Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
522
Gene name Gene Name - the full gene name approved by the HGNC.
ATP synthase peripheral stalk subunit F6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ATP5PF
Synonyms (NCBI Gene) Gene synonyms aliases
ATP5, ATP5A, ATP5J, ATPM, CF6, F6
Chromosome Chromosome number
21
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
21q21.3
Summary Summary of gene provided in NCBI Entrez Gene.
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000276 Component Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) IEA
GO:0005515 Function Protein binding IPI 27499296, 30021884, 32296183
GO:0005739 Component Mitochondrion HDA 20833797
GO:0005739 Component Mitochondrion IDA
GO:0005743 Component Mitochondrial inner membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603152 847 ENSG00000154723
Protein
UniProt ID P18859
Protein name ATP synthase peripheral stalk subunit F6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6)
Protein function Subunit F6, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the res
PDB 8H9G , 8H9K , 8H9N , 8H9R , 8H9S , 8H9T , 8H9U , 8H9V , 8KI3
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05511 ATP-synt_F6 1 97 Mitochondrial ATP synthase coupling factor 6 Family
Sequence
Sequence length 108
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Oxidative phosphorylation
Metabolic pathways
Thermogenesis
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy
  Formation of ATP by chemiosmotic coupling
Cristae formation