DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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54431 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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DnaJ heat shock protein family (Hsp40) member C10 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DNAJC10 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ERdj5, JPDI, MTHr, PDIA19 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q32.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||||||||||||
UniProt ID | Q8IXB1 | ||||||||||||||||||||||||||||||
Protein name | DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr) | ||||||||||||||||||||||||||||||
Protein function | Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native dis | ||||||||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 793 | ||||||||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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