Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5337
Gene name Gene Name - the full gene name approved by the HGNC.	Phospholipase D1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PLD1
Synonyms (NCBI Gene) Gene synonyms aliases	CVDD, CVDP1
Disease Acronyms (UniProt) Disease acronyms from UniProt database	CVDP1
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q26.31
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternativ

Show/Hide all(4)

SNP ID	Visualize variation	Clinical significance	Consequence
rs556433569	T>C	Likely-pathogenic	Non coding transcript variant, missense variant, coding sequence variant
rs769669104	T>C,G	Pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs778311238	TG>-	Pathogenic	Non coding transcript variant, coding sequence variant, frameshift variant
rs1085307450	A>C,G	Pathogenic	Splice donor variant

Show/Hide all(226)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031003	hsa-miR-21-5p	Microarray	18591254
MIRT732277	hsa-miR-638	Immunohistochemistry, Luciferase reporter assay, Microarray	26250158
MIRT732277	hsa-miR-638	Immunohistochemistry, Luciferase reporter assay, Microarray	26250158
MIRT734484	hsa-miR-122-5p	Luciferase reporter assay, Western blotting, qRT-PCR	32337269
MIRT736754	hsa-miR-320a	Flow cytometry	32725633
MIRT736755	hsa-miR-4496	Western blotting	32725633
MIRT1240237	hsa-miR-1238	CLIP-seq
MIRT1240238	hsa-miR-3200-5p	CLIP-seq
MIRT1240239	hsa-miR-4303	CLIP-seq
MIRT1240240	hsa-miR-4328	CLIP-seq
MIRT1240241	hsa-miR-103a	CLIP-seq
MIRT1240242	hsa-miR-107	CLIP-seq
MIRT1240243	hsa-miR-1184	CLIP-seq
MIRT1240244	hsa-miR-1587	CLIP-seq
MIRT1240245	hsa-miR-3908	CLIP-seq
MIRT1240246	hsa-miR-409-3p	CLIP-seq
MIRT1240247	hsa-miR-4492	CLIP-seq
MIRT1240248	hsa-miR-4498	CLIP-seq
MIRT1240249	hsa-miR-4656	CLIP-seq
MIRT1240250	hsa-miR-4675	CLIP-seq
MIRT1240251	hsa-miR-4741	CLIP-seq
MIRT1240252	hsa-miR-762	CLIP-seq
MIRT2070657	hsa-miR-4775	CLIP-seq
MIRT2070658	hsa-miR-590-3p	CLIP-seq
MIRT2297808	hsa-miR-4712-3p	CLIP-seq
MIRT2070657	hsa-miR-4775	CLIP-seq
MIRT2070658	hsa-miR-590-3p	CLIP-seq
MIRT1240241	hsa-miR-103a	CLIP-seq
MIRT2595230	hsa-miR-106a	CLIP-seq
MIRT2595231	hsa-miR-106b	CLIP-seq
MIRT1240242	hsa-miR-107	CLIP-seq
MIRT2595232	hsa-miR-1236	CLIP-seq
MIRT2595233	hsa-miR-1245b-3p	CLIP-seq
MIRT2595234	hsa-miR-1256	CLIP-seq
MIRT2595235	hsa-miR-1257	CLIP-seq
MIRT2595236	hsa-miR-125a-5p	CLIP-seq
MIRT2595237	hsa-miR-125b	CLIP-seq
MIRT2595238	hsa-miR-1262	CLIP-seq
MIRT2595239	hsa-miR-127-5p	CLIP-seq
MIRT2595240	hsa-miR-1323	CLIP-seq
MIRT2595241	hsa-miR-134	CLIP-seq
MIRT2595242	hsa-miR-142-5p	CLIP-seq
MIRT2595243	hsa-miR-148a	CLIP-seq
MIRT2595244	hsa-miR-148b	CLIP-seq
MIRT2595245	hsa-miR-152	CLIP-seq
MIRT2595246	hsa-miR-15a	CLIP-seq
MIRT2595247	hsa-miR-15b	CLIP-seq
MIRT2595248	hsa-miR-16	CLIP-seq
MIRT2595249	hsa-miR-17	CLIP-seq
MIRT2595250	hsa-miR-188-5p	CLIP-seq
MIRT2595251	hsa-miR-1909	CLIP-seq
MIRT2595252	hsa-miR-195	CLIP-seq
MIRT2595253	hsa-miR-202	CLIP-seq
MIRT2595254	hsa-miR-203	CLIP-seq
MIRT2595255	hsa-miR-20a	CLIP-seq
MIRT2595256	hsa-miR-20b	CLIP-seq
MIRT2595257	hsa-miR-2113	CLIP-seq
MIRT2595258	hsa-miR-217	CLIP-seq
MIRT2595259	hsa-miR-218	CLIP-seq
MIRT2595260	hsa-miR-223	CLIP-seq
MIRT2595261	hsa-miR-27a	CLIP-seq
MIRT2595262	hsa-miR-27b	CLIP-seq
MIRT2595263	hsa-miR-3074-3p	CLIP-seq
MIRT2595264	hsa-miR-3117-5p	CLIP-seq
MIRT2595265	hsa-miR-3118	CLIP-seq
MIRT2595266	hsa-miR-3136-5p	CLIP-seq
MIRT2595267	hsa-miR-3140-5p	CLIP-seq
MIRT2595268	hsa-miR-3148	CLIP-seq
MIRT2595269	hsa-miR-3180-5p	CLIP-seq
MIRT2595270	hsa-miR-3182	CLIP-seq
MIRT2595271	hsa-miR-3185	CLIP-seq
MIRT2595272	hsa-miR-324-5p	CLIP-seq
MIRT2595273	hsa-miR-346	CLIP-seq
MIRT2595274	hsa-miR-3609	CLIP-seq
MIRT2595275	hsa-miR-361-5p	CLIP-seq
MIRT2595276	hsa-miR-3668	CLIP-seq
MIRT2595277	hsa-miR-3920	CLIP-seq
MIRT2595278	hsa-miR-3977	CLIP-seq
MIRT2595279	hsa-miR-424	CLIP-seq
MIRT2595280	hsa-miR-4257	CLIP-seq
MIRT2595281	hsa-miR-4268	CLIP-seq
MIRT2595282	hsa-miR-4282	CLIP-seq
MIRT2595283	hsa-miR-4310	CLIP-seq
MIRT2595284	hsa-miR-4318	CLIP-seq
MIRT2595285	hsa-miR-4319	CLIP-seq
MIRT2595286	hsa-miR-4327	CLIP-seq
MIRT2595287	hsa-miR-4418	CLIP-seq
MIRT2595288	hsa-miR-4420	CLIP-seq
MIRT2595289	hsa-miR-4436a	CLIP-seq
MIRT2595290	hsa-miR-4436b-3p	CLIP-seq
MIRT2595291	hsa-miR-4439	CLIP-seq
MIRT2595292	hsa-miR-4448	CLIP-seq
MIRT2595293	hsa-miR-4452	CLIP-seq
MIRT2595294	hsa-miR-4457	CLIP-seq
MIRT2595295	hsa-miR-4468	CLIP-seq
MIRT2595296	hsa-miR-448	CLIP-seq
MIRT2595297	hsa-miR-4513	CLIP-seq
MIRT2595298	hsa-miR-4635	CLIP-seq
MIRT2595299	hsa-miR-4637	CLIP-seq
MIRT2595300	hsa-miR-4652-3p	CLIP-seq
MIRT2595301	hsa-miR-4653-3p	CLIP-seq
MIRT2595302	hsa-miR-4680-3p	CLIP-seq
MIRT2595303	hsa-miR-4688	CLIP-seq
MIRT2595304	hsa-miR-4693-5p	CLIP-seq
MIRT2595305	hsa-miR-4697-3p	CLIP-seq
MIRT2595306	hsa-miR-4701-3p	CLIP-seq
MIRT2595307	hsa-miR-4705	CLIP-seq
MIRT2595308	hsa-miR-4709-3p	CLIP-seq
MIRT2595309	hsa-miR-4732-3p	CLIP-seq
MIRT2595310	hsa-miR-4732-5p	CLIP-seq
MIRT2595311	hsa-miR-4742-3p	CLIP-seq
MIRT2595312	hsa-miR-4753-3p	CLIP-seq
MIRT2595313	hsa-miR-4760-3p	CLIP-seq
MIRT2595314	hsa-miR-4761-3p	CLIP-seq
MIRT2595315	hsa-miR-4768-5p	CLIP-seq
MIRT2070657	hsa-miR-4775	CLIP-seq
MIRT2595316	hsa-miR-4778-5p	CLIP-seq
MIRT2595317	hsa-miR-4789-3p	CLIP-seq
MIRT2595318	hsa-miR-4796-3p	CLIP-seq
MIRT2595319	hsa-miR-488	CLIP-seq
MIRT2595320	hsa-miR-497	CLIP-seq
MIRT2595321	hsa-miR-509-3-5p	CLIP-seq
MIRT2595322	hsa-miR-509-5p	CLIP-seq
MIRT2595323	hsa-miR-513a-3p	CLIP-seq
MIRT2595324	hsa-miR-513a-5p	CLIP-seq
MIRT2595325	hsa-miR-513b	CLIP-seq
MIRT2595326	hsa-miR-519d	CLIP-seq
MIRT2595327	hsa-miR-520a-5p	CLIP-seq
MIRT2595328	hsa-miR-525-5p	CLIP-seq
MIRT2595329	hsa-miR-548ah	CLIP-seq
MIRT2595330	hsa-miR-548g	CLIP-seq
MIRT2595331	hsa-miR-548o	CLIP-seq
MIRT2595332	hsa-miR-570	CLIP-seq
MIRT2595333	hsa-miR-579	CLIP-seq
MIRT2070658	hsa-miR-590-3p	CLIP-seq
MIRT2595334	hsa-miR-630	CLIP-seq
MIRT2595335	hsa-miR-635	CLIP-seq
MIRT2595336	hsa-miR-670	CLIP-seq
MIRT2595337	hsa-miR-671-5p	CLIP-seq
MIRT2595338	hsa-miR-759	CLIP-seq
MIRT2595339	hsa-miR-877	CLIP-seq
MIRT2595340	hsa-miR-892a	CLIP-seq
MIRT2595341	hsa-miR-93	CLIP-seq
MIRT2595342	hsa-miR-934	CLIP-seq
MIRT1240241	hsa-miR-103a	CLIP-seq
MIRT1240242	hsa-miR-107	CLIP-seq
MIRT2595232	hsa-miR-1236	CLIP-seq
MIRT2595233	hsa-miR-1245b-3p	CLIP-seq
MIRT2595234	hsa-miR-1256	CLIP-seq
MIRT2595235	hsa-miR-1257	CLIP-seq
MIRT2595236	hsa-miR-125a-5p	CLIP-seq
MIRT2595237	hsa-miR-125b	CLIP-seq
MIRT2595238	hsa-miR-1262	CLIP-seq
MIRT2595239	hsa-miR-127-5p	CLIP-seq
MIRT2595241	hsa-miR-134	CLIP-seq
MIRT2595243	hsa-miR-148a	CLIP-seq
MIRT2595244	hsa-miR-148b	CLIP-seq
MIRT2595245	hsa-miR-152	CLIP-seq
MIRT2595246	hsa-miR-15a	CLIP-seq
MIRT2595247	hsa-miR-15b	CLIP-seq
MIRT2595248	hsa-miR-16	CLIP-seq
MIRT2595250	hsa-miR-188-5p	CLIP-seq
MIRT2595251	hsa-miR-1909	CLIP-seq
MIRT2595252	hsa-miR-195	CLIP-seq
MIRT2595254	hsa-miR-203	CLIP-seq
MIRT2595257	hsa-miR-2113	CLIP-seq
MIRT2595259	hsa-miR-218	CLIP-seq
MIRT2595260	hsa-miR-223	CLIP-seq
MIRT2595261	hsa-miR-27a	CLIP-seq
MIRT2595262	hsa-miR-27b	CLIP-seq
MIRT2595264	hsa-miR-3117-5p	CLIP-seq
MIRT2595265	hsa-miR-3118	CLIP-seq
MIRT2595266	hsa-miR-3136-5p	CLIP-seq
MIRT2595268	hsa-miR-3148	CLIP-seq
MIRT2595269	hsa-miR-3180-5p	CLIP-seq
MIRT2595270	hsa-miR-3182	CLIP-seq
MIRT2595271	hsa-miR-3185	CLIP-seq
MIRT2595272	hsa-miR-324-5p	CLIP-seq
MIRT2595273	hsa-miR-346	CLIP-seq
MIRT2595276	hsa-miR-3668	CLIP-seq
MIRT2595277	hsa-miR-3920	CLIP-seq
MIRT2595279	hsa-miR-424	CLIP-seq
MIRT2595281	hsa-miR-4268	CLIP-seq
MIRT2595282	hsa-miR-4282	CLIP-seq
MIRT2595283	hsa-miR-4310	CLIP-seq
MIRT2595284	hsa-miR-4318	CLIP-seq
MIRT2595285	hsa-miR-4319	CLIP-seq
MIRT2595289	hsa-miR-4436a	CLIP-seq
MIRT2595290	hsa-miR-4436b-3p	CLIP-seq
MIRT2595291	hsa-miR-4439	CLIP-seq
MIRT2595292	hsa-miR-4448	CLIP-seq
MIRT2595294	hsa-miR-4457	CLIP-seq
MIRT2595295	hsa-miR-4468	CLIP-seq
MIRT2595297	hsa-miR-4513	CLIP-seq
MIRT2595298	hsa-miR-4635	CLIP-seq
MIRT2595299	hsa-miR-4637	CLIP-seq
MIRT2595301	hsa-miR-4653-3p	CLIP-seq
MIRT2595303	hsa-miR-4688	CLIP-seq
MIRT2595304	hsa-miR-4693-5p	CLIP-seq
MIRT2595305	hsa-miR-4697-3p	CLIP-seq
MIRT2595306	hsa-miR-4701-3p	CLIP-seq
MIRT2595307	hsa-miR-4705	CLIP-seq
MIRT2595309	hsa-miR-4732-3p	CLIP-seq
MIRT2595310	hsa-miR-4732-5p	CLIP-seq
MIRT2595311	hsa-miR-4742-3p	CLIP-seq
MIRT2595312	hsa-miR-4753-3p	CLIP-seq
MIRT2595313	hsa-miR-4760-3p	CLIP-seq
MIRT2595314	hsa-miR-4761-3p	CLIP-seq
MIRT2595315	hsa-miR-4768-5p	CLIP-seq
MIRT2070657	hsa-miR-4775	CLIP-seq
MIRT2595319	hsa-miR-488	CLIP-seq
MIRT2595320	hsa-miR-497	CLIP-seq
MIRT2595323	hsa-miR-513a-3p	CLIP-seq
MIRT2595324	hsa-miR-513a-5p	CLIP-seq
MIRT2595325	hsa-miR-513b	CLIP-seq
MIRT2595327	hsa-miR-520a-5p	CLIP-seq
MIRT2595328	hsa-miR-525-5p	CLIP-seq
MIRT2595330	hsa-miR-548g	CLIP-seq
MIRT2595332	hsa-miR-570	CLIP-seq
MIRT2595333	hsa-miR-579	CLIP-seq
MIRT2070658	hsa-miR-590-3p	CLIP-seq
MIRT2595334	hsa-miR-630	CLIP-seq
MIRT2595336	hsa-miR-670	CLIP-seq
MIRT2595338	hsa-miR-759	CLIP-seq
MIRT2595340	hsa-miR-892a	CLIP-seq
MIRT2595342	hsa-miR-934	CLIP-seq

Transcription factors

Show/Hide all(5)

Transcription factor	Regulation	Reference
CTNNB1	Activation	20442281
PGR	Unknown	21284604
RXRA	Unknown	17433303
TCF4	Activation	20442281
VDR	Unknown	17433303

Show/Hide all(32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0004630	Function	Phospholipase D activity	IEA
GO:0005515	Function	Protein binding	IPI	17853892, 18550814, 32814053
GO:0005765	Component	Lysosomal membrane	HDA	17897319
GO:0005768	Component	Endosome	IDA	14718562
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005794	Component	Golgi apparatus	IDA	14718562
GO:0005886	Component	Plasma membrane	TAS
GO:0006654	Process	Phosphatidic acid biosynthetic process	TAS
GO:0006935	Process	Chemotaxis	TAS
GO:0007264	Process	Small GTPase mediated signal transduction	TAS	8530346
GO:0007265	Process	Ras protein signal transduction	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016042	Process	Lipid catabolic process	IEA
GO:0016324	Component	Apical plasma membrane	IDA	22797597
GO:0030139	Component	Endocytic vesicle	IDA	22797597
GO:0031902	Component	Late endosome membrane	IEA
GO:0032534	Process	Regulation of microvillus assembly	IBA	21873635
GO:0032534	Process	Regulation of microvillus assembly	IMP	22797597
GO:0035091	Function	Phosphatidylinositol binding	IEA
GO:0035579	Component	Specific granule membrane	TAS
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0045727	Process	Positive regulation of translation	IMP	25361009
GO:0048017	Process	Inositol lipid-mediated signaling	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048870	Process	Cell motility	IBA	21873635
GO:0070290	Function	N-acylphosphatidylethanolamine-specific phospholipase D activity	IEA
GO:0070821	Component	Tertiary granule membrane	TAS
GO:0098693	Process	Regulation of synaptic vesicle cycle	IDA	11752468
GO:0098693	Process	Regulation of synaptic vesicle cycle	IMP	11752468
GO:0098981	Component	Cholinergic synapse	IDA	11752468
GO:0098981	Component	Cholinergic synapse	IMP	11752468

MIM	HGNC	e!Ensembl
602382	9067	ENSG00000075651

Protein

UniProt ID

Q13393

Protein name

Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)

Protein function

Function as phospholipase selective for phosphatidylcholine (PubMed:25936805, PubMed:8530346, PubMed:9582313). Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation o

PDB

6U8Z

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00787	PX	106 → 209	PX domain	Domain
PF00169	PH	220 → 328	PH domain	Domain
PF00614	PLDc	459 → 486	Phospholipase D Active site motif	Family
PF13091	PLDc_2	766 → 942	PLD-like domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. {ECO:0000269|PubMed:9582313}.

Sequence

MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL
KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ
AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT

Sequence length

1074

Interactions

View interactions

	KEGG		Reactome
	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways Ras signaling pathway cAMP signaling pathway Sphingolipid signaling pathway Phospholipase D signaling pathway Endocytosis Fc gamma R-mediated phagocytosis Glutamatergic synapse GnRH signaling pathway Parathyroid hormone synthesis, secretion and action Pathways in cancer Chemical carcinogenesis - reactive oxygen species Pancreatic cancer Choline metabolism in cancer		Synthesis of PA Role of phospholipids in phagocytosis Neutrophil degranulation

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Developmental cardiac valvular defect	Cardiac Valvular Defect, Developmental	rs769669104, rs778311238, rs1085307450	27799408
Hydrops fetalis	Hydrops Fetalis	rs28935477, rs1131691986
Mitral valve prolapse	Mitral Valve Prolapse Syndrome	rs768737101

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Renal Carcinoma	Renal Carcinoma	GWAS
Duodenal Ulcer	Duodenal Ulcer	GWAS

Show/Hide Text Mining Associations (52)

Disease Name	Relationship Type	References
Associations from Text Mining
Arrhythmogenic Right Ventricular Dysplasia	Associate	37770978
Astrocytoma	Associate	17640750
Breast Neoplasms	Associate	17726467, 23989060, 24556997, 33832505
Carcinogenesis	Associate	31673104
Carcinoma Hepatocellular	Associate	32904434, 33466191
Carcinoma Pancreatic Ductal	Stimulate	27713167
Carcinoma Pancreatic Ductal	Associate	37381714
Cardiomegaly	Associate	37770978
Cardiomyopathies	Associate	33645542, 37770978
Cell Transformation Neoplastic	Associate	21326806
Chromosome Aberrations	Associate	33142350
Colitis	Associate	36131027
Colorectal Neoplasms	Associate	36131027
Conotruncal cardiac defects	Associate	33142350
Drug Related Side Effects and Adverse Reactions	Associate	28654865
Endometrial Neoplasms	Associate	21228924
Fetal Death	Associate	37770978
Fetal Diseases	Associate	37770978
Glioblastoma	Associate	32074974
Heart Defects Congenital	Associate	33142350, 33645542
Heart Diseases	Associate	33645542, 37770978
Heart Failure	Associate	33645542
Histiocytosis Langerhans Cell	Associate	22949932
Hydrops Fetalis	Associate	37770978
Hypertension	Associate	27779208
Hypoxia	Associate	17640750
Leiomyosarcoma	Associate	21326806
Leukemia Myeloid Acute	Stimulate	32615908
Lymphoma Non Hodgkin	Associate	36362078
Melanoma	Associate	12839565
Neoplasm Invasiveness	Stimulate	27713167
Neoplasms	Associate	17726467, 21228924, 22279038, 25475140, 27713167, 29136407, 35775110, 36131027
Neoplasms	Inhibit	19478552
Nerve Degeneration	Associate	24632948
Obesity	Associate	28479334
Ovarian Neoplasms	Associate	36362078
Pancreatic Neoplasms	Associate	32537471, 37381714
Prostatic Hyperplasia	Stimulate	29136407
Prostatic Neoplasms	Associate	29136407
Prostatic Neoplasms Castration Resistant	Associate	29136407
Pulmonary Atresia	Associate	37770978
Right ventricle hypoplasia	Associate	37770978
Smooth Muscle Tumor	Associate	21326806
Squamous Cell Carcinoma of Head and Neck	Associate	31379206
Stomach Neoplasms	Associate	20625243, 26250158
Synovitis	Associate	29968759
Tricuspid Valve Insufficiency	Associate	37770978
Triple Negative Breast Neoplasms	Associate	17726467
Univentricular Heart	Associate	37770978
Uterine Cervical Neoplasms	Associate	35775110
Ventricular Fibrillation	Associate	37770978
Ventricular Outflow Obstruction Right	Associate	33142350

PLD1 (phospholipase D1)