BTBD1 (BTB domain containing 1)

Gene

• Entrez ID: 53339
• Gene name: BTB domain containing 1
• Gene symbol: BTBD1
• Synonyms (NCBI Gene): C15orf1, NS5ATP8
• Chromosome: 15
• Chromosome location: 15q25.2
• Summary: The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in prot

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052407	hsa-let-7a-5p	CLASH	23622248
MIRT538884	hsa-miR-137	PAR-CLIP	22012620
MIRT538883	hsa-miR-6783-5p	PAR-CLIP	22012620
MIRT538882	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT538881	hsa-miR-4795-5p	PAR-CLIP	22012620
MIRT538880	hsa-miR-4755-3p	PAR-CLIP	22012620
MIRT538879	hsa-miR-4471	PAR-CLIP	22012620
MIRT538878	hsa-miR-8059	PAR-CLIP	22012620
MIRT538877	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT538876	hsa-miR-3616-5p	PAR-CLIP	22012620
MIRT538875	hsa-miR-573	PAR-CLIP	22012620
MIRT538874	hsa-miR-1202	PAR-CLIP	22012620
MIRT538873	hsa-miR-3972	PAR-CLIP	22012620
MIRT538872	hsa-miR-5006-5p	PAR-CLIP	22012620
MIRT538871	hsa-miR-4482-3p	PAR-CLIP	22012620
MIRT441102	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT441101	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT441102	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT441101	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT728191	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT728189	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT728190	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT728188	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT728187	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT538884	hsa-miR-137	PAR-CLIP	22012620
MIRT538883	hsa-miR-6783-5p	PAR-CLIP	22012620
MIRT538882	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT538881	hsa-miR-4795-5p	PAR-CLIP	22012620
MIRT538880	hsa-miR-4755-3p	PAR-CLIP	22012620
MIRT538879	hsa-miR-4471	PAR-CLIP	22012620
MIRT538878	hsa-miR-8059	PAR-CLIP	22012620
MIRT538877	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT538876	hsa-miR-3616-5p	PAR-CLIP	22012620
MIRT538875	hsa-miR-573	PAR-CLIP	22012620
MIRT538874	hsa-miR-1202	PAR-CLIP	22012620
MIRT538873	hsa-miR-3972	PAR-CLIP	22012620
MIRT538872	hsa-miR-5006-5p	PAR-CLIP	22012620
MIRT538871	hsa-miR-4482-3p	PAR-CLIP	22012620
MIRT826264	hsa-miR-106a	CLIP-seq
MIRT826265	hsa-miR-106b	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826269	hsa-miR-1283	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT826271	hsa-miR-17	CLIP-seq
MIRT826272	hsa-miR-20a	CLIP-seq
MIRT826273	hsa-miR-20b	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT826277	hsa-miR-338-5p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826279	hsa-miR-3609	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT826282	hsa-miR-410	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT826285	hsa-miR-4661-5p	CLIP-seq
MIRT826286	hsa-miR-4684-5p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826289	hsa-miR-4724-3p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826291	hsa-miR-4796-3p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826294	hsa-miR-495	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT826297	hsa-miR-519d	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826299	hsa-miR-548ah	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT826305	hsa-miR-93	CLIP-seq
MIRT826306	hsa-miR-942	CLIP-seq
MIRT826307	hsa-miR-1257	CLIP-seq
MIRT826308	hsa-miR-1267	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT826310	hsa-miR-2113	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT826312	hsa-miR-224	CLIP-seq
MIRT826313	hsa-miR-23a	CLIP-seq
MIRT826314	hsa-miR-23b	CLIP-seq
MIRT826315	hsa-miR-23c	CLIP-seq
MIRT826316	hsa-miR-300	CLIP-seq
MIRT826317	hsa-miR-3074-3p	CLIP-seq
MIRT826318	hsa-miR-3123	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT826320	hsa-miR-3148	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT826322	hsa-miR-34b	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826326	hsa-miR-3611	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826329	hsa-miR-3647-5p	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT826331	hsa-miR-381	CLIP-seq
MIRT826332	hsa-miR-382	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826334	hsa-miR-409-3p	CLIP-seq
MIRT826335	hsa-miR-4277	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826342	hsa-miR-4666-3p	CLIP-seq
MIRT826343	hsa-miR-4668-5p	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826345	hsa-miR-4687-3p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT826349	hsa-miR-4768-5p	CLIP-seq
MIRT826350	hsa-miR-4778-5p	CLIP-seq
MIRT826351	hsa-miR-4789-5p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826353	hsa-miR-498	CLIP-seq
MIRT826354	hsa-miR-542-3p	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826355	hsa-miR-561	CLIP-seq
MIRT826356	hsa-miR-653	CLIP-seq
MIRT826357	hsa-miR-758	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT826264	hsa-miR-106a	CLIP-seq
MIRT826265	hsa-miR-106b	CLIP-seq
MIRT1944337	hsa-miR-124	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT826271	hsa-miR-17	CLIP-seq
MIRT826272	hsa-miR-20a	CLIP-seq
MIRT826273	hsa-miR-20b	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT826312	hsa-miR-224	CLIP-seq
MIRT1944338	hsa-miR-28-3p	CLIP-seq
MIRT1944339	hsa-miR-297	CLIP-seq
MIRT1944340	hsa-miR-298	CLIP-seq
MIRT1944341	hsa-miR-3117-5p	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT1944342	hsa-miR-3144-3p	CLIP-seq
MIRT1944343	hsa-miR-3149	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT1944344	hsa-miR-3171	CLIP-seq
MIRT1944345	hsa-miR-335	CLIP-seq
MIRT826277	hsa-miR-338-5p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826279	hsa-miR-3609	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT1944346	hsa-miR-3667-5p	CLIP-seq
MIRT1944347	hsa-miR-3686	CLIP-seq
MIRT1944348	hsa-miR-3714	CLIP-seq
MIRT1944349	hsa-miR-374a	CLIP-seq
MIRT1944350	hsa-miR-374b	CLIP-seq
MIRT1944351	hsa-miR-3910	CLIP-seq
MIRT826282	hsa-miR-410	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT1944352	hsa-miR-4477b	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT1944353	hsa-miR-4662a-5p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT1944354	hsa-miR-4704-5p	CLIP-seq
MIRT826289	hsa-miR-4724-3p	CLIP-seq
MIRT826291	hsa-miR-4796-3p	CLIP-seq
MIRT1944355	hsa-miR-4800-3p	CLIP-seq
MIRT1944356	hsa-miR-488	CLIP-seq
MIRT826353	hsa-miR-498	CLIP-seq
MIRT1944357	hsa-miR-506	CLIP-seq
MIRT1944358	hsa-miR-508-3p	CLIP-seq
MIRT826297	hsa-miR-519d	CLIP-seq
MIRT826299	hsa-miR-548ah	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT1944359	hsa-miR-769-5p	CLIP-seq
MIRT1944360	hsa-miR-875-5p	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826305	hsa-miR-93	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT2182913	hsa-miR-1245b-3p	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826307	hsa-miR-1257	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT826269	hsa-miR-1283	CLIP-seq
MIRT2182914	hsa-miR-135a	CLIP-seq
MIRT2182915	hsa-miR-135b	CLIP-seq
MIRT826309	hsa-miR-140-5p	CLIP-seq
MIRT2182916	hsa-miR-141	CLIP-seq
MIRT826270	hsa-miR-142-5p	CLIP-seq
MIRT2182917	hsa-miR-1827	CLIP-seq
MIRT2182918	hsa-miR-194	CLIP-seq
MIRT2182919	hsa-miR-200a	CLIP-seq
MIRT2182920	hsa-miR-204	CLIP-seq
MIRT2182921	hsa-miR-211	CLIP-seq
MIRT826310	hsa-miR-2113	CLIP-seq
MIRT826311	hsa-miR-214	CLIP-seq
MIRT2182922	hsa-miR-2278	CLIP-seq
MIRT826313	hsa-miR-23a	CLIP-seq
MIRT826314	hsa-miR-23b	CLIP-seq
MIRT826315	hsa-miR-23c	CLIP-seq
MIRT826317	hsa-miR-3074-3p	CLIP-seq
MIRT2182923	hsa-miR-30a	CLIP-seq
MIRT2182924	hsa-miR-30b	CLIP-seq
MIRT2182925	hsa-miR-30c	CLIP-seq
MIRT2182926	hsa-miR-30d	CLIP-seq
MIRT2182927	hsa-miR-30e	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826319	hsa-miR-3130-5p	CLIP-seq
MIRT826321	hsa-miR-3157-5p	CLIP-seq
MIRT2182928	hsa-miR-323-3p	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT1944345	hsa-miR-335	CLIP-seq
MIRT2182929	hsa-miR-337-3p	CLIP-seq
MIRT826278	hsa-miR-340	CLIP-seq
MIRT826323	hsa-miR-3545-5p	CLIP-seq
MIRT826324	hsa-miR-3591-5p	CLIP-seq
MIRT826325	hsa-miR-3606	CLIP-seq
MIRT826326	hsa-miR-3611	CLIP-seq
MIRT826327	hsa-miR-361-3p	CLIP-seq
MIRT826328	hsa-miR-3619-5p	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826329	hsa-miR-3647-5p	CLIP-seq
MIRT2182930	hsa-miR-3655	CLIP-seq
MIRT826330	hsa-miR-3657	CLIP-seq
MIRT826333	hsa-miR-3941	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT826334	hsa-miR-409-3p	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826335	hsa-miR-4277	CLIP-seq
MIRT826336	hsa-miR-4291	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT826337	hsa-miR-4460	CLIP-seq
MIRT826338	hsa-miR-4482	CLIP-seq
MIRT2182931	hsa-miR-4506	CLIP-seq
MIRT826339	hsa-miR-4519	CLIP-seq
MIRT2182932	hsa-miR-4637	CLIP-seq
MIRT2182933	hsa-miR-4646-3p	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826341	hsa-miR-466	CLIP-seq
MIRT826344	hsa-miR-4672	CLIP-seq
MIRT826286	hsa-miR-4684-5p	CLIP-seq
MIRT826345	hsa-miR-4687-3p	CLIP-seq
MIRT826346	hsa-miR-4691-3p	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826290	hsa-miR-4729	CLIP-seq
MIRT826347	hsa-miR-4731-3p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT1944355	hsa-miR-4800-3p	CLIP-seq
MIRT826352	hsa-miR-4801	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT2182934	hsa-miR-515-5p	CLIP-seq
MIRT2182935	hsa-miR-520d-5p	CLIP-seq
MIRT2182936	hsa-miR-524-5p	CLIP-seq
MIRT826354	hsa-miR-542-3p	CLIP-seq
MIRT826298	hsa-miR-548a-3p	CLIP-seq
MIRT826300	hsa-miR-548e	CLIP-seq
MIRT826301	hsa-miR-548f	CLIP-seq
MIRT826302	hsa-miR-548g	CLIP-seq
MIRT2182937	hsa-miR-556-3p	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2182938	hsa-miR-591	CLIP-seq
MIRT2182939	hsa-miR-604	CLIP-seq
MIRT2182940	hsa-miR-615-5p	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT2182941	hsa-miR-647	CLIP-seq
MIRT826356	hsa-miR-653	CLIP-seq
MIRT826357	hsa-miR-758	CLIP-seq
MIRT826358	hsa-miR-761	CLIP-seq
MIRT1944359	hsa-miR-769-5p	CLIP-seq
MIRT826359	hsa-miR-921	CLIP-seq
MIRT826360	hsa-miR-922	CLIP-seq
MIRT826306	hsa-miR-942	CLIP-seq
MIRT826266	hsa-miR-1237	CLIP-seq
MIRT826267	hsa-miR-1248	CLIP-seq
MIRT826280	hsa-miR-362-5p	CLIP-seq
MIRT826295	hsa-miR-500b	CLIP-seq
MIRT826296	hsa-miR-501-5p	CLIP-seq
MIRT2182914	hsa-miR-135a	CLIP-seq
MIRT2182915	hsa-miR-135b	CLIP-seq
MIRT2182920	hsa-miR-204	CLIP-seq
MIRT2182921	hsa-miR-211	CLIP-seq
MIRT2182930	hsa-miR-3655	CLIP-seq
MIRT2182933	hsa-miR-4646-3p	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2182939	hsa-miR-604	CLIP-seq
MIRT2182941	hsa-miR-647	CLIP-seq
MIRT2676074	hsa-miR-1229	CLIP-seq
MIRT1944337	hsa-miR-124	CLIP-seq
MIRT826268	hsa-miR-1279	CLIP-seq
MIRT1944340	hsa-miR-298	CLIP-seq
MIRT826274	hsa-miR-3128	CLIP-seq
MIRT826275	hsa-miR-326	CLIP-seq
MIRT826276	hsa-miR-330-5p	CLIP-seq
MIRT2676075	hsa-miR-3607-3p	CLIP-seq
MIRT2676076	hsa-miR-3659	CLIP-seq
MIRT1944347	hsa-miR-3686	CLIP-seq
MIRT1944348	hsa-miR-3714	CLIP-seq
MIRT1944351	hsa-miR-3910	CLIP-seq
MIRT826281	hsa-miR-3945	CLIP-seq
MIRT2676077	hsa-miR-409-5p	CLIP-seq
MIRT826283	hsa-miR-4253	CLIP-seq
MIRT826284	hsa-miR-4427	CLIP-seq
MIRT1944352	hsa-miR-4477b	CLIP-seq
MIRT2676078	hsa-miR-4641	CLIP-seq
MIRT826340	hsa-miR-4652-3p	CLIP-seq
MIRT826287	hsa-miR-4698	CLIP-seq
MIRT826288	hsa-miR-4720-5p	CLIP-seq
MIRT826348	hsa-miR-4753-3p	CLIP-seq
MIRT2676079	hsa-miR-4775	CLIP-seq
MIRT2676080	hsa-miR-4797-5p	CLIP-seq
MIRT826292	hsa-miR-4799-3p	CLIP-seq
MIRT826293	hsa-miR-487a	CLIP-seq
MIRT826294	hsa-miR-495	CLIP-seq
MIRT1944357	hsa-miR-506	CLIP-seq
MIRT826303	hsa-miR-578	CLIP-seq
MIRT2676081	hsa-miR-590-3p	CLIP-seq
MIRT826304	hsa-miR-635	CLIP-seq
MIRT2676082	hsa-miR-759	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IBA
GO:0000932	Component	P-body	IDA	12878161
GO:0000932	Component	P-body	IEA
GO:0005515	Function	Protein binding	IPI	12878161, 17543862, 18305892, 21145461, 22761572, 28514442, 32296183, 32814053, 33961781, 34591642, 37207277
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0007517	Process	Muscle organ development	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0022008	Process	Neurogenesis	IBA
GO:0030154	Process	Cell differentiation	IEA
GO:0032991	Component	Protein-containing complex	IDA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0043393	Process	Regulation of protein binding	NAS	11179693
GO:0097602	Function	Cullin family protein binding	IPI	14528312

Other IDs

• MIM: 608530
• HGNC: 1120
• e!Ensembl: ENSG00000064726

Protein

• UniProt ID: Q9H0C5
• Protein name: BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
• Protein function: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). Seems to regulate expression levels and/or subnuclear di
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	59 → 175	BTB/POZ domain	Domain
  PF07707	BACK	180 → 287	BTB And C-terminal Kelch	Domain
  PF08005	PHR	333 → 481	PHR domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous; highest levels in testes, heart and skeletal muscle. {ECO:0000269|PubMed:11179693, ECO:0000269|PubMed:11818025}.
• Sequence:

  MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFA
  FLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIE
  LPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNA
  FMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRL
  FGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREV
  VNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRIS
  IVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPN
  VCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIF
  YT

• Sequence length: 482

Pathways

Reactome:

Neddylation
Antigen processing: Ubiquitination & Proteasome degradation