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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96GG9 |
| Protein name |
DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene) |
| Protein function |
Part of an E3 ubiquitin ligase complex for neddylation (PubMed:18826954). Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes (PubMed:19617556, PubMed:23201271, PubMed:23401859, PubMed:26906416). Acts by bindin |
| PDB |
3TDU
, 3TDZ
, 4P5O
, 5UFI
, 5V83
, 5V86
, 5V88
, 6B5Q
, 6BG3
, 6BG5
, 6P5V
, 6P5W
, 6XOL
, 6XOM
, 6XON
, 6XOO
, 6XOP
, 6XOQ
, 7KWA
, 8OR2
, 8OR3
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| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
| PF14555 |
UBA_4 |
9 → 50 |
|
Domain |
| PF03556 |
Cullin_binding |
136 → 246 |
Cullin binding |
Family |
|
| Tissue specificity |
TISSUE SPECIFICITY: Expressed in pancreas, kidney, placenta, brain and heart. Weakly or not expressed in liver, skeletal muscle and lung. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carci |
| Sequence |
|
| Sequence length |
259 |
| Interactions |
View interactions |