FBXL19 (F-box and leucine rich repeat protein 19)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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54620 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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F-box and leucine rich repeat protein 19 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FBXL19 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CXXC11, Fbl19, JHDM1C |
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Chromosome
Chromosome number
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16 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16p11.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q6PCT2 | ||||||||||||||||||||
| Protein name | F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) | ||||||||||||||||||||
| Protein function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that plays a role in different processes including cell migration, cell proliferation or cytoskeletal reorganization (PubMed:24684802, PubMed:2 | ||||||||||||||||||||
| PDB | 6ASB | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 694 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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