubinemia, Neonatal, Indirect Hyperbilirubinemia, Neonatal	rs34993780, rs587784535, rs797046090, rs797046091	20194756, 25370011, 27060662, 21983082, 23950218, 28167773
Lucey-driscoll syndrome	Lucey-Driscoll syndrome (disorder)	rs34993780, rs3755319	23014115, 11061796
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315, rs121918316, rs397515320, rs121434489, rs1585215916, rs267607233, rs267606752, rs137852214, rs606231193, rs132630297, rs80338758, rs137852815, rs122455132, rs28935171, rs122453113, rs122445108, rs28934904, rs28934908, rs28935468, rs61748421, rs121918624, rs202060209, rs80338708, rs113994198, rs199422192, rs387906635, rs1554770064, rs1057519611, rs1060499526, rs387906636, rs1057519612, rs281875189, rs281875322, rs387906799, rs387906804, rs875989800, rs797045262, rs387906845, rs387906846, rs876657378, rs281875227, rs281875228, rs281875229, rs281875230, rs387906861, rs370667926, rs387906932, rs387906943, rs1557612719, rs387907190, rs387907191, rs2126499522, rs587776908, rs1560982564, rs80359505, rs398123009, rs587776929, rs587776930, rs397514555, rs398122824, rs398122825, rs397514556, rs2147483647, rs587776937, rs397514627, rs397514655, rs397514656, rs730882192, rs1587520018, rs1581995953, rs1554121970, rs1581987445, rs397514670, rs376395543, rs137854128, rs397509411, rs397509412, rs397514741, rs398122394, rs879255516, rs397518483, rs398122406, rs398122412, rs398123561, rs200667343, rs587777162, rs587777202, rs62507350, rs587777219, rs587777225, rs587777226, rs587779750, rs587777326, rs587777334, rs281875332, rs587780470, rs587780474, rs587780486, rs587777378, rs587777406, rs587777408, rs587777409, rs587777411, rs587777522, rs527236034, rs527236035, rs267608571, rs267608382, rs267608597, rs61753979, rs61751444, rs267608493, rs587777644, rs587777645, rs587777646, rs587777703, rs587779388, rs606231266, rs606231267, rs672601340, rs606231268, rs672601341, rs606231269, rs672601342, rs606231270, rs606231271, rs606231272, rs606231273, rs587784566, rs587784092, rs587783749, rs587783747, rs587783640, rs587783483, rs606231456, rs606231457, rs606231458, rs606231459, rs672601370, rs672601369, rs672601371, rs672601367, rs672601366, rs672601365, rs672601364, rs672601363, rs672601362, rs672601376, rs672601377, rs672601378, rs724159949, rs724159950, rs724159948, rs724159956, rs724159953, rs727502860, rs727502861, rs730882197, rs749995448, rs786205143, rs794726770, rs1135401808, rs786205583, rs786205595, rs786205859, rs794727792, rs794727928, rs794729221, rs797044519, rs797044523, rs797044521, rs797044524, rs797044526, rs797044522, rs797044520, rs794727642, rs796052719, rs781746113, rs796052510, rs796052733, rs796052724, rs796052728, rs796052676, rs796053353, rs796053366, rs796053368, rs1555103986, rs1555110818, rs796052571, rs1555110843, rs796052626, rs796052618, rs796053290, rs796052217, rs672601368, rs797045164, rs797044961, rs797044962, rs200070245, rs797044963, rs869320675, rs869320676, rs797045012, rs752746786, rs797044885, rs797044925, rs797044854, rs797044849, rs797044930, rs797044901, rs797044918, rs797044884, rs797045177, rs797045178, rs797045050, rs797045036, rs797045053, rs797045047, rs797045037, rs797045042, rs797045041, rs879255261, rs782397980, rs797045263, rs797045264, rs797045655, rs797045586, rs545185248, rs797046031, rs797046028, rs797046029, rs797046030, rs797045249, rs797045529, rs797045952, rs797045984, rs797045540, rs797045539, rs797045989, rs863224930, rs869025202, rs863225264, rs863225077, rs876661308, rs869025222, rs864309560, rs758252808, rs745756308, rs869025286, rs869025287, rs869025578, rs143038880, rs869025579, rs869025580, rs869025581, rs869312704, rs869312674, rs869312677, rs869312689, rs869312693, rs869312698, rs869312708, rs869312711, rs869312826, rs869312825, rs869312824, rs869312823, rs758432471, rs869312821, rs761993070, rs869312844, rs869312842, rs869312843, rs869312841, rs869312847, rs869320632, rs869312955, rs773432002, rs869320713, rs869320772, rs869320773, rs879255270, rs875989848, rs875989849, rs1716457622, rs2108414289, rs878854401, rs875989786, rs1085307109, rs1085307108, rs876657679, rs876661167, rs876661076, rs876661055, rs876661219, rs876661064, rs876661151, rs876661041, rs200440467, rs876661295, rs878853045, rs878853143, rs878853142, rs878853149, rs1555910048, rs878853152, rs878853146, rs878853145, rs878853141, rs878853151, rs878853144, rs878853148, rs878853147, rs878853251, rs878853269, rs879253762, rs886037841, rs879253888, rs879253931, rs879254016, rs879255618, rs879255619, rs879255620, rs886037847, rs879255621, rs886039332, rs746177928, rs886039520, rs886041003, rs886041058, rs750035706, rs886041059, rs886041060, rs886041061, rs886041090, rs886041088, rs886041089, rs886041095, rs886041097, rs886041989, rs886041944, rs886041692, rs886041593, rs886041687, rs886041207, rs886041309, rs886041239, rs886041448, rs138336847, rs149644940, rs886041295, rs886041521, rs886041125, rs886042041, rs886041238, rs886041469, rs886041197, rs886041291, rs886041658, rs886041705, rs886041876, rs139716296, rs1057516030, rs1057517408, rs749655461, rs141179774, rs370916968, rs1057517676, rs1057517933, rs1057517708, rs1057518352, rs1057518183, rs1057518474, rs1057518204, rs1057517825, rs1057518796, rs1057518961, rs1057518772, rs1057518988, rs1057519004, rs1057518700, rs772450541, rs371310428, rs1057519019, rs1057519491, rs1057519546, rs1057519560, rs1057519565, rs1057519400, rs1057519402, rs1057519405, rs1057519593, rs1057519594, rs1057519628, rs1556912828, rs1060505029, rs1060505030, rs147001633, rs1057519947, rs1057519617, rs1057524832, rs774592932, rs797045045, rs1039571136, rs1555910821, rs1060499626, rs1060499655, rs1554770185, rs1060499936, rs1060501153, rs1060501151, rs1064792984, rs1060503378, rs1060503386, rs1060503383, rs1060500046, rs1064792999, rs1060505033, rs1064796564, rs1064797002, rs1064793161, rs150802299, rs1064796830, rs1064794996, rs1064795444, rs1064796034, rs1064796403, rs1064794979, rs1064796765, rs1064793539, rs760933323, rs1064793546, rs1064796406, rs1064796367, rs780441716, rs1064794894, rs1064796023, rs1064797355, rs1085307484, rs1064794935, rs1085307547, rs1131690804, rs757511770, rs1131691875, rs1131691979, rs398122823, rs1131691866, rs1131692159, rs1131692228, rs1131692154, rs113331868, rs1554121872, rs1554121875, rs926027867, rs1554122123, rs1554122129, rs1287121256, rs1554122526, rs1554123982, rs1554385102, rs1554385111, rs1554385305, rs1554386687, rs1554389088, rs1554402092, rs1554434435, rs1135401778, rs1135401760, rs1135401770, rs1135401771, rs1135401768, rs1135401779, rs1135401805, rs1135401797, rs1135401799, rs1135401816, rs1135401823, rs1135401824, rs1555769968, rs1135401825, rs1135401955, rs1135401956, rs1135401957, rs1135401958, rs1554129040, rs1554150543, rs1553188463, rs1553146165, rs1485978447, rs1361547443, rs750079325, rs369692236, rs1554231836, rs749188610, rs1554122735, rs1554689877, rs1174482090, rs781053477, rs1554623112, rs1555409836, rs1555411305, rs770014321, rs1555984461, rs1555990958, rs762292772, rs1554944271, rs1057524157, rs1485749468, rs1555984343, rs1293450628, rs373584239, rs1553722309, rs1553738686, rs1376334317, rs1553722294, rs1553283831, rs1554120589, rs1555985554, rs1555877287, rs1555411378, rs750922282, rs1553264873, rs1554263326, rs1554264268, rs1554263626, rs1554263625, rs766614772, rs1553620494, rs1555050158, rs1555050165, rs1555050171, rs1555050174, rs765556214, rs1402086660, rs1554645052, rs1555661648, rs1293246328, rs749494995, rs775592405, rs1553265189, rs1553242856, rs1553247374, rs1553241570, rs1553997065, rs1553998565, rs1380822792, rs1555028154, rs1555023232, rs1553194155, rs1553130904, rs1553152590, rs1553567864, rs1553638614, rs120074160, rs1554486894, rs1554767754, rs1554843977, rs1555443581, rs1555443600, rs1555439545, rs1555525088, rs770680174, rs1555889130, rs373178770, rs1555985532, rs1553519853, rs781325598, rs1410587479, rs1553638086, rs150259543, rs1554093891, rs1554121228, rs1554120498, rs1554121189, rs1212517874, rs1554770628, rs1555979158, rs1554770054, rs771610568, rs1451230055, rs1554770624, rs1555906707, rs1555906768, rs1555906781, rs1555907620, rs1555907623, rs1555907626, rs1555907653, rs1555907864, rs1554094145, rs1554202698, rs1554200722, rs773327091, rs1555607621, rs1555604778, rs1555607159, rs1555607682, rs1553364018, rs1553324416, rs1555411394, rs1554102556, rs1554122363, rs1555705966, rs1555103971, rs1555408401, rs1554461593, rs1554304254, rs1554120978, rs1047509819, rs1555982601, rs767774867, rs1554789246, rs1555111511, rs1555950676, rs1555954380, rs1555985649, rs1553194162, rs1553518509, rs1274633498, rs1554274371, rs1554122252, rs1554122458, rs1554122729, rs1554297905, rs1554776342, rs1554770046, rs1554770667, rs1554792556, rs1452715535, rs1555444885, rs1555534147, rs1427624649, rs1555611722, rs1555744282, rs1555706391, rs1178702025, rs1555984102, rs1554770589, rs1554121443, rs1559791842, rs1559824939, rs1555889127, rs1236702036, rs1553510280, rs1553511175, rs1553511226, rs1554150552, rs1554275163, rs1554201137, rs1553517991, rs1553518511, rs1553517984, rs1553518752, rs1554119814, rs1554122293, rs1554122341, rs1554122689, rs1554770243, rs1554770444, rs1557045250, rs959316981, rs1556270312, rs1553270640, rs978179634, rs1554093884, rs1491240980, rs1555943484, rs1554121453, rs1334099693, rs1554048616, rs1555660806, rs1555644480, rs1555651572, rs1567844992, rs1567855081, rs1567855669, rs1567855704, rs1567856045, rs1567856331, rs1567860075, rs1567860112, rs1567860640, rs1567860891, rs754919272, rs1567860919, rs1567861468, rs1567861489, rs1567861501, rs1567861894, rs1567863732, rs1567864750, rs1567877108, rs1567878511, rs758785463, rs1553808301, rs1553245038, rs1553789166, rs1553813646, rs1553631860, rs1554121265, rs1554770262, rs1555034768, rs1555984433, rs779009256, rs1553994814, rs1553996086, rs1553996072, rs1553270599, rs1553153291, rs760262127, rs1554119274, rs1554121878, rs1554387293, rs1554385203, rs757077698, rs750612085, rs1554776500, rs1564360978, rs1554776933, rs1554776938, rs1565278132, rs1567368243, rs1558478047, rs375695605, rs1558479778, rs1558501648, rs1565240833, rs114727354, rs1557591264, rs1557620758, rs1559099927, rs1561788984, rs369459721, rs1563831738, rs1562159088, rs1562159562, rs1562159599, rs1559094754, rs1559328283, rs755634856, rs1561784687, rs1554122296, rs1561789313, rs1562720119, rs1564363665, rs1561697465, rs1561785003, rs1561787845, rs1561789215, rs1554122305, rs1561784553, rs1561784560, rs1561787690, rs1554122888, rs749632782, rs1567139896, rs1569370887, rs1569371303, rs1564493599, rs1561875779, rs1569146542, rs1569146649, rs1275489527, rs1560115921, rs1468772495, rs749969789, rs1560108090, rs1569376809, rs1569355102, rs1560103306, rs1564365418, rs1559855453, rs1562928193, rs1558149913, rs1253072668, rs141976414, rs1558371790, rs1557898800, rs1567758622, rs1567844041, rs1567844114, rs1567920106, rs1567920209, rs138247472, rs1567974030, rs1567995650, rs1283838287, rs1568003569, rs1568006217, rs1568018905, rs1562505675, rs1561783309, rs1555980234, rs1559087186, rs1560966086, rs1560330387, rs769471341, rs1562493608, rs1562505335, rs1554121861, rs1554122200, rs1562957809, rs1568097623, rs1391600900, rs1568234874, rs1568235086, rs1555990955, rs1567870541, rs1557570794, rs1562869207, rs1571818248, rs1431778557, rs369691608, rs1595808957, rs1597665063, rs1597846084, rs1603401125, rs1603350606, rs1601946481, rs1601932069, rs1602880906, rs1602308324, rs1574554519, rs1573882268, rs1603198937, rs1558148010, rs1558498928, rs1569459580, rs1569380375, rs1560062082, rs1557889974, rs1558414255, rs756429763, rs781663444, rs1569016820, rs1569017025, rs1569017160, rs1557612048, rs1568504941, rs1581987022, rs1576983339, rs1599892470, rs1265340906, rs1602284689, rs1574949440, rs1576220938, rs1576280892, rs1576288424, rs1574459612, rs1574511051, rs1575654528, rs1577094794, rs1294683568, rs771819481, rs1580984895, rs1581338441, rs1580988138, rs1581980317, rs1581986872, rs1554121207, rs1581987268, rs1581987476, rs1581987885, rs763770519, rs1581991929, rs1581992099, rs1581992998, rs1581995453, rs1554122242, rs1581996778, rs1581997228, rs1588735247, rs1555980467, rs1555985742, rs1601319086, rs1601970168, rs1574451881, rs876661168, rs1576994053, rs1573589807, rs1581036396, rs1601267617, rs1572531830, rs1573483715, rs1590954686, rs1601315812, rs1573965358, rs1573972562, rs529087882, rs1570609440, rs1598940393, rs1575333081, rs1576028676, rs1596476657, rs1599375711, rs1603290366, rs1603060007, rs1603069440, rs1592939069, rs1591612223, rs2062994512, rs373701249, rs1600471396, rs1600501018, rs1600504088, rs1600514073, rs748436953, rs765723607, rs758170522, rs1561785045, rs1357591960, rs1591609136, rs1596891223, rs1579370234, rs2047850664, rs1579109565, rs1870202051, rs1574887674, rs778229060, rs1572531281, rs1570622663, rs1573501865, rs1576086299, rs1576164991, rs1574907198, rs1576656734, rs1554121438, rs1581995425, rs1581996813, rs1582001015, rs1588324025, rs1591371152, rs1590008294, rs1590956245, rs1590028691, rs1591606580, rs1591611001, rs1591612317, rs1591612370, rs763436882, rs997044541, rs1595897117, rs747706524, rs1579377990, rs1201878175, rs1894051550, rs1572531730, rs1579576029, rs1577017863, rs752545577, rs1582461267, rs1589460606, rs1588727276, rs1598620094, rs1599368323, rs1600082188, rs1601319352, rs1598226304, rs2076013475, rs2076017638, rs1600596180, rs1554121932, rs1680676671, rs1570607996, rs1382444181, rs1570640673, rs1574994308, rs1596667777, rs1602226289, rs1595629181, rs1595609005, rs1227643933, rs1572705473, rs1570621899, rs1722830922, rs1575094649, rs1417035592, rs1581997098, rs1589457762, rs1598211790, rs758726258, rs1601071971, rs863224922, rs1586692481, rs1586692548, rs1586692551, rs1580988074, rs1594129609, rs1588732344, rs1579368865, rs1586660389, rs1586660370, rs1586660338, rs1586657848, rs1586660381, rs1791701214, rs752676391, rs1680673822, rs758098717, rs1726676630, rs762288077, rs1759964009, rs1760905766, rs1761021165, rs1554121934, rs2055849544, rs1049773, rs587784300, rs1861628072, rs1761241410, rs1064797322, rs1948652423, rs2059194330, rs1777174302, rs2054280202, rs2081190512, rs772665884, rs1400164869, rs1861593395, rs1760897843, rs1761087122, rs1388355040, rs2068797192, rs1777175608, rs376898131
Metabolic syndrome	Metabolic Syndrome X	rs367643250, rs587777380, rs777736953	30621171
Neutropenia	Neutropenia	rs879253882	17549067
Obesity	Obesity	rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562, rs121913564, rs193922650, rs193922685, rs193922687, rs751160202, rs747681609, rs1553400259, rs13447339, rs370479598, rs1554394014, rs1553174844, rs756232889, rs369841551, rs1557670950, rs1571321748, rs148538980, rs1572820988, rs1591461970, rs1419374563, rs745921568, rs144159890, rs1570714352, rs779783209, rs1573250294, rs1573254045, rs1580744791, rs1580746829	25246029

Unknown
Disease term	Disease name	Evidence	References	Source
Hodgkin lymphoma	Adult Hodgkin Lymphoma		18768784	ClinVar
Gilbert Disease	Gilbert syndrome			GenCC
Metabolic Syndrome	Metabolic Syndrome			GWAS
Cholelithiasis	Cholelithiasis			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Acute Kidney Injury	Associate	39522022
Adenocarcinoma	Associate	28056823, 28493308, 32058557, 35328047, 38250763
Adenocarcinoma of Lung	Associate	24047243, 35328047
Alopecia	Associate	25202035
alpha Thalassemia	Associate	16628735, 32751969
Anemia Hemolytic	Associate	34672909
Anemia Sickle Cell	Associate	15388579, 16628735, 17593033, 18392554, 18756540, 22558097, 23827693, 24060717, 24167350, 24204915, 26146896, 31619193
Asthenia	Associate	29504153
beta Thalassemia	Associate	11843828, 24204915
Bile Duct Diseases	Associate	40184140
Biliary Tract Neoplasms	Associate	26229432
Bone Marrow Diseases	Associate	21486535, 23892411
Breast Neoplasms	Inhibit	15318931
Breast Neoplasms	Associate	16280036, 17909964, 27525948, 28178648, 34886806
Bronchopulmonary Dysplasia	Associate	26666247
Carcinogenesis	Associate	25712374
Carcinoid Tumor	Associate	22450351
Carcinoma Hepatocellular	Associate	22447115, 23382909, 25288013, 26010150
Carcinoma Non Small Cell Lung	Associate	33090402
Carcinoma Renal Cell	Associate	31007253, 38131663
Carcinoma Squamous Cell	Associate	34887858, 35328047
Cardiotoxicity	Associate	38547766
Central Nervous System Infections	Associate	25319636, 29137095
Cerebral Palsy	Associate	39978853
Chemical and Drug Induced Liver Injury	Associate	26125716, 29386646, 31240859, 31640912
Cholangitis Sclerosing	Associate	40184140
Cholelithiasis	Associate	11843828, 16237771, 16628735, 17593033, 23207817, 24167350, 24204915, 26146896, 31602632, 32751969
Clear cell metastatic renal cell carcinoma	Associate	31640912
Clostridium Infections	Associate	35226656
Colitis Ulcerative	Associate	40184140
Colorectal Neoplasms	Associate	15280927, 15929176, 18594531, 18675828, 18797458, 19125128, 19859999, 20028383, 20096102, 20628391, 21287524, 21486535, 21654688, 23236239, 23892411, 24033692, 24244442, 25210794, 25545261, 25778466, 25782327, 25834402, 26710796, 26811156, 27122675, 27461651, 27938508, 28278081, 28637434, 29085228, 29358861, 30377777, 31533552, 32264830, 32323779, 32829105, 32878631, 33035787, 34327766, 35177165, 35226656, 35340156, 35822291
Conotruncal cardiac defects	Associate	36878495
Coronary Artery Disease	Associate	17952380, 18790042
Crigler Najjar Syndrome	Associate	15388579, 16171463, 17229650, 24065680, 24286076, 24793765, 25086287, 25319636, 26676689, 26716871, 30285761, 30544479, 31467903, 31553814, 32143638, 33485181, 34074250, 35436954, 35527687, 37759499, 39456788, 39881831, 9497253, 9639672
Crigler Najjar syndrome type 2	Associate	16269258, 17098698, 21319362, 24065680, 24401909, 25319636, 29137095, 30285761, 30544479, 31142299, 35436954, 9639672
Crohn Disease	Stimulate	35872023
Cystic Fibrosis	Associate	9639672
Death	Associate	21287524, 29085228
Dehydration	Associate	39978853
Developmental Disabilities	Associate	39978853
Diabetes Mellitus Type 2	Associate	26628212, 37445792
Diarrhea	Associate	15280927, 16456808, 16951398, 18300238, 19125128, 20628391, 23236239, 23892411, 24815493, 24958824, 25880011, 28397089, 28637434, 29131533, 29504153, 30447099, 30645764, 31558477, 32264830, 32357899, 33728696, 34860573, 35340156, 35822291, 36527823
Disease	Associate	15388579
Disease Resistance	Associate	37260062
Drug Related Side Effects and Adverse Reactions	Associate	15858133, 16965601, 18300238, 18832463, 20028383, 21287524, 21654688, 23840132, 24033692, 26229432, 26808671, 27461651, 27507617, 27883280, 28085011, 28474802, 28915895, 29052349, 29504153, 30246377, 30447099, 30585257, 30645764, 31558477, 32829105, 32899072, 33035787, 33348915, 33386925, 33728696, 34860573, 35226656, 36308049, 36527823, 9402181
Dyslipidemias	Associate	29220881
Endometrial Neoplasms	Associate	22633539
Enterocolitis Neutropenic	Associate	21486535
Epilepsy Tonic Clonic	Associate	11843828
Esophageal Neoplasms	Stimulate	22367021
Fabry Disease	Associate	17593033, 28951772
Fatigue	Associate	30645764
Febrile Neutropenia	Associate	21486535, 29530335, 30527181, 34998046, 35637361
Fibular hypoplasia and complex brachydactyly	Associate	35340156
Galactosemias	Associate	21319362
Gallbladder Diseases	Associate	18756540, 36055244
Gallstones	Associate	10498597, 11843828, 15388579, 17593033, 23207817, 24060717, 24167350, 26146896, 31619193
Gardner Syndrome	Associate	16269258, 27444220
Gastrointestinal Diseases	Associate	33728696
Gastrointestinal Neoplasms	Associate	27525948
Genetic Diseases Inborn	Associate	17229650, 28338110
Gilbert Disease	Associate	10498597, 11843828, 15388579, 15858133, 16269258, 16610035, 18832463, 20177420, 20389299, 20529348, 20924216, 21319362, 22135857, 22169899, 22299209, 22325916, 22450351, 23388413, 24587300, 24615032, 24620945, 25086287, 25319636, 26781906, 27444220, 28296739, 28321066, 28389660, 29137095, 29386646, 30285761, 30544479, 31017737, 31467903, 31602632, 32049823, 32571672, 33631237, 35426266, 35436954, 36274106, 36293566, 36639636, 37738404, 37759499, 39881831, 9402181, 9653159
Gilbert Disease	Inhibit	23388413, 28338110
Glucosephosphate Dehydrogenase Deficiency	Associate	26727668, 33622990, 33637102, 34895177
Glutaric Acidemia I	Associate	27557546
Hearing Loss	Associate	39978853
Heart Defects Congenital	Associate	36878495
Heart Failure	Associate	17978490, 37260062
Heart Septal Defects	Associate	36878495
Hematologic Diseases	Associate	15280927, 20628391, 21287524, 21892003, 23386248, 24033692, 24114122, 30246377
Hemolysis	Associate	24060717, 32049823, 34074250
Hepatitis C Chronic	Associate	28296739
Hereditary Angioedema Type III	Associate	27525948
HIV Infections	Associate	20890421, 23264445
Hodgkin Disease	Associate	18768784, 33671849
Hyperbilirubinemia	Associate	12502904, 15388579, 16170755, 17506482, 18756540, 20389299, 20647221, 20890421, 22169899, 22299209, 22307138, 23148286, 23207817, 24167350, 24204915, 24390949, 24557078, 24642571, 24898899, 25102181, 25319636, 26146841, 26375741, 26727668, 26781906, 27323053, 27557546, 28296739, 28399191, 29386646, 29534743, 31142299, 31467903, 32049823, 32571672, 32899072, 34074250, 34672909, 34895177, 35436954, 35501760, 35973199, 36293671, 36520959, 36580335, 38279097, 39978853, 9639672
Hyperbilirubinemia Neonatal	Associate	12502904, 22299209, 23388413, 25102181, 26146841, 27557546, 27980881, 28399191, 29534743, 29607327, 30298137, 32571672, 34074250, 34895177, 35501760, 36293671, 36520959, 38279097, 39978853
Hypersensitivity Immediate	Associate	26676689
Hypoglycemia	Associate	39978853
Jaundice	Associate	16170755, 18832463, 20668247, 22299209, 23388413, 30287871, 32751969, 33622990, 34625956, 35436954
Jaundice Chronic Idiopathic	Associate	36274106
Jaundice Neonatal	Associate	16623861, 17506482, 22299209, 23388413, 36520959
Kernicterus	Associate	20668247, 22299209, 26727668, 32571672, 9653159
Laryngeal Neoplasms	Associate	26751466
Leukemia Myeloid Acute	Associate	30016963, 36951168
Leukopenia	Associate	20860988, 29052349, 30447099, 35233973
Lung Diseases	Associate	25086287
Lung Neoplasms	Associate	27883280, 29052349, 31685767, 33090402, 35328047
Mucositis	Associate	33728696, 35340156
Multiple Sclerosis	Associate	30298137
Nausea	Associate	31558477
Neoplasm Metastasis	Associate	15929176
Neoplasms	Inhibit	15318931
Neoplasms	Associate	16280036, 16965601, 17627617, 20653675, 22450351, 23303296, 23963147, 24114122, 24244442, 24958824, 25210794, 25288013, 25712374, 26010150, 26125716, 26482555, 28085011, 32758288, 35340156
Neoplasms Squamous Cell	Associate	26482555, 33671849
Neoplastic Syndromes Hereditary	Associate	36274106
Neuropathy Hereditary Sensory And Autonomic Type I With Cough And Gastroesophageal Reflux	Associate	32758288
Neutropenia	Associate	17409981, 17627617, 18300238, 19349540, 19349543, 20177420, 20530282, 20628391, 20653675, 20860988, 21150467, 21486535, 21740478, 22516947, 23236239, 24033692, 24958824, 25778466, 25869015, 25880011, 26229432, 26710796, 27845419, 28637434, 29504153, 29530335, 30246377, 32778670, 34860573, 35340156, 35637361, 35822291, 36114233
Obesity	Associate	24901842
Obesity	Inhibit	27980881
Oculocutaneous albinism type 2	Associate	24401909
Osteoporosis	Associate	34462452
Pancreatic Neoplasms	Associate	25076337, 33386925, 34595239, 35637361
Precancerous Conditions	Associate	32323779
Prostatic Neoplasms	Associate	21771722
Psychotic Disorders	Associate	35197553
Rectal Neoplasms	Associate	30246377, 33119477
Respiratory Insufficiency	Associate	30421550
Respiratory Tract Diseases	Associate	26666247
Retinoblastoma	Associate	31207142
Scleroderma Limited	Associate	24114122
Shock Septic	Associate	29504153, 35987938
Small Cell Lung Carcinoma	Associate	25450281, 30527181, 33728696
Smoke Inhalation Injury	Associate	25086287
Spherocytosis Hereditary	Associate	10498597, 20924216, 21319362, 31122244, 34672909, 35650129, 37385619
Spinocerebellar Ataxia 11	Associate	32881938
Squamous Cell Carcinoma of Head and Neck	Associate	26751466
Stomach Neoplasms	Associate	25712374, 28056823, 32666389
Syndrome	Associate	15858133
Systemic carnitine deficiency	Associate	23827693
Tertiary Lymphoid Structures	Associate	32758288
Thalassemia	Associate	24060717
Thrombocytopenia	Associate	26313268
Unilateral Breast Neoplasms	Associate	36878495
Uterine Cervical Neoplasms	Associate	32758288
Vomiting	Associate	16456808, 35340156
Wilms Tumor	Associate	34327766