FBXL19 (F-box and leucine rich repeat protein 19)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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54620 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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F-box and leucine rich repeat protein 19 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FBXL19 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CXXC11, Fbl19, JHDM1C |
Chromosome
Chromosome number
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16 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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16p11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q6PCT2 | ||||||||||||||||||||
Protein name | F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) | ||||||||||||||||||||
Protein function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that plays a role in different processes including cell migration, cell proliferation or cytoskeletal reorganization (PubMed:24684802, PubMed:2 | ||||||||||||||||||||
PDB | 6ASB | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 694 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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