Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51655
Gene name Gene Name - the full gene name approved by the HGNC.	Ras related dexamethasone induced 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RASD1
Synonyms (NCBI Gene) Gene synonyms aliases	AGS1, DEXRAS1, MGC:26290
Disease Acronyms (UniProt) Disease acronyms from UniProt database	AGS1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with

Show/Hide all(253)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004439	hsa-miR-375	Luciferase reporter assay, Microarray, qRT-PCR	20978187
MIRT018256	hsa-miR-335-5p	Microarray	18185580
MIRT492476	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT492475	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT492472	hsa-miR-3175	PAR-CLIP	20371350
MIRT492470	hsa-miR-3180	PAR-CLIP	20371350
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT492468	hsa-miR-3196	PAR-CLIP	20371350
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	20371350
MIRT492465	hsa-miR-4488	PAR-CLIP	20371350
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	20371350
MIRT492476	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT492475	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT492472	hsa-miR-3175	PAR-CLIP	20371350
MIRT492470	hsa-miR-3180	PAR-CLIP	20371350
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT492468	hsa-miR-3196	PAR-CLIP	20371350
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	20371350
MIRT492465	hsa-miR-4488	PAR-CLIP	20371350
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	20371350
MIRT492476	hsa-miR-139-3p	PAR-CLIP	23592263
MIRT492475	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT492472	hsa-miR-3175	PAR-CLIP	23592263
MIRT492470	hsa-miR-3180	PAR-CLIP	23592263
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT492468	hsa-miR-3196	PAR-CLIP	23592263
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	23592263
MIRT492465	hsa-miR-4488	PAR-CLIP	23592263
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	23592263
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	26701625
MIRT492475	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT492475	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT492475	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT492475	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT492475	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT492472	hsa-miR-3175	PAR-CLIP	26701625
MIRT492472	hsa-miR-3175	PAR-CLIP	26701625
MIRT492472	hsa-miR-3175	PAR-CLIP	26701625
MIRT492472	hsa-miR-3175	PAR-CLIP	26701625
MIRT492472	hsa-miR-3175	PAR-CLIP	26701625
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT492470	hsa-miR-3180	PAR-CLIP	26701625
MIRT492470	hsa-miR-3180	PAR-CLIP	26701625
MIRT492470	hsa-miR-3180	PAR-CLIP	26701625
MIRT492470	hsa-miR-3180	PAR-CLIP	26701625
MIRT492470	hsa-miR-3180	PAR-CLIP	26701625
MIRT492468	hsa-miR-3196	PAR-CLIP	26701625
MIRT492468	hsa-miR-3196	PAR-CLIP	26701625
MIRT492468	hsa-miR-3196	PAR-CLIP	26701625
MIRT492468	hsa-miR-3196	PAR-CLIP	26701625
MIRT492468	hsa-miR-3196	PAR-CLIP	26701625
MIRT492465	hsa-miR-4488	PAR-CLIP	26701625
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	26701625
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT492476	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT492475	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT492472	hsa-miR-3175	PAR-CLIP	20371350
MIRT492470	hsa-miR-3180	PAR-CLIP	20371350
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT492468	hsa-miR-3196	PAR-CLIP	20371350
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	20371350
MIRT492465	hsa-miR-4488	PAR-CLIP	20371350
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	20371350
MIRT492476	hsa-miR-139-3p	PAR-CLIP	20371350
MIRT492475	hsa-miR-149-3p	PAR-CLIP	20371350
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	20371350
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	20371350
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	20371350
MIRT492472	hsa-miR-3175	PAR-CLIP	20371350
MIRT492470	hsa-miR-3180	PAR-CLIP	20371350
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT492468	hsa-miR-3196	PAR-CLIP	20371350
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	20371350
MIRT492465	hsa-miR-4488	PAR-CLIP	20371350
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	20371350
MIRT492476	hsa-miR-139-3p	PAR-CLIP	23592263
MIRT492475	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT492474	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT492473	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT492471	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT492472	hsa-miR-3175	PAR-CLIP	23592263
MIRT492470	hsa-miR-3180	PAR-CLIP	23592263
MIRT492469	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT492468	hsa-miR-3196	PAR-CLIP	23592263
MIRT492467	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT492466	hsa-miR-1237-5p	PAR-CLIP	23592263
MIRT492465	hsa-miR-4488	PAR-CLIP	23592263
MIRT492464	hsa-miR-4697-5p	PAR-CLIP	23592263
MIRT1292104	hsa-miR-106a	CLIP-seq
MIRT1292105	hsa-miR-106b	CLIP-seq
MIRT1292106	hsa-miR-130a	CLIP-seq
MIRT1292107	hsa-miR-130b	CLIP-seq
MIRT1292108	hsa-miR-17	CLIP-seq
MIRT1292109	hsa-miR-1908	CLIP-seq
MIRT1292110	hsa-miR-2052	CLIP-seq
MIRT1292111	hsa-miR-20a	CLIP-seq
MIRT1292112	hsa-miR-20b	CLIP-seq
MIRT1292113	hsa-miR-2113	CLIP-seq
MIRT1292114	hsa-miR-224	CLIP-seq
MIRT1292115	hsa-miR-2467-3p	CLIP-seq
MIRT1292116	hsa-miR-2467-5p	CLIP-seq
MIRT1292117	hsa-miR-301a	CLIP-seq
MIRT1292118	hsa-miR-301b	CLIP-seq
MIRT1292119	hsa-miR-30a	CLIP-seq
MIRT1292120	hsa-miR-30b	CLIP-seq
MIRT1292121	hsa-miR-30c	CLIP-seq
MIRT1292122	hsa-miR-30d	CLIP-seq
MIRT1292123	hsa-miR-30e	CLIP-seq
MIRT1292124	hsa-miR-3121-5p	CLIP-seq
MIRT1292125	hsa-miR-3122	CLIP-seq
MIRT1292126	hsa-miR-3609	CLIP-seq
MIRT1292127	hsa-miR-3614-5p	CLIP-seq
MIRT1292128	hsa-miR-3616-3p	CLIP-seq
MIRT1292129	hsa-miR-3666	CLIP-seq
MIRT1292130	hsa-miR-3689a-3p	CLIP-seq
MIRT1292131	hsa-miR-3689c	CLIP-seq
MIRT1292132	hsa-miR-3913-5p	CLIP-seq
MIRT1292133	hsa-miR-3960	CLIP-seq
MIRT1292134	hsa-miR-4283	CLIP-seq
MIRT1292135	hsa-miR-4295	CLIP-seq
MIRT1292136	hsa-miR-4326	CLIP-seq
MIRT1292137	hsa-miR-4436b-3p	CLIP-seq
MIRT1292138	hsa-miR-4495	CLIP-seq
MIRT1292139	hsa-miR-4508	CLIP-seq
MIRT1292140	hsa-miR-454	CLIP-seq
MIRT1292141	hsa-miR-4717-3p	CLIP-seq
MIRT1292142	hsa-miR-4796-3p	CLIP-seq
MIRT1292143	hsa-miR-514	CLIP-seq
MIRT1292144	hsa-miR-514b-3p	CLIP-seq
MIRT1292145	hsa-miR-519a	CLIP-seq
MIRT1292146	hsa-miR-519b-3p	CLIP-seq
MIRT1292147	hsa-miR-519c-3p	CLIP-seq
MIRT1292148	hsa-miR-519d	CLIP-seq
MIRT1292149	hsa-miR-548ah	CLIP-seq
MIRT1292150	hsa-miR-599	CLIP-seq
MIRT1292151	hsa-miR-663	CLIP-seq
MIRT1292152	hsa-miR-744	CLIP-seq
MIRT1292153	hsa-miR-93	CLIP-seq
MIRT1292104	hsa-miR-106a	CLIP-seq
MIRT1292105	hsa-miR-106b	CLIP-seq
MIRT1292106	hsa-miR-130a	CLIP-seq
MIRT1292107	hsa-miR-130b	CLIP-seq
MIRT1292108	hsa-miR-17	CLIP-seq
MIRT1292110	hsa-miR-2052	CLIP-seq
MIRT1292111	hsa-miR-20a	CLIP-seq
MIRT1292112	hsa-miR-20b	CLIP-seq
MIRT1292113	hsa-miR-2113	CLIP-seq
MIRT1292114	hsa-miR-224	CLIP-seq
MIRT1292117	hsa-miR-301a	CLIP-seq
MIRT1292118	hsa-miR-301b	CLIP-seq
MIRT1292119	hsa-miR-30a	CLIP-seq
MIRT1292120	hsa-miR-30b	CLIP-seq
MIRT1292121	hsa-miR-30c	CLIP-seq
MIRT1292122	hsa-miR-30d	CLIP-seq
MIRT1292123	hsa-miR-30e	CLIP-seq
MIRT1292124	hsa-miR-3121-5p	CLIP-seq
MIRT1292126	hsa-miR-3609	CLIP-seq
MIRT1292127	hsa-miR-3614-5p	CLIP-seq
MIRT1292129	hsa-miR-3666	CLIP-seq
MIRT1292154	hsa-miR-3944-5p	CLIP-seq
MIRT1292135	hsa-miR-4295	CLIP-seq
MIRT1292136	hsa-miR-4326	CLIP-seq
MIRT1292138	hsa-miR-4495	CLIP-seq
MIRT1292140	hsa-miR-454	CLIP-seq
MIRT1292141	hsa-miR-4717-3p	CLIP-seq
MIRT1292142	hsa-miR-4796-3p	CLIP-seq
MIRT1292143	hsa-miR-514	CLIP-seq
MIRT1292144	hsa-miR-514b-3p	CLIP-seq
MIRT1292145	hsa-miR-519a	CLIP-seq
MIRT1292146	hsa-miR-519b-3p	CLIP-seq
MIRT1292147	hsa-miR-519c-3p	CLIP-seq
MIRT1292148	hsa-miR-519d	CLIP-seq
MIRT1292149	hsa-miR-548ah	CLIP-seq
MIRT1292150	hsa-miR-599	CLIP-seq
MIRT1292153	hsa-miR-93	CLIP-seq
MIRT1292113	hsa-miR-2113	CLIP-seq
MIRT1292150	hsa-miR-599	CLIP-seq
MIRT1292110	hsa-miR-2052	CLIP-seq
MIRT1292113	hsa-miR-2113	CLIP-seq
MIRT1292124	hsa-miR-3121-5p	CLIP-seq
MIRT1292154	hsa-miR-3944-5p	CLIP-seq
MIRT1292136	hsa-miR-4326	CLIP-seq
MIRT1292150	hsa-miR-599	CLIP-seq
MIRT1292104	hsa-miR-106a	CLIP-seq
MIRT1292105	hsa-miR-106b	CLIP-seq
MIRT1292106	hsa-miR-130a	CLIP-seq
MIRT1292107	hsa-miR-130b	CLIP-seq
MIRT1292108	hsa-miR-17	CLIP-seq
MIRT1292110	hsa-miR-2052	CLIP-seq
MIRT1292111	hsa-miR-20a	CLIP-seq
MIRT1292112	hsa-miR-20b	CLIP-seq
MIRT1292117	hsa-miR-301a	CLIP-seq
MIRT1292118	hsa-miR-301b	CLIP-seq
MIRT2439844	hsa-miR-3120-3p	CLIP-seq
MIRT1292126	hsa-miR-3609	CLIP-seq
MIRT2439845	hsa-miR-365	CLIP-seq
MIRT1292129	hsa-miR-3666	CLIP-seq
MIRT1292135	hsa-miR-4295	CLIP-seq
MIRT1292140	hsa-miR-454	CLIP-seq
MIRT2439846	hsa-miR-4725-5p	CLIP-seq
MIRT1292142	hsa-miR-4796-3p	CLIP-seq
MIRT2439847	hsa-miR-504	CLIP-seq
MIRT1292145	hsa-miR-519a	CLIP-seq
MIRT1292146	hsa-miR-519b-3p	CLIP-seq
MIRT1292147	hsa-miR-519c-3p	CLIP-seq
MIRT1292148	hsa-miR-519d	CLIP-seq
MIRT1292149	hsa-miR-548ah	CLIP-seq
MIRT1292153	hsa-miR-93	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005525	Function	GTP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0007165	Process	Signal transduction	TAS	10471929, 10673050
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS	10840027
GO:0007263	Process	Nitric oxide mediated signal transduction	IEA
GO:0016529	Component	Sarcoplasmic reticulum	IEA
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA

MIM	HGNC	e!Ensembl
605550	15828	ENSG00000108551

Protein

UniProt ID

Q9Y272

Protein name

Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1)

Protein function

Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00071	Ras	26 → 196	Ras family	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues. {ECO:0000269|PubMed:10673050, ECO:0000269|PubMed:128

Sequence

MKLAAMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDF
HRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQ
ILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKK
NSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPG
DAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS

Sequence length

281

Interactions

View interactions

	KEGG
	Circadian entrainment Cushing syndrome

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Insomnia	Insomnia			GWAS

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text Mining
ACTH Secreting Pituitary Adenoma	Associate	28487882
Allergic Fungal Sinusitis	Associate	29270391
Asthma	Associate	36012391
Atrophy	Associate	36130474
Breast Neoplasms	Associate	33255991
Carcinoma Non Small Cell Lung	Associate	34363324
Cardiomyopathy Hypertrophic	Associate	38006610
Drug Related Side Effects and Adverse Reactions	Associate	36130474
Graves Ophthalmopathy	Associate	35896115
Hereditary Breast and Ovarian Cancer Syndrome	Associate	36130474
Inflammation	Associate	35896115
Intellectual Disability	Associate	27459931
Leukemia Biphenotypic Acute	Associate	33357137
Leukemia Myeloid Acute	Associate	36951484
Neoplasms	Associate	28849149, 33357137, 34346294
Osteosarcoma	Associate	22292074
Parkinson Disease Secondary	Associate	27459931
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	33357137
Prostatic Neoplasms	Associate	37565899
Squamous Cell Carcinoma of Head and Neck	Associate	26159854

RASD1 (ras related dexamethasone induced 1)