Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	5230
Gene name	Phosphoglycerate kinase 1
Gene symbol	PGK1
Synonyms (NCBI Gene)	HEL-S-68pMIG10PGKA
Chromosome	X
Chromosome location	Xq21.1
Summary	The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cel

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SNP ID	Visualize variation	Clinical significance	Consequence
rs137852528	G>A	Pathogenic	Coding sequence variant, missense variant
rs137852529	G>A,C	Pathogenic	Coding sequence variant, missense variant
rs137852531	T>C	Pathogenic	Coding sequence variant, missense variant
rs137852532	G>T	Pathogenic	Coding sequence variant, missense variant
rs137852533	T>C	Pathogenic	Coding sequence variant, missense variant
rs137852534	T>C	Pathogenic-likely-pathogenic	Coding sequence variant, missense variant
rs137852535	A>T	Pathogenic	Coding sequence variant, missense variant
rs137852536	T>A	Pathogenic	Coding sequence variant, missense variant
rs137852537	G>A	Pathogenic	Coding sequence variant, missense variant
rs137852538	A>T	Pathogenic	Coding sequence variant, missense variant
rs137852539	A>C	Pathogenic	Coding sequence variant, missense variant
rs431905501	GTC>ATG	Pathogenic	Missense variant, coding sequence variant
rs431905502	AAG>-	Pathogenic	Inframe deletion, coding sequence variant
rs431905503	G>A	Pathogenic	Intron variant
rs782165735	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant
rs782667719	T>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant
rs797044505	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant
rs1057524140	G>A	Likely-pathogenic	Missense variant, coding sequence variant
rs1569550773	A>C	Likely-pathogenic	Coding sequence variant, missense variant

603

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050550	hsa-miR-20a-5p	CLASH	23622248
MIRT043151	hsa-miR-324-5p	CLASH	23622248
MIRT040970	hsa-miR-18a-3p	CLASH	23622248
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717329	hsa-miR-4286	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT622788	hsa-miR-1913	HITS-CLIP	19536157
MIRT622787	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT717326	hsa-miR-5699-5p	HITS-CLIP	19536157
MIRT717327	hsa-miR-4758-3p	HITS-CLIP	19536157
MIRT717325	hsa-miR-3189-5p	HITS-CLIP	19536157
MIRT717324	hsa-miR-6882-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622788	hsa-miR-1913	HITS-CLIP	23824327
MIRT622787	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT040970	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT176163	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT544141	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT329668	hsa-miR-548n	PAR-CLIP	21572407
MIRT329671	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT329669	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT544140	hsa-miR-6835-3p	PAR-CLIP	21572407
MIRT329670	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT544139	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT528397	hsa-miR-3133	PAR-CLIP	22012620
MIRT528396	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT176151	hsa-miR-141-3p	PAR-CLIP	22012620
MIRT176153	hsa-miR-200a-3p	PAR-CLIP	22012620
MIRT528395	hsa-miR-548b-3p	PAR-CLIP	22012620
MIRT528394	hsa-miR-4744	PAR-CLIP	22012620
MIRT528393	hsa-miR-570-3p	PAR-CLIP	22012620
MIRT528392	hsa-miR-610	PAR-CLIP	22012620
MIRT445734	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445733	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445732	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445731	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445730	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445729	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445728	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445726	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445727	hsa-miR-3646	PAR-CLIP	22100165
MIRT176177	hsa-miR-3185	PAR-CLIP	22100165
MIRT445725	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT439994	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT439994	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT726964	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT726963	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT733732	hsa-miR-6869-5p	Luciferase reporter assayqRT-PCRWestern blotting	32565733
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT717331	hsa-miR-181a-2-3p	HITS-CLIP	19536157
MIRT717330	hsa-miR-1273g-3p	HITS-CLIP	19536157
MIRT717329	hsa-miR-4286	HITS-CLIP	19536157
MIRT717328	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT622788	hsa-miR-1913	HITS-CLIP	19536157
MIRT622787	hsa-miR-324-3p	HITS-CLIP	19536157
MIRT717326	hsa-miR-5699-5p	HITS-CLIP	19536157
MIRT717327	hsa-miR-4758-3p	HITS-CLIP	19536157
MIRT717325	hsa-miR-3189-5p	HITS-CLIP	19536157
MIRT717324	hsa-miR-6882-3p	HITS-CLIP	19536157
MIRT717323	hsa-miR-4433a-5p	HITS-CLIP	19536157
MIRT717322	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT717321	hsa-miR-4433b-5p	HITS-CLIP	19536157
MIRT717320	hsa-miR-4646-3p	HITS-CLIP	19536157
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT622794	hsa-miR-6507-3p	HITS-CLIP	23824327
MIRT622793	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT622792	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT622791	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT622790	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT622789	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT622788	hsa-miR-1913	HITS-CLIP	23824327
MIRT622787	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT040970	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT622786	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT622785	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT622784	hsa-miR-4707-3p	HITS-CLIP	23824327
MIRT622783	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT622782	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT622781	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT622780	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT622779	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT176163	hsa-miR-548c-3p	PAR-CLIP	21572407
MIRT544141	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT329668	hsa-miR-548n	PAR-CLIP	21572407
MIRT329671	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT329669	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT544140	hsa-miR-6835-3p	PAR-CLIP	21572407
MIRT329670	hsa-miR-548at-5p	PAR-CLIP	21572407
MIRT544139	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT528397	hsa-miR-3133	PAR-CLIP	22012620
MIRT528396	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT176151	hsa-miR-141-3p	PAR-CLIP	22012620
MIRT176153	hsa-miR-200a-3p	PAR-CLIP	22012620
MIRT528395	hsa-miR-548b-3p	PAR-CLIP	22012620
MIRT528394	hsa-miR-4744	PAR-CLIP	22012620
MIRT528393	hsa-miR-570-3p	PAR-CLIP	22012620
MIRT528392	hsa-miR-610	PAR-CLIP	22012620
MIRT445734	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT445733	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT445732	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT445731	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT445730	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT445729	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT445728	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT445726	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT445727	hsa-miR-3646	PAR-CLIP	22100165
MIRT176177	hsa-miR-3185	PAR-CLIP	22100165
MIRT445725	hsa-miR-27b-5p	PAR-CLIP	22100165
MIRT756184	hsa-miR-346	Luciferase reporter assayWestern blottingqRT-PCRFlow cytometry	38091240
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT1227448	hsa-miR-1207-3p	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227465	hsa-miR-3606	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227468	hsa-miR-3668	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT1227470	hsa-miR-3924	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227476	hsa-miR-4504	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227483	hsa-miR-4663	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227493	hsa-miR-4728-3p	CLIP-seq
MIRT1227494	hsa-miR-4742-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227500	hsa-miR-494	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227506	hsa-miR-587	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT2066618	hsa-miR-3150a-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT2066619	hsa-miR-3175	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT2066620	hsa-miR-326	CLIP-seq
MIRT2066621	hsa-miR-330-5p	CLIP-seq
MIRT2066622	hsa-miR-3545-5p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT2066625	hsa-miR-4481	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2066626	hsa-miR-4667-5p	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT2066628	hsa-miR-4700-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT2066629	hsa-miR-4745-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT2066630	hsa-miR-4790-3p	CLIP-seq
MIRT2066631	hsa-miR-4796-3p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT2066632	hsa-miR-488	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227500	hsa-miR-494	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT2066634	hsa-miR-637	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2066635	hsa-miR-939	CLIP-seq
MIRT2294161	hsa-miR-103b	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227450	hsa-miR-1283	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2294162	hsa-miR-219-1-3p	CLIP-seq
MIRT2066618	hsa-miR-3150a-3p	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT2066619	hsa-miR-3175	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT2066620	hsa-miR-326	CLIP-seq
MIRT2066621	hsa-miR-330-5p	CLIP-seq
MIRT2294163	hsa-miR-335	CLIP-seq
MIRT2294164	hsa-miR-33a	CLIP-seq
MIRT2294165	hsa-miR-33b	CLIP-seq
MIRT2066622	hsa-miR-3545-5p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2294166	hsa-miR-376c	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066625	hsa-miR-4481	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2066626	hsa-miR-4667-5p	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227487	hsa-miR-4694-3p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT2066628	hsa-miR-4700-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT2066629	hsa-miR-4745-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT2066631	hsa-miR-4796-3p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT2066632	hsa-miR-488	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2294167	hsa-miR-548ae	CLIP-seq
MIRT2294168	hsa-miR-548aj	CLIP-seq
MIRT2294169	hsa-miR-548am	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT2294170	hsa-miR-548x	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066634	hsa-miR-637	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2066635	hsa-miR-939	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT2592145	hsa-miR-1323	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT2592146	hsa-miR-146a	CLIP-seq
MIRT2592147	hsa-miR-146b-5p	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT2592148	hsa-miR-3123	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2592149	hsa-miR-3714	CLIP-seq
MIRT2592150	hsa-miR-382	CLIP-seq
MIRT2592151	hsa-miR-3925-5p	CLIP-seq
MIRT2592152	hsa-miR-4278	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT2592153	hsa-miR-4311	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT2592154	hsa-miR-4523	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT2592155	hsa-miR-4639-5p	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2592156	hsa-miR-4675	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT2592157	hsa-miR-4688	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT2592158	hsa-miR-4741	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2592159	hsa-miR-499-3p	CLIP-seq
MIRT2592160	hsa-miR-499a-3p	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT2592161	hsa-miR-548an	CLIP-seq
MIRT2592162	hsa-miR-548o	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT2592163	hsa-miR-873	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2592164	hsa-miR-940	CLIP-seq
MIRT1227446	hsa-miR-105	CLIP-seq
MIRT1227447	hsa-miR-1178	CLIP-seq
MIRT2066616	hsa-miR-1270	CLIP-seq
MIRT1227449	hsa-miR-1273f	CLIP-seq
MIRT2592145	hsa-miR-1323	CLIP-seq
MIRT1227451	hsa-miR-1343	CLIP-seq
MIRT1227452	hsa-miR-141	CLIP-seq
MIRT1227453	hsa-miR-143	CLIP-seq
MIRT2592146	hsa-miR-146a	CLIP-seq
MIRT2592147	hsa-miR-146b-5p	CLIP-seq
MIRT1227454	hsa-miR-19a	CLIP-seq
MIRT1227455	hsa-miR-19b	CLIP-seq
MIRT1227456	hsa-miR-200a	CLIP-seq
MIRT1227457	hsa-miR-217	CLIP-seq
MIRT2066617	hsa-miR-298	CLIP-seq
MIRT1227458	hsa-miR-299-3p	CLIP-seq
MIRT1227459	hsa-miR-299-5p	CLIP-seq
MIRT1227460	hsa-miR-3121-3p	CLIP-seq
MIRT2592148	hsa-miR-3123	CLIP-seq
MIRT1227461	hsa-miR-3160-3p	CLIP-seq
MIRT1227462	hsa-miR-3187-3p	CLIP-seq
MIRT1227463	hsa-miR-3190	CLIP-seq
MIRT1227464	hsa-miR-3202	CLIP-seq
MIRT1227466	hsa-miR-3614-3p	CLIP-seq
MIRT2066623	hsa-miR-365	CLIP-seq
MIRT1227467	hsa-miR-3667-3p	CLIP-seq
MIRT1227469	hsa-miR-3671	CLIP-seq
MIRT2592149	hsa-miR-3714	CLIP-seq
MIRT2592150	hsa-miR-382	CLIP-seq
MIRT2592151	hsa-miR-3925-5p	CLIP-seq
MIRT2592152	hsa-miR-4278	CLIP-seq
MIRT1227471	hsa-miR-4297	CLIP-seq
MIRT2592153	hsa-miR-4311	CLIP-seq
MIRT1227472	hsa-miR-4435	CLIP-seq
MIRT1227473	hsa-miR-4477b	CLIP-seq
MIRT2066624	hsa-miR-4480	CLIP-seq
MIRT1227474	hsa-miR-4487	CLIP-seq
MIRT1227475	hsa-miR-4491	CLIP-seq
MIRT1227477	hsa-miR-450b-3p	CLIP-seq
MIRT1227478	hsa-miR-452	CLIP-seq
MIRT2592154	hsa-miR-4523	CLIP-seq
MIRT1227479	hsa-miR-4533	CLIP-seq
MIRT1227480	hsa-miR-4635	CLIP-seq
MIRT2592155	hsa-miR-4639-5p	CLIP-seq
MIRT1227481	hsa-miR-4657	CLIP-seq
MIRT1227482	hsa-miR-4661-5p	CLIP-seq
MIRT2592156	hsa-miR-4675	CLIP-seq
MIRT1227484	hsa-miR-4676-3p	CLIP-seq
MIRT2066627	hsa-miR-4683	CLIP-seq
MIRT1227485	hsa-miR-4685-5p	CLIP-seq
MIRT2592157	hsa-miR-4688	CLIP-seq
MIRT1227486	hsa-miR-4691-5p	CLIP-seq
MIRT1227488	hsa-miR-4699-5p	CLIP-seq
MIRT1227489	hsa-miR-4701-5p	CLIP-seq
MIRT1227490	hsa-miR-4708-5p	CLIP-seq
MIRT1227491	hsa-miR-4709-3p	CLIP-seq
MIRT1227492	hsa-miR-4713-3p	CLIP-seq
MIRT2592158	hsa-miR-4741	CLIP-seq
MIRT1227495	hsa-miR-4742-5p	CLIP-seq
MIRT1227496	hsa-miR-4770	CLIP-seq
MIRT1227497	hsa-miR-4795-5p	CLIP-seq
MIRT1227498	hsa-miR-4802-3p	CLIP-seq
MIRT1227499	hsa-miR-489	CLIP-seq
MIRT2592159	hsa-miR-499-3p	CLIP-seq
MIRT2592160	hsa-miR-499a-3p	CLIP-seq
MIRT1227501	hsa-miR-501-3p	CLIP-seq
MIRT1227502	hsa-miR-502-3p	CLIP-seq
MIRT2592161	hsa-miR-548an	CLIP-seq
MIRT2592162	hsa-miR-548o	CLIP-seq
MIRT1227503	hsa-miR-548s	CLIP-seq
MIRT1227504	hsa-miR-556-5p	CLIP-seq
MIRT1227505	hsa-miR-558	CLIP-seq
MIRT1227507	hsa-miR-588	CLIP-seq
MIRT1227508	hsa-miR-607	CLIP-seq
MIRT2066633	hsa-miR-620	CLIP-seq
MIRT1227509	hsa-miR-638	CLIP-seq
MIRT1227510	hsa-miR-767-3p	CLIP-seq
MIRT1227511	hsa-miR-769-3p	CLIP-seq
MIRT2592163	hsa-miR-873	CLIP-seq
MIRT1227512	hsa-miR-891b	CLIP-seq
MIRT2592164	hsa-miR-940	CLIP-seq

Show/Hide all (2)

Transcription factor	Regulation	Reference
HIF1A	Activation	8089148
MYC	Unknown	18809243

Show/Hide all (45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004618	Function	Phosphoglycerate kinase activity	EXP	1278465, 5009693
GO:0004618	Function	Phosphoglycerate kinase activity	IBA
GO:0004618	Function	Phosphoglycerate kinase activity	IEA
GO:0004618	Function	Phosphoglycerate kinase activity	IMP	7391028
GO:0004618	Function	Phosphoglycerate kinase activity	ISS
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	26942675
GO:0005515	Function	Protein binding	IPI	20392205, 20849852, 26030842, 26356530, 26942675, 28514442, 32707033, 33961781, 35271311
GO:0005524	Function	ATP binding	IBA
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	ISS
GO:0005615	Component	Extracellular space	IDA	11130727
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005759	Component	Mitochondrial matrix	IDA	26942675, 36849569
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	36849569
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006094	Process	Gluconeogenesis	IBA
GO:0006094	Process	Gluconeogenesis	IEA
GO:0006094	Process	Gluconeogenesis	TAS
GO:0006096	Process	Glycolytic process	IBA
GO:0006096	Process	Glycolytic process	IEA
GO:0006096	Process	Glycolytic process	IEA
GO:0006096	Process	Glycolytic process	IMP	7391028
GO:0016020	Component	Membrane	HDA	19946888
GO:0016301	Function	Kinase activity	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IMP	11130727
GO:0016740	Function	Transferase activity	IEA
GO:0030855	Process	Epithelial cell differentiation	IEP	21492153
GO:0031639	Process	Plasminogen activation	IMP	11130727
GO:0043531	Function	ADP binding	IBA
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0045121	Component	Membrane raft	IDA	25204797
GO:0046872	Function	Metal ion binding	IEA
GO:0047134	Function	Protein-disulfide reductase [NAD(P)H] activity	IMP	11130727
GO:0061621	Process	Canonical glycolysis	IEA
GO:0061621	Process	Canonical glycolysis	TAS
GO:0070062	Component	Extracellular exosome	HDA	11487543, 19199708, 20458337, 23533145
GO:0071456	Process	Cellular response to hypoxia	IDA	11130727
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0160218	Process	Negative regulation of pyruvate decarboxylation to acetyl-CoA	IDA	26942675

MIM	HGNC	e!Ensembl
311800	8896	ENSG00000102144

P00558

Protein name

Phosphoglycerate kinase 1 (EC 2.7.11.1) (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)

Protein function

Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed:30323285, PubMed:7391028). Both L- and D- forms of purine and pyrimidine nucleotides

PDB

2WZB , 2WZC , 2WZD , 2X13 , 2X14 , 2X15 , 2XE6 , 2XE7 , 2XE8 , 2Y3I , 2YBE , 2ZGV , 3C39 , 3C3A , 3C3B , 3C3C , 3ZOZ , 4AXX , 4O33 , 5M1R , 5M3U , 5M6Z , 5MXM , 5NP8 , 5O7D , 8YHP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00162	PGK	9 → 406	Phosphoglycerate kinase	Domain

Tissue specificity

TISSUE SPECIFICITY: Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men. {ECO:0000269|PubMed:26677959}.

Sequence

MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL
MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE
NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM
AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ
ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV
KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI

Sequence length

417

Interactions

View interactions

	KEGG		Reactome
	Glycolysis / Gluconeogenesis Metabolic pathways Carbon metabolism Biosynthesis of amino acids HIF-1 signaling pathway		Glycolysis Gluconeogenesis Manipulation of host energy metabolism

136

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Glycogen storage disease due to phosphoglycerate kinase 1 deficiency	Likely pathogenic; Pathogenic	rs2149132078, rs137852528, rs137852529, rs431905501, rs137852531, rs137852532, rs137852533, rs137852535, rs137852536, rs137852537, rs137852538, rs431905503, rs137852539	RCV002250801 RCV000010620 RCV000010621 RCV000010622 RCV000010624 RCV000010625 RCV000010626 RCV000010629 RCV000010630 RCV000010631 RCV000010632 RCV000010633 RCV000010634
Male infertility due to obstructive azoospermia	Likely pathogenic	rs1569550773	RCV000767230

Show/Hide Unknown Diseases (13)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Epilepsy	Benign; Likely benign	rs143031509	RCV005626743
Epileptic encephalopathy	Uncertain significance	rs1060499671	RCV000449521
Familial cancer of breast	Likely benign; Benign	rs138345294, rs370410785, rs78165041	RCV005916022 RCV005932058 RCV005904816
Hereditary skeletal muscle disorder	Conflicting classifications of pathogenicity	rs202138276	RCV005626448
Intellectual disability	Uncertain significance	rs1557247562	RCV005626805
Lung cancer	Likely benign	rs138345294	RCV005916023
Malignant lymphoma, large B-cell, diffuse	Benign	rs2073178, rs2073177	RCV005902167 RCV005902165
Optic atrophy	Likely benign	rs781845619	RCV004817068
PGK1-related disorder	Uncertain significance; Conflicting classifications of pathogenicity; Benign; Likely benign	rs2078363321, rs148399096, rs782751239, rs143031509, rs187714418, rs150956842, rs782807093, rs431905502, rs1045428290, rs2078363408, rs2522502101, rs782014533, rs782668224, rs781839243, rs146350576, rs142525614 View all (1 more)	RCV001825179 RCV004548251 RCV004550363 RCV004550404 RCV004548311 RCV004548326 RCV004738593 RCV004724732 RCV004548658 RCV004550733 RCV004550697 RCV004548741 RCV004550067 RCV004551714 RCV004553510 RCV004553511
Phosphoglycerate kinase electrophoretic variant PGK II	other	rs137852530	RCV000010623
Profound global developmental delay	Uncertain significance	rs1060499671	RCV000449521
Uterine corpus endometrial carcinoma	Likely benign	rs138345294, rs150219676	RCV005916024 RCV005917804
Uveal melanoma	Benign	rs2073178, rs2073177	RCV005902166 RCV005902164

Show/Hide Text Mining Associations (82)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	14573703, 34814273
Adenocarcinoma	Stimulate	27150162
Adenocarcinoma of Lung	Associate	14573703
Altitude Sickness	Associate	33393624
Anemia Hemolytic	Associate	16412025, 39787833
Astrocytoma	Associate	22742733
Bone Diseases Metabolic	Associate	22619369
Bone Marrow Diseases	Associate	24376734
Brain Diseases Metabolic Inborn	Associate	39787833
Breast Neoplasms	Associate	16048908, 30537744, 31578148, 32028979, 32070368, 33597614, 34600547, 34790279, 34868337, 35441810, 36077333, 36860848, 37190091, 37986376, 39192221, 39684297 View all (1 more)
Breast Neoplasms	Stimulate	25867275, 36388159
Carcinogenesis	Associate	32489020, 39456901, 39684297
Carcinoma Adenoid Cystic	Associate	37741973
Carcinoma Hepatocellular	Associate	19200351, 28749413
Carcinoma Pancreatic Ductal	Associate	32241274, 38098044
Carcinoma Renal Cell	Associate	33564363
Carcinosarcoma	Associate	32439920
Cataract	Associate	34055996
Cataract Age Related Nuclear	Associate	34055996
Cell Transformation Neoplastic	Associate	38098044
Chordoma	Associate	38282590
Chronic Disease	Associate	34975312
Cleft palate X linked	Associate	1570839
Colonic Neoplasms	Associate	18603805
Death	Associate	32241274
Developmental Disabilities	Associate	16740138
Diabetes Mellitus	Associate	19582723
Dystonia 3 Torsion X Linked	Associate	1550125
Ectodermal Dysplasia	Associate	1357963
Ectodermal Dysplasia 1 Anhidrotic	Associate	3163892
Endometrial Neoplasms	Associate	32439920
Esophageal Squamous Cell Carcinoma	Associate	36966136
Fatigue	Associate	16740138
Gallbladder Neoplasms	Inhibit	26656369
Gastrointestinal Diseases	Associate	35008842
Glioblastoma	Associate	37408007
Glioma	Associate	32565733
Hemophilia A	Associate	34445777
Hypoxia	Associate	27625398, 33941139
Hypoxia	Stimulate	27765905, 36230969
Hypoxia Brain	Associate	32593213, 37408007
Immunologic Deficiency Syndromes	Associate	39787833
Lung Diseases	Associate	27625398
Lymphoma	Associate	20037605
Metabolism Inborn Errors	Associate	16412025
Metabolism Inborn Errors	Inhibit	39787833
Muscle Weakness	Associate	39787833
Muscular Diseases	Associate	20151463, 22348148, 31658606
Necrosis	Associate	31767834
Neoplasm Metastasis	Associate	28749413, 29954422, 32028979, 39192221
Neoplasm Metastasis	Stimulate	30537744, 39315723
Neoplasms	Associate	18401453, 19582723, 19688824, 23684136, 24376734, 25734817, 28749413, 29995887, 31578148, 32070368, 34668665, 34790279, 35502531, 38098044, 39315723, 39456901, 39684297 View all (2 more)
Neoplasms	Stimulate	30537744
Neoplasms	Inhibit	37408007
Neoplasms Squamous Cell	Associate	14573703
Neuroblastoma	Associate	24376734, 27765905
Neuroendocrine Tumors	Associate	34712204
Neurologic Manifestations	Associate	16412025, 16740138, 39787833
Neuromuscular Diseases	Associate	39787833
Obesity	Associate	37894825
Osteoarthritis	Associate	22619369
Osteopenic Nonfracture Syndrome	Associate	22619369
Ovarian Neoplasms	Associate	25096996
Pancreatic Neoplasms	Associate	19582723, 36807568
Pancreatitis Chronic	Associate	19582723
Peritoneal Neoplasms	Stimulate	19688824
Peritonitis	Associate	19688824
Phosphoglycerate Kinase 1 Deficiency	Associate	16412025, 16740138, 20151463, 22348148, 31658606
Precancerous Conditions	Associate	34790279
Prostatic Neoplasms	Associate	19893039, 22805767, 29954422, 37894825
Pulmonary Arterial Hypertension	Stimulate	35960497
Rhegmatogenous Retinal Detachment Autosomal Dominant	Associate	29641463
Seizures	Associate	16740138
Severe Combined Immunodeficiency	Associate	2565084, 8317482
Squamous Cell Carcinoma of Head and Neck	Associate	33941139, 34599215, 34668665, 38035710, 38256104, 39456901
Squamous Intraepithelial Lesions	Associate	16436642
Stomach Neoplasms	Associate	19688824, 31578148, 36684675
Triple Negative Breast Neoplasms	Associate	32350346, 36077333, 40634657
Triple Negative Breast Neoplasms	Stimulate	37190091
Urethral Neoplasms	Associate	36292976
Urinary Bladder Neoplasms	Stimulate	39315723
X Linked Combined Immunodeficiency Diseases	Associate	2565084

PGK1 (phosphoglycerate kinase 1)