PGGT1B (protein geranylgeranyltransferase type I subunit beta)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5229 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Protein geranylgeranyltransferase type I subunit beta |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PGGT1B |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BGGI, GGTI |
Chromosome
Chromosome number
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5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which `A` is an aliphatic amino acid and `X` is leucine (summarized by Zhang et al., 1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | P53609 | |||||||||||||||||||||||||
Protein name | Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) | |||||||||||||||||||||||||
Protein function | Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, R | |||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 377 | |||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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