SYT17 (synaptotagmin 17)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
51760
Gene name Gene Name - the full gene name approved by the HGNC.
Synaptotagmin 17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SYT17
Synonyms (NCBI Gene) Gene synonyms aliases
Syt-17, sytXVII
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p12.3
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(227)
miRTarBase ID miRNA Experiments Reference
MIRT018929 hsa-miR-335-5p Microarray 18185580
MIRT607313 hsa-miR-8485 HITS-CLIP 22927820
MIRT663407 hsa-miR-329-3p HITS-CLIP 22927820
MIRT663406 hsa-miR-362-3p HITS-CLIP 22927820
MIRT607312 hsa-miR-603 HITS-CLIP 22927820
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(18)
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA
GO:0005515 Function Protein binding IPI 16189514, 16730941, 25416956, 28514442, 31515488, 32296183
GO:0005544 Function Calcium-dependent phospholipid binding IBA
GO:0005802 Component Trans-Golgi network IEA
GO:0005886 Component Plasma membrane IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9BSW7
Protein name Synaptotagmin-17 (Protein B/K) (Synaptotagmin XVII) (SytXVII)
Protein function Plays a role in dendrite formation by melanocytes (PubMed:23999003).
PDB 2ENP
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2 199 → 312 C2 domain Domain
PF00168 C2 336 → 443 C2 domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra, and pituitary), kidney, and prostate. Expressed in fetal brain, kidney and lung (PubMed:16672768). Expressed in melanocyt
Sequence 
MAYIQLEPLNEGFLSRISGLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPW
LMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSP
LIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEIL
SKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQK
NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEV
DLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF
VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND
FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT
Sequence length 474
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Parkinson Disease Parkinson's disease N/A N/A GWAS
Show/Hide Text Mining Associations (2)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Autoimmune Diseases of the Nervous System Stimulate 32369831
Neoplasms Associate 34127544