Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	53405
Gene name Gene Name - the full gene name approved by the HGNC.	Chloride intracellular channel 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CLIC5
Synonyms (NCBI Gene) Gene synonyms aliases	DFNB102, DFNB103, MST130, MSTP130
Disease Acronyms (UniProt) Disease acronyms from UniProt database	DFNB102, DFNB103
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p21.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia form

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SNP ID	Visualize variation	Clinical significance	Consequence
rs189893797	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, missense variant
rs199808624	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, non coding transcript variant, missense variant
rs606231308	A>T	Pathogenic	5 prime UTR variant, coding sequence variant, non coding transcript variant, genic upstream transcript variant, stop gained
rs1043716893	C>G,T	Likely-pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained, missense variant, non coding transcript variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT718083	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT718082	hsa-miR-4301	HITS-CLIP	19536157
MIRT718081	hsa-miR-5193	HITS-CLIP	19536157
MIRT718080	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT718079	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT718078	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718077	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718076	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718075	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718074	hsa-miR-6802-3p	HITS-CLIP	19536157
MIRT718073	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT718072	hsa-miR-4279	HITS-CLIP	19536157
MIRT718083	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT718082	hsa-miR-4301	HITS-CLIP	19536157
MIRT718081	hsa-miR-5193	HITS-CLIP	19536157
MIRT718080	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT718079	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT718078	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718077	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718076	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718075	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718074	hsa-miR-6802-3p	HITS-CLIP	19536157
MIRT718073	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT718072	hsa-miR-4279	HITS-CLIP	19536157
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT636614	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT636613	hsa-miR-4282	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT659473	hsa-miR-5579-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT659472	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT636614	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT636613	hsa-miR-4282	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624327	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624325	hsa-miR-3182	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT443457	hsa-miR-1252-3p	PAR-CLIP	22100165
MIRT443456	hsa-miR-5680	PAR-CLIP	22100165
MIRT443455	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT443453	hsa-miR-4251	PAR-CLIP	22100165
MIRT443454	hsa-miR-539-5p	PAR-CLIP	22100165
MIRT443452	hsa-miR-4480	PAR-CLIP	22100165
MIRT443451	hsa-miR-4663	PAR-CLIP	22100165
MIRT443450	hsa-miR-7160-5p	PAR-CLIP	22100165
MIRT443449	hsa-miR-8077	PAR-CLIP	22100165
MIRT443448	hsa-miR-6807-5p	PAR-CLIP	22100165
MIRT443447	hsa-miR-628-5p	PAR-CLIP	22100165
MIRT718083	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT718082	hsa-miR-4301	HITS-CLIP	19536157
MIRT718081	hsa-miR-5193	HITS-CLIP	19536157
MIRT718080	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT718079	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT718078	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718077	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718076	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718075	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718074	hsa-miR-6802-3p	HITS-CLIP	19536157
MIRT718073	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT718072	hsa-miR-4279	HITS-CLIP	19536157
MIRT718083	hsa-miR-500b-3p	HITS-CLIP	19536157
MIRT718082	hsa-miR-4301	HITS-CLIP	19536157
MIRT718081	hsa-miR-5193	HITS-CLIP	19536157
MIRT718080	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT718079	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT718078	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718077	hsa-miR-412-3p	HITS-CLIP	19536157
MIRT718076	hsa-miR-6754-3p	HITS-CLIP	19536157
MIRT718075	hsa-miR-6837-3p	HITS-CLIP	19536157
MIRT718074	hsa-miR-6802-3p	HITS-CLIP	19536157
MIRT718073	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT718072	hsa-miR-4279	HITS-CLIP	19536157
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT636614	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT636613	hsa-miR-4282	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT659473	hsa-miR-5579-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT659472	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT636614	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT636613	hsa-miR-4282	HITS-CLIP	23824327
MIRT636612	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT636611	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT636610	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT636609	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT636608	hsa-miR-8073	HITS-CLIP	23824327
MIRT636607	hsa-miR-6868-5p	HITS-CLIP	23824327
MIRT636606	hsa-miR-34a-5p	HITS-CLIP	23824327
MIRT636605	hsa-miR-34c-5p	HITS-CLIP	23824327
MIRT636604	hsa-miR-449a	HITS-CLIP	23824327
MIRT636603	hsa-miR-449b-5p	HITS-CLIP	23824327
MIRT636602	hsa-miR-548au-3p	HITS-CLIP	23824327
MIRT636601	hsa-miR-5096	HITS-CLIP	23824327
MIRT636600	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT624332	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT624331	hsa-miR-105-5p	HITS-CLIP	23824327
MIRT624330	hsa-miR-7853-5p	HITS-CLIP	23824327
MIRT624329	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT624328	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT624327	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT624326	hsa-miR-4469	HITS-CLIP	23824327
MIRT624325	hsa-miR-3182	HITS-CLIP	23824327
MIRT624324	hsa-miR-3671	HITS-CLIP	23824327
MIRT624323	hsa-miR-6826-3p	HITS-CLIP	23824327
MIRT624322	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT624321	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT624320	hsa-miR-3686	HITS-CLIP	23824327
MIRT624319	hsa-miR-607	HITS-CLIP	23824327
MIRT443457	hsa-miR-1252-3p	PAR-CLIP	22100165
MIRT443456	hsa-miR-5680	PAR-CLIP	22100165
MIRT443455	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT443453	hsa-miR-4251	PAR-CLIP	22100165
MIRT443454	hsa-miR-539-5p	PAR-CLIP	22100165
MIRT443452	hsa-miR-4480	PAR-CLIP	22100165
MIRT443451	hsa-miR-4663	PAR-CLIP	22100165
MIRT443450	hsa-miR-7160-5p	PAR-CLIP	22100165
MIRT443449	hsa-miR-8077	PAR-CLIP	22100165
MIRT443448	hsa-miR-6807-5p	PAR-CLIP	22100165
MIRT443447	hsa-miR-628-5p	PAR-CLIP	22100165
MIRT896366	hsa-miR-122	CLIP-seq
MIRT896367	hsa-miR-216b	CLIP-seq
MIRT896368	hsa-miR-3074-5p	CLIP-seq
MIRT896369	hsa-miR-3180-5p	CLIP-seq
MIRT896370	hsa-miR-342-5p	CLIP-seq
MIRT896371	hsa-miR-3611	CLIP-seq
MIRT896372	hsa-miR-3675-3p	CLIP-seq
MIRT896373	hsa-miR-3677-5p	CLIP-seq
MIRT896374	hsa-miR-432	CLIP-seq
MIRT896375	hsa-miR-4453	CLIP-seq
MIRT896376	hsa-miR-4506	CLIP-seq
MIRT896377	hsa-miR-4538	CLIP-seq
MIRT896378	hsa-miR-4651	CLIP-seq
MIRT896379	hsa-miR-4664-5p	CLIP-seq
MIRT896380	hsa-miR-4722-3p	CLIP-seq
MIRT896381	hsa-miR-4757-5p	CLIP-seq
MIRT896382	hsa-miR-516a-3p	CLIP-seq
MIRT896383	hsa-miR-520a-5p	CLIP-seq
MIRT896384	hsa-miR-525-5p	CLIP-seq
MIRT896385	hsa-miR-608	CLIP-seq
MIRT896386	hsa-miR-618	CLIP-seq
MIRT896387	hsa-miR-646	CLIP-seq
MIRT896388	hsa-miR-1178	CLIP-seq
MIRT896389	hsa-miR-1227	CLIP-seq
MIRT896390	hsa-miR-134	CLIP-seq
MIRT896391	hsa-miR-298	CLIP-seq
MIRT896368	hsa-miR-3074-5p	CLIP-seq
MIRT896392	hsa-miR-3118	CLIP-seq
MIRT896393	hsa-miR-3145-3p	CLIP-seq
MIRT896394	hsa-miR-3155	CLIP-seq
MIRT896395	hsa-miR-3155b	CLIP-seq
MIRT896396	hsa-miR-3160-5p	CLIP-seq
MIRT896397	hsa-miR-3164	CLIP-seq
MIRT896398	hsa-miR-3185	CLIP-seq
MIRT896399	hsa-miR-4303	CLIP-seq
MIRT896400	hsa-miR-4522	CLIP-seq
MIRT896401	hsa-miR-4677-3p	CLIP-seq
MIRT896402	hsa-miR-4678	CLIP-seq
MIRT896403	hsa-miR-4679	CLIP-seq
MIRT896404	hsa-miR-4698	CLIP-seq
MIRT896405	hsa-miR-4714-5p	CLIP-seq
MIRT896406	hsa-miR-4715-3p	CLIP-seq
MIRT896380	hsa-miR-4722-3p	CLIP-seq
MIRT896407	hsa-miR-4743	CLIP-seq
MIRT896408	hsa-miR-4762-3p	CLIP-seq
MIRT896409	hsa-miR-4772-5p	CLIP-seq
MIRT896410	hsa-miR-484	CLIP-seq
MIRT896382	hsa-miR-516a-3p	CLIP-seq
MIRT896382	hsa-miR-516a-3p	CLIP-seq
MIRT1965780	hsa-miR-3192	CLIP-seq
MIRT2201709	hsa-miR-103a	CLIP-seq
MIRT2201710	hsa-miR-107	CLIP-seq
MIRT2201711	hsa-miR-1179	CLIP-seq
MIRT2201712	hsa-miR-1184	CLIP-seq
MIRT2201713	hsa-miR-4269	CLIP-seq
MIRT2201714	hsa-miR-4310	CLIP-seq
MIRT2201715	hsa-miR-4420	CLIP-seq
MIRT2201716	hsa-miR-4514	CLIP-seq
MIRT2201717	hsa-miR-4692	CLIP-seq
MIRT2201718	hsa-miR-4742-5p	CLIP-seq
MIRT2201719	hsa-miR-503	CLIP-seq
MIRT2201720	hsa-miR-511	CLIP-seq
MIRT2201721	hsa-miR-634	CLIP-seq
MIRT2201722	hsa-miR-940	CLIP-seq
MIRT2386175	hsa-miR-4271	CLIP-seq
MIRT2386176	hsa-miR-4725-3p	CLIP-seq
MIRT2442083	hsa-miR-3977	CLIP-seq
MIRT2447176	hsa-miR-1245b-5p	CLIP-seq
MIRT2447177	hsa-miR-3142	CLIP-seq
MIRT2447178	hsa-miR-3620	CLIP-seq
MIRT2447179	hsa-miR-3653	CLIP-seq
MIRT2447180	hsa-miR-4263	CLIP-seq
MIRT2447181	hsa-miR-4426	CLIP-seq
MIRT2447182	hsa-miR-4493	CLIP-seq
MIRT2447183	hsa-miR-4647	CLIP-seq
MIRT2447184	hsa-miR-4662b	CLIP-seq
MIRT2447185	hsa-miR-4699-5p	CLIP-seq
MIRT2447186	hsa-miR-548n	CLIP-seq
MIRT2447187	hsa-miR-548t	CLIP-seq
MIRT2447188	hsa-miR-561	CLIP-seq
MIRT2447189	hsa-miR-576-5p	CLIP-seq
MIRT2201721	hsa-miR-634	CLIP-seq
MIRT2504629	hsa-miR-127-5p	CLIP-seq
MIRT2504630	hsa-miR-1289	CLIP-seq
MIRT2504631	hsa-miR-23a	CLIP-seq
MIRT2504632	hsa-miR-23b	CLIP-seq
MIRT2504633	hsa-miR-23c	CLIP-seq
MIRT2504634	hsa-miR-3135b	CLIP-seq
MIRT2504635	hsa-miR-3198	CLIP-seq
MIRT2504636	hsa-miR-320e	CLIP-seq
MIRT2447178	hsa-miR-3620	CLIP-seq
MIRT2442083	hsa-miR-3977	CLIP-seq
MIRT2504637	hsa-miR-4294	CLIP-seq
MIRT2504638	hsa-miR-4309	CLIP-seq
MIRT2504639	hsa-miR-4717-3p	CLIP-seq
MIRT2201720	hsa-miR-511	CLIP-seq
MIRT2201721	hsa-miR-634	CLIP-seq
MIRT2504640	hsa-miR-924	CLIP-seq
MIRT2504631	hsa-miR-23a	CLIP-seq
MIRT2504632	hsa-miR-23b	CLIP-seq
MIRT2504633	hsa-miR-23c	CLIP-seq
MIRT2447178	hsa-miR-3620	CLIP-seq
MIRT2442083	hsa-miR-3977	CLIP-seq
MIRT2504639	hsa-miR-4717-3p	CLIP-seq
MIRT2201720	hsa-miR-511	CLIP-seq
MIRT2201721	hsa-miR-634	CLIP-seq

Show/Hide all(18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005244	Function	Voltage-gated ion channel activity	IEA
GO:0005254	Function	Chloride channel activity	IEA
GO:0005515	Function	Protein binding	IPI	10793131, 16831863
GO:0005794	Component	Golgi apparatus	IEA
GO:0005815	Component	Microtubule organizing center	IEA
GO:0005938	Component	Cell cortex	IEA
GO:0006749	Process	Glutathione metabolic process	IEA
GO:0006821	Process	Chloride transport	IDA	10793131
GO:0007565	Process	Female pregnancy	TAS	10793131
GO:0007601	Process	Visual perception	IEA
GO:0007605	Process	Sensory perception of sound	IMP	24781754
GO:0015629	Component	Actin cytoskeleton	IDA	10793131
GO:0016324	Component	Apical plasma membrane	IEA
GO:0034707	Component	Chloride channel complex	IEA
GO:0034765	Process	Regulation of ion transmembrane transport	IEA
GO:0050896	Process	Response to stimulus	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:1902476	Process	Chloride transmembrane transport	IEA

MIM	HGNC	e!Ensembl
607293	13517	ENSG00000112782

Protein

UniProt ID

Q9NZA1

Protein name

Chloride intracellular channel protein 5 (Glutaredoxin-like oxidoreductase CLIC5) (EC 1.8.-.-)

Protein function

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (By similarity). Can insert into membranes and form non-selective ion channels almost equally permeable to Na(+), K(+

PDB

6Y2H , 8Q4I , 8Q4J

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13409	GST_N_2	190 → 254	Glutathione S-transferase, N-terminal domain	Domain
PF13410	GST_C_2	273 → 379		Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level). {ECO:0000269|PubMed:20335315, ECO:0000269|PubMed:24781754}.

Sequence

MNDEDYSTIYDTIQNERTYEVPDQPEENESPHYDDVHEYLRPENDLYATQLNTHEYDFVS
VYTIKGEETSLASVQSEDRGYLLPDEIYSELQEAHPGEPQEDRGISMEGLYSSTQDQQLC
AAELQENGSVMKEDLPSPSSFTIQHSKAFSTTKYSCYSDAEGLEEKEGAHMNPEIYLFVK
AGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDV
KTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGL
TKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKK
YRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS

Sequence length

410

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Deafness	DEAFNESS, AUTOSOMAL RECESSIVE (disorder), DEAFNESS, AUTOSOMAL RECESSIVE 103	rs267607135, rs387906219, rs387906220, rs387906221, rs387906222, rs606231120, rs267606855, rs121918370, rs137853185, rs137853186, rs137853187, rs137853188, rs587776522, rs587776523, rs200781822 View all (1019 more)	24781754, 17021174, 24285636
Hearing loss	Sensorineural Hearing Loss (disorder)	rs267607135, rs267606855, rs779841884, rs267606854, rs28942097, rs121908073, rs121908076, rs74315289, rs121908144, rs111033313, rs74315437, rs121908348, rs121908349, rs121908350, rs397515359 View all (184 more)

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Ischemic Stroke	Ischemic Stroke	GWAS
Diabetes	Diabetes	GWAS

Show/Hide Text Mining Associations (13)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	24172169
Carcinoma Hepatocellular	Associate	34766585
Cataract	Associate	37511188
Diabetic Nephropathies	Associate	36092962, 37492198
Diabetic Nephropathies	Inhibit	37916327
Hearing Loss	Associate	24781754, 33114113
Kidney Diseases	Associate	24781754
Neoplasms	Associate	34766585
Nonsyndromic Deafness	Associate	33114113
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	27540136
Sensorineural Deafness With Mild Renal Dysfunction	Associate	24781754
Small Cell Lung Carcinoma	Associate	35845940
Vestibular Diseases	Associate	24781754

CLIC5 (chloride intracellular channel 5)