Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51725
Gene name Gene Name - the full gene name approved by the HGNC.	F-box protein 40
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FBXO40
Synonyms (NCBI Gene) Gene synonyms aliases	FBX40
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q13.33
Summary Summary of gene provided in NCBI Entrez Gene.	Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box pr

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miRTarBase ID	miRNA	Experiments	Reference
MIRT489012	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT489011	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT489010	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT489009	hsa-miR-5192	PAR-CLIP	23592263
MIRT489008	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT489007	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT489005	hsa-miR-3652	PAR-CLIP	23592263
MIRT489006	hsa-miR-4430	PAR-CLIP	23592263
MIRT489004	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT489003	hsa-miR-8085	PAR-CLIP	23592263
MIRT489002	hsa-miR-3175	PAR-CLIP	23592263
MIRT489001	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT489000	hsa-miR-5698	PAR-CLIP	23592263
MIRT488999	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT488998	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT488996	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT446592	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446590	hsa-miR-4725-5p	PAR-CLIP	22100165
MIRT446589	hsa-miR-3942-3p	PAR-CLIP	22100165
MIRT446588	hsa-miR-30a-3p	PAR-CLIP	22100165
MIRT446587	hsa-miR-30d-3p	PAR-CLIP	22100165
MIRT446586	hsa-miR-30e-3p	PAR-CLIP	22100165
MIRT446592	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446590	hsa-miR-4725-5p	PAR-CLIP	22100165
MIRT446589	hsa-miR-3942-3p	PAR-CLIP	22100165
MIRT446588	hsa-miR-30a-3p	PAR-CLIP	22100165
MIRT446587	hsa-miR-30d-3p	PAR-CLIP	22100165
MIRT446586	hsa-miR-30e-3p	PAR-CLIP	22100165
MIRT489012	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT489011	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT489010	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT489009	hsa-miR-5192	PAR-CLIP	23592263
MIRT489008	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT489007	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT489005	hsa-miR-3652	PAR-CLIP	23592263
MIRT489006	hsa-miR-4430	PAR-CLIP	23592263
MIRT489004	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT489003	hsa-miR-8085	PAR-CLIP	23592263
MIRT489002	hsa-miR-3175	PAR-CLIP	23592263
MIRT489001	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT489000	hsa-miR-5698	PAR-CLIP	23592263
MIRT488999	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT488998	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT488996	hsa-miR-6515-5p	PAR-CLIP	23592263
MIRT446592	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446590	hsa-miR-4725-5p	PAR-CLIP	22100165
MIRT446589	hsa-miR-3942-3p	PAR-CLIP	22100165
MIRT446588	hsa-miR-30a-3p	PAR-CLIP	22100165
MIRT446587	hsa-miR-30d-3p	PAR-CLIP	22100165
MIRT446586	hsa-miR-30e-3p	PAR-CLIP	22100165
MIRT446592	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446590	hsa-miR-4725-5p	PAR-CLIP	22100165
MIRT446589	hsa-miR-3942-3p	PAR-CLIP	22100165
MIRT446588	hsa-miR-30a-3p	PAR-CLIP	22100165
MIRT446587	hsa-miR-30d-3p	PAR-CLIP	22100165
MIRT446586	hsa-miR-30e-3p	PAR-CLIP	22100165
MIRT992311	hsa-miR-1256	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992314	hsa-miR-1915	CLIP-seq
MIRT992315	hsa-miR-204	CLIP-seq
MIRT992316	hsa-miR-211	CLIP-seq
MIRT992317	hsa-miR-23a	CLIP-seq
MIRT992318	hsa-miR-23b	CLIP-seq
MIRT992319	hsa-miR-23c	CLIP-seq
MIRT992320	hsa-miR-30a	CLIP-seq
MIRT992321	hsa-miR-30b	CLIP-seq
MIRT992322	hsa-miR-30c	CLIP-seq
MIRT992323	hsa-miR-30d	CLIP-seq
MIRT992324	hsa-miR-30e	CLIP-seq
MIRT992325	hsa-miR-3155	CLIP-seq
MIRT992326	hsa-miR-3155b	CLIP-seq
MIRT992327	hsa-miR-3157-5p	CLIP-seq
MIRT992328	hsa-miR-3183	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT992330	hsa-miR-3202	CLIP-seq
MIRT992331	hsa-miR-3591-5p	CLIP-seq
MIRT992332	hsa-miR-3607-3p	CLIP-seq
MIRT992333	hsa-miR-3667-5p	CLIP-seq
MIRT992334	hsa-miR-3672	CLIP-seq
MIRT992335	hsa-miR-3918	CLIP-seq
MIRT992336	hsa-miR-3922-5p	CLIP-seq
MIRT992337	hsa-miR-3929	CLIP-seq
MIRT992338	hsa-miR-4280	CLIP-seq
MIRT992339	hsa-miR-4283	CLIP-seq
MIRT992340	hsa-miR-4293	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT992342	hsa-miR-4330	CLIP-seq
MIRT992343	hsa-miR-4419b	CLIP-seq
MIRT992344	hsa-miR-4446-5p	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT992346	hsa-miR-4461	CLIP-seq
MIRT992347	hsa-miR-4478	CLIP-seq
MIRT992348	hsa-miR-4493	CLIP-seq
MIRT992349	hsa-miR-4533	CLIP-seq
MIRT992350	hsa-miR-4537	CLIP-seq
MIRT992351	hsa-miR-4642	CLIP-seq
MIRT992352	hsa-miR-4649-3p	CLIP-seq
MIRT992353	hsa-miR-4659a-3p	CLIP-seq
MIRT992354	hsa-miR-4659a-5p	CLIP-seq
MIRT992355	hsa-miR-4659b-3p	CLIP-seq
MIRT992356	hsa-miR-4659b-5p	CLIP-seq
MIRT992357	hsa-miR-4685-5p	CLIP-seq
MIRT992358	hsa-miR-4691-3p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992360	hsa-miR-4717-3p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992362	hsa-miR-4723-3p	CLIP-seq
MIRT992363	hsa-miR-4727-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT992365	hsa-miR-4753-5p	CLIP-seq
MIRT992366	hsa-miR-4755-5p	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT992368	hsa-miR-4769-3p	CLIP-seq
MIRT992369	hsa-miR-4786-5p	CLIP-seq
MIRT992370	hsa-miR-4796-5p	CLIP-seq
MIRT992371	hsa-miR-484	CLIP-seq
MIRT992372	hsa-miR-485-5p	CLIP-seq
MIRT992373	hsa-miR-515-5p	CLIP-seq
MIRT992374	hsa-miR-519a	CLIP-seq
MIRT992375	hsa-miR-519b-3p	CLIP-seq
MIRT992376	hsa-miR-519c-3p	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992379	hsa-miR-623	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992384	hsa-miR-769-5p	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq
MIRT992386	hsa-miR-942	CLIP-seq
MIRT1994290	hsa-miR-1228	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT1994291	hsa-miR-136	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT992330	hsa-miR-3202	CLIP-seq
MIRT1994292	hsa-miR-3622a-3p	CLIP-seq
MIRT1994293	hsa-miR-3622b-3p	CLIP-seq
MIRT992334	hsa-miR-3672	CLIP-seq
MIRT992337	hsa-miR-3929	CLIP-seq
MIRT1994294	hsa-miR-4292	CLIP-seq
MIRT992340	hsa-miR-4293	CLIP-seq
MIRT1994295	hsa-miR-4308	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT992343	hsa-miR-4419b	CLIP-seq
MIRT1994296	hsa-miR-4434	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT1994297	hsa-miR-4469	CLIP-seq
MIRT992347	hsa-miR-4478	CLIP-seq
MIRT992348	hsa-miR-4493	CLIP-seq
MIRT1994298	hsa-miR-4516	CLIP-seq
MIRT1994299	hsa-miR-4531	CLIP-seq
MIRT992349	hsa-miR-4533	CLIP-seq
MIRT992352	hsa-miR-4649-3p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT992365	hsa-miR-4753-5p	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT992369	hsa-miR-4786-5p	CLIP-seq
MIRT1994300	hsa-miR-4802-3p	CLIP-seq
MIRT992372	hsa-miR-485-5p	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992384	hsa-miR-769-5p	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT1994292	hsa-miR-3622a-3p	CLIP-seq
MIRT1994293	hsa-miR-3622b-3p	CLIP-seq
MIRT992334	hsa-miR-3672	CLIP-seq
MIRT992337	hsa-miR-3929	CLIP-seq
MIRT992340	hsa-miR-4293	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT992343	hsa-miR-4419b	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT992347	hsa-miR-4478	CLIP-seq
MIRT992348	hsa-miR-4493	CLIP-seq
MIRT992350	hsa-miR-4537	CLIP-seq
MIRT992352	hsa-miR-4649-3p	CLIP-seq
MIRT2228329	hsa-miR-4649-5p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT992365	hsa-miR-4753-5p	CLIP-seq
MIRT2228330	hsa-miR-4767	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT992369	hsa-miR-4786-5p	CLIP-seq
MIRT2228331	hsa-miR-4792	CLIP-seq
MIRT992372	hsa-miR-485-5p	CLIP-seq
MIRT992374	hsa-miR-519a	CLIP-seq
MIRT992375	hsa-miR-519b-3p	CLIP-seq
MIRT992376	hsa-miR-519c-3p	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992384	hsa-miR-769-5p	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq
MIRT992374	hsa-miR-519a	CLIP-seq
MIRT992375	hsa-miR-519b-3p	CLIP-seq
MIRT992376	hsa-miR-519c-3p	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT2449519	hsa-miR-4662a-5p	CLIP-seq
MIRT2449520	hsa-miR-4676-5p	CLIP-seq
MIRT2449521	hsa-miR-4684-5p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT2449522	hsa-miR-4755-3p	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT2449523	hsa-miR-575	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT1994296	hsa-miR-4434	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT1994298	hsa-miR-4516	CLIP-seq
MIRT1994299	hsa-miR-4531	CLIP-seq
MIRT992350	hsa-miR-4537	CLIP-seq
MIRT2449519	hsa-miR-4662a-5p	CLIP-seq
MIRT2449520	hsa-miR-4676-5p	CLIP-seq
MIRT2449521	hsa-miR-4684-5p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT2449522	hsa-miR-4755-3p	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT2228331	hsa-miR-4792	CLIP-seq
MIRT1994300	hsa-miR-4802-3p	CLIP-seq
MIRT2449523	hsa-miR-575	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq
MIRT992312	hsa-miR-1285	CLIP-seq
MIRT992313	hsa-miR-1827	CLIP-seq
MIRT992329	hsa-miR-3187-5p	CLIP-seq
MIRT992341	hsa-miR-4317	CLIP-seq
MIRT992345	hsa-miR-4459	CLIP-seq
MIRT2449519	hsa-miR-4662a-5p	CLIP-seq
MIRT2449520	hsa-miR-4676-5p	CLIP-seq
MIRT2449521	hsa-miR-4684-5p	CLIP-seq
MIRT992359	hsa-miR-4695-5p	CLIP-seq
MIRT992361	hsa-miR-4722-5p	CLIP-seq
MIRT992364	hsa-miR-4746-3p	CLIP-seq
MIRT2449522	hsa-miR-4755-3p	CLIP-seq
MIRT992367	hsa-miR-4768-3p	CLIP-seq
MIRT2228331	hsa-miR-4792	CLIP-seq
MIRT2449523	hsa-miR-575	CLIP-seq
MIRT992377	hsa-miR-612	CLIP-seq
MIRT992378	hsa-miR-616	CLIP-seq
MIRT992380	hsa-miR-658	CLIP-seq
MIRT992381	hsa-miR-661	CLIP-seq
MIRT992382	hsa-miR-665	CLIP-seq
MIRT992383	hsa-miR-766	CLIP-seq
MIRT992385	hsa-miR-940	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	TAS
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0008270	Function	Zinc ion binding	IEA
GO:0042692	Process	Muscle cell differentiation	ISS	17928169
GO:0043687	Process	Post-translational protein modification	TAS
GO:0061630	Function	Ubiquitin protein ligase activity	IEA

MIM	HGNC	e!Ensembl
609107	29816	ENSG00000163833

Protein

UniProt ID

Q9UH90

Protein name

F-box only protein 40 (Muscle disease-related protein)

Protein function

Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15965	zf-TRAF_2	12 → 104	TRAF-like zinc-finger	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed only in heart and skeletal muscle. {ECO:0000269|PubMed:17928169}.

Sequence

MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPL
EQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETP
SEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGL
VPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCES
KNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKT
AVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKR
ARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSID
GLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCN
KFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQEL
KTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVS
VLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSM
SEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS

Sequence length

709

Interactions

View interactions

	Reactome
			Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Autism	Autistic Disorder	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699 View all (8 more)	19404257

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Autistic Disorder	Associate	19404257

FBXO40 (F-box protein 40)